{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:12:56Z","timestamp":1761059576362},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2013,8,9]],"date-time":"2013-08-09T00:00:00Z","timestamp":1376006400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Nucl Med Mol Imaging"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1007\/s00259-013-2524-6","type":"journal-article","created":{"date-parts":[[2013,8,8]],"date-time":"2013-08-08T16:49:25Z","timestamp":1375980565000},"page":"1914-1921","source":"Crossref","is-referenced-by-count":14,"title":["Reduced cardiac 123I-metaiodobenzylguanidine uptake in patients with spinocerebellar ataxia type 2: a comparative study with Parkinson\u2019s disease"],"prefix":"10.1007","volume":"40","author":[{"given":"Anna","family":"De Rosa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabina","family":"Pappat\u00e0","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Pellegrino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Fulvia","family":"De Leva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gennaro","family":"Maddaluno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Fiumara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raffaella","family":"Carotenuto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Petretta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Filla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"De Michele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Cuocolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,8,9]]},"reference":[{"key":"2524_CR1","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/BF02984560","volume":"18","author":"J Taki","year":"2004","unstructured":"Taki J, Yoshita M, Yamada M, Tonami N. Significance of 123I-MIBG scintigraphy as a pathophysiological indicator in the assessment of Parkinson\u2019s disease and related disorders: it can be a specific marker for Lewy body disease. Ann Nucl Med. 2004;18:453\u201361.","journal-title":"Ann Nucl Med"},{"key":"2524_CR2","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1093\/brain\/122.8.1437","volume":"122","author":"P Damier","year":"1999","unstructured":"Damier P, Hirsch EC, Agid Y, Graybiel AM. The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson\u2019s disease. Brain. 1999;122:1437\u201348.","journal-title":"Brain"},{"key":"2524_CR3","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1111\/j.1440-1789.2007.00803.x","volume":"27","author":"K Wakabayashi","year":"2007","unstructured":"Wakabayashi K, Tanji K, Mori F, Takahashi H. The Lewy body in Parkinson\u2019s disease: molecules implicated in the formation and degradation of alpha-synuclein aggregates. Neuropathology. 2007;27:494\u2013506.","journal-title":"Neuropathology"},{"key":"2524_CR4","doi-asserted-by":"crossref","first-page":"S6","DOI":"10.1016\/S1353-8020(09)70770-9","volume":"15","author":"EC Wolters","year":"2009","unstructured":"Wolters EC. Non-motor extranigral signs and symptoms in Parkinson\u2019s disease. Parkinsonism Relat Disord. 2009;15:S6\u201312.","journal-title":"Parkinsonism Relat Disord"},{"key":"2524_CR5","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1007\/s00702-011-0598-5","volume":"118","author":"H Oka","year":"2011","unstructured":"Oka H, Toyoda C, Yogo M, Mochio S. Reduced cardiac 123I-MIBG uptake reflects cardiac sympathetic dysfunction in de novo Parkinson\u2019s disease. J Neural Transm. 2011;118:1323\u20137.","journal-title":"J Neural Transm"},{"key":"2524_CR6","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s10286-011-0135-5","volume":"22","author":"G Treglia","year":"2012","unstructured":"Treglia G, Cason E, Stefanelli A, Cocciolillo F, Di Giuda D, Fagioli G, et al. MIBG scintigraphy in differential diagnosis of Parkinsonism: a meta-analysis. Clin Auton Res. 2012;22:43\u201355.","journal-title":"Clin Auton Res"},{"key":"2524_CR7","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1007\/s12035-012-8348-8","volume":"47","author":"JJ Maga\u00f1a","year":"2013","unstructured":"Maga\u00f1a JJ, Vel\u00e1zquez-P\u00e9rez L, Cisneros B. Spinocerebellar ataxia type 2: clinical presentation, molecular mechanisms, and therapeutic perspectives. Mol Neurobiol. 2013;47:90\u2013104.","journal-title":"Mol Neurobiol"},{"key":"2524_CR8","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/S1474-4422(10)70183-6","volume":"9","author":"A Durr","year":"2010","unstructured":"Durr A. Autosomal dominant cerebellar ataxias: polyglutamine expansions and beyond. Lancet Neurol. 2010;9:885\u201394.","journal-title":"Lancet Neurol"},{"key":"2524_CR9","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.jns.2008.07.015","volume":"275","author":"G Joanna De","year":"2008","unstructured":"De Joanna G, De Rosa A, Salvatore E, Castaldo I, De Luca N, Izzo R, et al. Autonomic nervous system abnormalities in spinocerebellar ataxia. J Neurol Sci. 2008;275:60\u20133.","journal-title":"J Neurol Sci"},{"key":"2524_CR10","doi-asserted-by":"crossref","first-page":"156","DOI":"10.5692\/clinicalneurol.50.156","volume":"50","author":"HS Yomono","year":"2010","unstructured":"Yomono HS, Kurisaki H, Hebisawa A, Sakiyama Y, Saito Y, Murayama S. Autopsy case of SCA2 with Parkinsonian phenotype. Rinsho Shinkeigaku. 2010;50:156\u201362.","journal-title":"Rinsho Shinkeigaku"},{"key":"2524_CR11","doi-asserted-by":"crossref","first-page":"S732","DOI":"10.1002\/mds.22499","volume":"24","author":"O Rascol","year":"2009","unstructured":"Rascol O, Schelosky L. 123I-metaiodobenzylguanidine scintigraphy in Parkinson\u2019s disease and related disorders. Mov Disord. 2009;24:S732\u201341.","journal-title":"Mov Disord"},{"key":"2524_CR12","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1212\/01.wnl.0000219042.60538.92","volume":"66","author":"T Schmitz-H\u00fcbsch","year":"2006","unstructured":"Schmitz-H\u00fcbsch T, du Montcel ST, Baliko L, Berciano J, Boesch S, Depondt C, et al. Scale for the assessment and rating of ataxia: development of a new clinical scale. Neurology. 2006;66:1717\u201320.","journal-title":"Neurology"},{"key":"2524_CR13","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1001\/archneur.62.4.630","volume":"62","author":"TH Yeh","year":"2005","unstructured":"Yeh TH, Lu CS, Chou YH, Chong CC, Wu T, Han NH, et al. Autonomic dysfunction in Machado-Joseph disease. Arch Neurol. 2005;62:630\u20136.","journal-title":"Arch Neurol"},{"key":"2524_CR14","first-page":"153","volume-title":"Recent developments in Parkinson\u2019s disease, Vol. 2","author":"S Fahn","year":"1987","unstructured":"Fahn S, Elton RL; Members of the UPDRS Development Committee. The Unified Parkinson\u2019s disease rating scale. In: Fahn S, Marsden CD, Calne DB, Goldstein M, editors. Recent developments in Parkinson\u2019s disease, Vol. 2. Florham Park: Macmillan Healthcare Information; 1987. p. 153\u201363. 293\u2013304."},{"key":"2524_CR15","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1212\/WNL.17.5.427","volume":"17","author":"MM Hoehn","year":"1967","unstructured":"Hoehn MM, Yahr MD. Parkinsonism: onset, progression and mortality. Neurology. 1967;17:427\u201342.","journal-title":"Neurology"},{"key":"2524_CR16","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1007\/s00259-010-1491-4","volume":"37","author":"A Flotats","year":"2010","unstructured":"Flotats A, Carri\u00f3 I, Agostini D, Le Guludec D, Marcassa C, Sch\u00e4fers M, et al.; EANM Cardiovascular Committee; European Council of Nuclear Cardiology. Proposal for standardization of 123I-metaiodobenzylguanidine (MIBG) cardiac sympathetic imaging by the EANM Cardiovascular Committee and the European Council of Nuclear Cardiology. Eur J Nucl Med Mol Imaging. 2010;37:1802\u201312.","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"2524_CR17","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1093\/brain\/118.6.1573","volume":"118","author":"A D\u00fcrr","year":"1995","unstructured":"D\u00fcrr A, Smadja D, Cancel G, Lezin A, Stevanin G, Mikol J, et al. Autosomal dominant cerebellar ataxia type I in Martinique (French West Indies). Clinical and neuropathological analysis of 53 patients from three unrelated SCA2 families. Brain. 1995;118:157\u201381.","journal-title":"Brain"},{"key":"2524_CR18","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1007\/s00401-005-1014-8","volume":"109","author":"K Gierga","year":"2005","unstructured":"Gierga K, B\u00fcrk K, Bauer M, Orozco Diaz G, Auburger G, Schultz C, et al. Involvement of the cranial nerves and their nuclei in spinocerebellar ataxia type 2 (SCA2). Acta Neuropathol. 2005;109:617\u201331.","journal-title":"Acta Neuropathol"},{"key":"2524_CR19","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/BF02278014","volume":"10","author":"T Kazuta","year":"2000","unstructured":"Kazuta T, Hayashi M, Shimizu T, Iwasaki A, Nakamura S, Hirai S. Autonomic dysfunction in Machado-Joseph disease assessed by iodine123-labeled metaiodobenzylguanidine myocardial scintigraphy. Clin Auton Res. 2000;10:111\u20135.","journal-title":"Clin Auton Res"},{"key":"2524_CR20","doi-asserted-by":"crossref","unstructured":"Pellegrino T, Petretta M, De Luca S, Paolillo S, Boemio A, Carotenuto R, et al. Observer reproducibility of results from a low-dose (123)I-metaiodobenzylguanidine cardiac imaging protocol in patients with heart failure. Eur J Nucl Med Mol Imaging. 2013. doi: 10.1007\/s00259-013-2461-4 .","DOI":"10.1007\/s00259-013-2461-4"},{"key":"2524_CR21","first-page":"129","volume":"22","author":"RC Kline","year":"1981","unstructured":"Kline RC, Swanson DP, Wieland DM, Thrall JH, Gross MD, Pitt B, et al. Myocardial imaging in man with I-123 meta-iodobenzylguanidine. J Nucl Med. 1981;22:129\u201332.","journal-title":"J Nucl Med"},{"key":"2524_CR22","first-page":"1625","volume":"28","author":"JC Sisson","year":"1987","unstructured":"Sisson JC, Shapiro B, Meyers L, Mallette S, Mangner TJ, Wieland DM, et al. Metaiodobenzylguanidine to map scintigraphically the adrenergic nervous system in man. J Nucl Med. 1987;28:1625\u201336.","journal-title":"J Nucl Med"},{"key":"2524_CR23","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S1071-3581(95)80023-9","volume":"2","author":"M Estorch","year":"1995","unstructured":"Estorch M, Carri\u00f3 I, Bern\u00e1 L, L\u00f3pez-Pousa J, Torres G. Myocardial iodine-labeled metaiodobenzylguanidine 123 uptake relates to age. J Nucl Cardiol. 1995;2:126\u201332.","journal-title":"J Nucl Cardiol"},{"key":"2524_CR24","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/s12350-010-9239-x","volume":"17","author":"SY Ji","year":"2010","unstructured":"Ji SY, Travin MI. Radionuclide imaging of cardiac autonomic innervation. J Nucl Cardiol. 2010;17:655\u201366.","journal-title":"J Nucl Cardiol"},{"key":"2524_CR25","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/j.1600-0404.2008.01144.x","volume":"120","author":"M Netravathi","year":"2009","unstructured":"Netravathi M, Sathyaprabha TN, Jayalaxmi K, Datta P, Nirmala M, Pal PK. A comparative study of cardiac dysautonomia in autosomal dominant spinocerebellar ataxias and idiopathic sporadic ataxias. Acta Neurol Scand. 2009;120:204\u20139.","journal-title":"Acta Neurol Scand"},{"key":"2524_CR26","doi-asserted-by":"crossref","first-page":"bcr0120113685","DOI":"10.1136\/bcr.01.2011.3685","volume":"2011","author":"M Takao","year":"2011","unstructured":"Takao M, Aoyama M, Ishikawa K, Sakiyama Y, Yomono H, Saito Y, et al. Spinocerebellar ataxia type 2 is associated with Parkinsonism and Lewy body pathology. BMJ Case Rep. 2011;2011:bcr0120113685.","journal-title":"BMJ Case Rep"},{"key":"2524_CR27","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1002\/ana.20054","volume":"553","author":"A Varrone","year":"2004","unstructured":"Varrone A, Salvatore E, De Michele G, Barone P, Sansone V, Pellecchia MT, et al. Reduced striatal [123I]FP-CIT binding in SCA2 patients without parkinsonism. Ann Neurol. 2004;553:426\u201330.","journal-title":"Ann Neurol"},{"key":"2524_CR28","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1007\/s004010050989","volume":"97","author":"R Estrada","year":"1999","unstructured":"Estrada R, Galarraga J, Orozco G, Nodarse A, Auburger G. Spinocerebellar ataxia 2 (SCA2): morphometric analyses in 11 autopsies. Acta Neuropathol. 1999;97:306\u201310.","journal-title":"Acta Neuropathol"},{"key":"2524_CR29","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1212\/WNL.45.4.793","volume":"45","author":"A Filla","year":"1995","unstructured":"Filla A, De Michele G, Banfi S, Santoro L, Perretti A, Cavalcanti F, et al. Has spinocerebellar ataxia type 2 a distinct phenotype? Genetic and clinical study of an Italian family. Neurology. 1995;45:793\u20136.","journal-title":"Neurology"},{"key":"2524_CR30","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1001\/archneur.61.2.257","volume":"61","author":"BP Warrenburg van de","year":"2004","unstructured":"van de Warrenburg BP, Notermans NC, Schelhaas HJ, van Alfen N, Sinke RJ, Knoers NV, et al. Peripheral nerve involvement in spinocerebellar ataxias. Arch Neurol. 2004;61:257\u201361.","journal-title":"Arch Neurol"},{"key":"2524_CR31","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0022-510X(96)00140-2","volume":"142","author":"A Perretti","year":"1996","unstructured":"Perretti A, Santoro L, Lanzillo B, Filla A, De Michele G, Barbieri F, et al. Autosomal dominant cerebellar ataxia type I: multimodal electrophysiological study and comparison between SCA1 and SCA2 patients. J Neurol Sci. 1996;142:45\u201353.","journal-title":"J Neurol Sci"}],"container-title":["European Journal of Nuclear Medicine and Molecular Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00259-013-2524-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00259-013-2524-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00259-013-2524-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T07:51:01Z","timestamp":1715845861000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00259-013-2524-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,9]]},"references-count":31,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["2524"],"URL":"https:\/\/doi.org\/10.1007\/s00259-013-2524-6","relation":{},"ISSN":["1619-7070","1619-7089"],"issn-type":[{"value":"1619-7070","type":"print"},{"value":"1619-7089","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,9]]}}}