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Additionally, two radiologists qualitatively assessed MFC, AT quality, and co-pathologies. 2pt-MRI<jats:sub>DIXON<\/jats:sub>-derived fat fractions (FF) were related to patients\u2019 demographics and qualitative imaging findings.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The overall mean FF derived from 2pt-MRI<jats:sub>DIXON<\/jats:sub> of the triceps surae muscle was 11.2\u2009\u00b1\u20099.3%. Comparing midportion and insertional ATD, there was no significant difference regarding fatty muscle infiltration assessed with 2pt-MRI<jats:sub>DIXON<\/jats:sub> (<jats:italic>P<\/jats:italic>\u2009\u2265\u2009.47) or qualitative grading (<jats:italic>P<\/jats:italic>\u2009\u2265\u2009.059). More severe AT thickening (11 vs.9\u00a0mm, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001) and complete tears (29 vs. 9%, <jats:italic>P<\/jats:italic>\u2009=\u2009.025) were significantly more common in midportion ATD, while partial tears were significantly more frequent in insertional ATD (55 vs. 31%, <jats:italic>P<\/jats:italic>\u2009=\u2009.027). Soleus muscle edema was more prevalent in midportion than insertional ATD (40 vs. 9%, <jats:italic>P<\/jats:italic>\u2009=\u2009.002). In contrast, insertional ATD more commonly featured bone marrow edema (61 vs. 2%), Haglund\u2019s deformity (67 vs. 0%), and retrocalcaneal bursitis (82 vs. 43%) (<jats:italic>P<\/jats:italic>\u2009\u2264\u2009.002). Significant correlations (<jats:italic>P<\/jats:italic>\u2009\u2264\u2009.001) were demonstrated between FF, AT diameter, age (both in midportion and insertional ATD), and body mass index (in midportion ATD only) (<jats:italic>\u03c1<\/jats:italic>\u00a0range\u2009=\u20090.53\u20130.61).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>In chronic ATD, calf MFC was statistically equivalent (approximately 11%), irrespective of the localization of tendon damage. More severe tendon thickening and complete tears were more common in midportion ATD, and, vice versa, partial AT tears were significantly more frequent in insertional ATD.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00256-024-04845-7","type":"journal-article","created":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T07:51:17Z","timestamp":1733903477000},"page":"1457-1468","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Assessment of calf muscle constitution in chronic Achilles tendon disease using Dixon-based MRI"],"prefix":"10.1007","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0964-8386","authenticated-orcid":false,"given":"Sophia S.","family":"Goller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg W.","family":"Kajdi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Wirth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jess G.","family":"Snedeker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reto","family":"Sutter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,12,11]]},"reference":[{"key":"4845_CR1","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1016\/S0278-5919(20)30506-8","volume":"11","author":"PV Komi","year":"1992","unstructured":"Komi PV, Fukashiro S, Jarvinen M. 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