{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T04:04:46Z","timestamp":1743480286267,"version":"3.40.3"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T00:00:00Z","timestamp":1722297600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T00:00:00Z","timestamp":1722297600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Skeletal Radiol"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>Vertebral body enhancement is occasionally seen on postcontrast CT imaging in the absence of osseous pathology. This enhancement can mimic sclerotic osseous metastatic disease, leading to a diagnostic dilemma for radiologists and increasing the chance of misinterpretation. Existing literature has focused on the association between this enhancement and concomitant central venous system obstruction. We report a 61-year-old woman with a history of nasopharyngeal carcinoma presenting with an epidural abscess who exhibited vertebral body enhancement resembling sclerotic metastatic disease without imaging evidence of central venous obstruction or vertebral osseous metastatic disease. Awareness of this unique presentation may prevent the incorrect diagnostic errors and their associated negative effects on patients.<\/jats:p>","DOI":"10.1007\/s00256-024-04761-w","type":"journal-article","created":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T22:01:45Z","timestamp":1722376905000},"page":"1133-1138","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intravertebral collateral enhancement resembling sclerotic metastatic disease in a case of cervical epidural abscess"],"prefix":"10.1007","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-3545-7654","authenticated-orcid":false,"given":"Daniel K.","family":"Schneider","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet Hakan","family":"Ok","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claus S.","family":"Simpfendorfer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael C.","family":"Forney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naveen","family":"Subhas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,7,30]]},"reference":[{"issue":"6","key":"4761_CR1","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1002\/jmri.24247","volume":"38","author":"C Mugera","year":"2013","unstructured":"Mugera C, Suh KJ, Huisman TAGM, et al. Sclerotic lesions of the spine: MRI assessment. J Magn Reson Imaging. 2013;38(6):1310\u201324.","journal-title":"J Magn Reson Imaging"},{"issue":"11","key":"4761_CR2","doi-asserted-by":"crossref","first-page":"587","DOI":"10.5435\/00124635-200610000-00001","volume":"14","author":"AP White","year":"2006","unstructured":"White AP, Kwon BK, Lindskog DM, et al. Metastatic disease of the spine. J Am Acad Orthop Surg. 2006;14(11):587\u201398.","journal-title":"J Am Acad Orthop Surg"},{"issue":"4","key":"4761_CR3","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1200\/JCO.2005.03.8760","volume":"24","author":"FY Liu","year":"2006","unstructured":"Liu FY, Chang JT, Wang HM, et al. [18F] fluorodeoxyglucose positron emission tomography is more sensitive than skeletal scintigraphy for detecting bone metastasis in endemic nasopharyngeal carcinoma at initial staging. J Clin Onc. 2006;24(4):599\u2013604.","journal-title":"J Clin Onc"},{"issue":"4","key":"4761_CR4","first-page":"229","volume":"12","author":"CJ Huang","year":"1996","unstructured":"Huang CJ, Leung SW, Lian SL, et al. Patterns of distant metastases in nasopharyngeal carcinoma. Kaohsiung J Med Sci. 1996;12(4):229\u201334.","journal-title":"Kaohsiung J Med Sci"},{"issue":"6","key":"4761_CR5","doi-asserted-by":"crossref","first-page":"W344","DOI":"10.2214\/AJR.08.2068","volume":"192","author":"RA Jesinger","year":"2009","unstructured":"Jesinger RA, Huynh B, Gover D. Superior vena cava syndrome resulting in osseous venous congestion simulating sclerotic bone lesions. AJR Am J Roentgenol. 2009;192(6):W344\u20135.","journal-title":"AJR Am J Roentgenol"},{"issue":"2","key":"4761_CR6","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s00256-014-2037-9","volume":"44","author":"D Berritto","year":"2015","unstructured":"Berritto D, Abboud S, Kosmas C, et al. Vertebral body enhancement mimicking sclerotic osseous lesions in the setting of bilateral brachiocephalic vein thrombosis. Skeletal Radiol. 2015;44(2):303\u20135.","journal-title":"Skeletal Radiol"},{"issue":"11","key":"4761_CR7","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1097\/RLU.0b013e3182a20daa","volume":"38","author":"O Rager","year":"2013","unstructured":"Rager O, Nkoulou R, Garibotto V, et al. Spinal uptake mimicking metastasis in SPECT\/CT bone scan in a patient with superior vena cava obstruction. Clin Nucl Med. 2013;38(11):908\u20139.","journal-title":"Clin Nucl Med"},{"issue":"6","key":"4761_CR8","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/j.spinee.2013.07.440","volume":"15","author":"YK Kim","year":"2015","unstructured":"Kim YK, Sung YM, Hwang KH, et al. Pseudopathologic vertebral body enhancement in the presence of superior vena cava obstruction on computed tomography. Spine J. 2015;15(6):1295\u2013301.","journal-title":"Spine J"},{"issue":"1005","key":"4761_CR9","doi-asserted-by":"crossref","first-page":"e176","DOI":"10.1259\/bjr\/50676625","volume":"84","author":"N Thomas","year":"2011","unstructured":"Thomas N, Oliver TB, Sudarshan T. Vanishing bone metastases: a pitfall in the interpretation of contrast enhanced CT in patients with superior vena cava obstruction. Br J Radiol. 2011;84(1005):e176\u20138.","journal-title":"Br J Radiol"},{"issue":"2","key":"4761_CR10","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s00256-015-2274-6","volume":"45","author":"FJ Simeone","year":"2016","unstructured":"Simeone FJ, Bennett DL, Chang CY, et al. Retrospective analysis of intravertebral collateral enhancement in patients with central venous obstruction. 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Philadelphia, PA: Elsevier; 2020. p. 809- 30.e3.","edition":"6"}],"container-title":["Skeletal Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00256-024-04761-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00256-024-04761-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00256-024-04761-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T13:36:26Z","timestamp":1743428186000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00256-024-04761-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,30]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["4761"],"URL":"https:\/\/doi.org\/10.1007\/s00256-024-04761-w","relation":{},"ISSN":["0364-2348","1432-2161"],"issn-type":[{"type":"print","value":"0364-2348"},{"type":"electronic","value":"1432-2161"}],"subject":[],"published":{"date-parts":[[2024,7,30]]},"assertion":[{"value":"20 April 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 July 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 July 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 July 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Informed consent for the study was obtained in accordance with institutional and journal guidelines and documented in the electronic medical record. The patient granted permission to include deidentified patient data and images in the research case report study titled \u201cIntravertebral collateral enhancement resembling sclerotic metastatic disease in a case of cervical epidural abscess.\u201d The risks, benefits, and anticipated outcomes of the study, the alternatives to the study and the risks and benefits of those alternatives, and the roles and tasks of the personnel to be involved in the study were discussed with the patient. The patient\u2019s questions were answered to their satisfaction and they agreed to be included in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Patient consent"}}]}}