{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T08:02:49Z","timestamp":1791187369169,"version":"4.1.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Nucl Med Mol Imaging"],"published-print":{"date-parts":[[2010,7]]},"DOI":"10.1007\/s00259-009-1363-y","type":"journal-article","created":{"date-parts":[[2010,1,28]],"date-time":"2010-01-28T13:12:21Z","timestamp":1264684341000},"page":"1345-1355","source":"Crossref","is-referenced-by-count":124,"title":["68Ga-labelled exendin-3, a new agent for the detection of insulinomas with PET"],"prefix":"10.1007","volume":"37","author":[{"given":"Maarten","family":"Brom","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wim J. G.","family":"Oyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lieke","family":"Joosten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Gotthardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otto C.","family":"Boerman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,1,29]]},"reference":[{"key":"1363_CR1","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1053\/gast.1997.v112.pm9024313","volume":"112","author":"IM Modlin","year":"1997","unstructured":"Modlin IM, Tang LH. Approaches to the diagnosis of gut neuroendocrine tumors: the last word (today). Gastroenterology 1997;112:583\u201390.","journal-title":"Gastroenterology"},{"key":"1363_CR2","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1007\/BF00181765","volume":"20","author":"EP Krenning","year":"1993","unstructured":"Krenning EP, Kwekkeboom DJ, Bakker WH, Breeman WA, Kooij PP, Oei HY, et al. Somatostatin receptor scintigraphy with [111In-DTPA-D-Phe1]- and [123I-Tyr3]-octreotide: the Rotterdam experience with more than 1000 patients. Eur J Nucl Med 1993;20:716\u201331.","journal-title":"Eur J Nucl Med"},{"key":"1363_CR3","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1055\/s-0038-1632294","volume":"32","author":"K Joseph","year":"1993","unstructured":"Joseph K, Stapp J, Reinecke J, Skamel HJ, Hoffken H, Benning R, et al. Receptor scintigraphy using 111In-pentetreotide in endocrine gastroenteropancreatic tumors. Nuklearmedizin 1993;32:299\u2013305.","journal-title":"Nuklearmedizin"},{"key":"1363_CR4","doi-asserted-by":"crossref","first-page":"657","DOI":"10.3748\/wjg.14.657","volume":"14","author":"B Abboud","year":"2008","unstructured":"Abboud B, Boujaoude J. Occult sporadic insulinoma: localization and surgical strategy. World J Gastroenterol 2008;14:657\u201365.","journal-title":"World J Gastroenterol"},{"key":"1363_CR5","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.beem.2004.10.002","volume":"19","author":"JE Jackson","year":"2005","unstructured":"Jackson JE. Angiography and arterial stimulation venous sampling in the localization of pancreatic neuroendocrine tumours. Best Pract Res Clin Endocrinol Metab 2005;19:229\u201339.","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"1363_CR6","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1007\/s00259-003-1184-3","volume":"30","author":"JC Reubi","year":"2003","unstructured":"Reubi JC, Waser B. Concomitant expression of several peptide receptors in neuroendocrine tumours: molecular basis for in vivo multireceptor tumour targeting. Eur J Nucl Med Mol Imaging 2003;30:781\u201393.","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"1363_CR7","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1007\/s00259-002-0761-1","volume":"29","author":"M Gotthardt","year":"2002","unstructured":"Gotthardt M, Fischer M, Naeher I, Holz JB, Jungclas H, Fritsch HW, et al. Use of the incretin hormone glucagon-like peptide-1 (GLP-1) for the detection of insulinomas: initial experimental results. Eur J Nucl Med Mol Imaging 2002;29:597\u2013606.","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"1363_CR8","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0167-0115(94)90158-9","volume":"53","author":"G Singh","year":"1994","unstructured":"Singh G, Eng J, Raufman JP. Use of 125I-[Y39]exendin-4 to characterize exendin receptors on dispersed pancreatic acini and gastric chief cells from guinea pig. Regul Pept 1994;53:47\u201359.","journal-title":"Regul Pept"},{"key":"1363_CR9","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0969-8051(98)00121-8","volume":"26","author":"M Hassan","year":"1999","unstructured":"Hassan M, Eskilsson A, Nilsson C, Jonsson C, Jacobsson H, Refai E, et al. In vivo dynamic distribution of 131I-glucagon-like peptide-1 (7-36) amide in the rat studied by gamma camera. Nucl Med Biol 1999;26:413\u201320.","journal-title":"Nucl Med Biol"},{"key":"1363_CR10","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.2174\/1381612043383502","volume":"10","author":"M Gotthardt","year":"2004","unstructured":"Gotthardt M, Boermann OC, Behr TM, Behe MP, Oyen WJ. Development and clinical application of peptide-based radiopharmaceuticals. Curr Pharm Des 2004;10:2951\u201363.","journal-title":"Curr Pharm Des"},{"key":"1363_CR11","doi-asserted-by":"crossref","first-page":"2294","DOI":"10.1111\/j.1460-9568.1995.tb00650.x","volume":"7","author":"R Goke","year":"1995","unstructured":"Goke R, Larsen PJ, Mikkelsen JD, Sheikh SP. Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites. Eur J Neurosci 1995;7:2294\u2013300.","journal-title":"Eur J Neurosci"},{"key":"1363_CR12","first-page":"2025","volume":"47","author":"D Wild","year":"2006","unstructured":"Wild D, Behe M, Wicki A, Storch D, Waser B, Gotthardt M, et al. [Lys40(Ahx-DTPA-111In)NH2]exendin-4, a very promising ligand for glucagon-like peptide-1 (GLP-1) receptor targeting. J Nucl Med 2006;47:2025\u201333.","journal-title":"J Nucl Med"},{"key":"1363_CR13","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.regpep.2006.07.005","volume":"137","author":"M Gotthardt","year":"2006","unstructured":"Gotthardt M, Lalyko G, van Eerd-Vismale J, Keil B, Schurrat T, Hower M, et al. A new technique for in vivo imaging of specific GLP-1 binding sites: first results in small rodents. Regul Pept 2006;137:162\u20137.","journal-title":"Regul Pept"},{"key":"1363_CR14","doi-asserted-by":"crossref","first-page":"3696","DOI":"10.1158\/1078-0432.CCR-06-2965","volume":"13","author":"A Wicki","year":"2007","unstructured":"Wicki A, Wild D, Storch D, Seemayer C, Gotthardt M, Behe M, et al. [Lys40(Ahx-DTPA-111In)NH2]-Exendin-4 is a highly efficient radiotherapeutic for glucagon-like peptide-1 receptor-targeted therapy for insulinoma. Clin Cancer Res 2007;13:3696\u2013705.","journal-title":"Clin Cancer Res"},{"key":"1363_CR15","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1056\/NEJMc0802045","volume":"359","author":"D Wild","year":"2008","unstructured":"Wild D, Macke H, Christ E, Gloor B, Reubi JC. Glucagon-like peptide 1-receptor scans to localize occult insulinomas. N Engl J Med 2008;359:766\u20138.","journal-title":"N Engl J Med"},{"key":"1363_CR16","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1210\/endo.130.1.1370150","volume":"130","author":"M Asfari","year":"1992","unstructured":"Asfari M, Janjic D, Meda P, Li G, Halban PA, Wollheim CB. Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology 1992;130:167\u201378.","journal-title":"Endocrinology"},{"key":"1363_CR17","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1007\/s00259-007-0604-1","volume":"35","author":"P Laverman","year":"2008","unstructured":"Laverman P, Roosenburg S, Gotthardt M, Park J, Oyen WJ, de Jong M, et al. Targeting of a CCK(2) receptor splice variant with (111)In-labelled cholecystokinin-8 (CCK8) and (111)In-labelled minigastrin. Eur J Nucl Med Mol Imaging 2008;35:386\u201392.","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"1363_CR18","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1210\/jc.2006-1479","volume":"92","author":"S Kauhanen","year":"2007","unstructured":"Kauhanen S, Seppanen M, Minn H, Gullichsen R, Salonen A, Alanen K, et al. Fluorine-18-L-dihydroxyphenylalanine (18F-DOPA) positron emission tomography as a tool to localize an insulinoma or beta-cell hyperplasia in adult patients. J Clin Endocrinol Metab 2007;92:1237\u201344.","journal-title":"J Clin Endocrinol Metab"},{"key":"1363_CR19","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1007\/s00259-007-0450-1","volume":"34","author":"I Buchmann","year":"2007","unstructured":"Buchmann I, Henze M, Engelbrecht S, Eisenhut M, Runz A, Schafer M, et al. Comparison of 68Ga-DOTATOC PET and 111In-DTPAOC (Octreoscan) SPECT in patients with neuroendocrine tumours. Eur J Nucl Med Mol Imaging 2007;34:1617\u201326.","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"1363_CR20","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S1536-1632(03)00038-6","volume":"5","author":"J Kowalski","year":"2003","unstructured":"Kowalski J, Henze M, Schuhmacher J, Macke HR, Hofmann M, Haberkorn U. Evaluation of positron emission tomography imaging using [68Ga]-DOTA-D Phe(1)-Tyr(3)-octreotide in comparison to [111In]-DTPAOC SPECT. First results in patients with neuroendocrine tumors. Mol Imaging Biol 2003;5:42\u20138.","journal-title":"Mol Imaging Biol"},{"key":"1363_CR21","doi-asserted-by":"crossref","unstructured":"van Dalen JA, Visser EP, Laverman P, Vogel WV, Oyen WJG, Corstens FHM, et al. Effect of the positron range on the spatial resolution of a new generation pre-clinical PET using fluorine-18, gallium-68, zirconium-89 and iodine-124. Eur J Nucl Med Mol Imaging 2007;34:S228-S.","DOI":"10.1118\/1.2437283"},{"key":"1363_CR22","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s002590050034","volume":"27","author":"JC Reubi","year":"2000","unstructured":"Reubi JC, Schar JC, Waser B, Wenger S, Heppeler A, Schmitt JS, et al. Affinity profiles for human somatostatin receptor subtypes SST1-SST5 of somatostatin radiotracers selected for scintigraphic and radiotherapeutic use. Eur J Nucl Med 2000;27:273\u201382.","journal-title":"Eur J Nucl Med"},{"key":"1363_CR23","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1007\/s00259-006-0317-x","volume":"34","author":"P Antunes","year":"2007","unstructured":"Antunes P, Ginj M, Zhang H, Waser B, Baum RP, Reubi JC, et al. Are radiogallium-labelled DOTA-conjugated somatostatin analogues superior to those labelled with other radiometals? Eur J Nucl Med Mol Imaging 2007;34:982\u201393.","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"1363_CR24","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1007\/s00259-004-1702-y","volume":"32","author":"WA Breeman","year":"2005","unstructured":"Breeman WA, de Jong M, de Blois E, Bernard BF, Konijnenberg M, Krenning EP. Radiolabelling DOTA-peptides with 68Ga. Eur J Nucl Med Mol Imaging 2005;32:478\u201385.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"Suppl 50","key":"1363_CR25","first-page":"147","volume":"50","author":"M Brom","year":"2009","unstructured":"Brom M, Baumeister P, Melis M, Laverman P, Joosten L, Behe M, et al. Determination of the beta-cell mass by SPECT imaging with In-111-DTPA-Exendin-3 in rats. J Nucl Med 2009;50(Suppl 2):147.","journal-title":"J Nucl Med"}],"container-title":["European Journal of Nuclear Medicine and Molecular Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.springerlink.com\/index\/pdf\/10.1007\/s00259-009-1363-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,25]],"date-time":"2019-05-25T12:16:06Z","timestamp":1558786566000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00259-009-1363-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,29]]},"references-count":25,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["1363"],"URL":"https:\/\/doi.org\/10.1007\/s00259-009-1363-y","relation":{},"ISSN":["1619-7070","1619-7089"],"issn-type":[{"value":"1619-7070","type":"print"},{"value":"1619-7089","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,29]]}}}