{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T08:44:50Z","timestamp":1779093890900,"version":"3.51.4"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T00:00:00Z","timestamp":1743984000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T00:00:00Z","timestamp":1743984000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Skeletal Radiol"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1007\/s00256-025-04924-3","type":"journal-article","created":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T01:23:58Z","timestamp":1744075438000},"page":"1803-1810","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Assessment of neurovascular bundle involvement by an extremity sarcoma on MRI: a critical decision for sarcoma surgeon"],"prefix":"10.1007","volume":"54","author":[{"given":"Dharmendra Kumar","family":"Singh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Divesh","family":"Jalan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aarushi","family":"Narwani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nishith","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashish","family":"Rustagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfa Shamim","family":"Saifi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Upinderjeet","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Supriya","family":"Kaur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8768-8730","authenticated-orcid":false,"given":"Neha","family":"Nischal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,4,7]]},"reference":[{"issue":"3","key":"4924_CR1","doi-asserted-by":"publisher","first-page":"138","DOI":"10.4103\/2278-330X.187587","volume":"5","author":"A Ramaswamy","year":"2016","unstructured":"Ramaswamy A, Rekhi B, Bakhshi S, Hingmire S, Agarwal M. Indian data on bone and soft tissue sarcomas: a summary of published study results. South Asian J Cancer. 2016;5(3):138\u201345. https:\/\/doi.org\/10.4103\/2278-330X.187587.","journal-title":"South Asian J Cancer"},{"issue":"2","key":"4924_CR2","doi-asserted-by":"publisher","first-page":"e0246958","DOI":"10.1371\/journal.pone.0246958","volume":"16","author":"G de Pinieux","year":"2021","unstructured":"de Pinieux G, Karanian M, Le Loarer F, Le Guellec S, Chabaud S, Terrier P, et al. Nationwide incidence of sarcomas and connective tissue tumors of intermediate malignancy over four years using an expert pathology review network. PLoS ONE. 2021;16(2):e0246958. https:\/\/doi.org\/10.1371\/journal.pone.0246958.","journal-title":"PLoS ONE"},{"issue":"5","key":"4924_CR3","doi-asserted-by":"publisher","first-page":"271","DOI":"10.3322\/canjclin.31.5.271","volume":"31","author":"SI Hajdu","year":"1981","unstructured":"Hajdu SI. Soft tissue sarcomas: classification and natural history. CA Cancer J Clin. 1981;31(5):271\u201380. https:\/\/doi.org\/10.3322\/canjclin.31.5.271.","journal-title":"CA Cancer J Clin"},{"issue":"5","key":"4924_CR4","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.diii.2022.12.001","volume":"104","author":"A Cromb\u00e9","year":"2023","unstructured":"Cromb\u00e9 A, Kind M, Fadli D, Miceli M, Linck PA, Bianchi G, et al. Soft-tissue sarcoma in adults: imaging appearances, pitfalls and diagnostic algorithms. Diagn Interv Imaging. 2023;104(5):207\u201320. https:\/\/doi.org\/10.1016\/j.diii.2022.12.001.","journal-title":"Diagn Interv Imaging"},{"issue":"8","key":"4924_CR5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0020294","volume":"6","author":"F Ducimeti\u00e8re","year":"2011","unstructured":"Ducimeti\u00e8re F, Lurkin A, Ranch\u00e8re-Vince D, Decouvelaere AV, P\u00e9oc\u2019h M, Istier L, et al. Incidence of sarcoma histotypes and molecular subtypes in a prospective epidemiological study with central pathology review and molecular testing. PLoS ONE. 2011;6(8): e20294. https:\/\/doi.org\/10.1371\/journal.pone.0020294.","journal-title":"PLoS ONE"},{"key":"4924_CR6","unstructured":"Demetri GD, Baker LH, Beech D, Benjamin R, Casper ES, Conrad EU 3rd, et al. National Comprehensive Cancer Network. Soft tissue sarcoma clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2005;3(2):158\u201394."},{"issue":"3","key":"4924_CR7","doi-asserted-by":"publisher","first-page":"200","DOI":"10.3322\/caac.21605","volume":"70","author":"AC Gamboa","year":"2020","unstructured":"Gamboa AC, Gronchi A, Cardona K. Soft-tissue sarcoma in adults: an update on the current state of histiotype-specific management in an era of personalized medicine. CA Cancer J Clin. 2020;70(3):200\u201329. https:\/\/doi.org\/10.3322\/caac.21605.","journal-title":"CA Cancer J Clin"},{"key":"4924_CR8","doi-asserted-by":"publisher","first-page":"91","DOI":"10.33590\/emjoncol\/20-00084","volume":"2","author":"N Tamimi","year":"2021","unstructured":"Tamimi N, Sweiti H. Management of lower limb soft tissue sarcomas with major neurovascular involvement: current and future perspectives. EMJ Oncol. 2021;2:91\u20139.","journal-title":"EMJ Oncol"},{"issue":"2","key":"4924_CR9","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1148\/radiol.14140510","volume":"275","author":"K Holzapfel","year":"2015","unstructured":"Holzapfel K, Regler J, Baum T, Rechl H, Specht K, Haller B, et al. Local staging of soft-tissue sarcoma: emphasis on assessment of neurovascular encasement-value of MR imaging in 174 confirmed cases. Radiology. 2015;275(2):501\u20139. https:\/\/doi.org\/10.1148\/radiol.14140510.","journal-title":"Radiology"},{"issue":"2","key":"4924_CR10","doi-asserted-by":"publisher","first-page":"94","DOI":"10.3322\/canjclin.54.2.94","volume":"54","author":"JN Cormier","year":"2004","unstructured":"Cormier JN, Pollock RE. Soft tissue sarcomas. CA Cancer J Clin. 2004;54(2):94\u2013109. https:\/\/doi.org\/10.3322\/canjclin.54.2.94.","journal-title":"CA Cancer J Clin"},{"issue":"6","key":"4924_CR11","doi-asserted-by":"publisher","first-page":"1931","DOI":"10.1148\/rg.2016160084","volume":"36","author":"MJ Kransdorf","year":"2016","unstructured":"Kransdorf MJ, Murphey MD. Imaging of soft-tissue musculoskeletal masses: fundamental concepts. Radiographics. 2016;36(6):1931\u201348. https:\/\/doi.org\/10.1148\/rg.2016160084.","journal-title":"Radiographics"},{"issue":"5","key":"4924_CR12","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1016\/j.ijrobp.2004.08.036","volume":"61","author":"LM White","year":"2005","unstructured":"White LM, Wunder JS, Bell RS, O\u2019Sullivan B, Catton C, Ferguson P, et al. Histologic assessment of peritumoral edema in soft tissue sarcoma. Int J Radiat Oncol Biol Phys. 2005;61(5):1439\u201345. https:\/\/doi.org\/10.1016\/j.ijrobp.2004.08.036.","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"12","key":"4924_CR13","doi-asserted-by":"publisher","first-page":"1667","DOI":"10.1007\/s00256-017-2745-z","volume":"46","author":"PM De La Hoz","year":"2017","unstructured":"De La Hoz PM, Dick E, Bhumbra R, Pollock R, Sandhu R, Saifuddin A. Surgical considerations when reporting MRI studies of soft tissue sarcoma of the limbs. Skeletal Radiol. 2017;46(12):1667\u201378. https:\/\/doi.org\/10.1007\/s00256-017-2745-z.","journal-title":"Skeletal Radiol"},{"issue":"3","key":"4924_CR14","doi-asserted-by":"publisher","first-page":"615","DOI":"10.2214\/ajr.150.3.615","volume":"150","author":"BE Demas","year":"1988","unstructured":"Demas BE, Heelan RT, Lane J, Marcove R, Hajdu S, Brennan MF. Soft-tissue sarcomas of the extremities: comparison of MR and CT in determining the extent of disease. AJR Am J Roentgenol. 1988;150(3):615\u201320. https:\/\/doi.org\/10.2214\/ajr.150.3.615.","journal-title":"AJR Am J Roentgenol"},{"issue":"1","key":"4924_CR15","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1148\/radiol.2291020377","volume":"229","author":"DA Elias","year":"2003","unstructured":"Elias DA, White LM, Simpson DJ, Kandel RA, Tomlinson G, Bell RS, Wunder JS. Osseous invasion by soft-tissue sarcoma: assessment with MR imaging. Radiology. 2003;229(1):145\u201352. https:\/\/doi.org\/10.1148\/radiol.2291020377.","journal-title":"Radiology"},{"issue":"3","key":"4924_CR16","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1007\/s13193-021-01376-8","volume":"12","author":"A Raja","year":"2021","unstructured":"Raja A, Ramanujan V, Krishnan CK, Patel V. In situ preparation for nerve preservation in extremity soft tissue sarcoma. Point of Surgical Technique. Indian J Surg Oncol. 2021;12(3):641\u20136. https:\/\/doi.org\/10.1007\/s13193-021-01376-8.","journal-title":"Indian J Surg Oncol."},{"issue":"1","key":"4924_CR17","doi-asserted-by":"publisher","first-page":"22","DOI":"10.5758\/vsi.200064","volume":"37","author":"A Shah","year":"2021","unstructured":"Shah A, Ramanujan V, Muralidharan K, AnRaja A. Outcomes of vascular resection and reconstruction in extremity soft tissue sarcoma and bone tumors. Vasc Specialist Int. 2021;37(1):22\u20138. https:\/\/doi.org\/10.5758\/vsi.200064.","journal-title":"Vasc Specialist Int"},{"key":"4924_CR18","doi-asserted-by":"publisher","unstructured":"Robinson E, Bleakney RR, Ferguson PC, O\u2019Sullivan B. Oncodiagnosis panel: 2007: multidisciplinary management of soft-tissue sarcoma. Radiographics. 2008;28(7):2069\u201386. https:\/\/doi.org\/10.1148\/rg.287085167.","DOI":"10.1148\/rg.287085167"},{"issue":"4","key":"4924_CR19","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.2214\/AJR.09.2501","volume":"194","author":"F Khosa","year":"2010","unstructured":"Khosa F, Otero HJ, Prevedello LM, Rybicki FJ, Di Salvo DN. Imaging presentation of venous thrombosis in patients with cancer. AJR Am J Roentgenol. 2010;194(4):1099\u2013108. https:\/\/doi.org\/10.2214\/AJR.09.2501.","journal-title":"AJR Am J Roentgenol"},{"issue":"3","key":"4924_CR20","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1148\/radiology.205.3.9393550","volume":"205","author":"DM Panicek","year":"1997","unstructured":"Panicek DM, Go SD, Healey JH, Leung DH, Brennan MF, Lewis JJ. Soft-tissue sarcoma involving bone or neurovascular structures: MR imaging prognostic factors. Radiology. 1997;205(3):871\u20135. https:\/\/doi.org\/10.1148\/radiology.205.3.9393550.","journal-title":"Radiology"},{"issue":"1","key":"4924_CR21","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1148\/radiology.202.1.8988217","volume":"202","author":"DM Panicek","year":"1997","unstructured":"Panicek DM, Gatsonis C, Rosenthal DI, Seeger LL, Huvos AG, Moore SG, et al. CT and MR imaging in the local staging of primary malignant musculoskeletal neoplasms: report of the Radiology Diagnostic Oncology Group. Radiology. 1997;202(1):237\u201346. https:\/\/doi.org\/10.1148\/radiology.202.1.8988217.","journal-title":"Radiology"},{"key":"4924_CR22","unstructured":"Campanacci M. Introduction. In: Campa nacci M, editor. Bone and soft tissue tumors: clinical features, imaging, pathology and treatment. 2nd ed. Padua: Springer, 1999. pp. 61\u201363."},{"key":"4924_CR23","unstructured":"Thomas JE, Piepgras DG, Scheithauer B, Onofrio BM, Shives TC. Neurogenic tumors of the sciatic nerve. A clinicopathologic study of 35 cases. Mayo Clin Proc. 1983;58(10):640\u20137."},{"issue":"1","key":"4924_CR24","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1097\/00000658-198207000-00018","volume":"196","author":"AE Giuliano","year":"1982","unstructured":"Giuliano AE, Eilber FR, Morton DL. The management of locally recurrent soft-tissue sarcoma. Ann Surg. 1982;196(1):87\u201391. https:\/\/doi.org\/10.1097\/00000658-198207000-00018.","journal-title":"Ann Surg"},{"issue":"3","key":"4924_CR25","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1097\/00000658-198209000-00009","volume":"196","author":"SA Rosenberg","year":"1982","unstructured":"Rosenberg SA, Tepper J, Glatstein E, Costa J, Baker A, Brennan M, DeMoss EV, Seipp C, Sindelar WF, Sugarbaker P, Wesley R. The treatment of soft-tissue sarcomas of the extremities: prospective randomized evaluations of (1) limb-sparing surgery plus radiation therapy compared with amputation and (2) the role of adjuvant chemotherapy. Ann Surg. 1982;196(3):305\u201315. https:\/\/doi.org\/10.1097\/00000658-198209000-00009.","journal-title":"Ann Surg"},{"issue":"4","key":"4924_CR26","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1002\/jso.2930250410","volume":"25","author":"RN Nambisan","year":"1984","unstructured":"Nambisan RN, Rao U, Moore R, Karakousis CP. Malignant soft tissue tumors of nerve sheath origin. J Surg Oncol. 1984;25(4):268\u201372. https:\/\/doi.org\/10.1002\/jso.2930250410.","journal-title":"J Surg Oncol"},{"issue":"4","key":"4924_CR27","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1097\/COC.0b013e318173a54f","volume":"32","author":"WM Mendenhall","year":"2009","unstructured":"Mendenhall WM, Indelicato DJ, Scarborough MT, Zlotecki RA, Gibbs CP, Mendenhall NP, et al. The management of adult soft tissue sarcomas. Am J Clin Oncol. 2009;32(4):436\u201342. https:\/\/doi.org\/10.1097\/COC.0b013e318173a54f.","journal-title":"Am J Clin Oncol"},{"issue":"5","key":"4924_CR28","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1016\/j.suc.2016.05.001","volume":"96","author":"AM Crago","year":"2016","unstructured":"Crago AM, Lee AY. Multimodality management of soft tissue tumors in the extremity. Surg Clin North Am. 2016;96(5):977\u201392. https:\/\/doi.org\/10.1016\/j.suc.2016.05.001.","journal-title":"Surg Clin North Am"},{"issue":"8","key":"4924_CR29","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1302\/0301-620x.83b8.12028","volume":"83","author":"CH Gerrand","year":"2001","unstructured":"Gerrand CH, Wunder JS, Kandel RA, O\u2019Sullivan B, Catton CN, Bell RS, et al. Classification of positive margins after resection of soft-tissue sarcoma of the limb predicts the risk of local recurrence. J Bone Joint Surg Br. 2001;83(8):1149\u201355. https:\/\/doi.org\/10.1302\/0301-620x.83b8.12028.","journal-title":"J Bone Joint Surg Br"},{"issue":"4","key":"4924_CR30","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1016\/j.soc.2016.05.014","volume":"25","author":"MG Cable","year":"2016","unstructured":"Cable MG, Randall RL. Extremity soft tissue sarcoma: tailoring resection to histologic subtype. Surg Oncol Clin N Am. 2016;25(4):677\u201395. https:\/\/doi.org\/10.1016\/j.soc.2016.05.014.","journal-title":"Surg Oncol Clin N Am"},{"issue":"19","key":"4924_CR31","doi-asserted-by":"publisher","first-page":"2952","DOI":"10.1002\/cncr.30191","volume":"122","author":"R Ratan","year":"2016","unstructured":"Ratan R, Patel SR. Chemotherapy for soft tissue sarcoma. Cancer. 2016;122(19):2952\u201360. https:\/\/doi.org\/10.1002\/cncr.30191.","journal-title":"Cancer"},{"issue":"1","key":"4924_CR32","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1002\/bjs.4004","volume":"90","author":"MA Clark","year":"2003","unstructured":"Clark MA, Thomas JM. Major amputation for soft-tissue sarcoma. Br J Surg. 2003;90(1):102\u20137. https:\/\/doi.org\/10.1002\/bjs.4004.","journal-title":"Br J Surg"}],"container-title":["Skeletal Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00256-025-04924-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00256-025-04924-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00256-025-04924-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T10:21:11Z","timestamp":1757154071000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00256-025-04924-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,7]]},"references-count":32,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["4924"],"URL":"https:\/\/doi.org\/10.1007\/s00256-025-04924-3","relation":{},"ISSN":["0364-2348","1432-2161"],"issn-type":[{"value":"0364-2348","type":"print"},{"value":"1432-2161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,7]]},"assertion":[{"value":"8 November 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 February 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 March 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 April 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Not required.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval, consent to participate, and consent for publication"}}]}}