{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T09:33:01Z","timestamp":1778923981540,"version":"3.51.4"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2015,12,3]],"date-time":"2015-12-03T00:00:00Z","timestamp":1449100800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Nucl Med Mol Imaging"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1007\/s00259-015-3264-6","type":"journal-article","created":{"date-parts":[[2015,12,3]],"date-time":"2015-12-03T00:01:50Z","timestamp":1449100910000},"page":"1425-1431","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Selective internal radiation therapy in patients with progressive neuroendocrine liver metastases"],"prefix":"10.1007","volume":"43","author":[{"given":"Charlotte Ebeling","family":"Barbier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike","family":"Garske-Rom\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mattias","family":"Sandstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rickard","family":"Nyman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Granberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,12,3]]},"reference":[{"key":"3264_CR1","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/1477-7819-4-35","volume":"4","author":"LM Veenendaal","year":"2006","unstructured":"Veenendaal LM, Borel Rinkes IH, Lips CJ, van Hillegersberg R. Liver metastases of neuroendocrine tumours; early reduction of tumour load to improve life expectancy. World J Surg Oncol. 2006;4:35.","journal-title":"World J Surg Oncol"},{"key":"3264_CR2","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1002\/(SICI)1097-0142(19981201)83:11<2293::AID-CNCR8>3.0.CO;2-E","volume":"83","author":"BK Eriksson","year":"1998","unstructured":"Eriksson BK, Larsson EG, Skogseid BM, L\u00f6fberg A-M, L\u00f6relius L-E, \u00d6berg KE. Liver embolizations of patients with malignant neuroendocrine gastrointestinal tumors. Cancer. 1998;83:2293\u2013301.","journal-title":"Cancer"},{"key":"3264_CR3","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1080\/02841850601080440","volume":"48","author":"D Granberg","year":"2007","unstructured":"Granberg D, Eriksson L-G, Welin S, Kindmark H, Janson ET, Skogseid B, et al. Liver embolization with trisacryl gelatin microspheres (Embosphere) in patients with neuroendocrine tumors. Acta Radiol. 2007;48:180\u20135.","journal-title":"Acta Radiol"},{"key":"3264_CR4","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1007\/s00330-002-1558-0","volume":"13","author":"A Roche","year":"2003","unstructured":"Roche A, Girish BV, de Baere T, Baudin E, Boige V, Elias D, et al. Trans-catheter arterial chemoembolization as first-line treatment for hepatic metastases from endocrine tumors. Eur Radiol. 2003;13:136\u201340.","journal-title":"Eur Radiol"},{"issue":"Suppl 1","key":"3264_CR5","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1159\/000051860","volume":"62","author":"P Ruszniewski","year":"2000","unstructured":"Ruszniewski P, Malka D. Hepatic arterial chemoembolization in the management of advanced digestive endocrine tumors. Digestion. 2000;62 Suppl 1:79\u201383.","journal-title":"Digestion"},{"key":"3264_CR6","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.jvir.2015.02.022","volume":"26","author":"SR Jernigan","year":"2015","unstructured":"Jernigan SR, Osborne JA, Mirek CJ, Buckner G. Selective internal radiation therapy: quantifying distal penetration and distribution of resin and glass microspheres in a surrogate arterial model. J Vasc Interv Radiol. 2015;26:897\u2013904.e2.","journal-title":"J Vasc Interv Radiol"},{"key":"3264_CR7","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1016\/j.ijrobp.2004.09.004","volume":"60","author":"AS Kennedy","year":"2004","unstructured":"Kennedy AS, Nutting C, Coldwell D, Gaiser J, Drachenberg C. Pathologic response and microdosimetry of (90)Y microspheres in man: review of four explanted whole livers. Int J Radiat Oncol Biol Phys. 2004;60:1552\u201363.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"3264_CR8","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1097\/COC.0b013e3181f47923","volume":"35","author":"D Coldwell","year":"2012","unstructured":"Coldwell D, Sangro B, Salem R, Wasan H, Kennedy A. Radioembolization in the treatment of unresectable liver tumors: experience across a range of primary cancers. Am J Clin Oncol. 2012;35:167\u201377.","journal-title":"Am J Clin Oncol"},{"key":"3264_CR9","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1097\/COC.0b013e31815e4557","volume":"31","author":"AS Kennedy","year":"2008","unstructured":"Kennedy AS, Dezarn WA, McNeillie P, Coldwell D, Nutting C, Carter D, et al. Radioembolization for unresectable neuroendocrine hepatic metastases using resin 90Y-microspheres: early results in 148 patients. Am J Clin Oncol. 2008;31:271\u20139.","journal-title":"Am J Clin Oncol"},{"key":"3264_CR10","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1097\/SLA.0b013e3181728a45","volume":"247","author":"TK Rhee","year":"2008","unstructured":"Rhee TK, Lewandowski RJ, Liu DM, Mulcahy MF, Takahashi G, Hansen PD, et al. 90Y Radioembolization for metastatic neuroendocrine liver tumors: preliminary results from a multi-institutional experience. Ann Surg. 2008;247:1029\u201335.","journal-title":"Ann Surg"},{"key":"3264_CR11","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ijrobp.2006.11.060","volume":"68","author":"A Kennedy","year":"2007","unstructured":"Kennedy A, Nag S, Salem R, Murthy R, McEwan AJ, Nutting C, et al. Recommendations for radioembolization of hepatic malignancies using yttrium-90 microsphere brachytherapy: a consensus panel report from the Radioembolization Brachytherapy Oncology Consortium. Int J Radiat Oncol Biol Phys. 2007;68:13\u201323.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"3264_CR12","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1055\/s-0030-1247132","volume":"30","author":"R Lencioni","year":"2010","unstructured":"Lencioni R, Llovet JM. Modified RECIST (mRECIST) assessment for hepatocellular carcinoma. Semin Liver Dis. 2010;30:52\u201360.","journal-title":"Semin Liver Dis"},{"key":"3264_CR13","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1002\/1097-0142(197508)36:2<560::AID-CNCR2820360235>3.0.CO;2-4","volume":"36","author":"JD Godwin 2nd","year":"1975","unstructured":"Godwin 2nd JD. Carcinoid tumors. An analysis of 2,837 cases. Cancer. 1975;36:560\u20139.","journal-title":"Cancer"},{"key":"3264_CR14","first-page":"48","volume":"111","author":"O Soreide","year":"1992","unstructured":"Soreide O, Berstad T, Bakka A, Schrumpf E, Hanssen LE, Engh V, et al. Surgical treatment as a principle in patients with advanced abdominal carcinoid tumors. Surgery. 1992;111:48\u201354.","journal-title":"Surgery"},{"key":"3264_CR15","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1001\/archsurg.141.10.1000","volume":"141","author":"S Musunuru","year":"2006","unstructured":"Musunuru S, Chen H, Rajpal S, Stephani N, McDermott JC, Holen K, et al. Metastatic neuroendocrine hepatic tumors: resection improves survival. Arch Surg. 2006;141:1000\u20134. Discussion 1005.","journal-title":"Arch Surg"},{"key":"3264_CR16","doi-asserted-by":"crossref","unstructured":"Chen H, Hardacre JM, Uzar A, Cameron JL, Choti MA. Isolated liver metastases from neuroendocrine tumors: does resection prolong survival? J Am Coll Surg. 1998;187:88\u201392. Discussion 92\u20133.","DOI":"10.1016\/S1072-7515(98)00099-4"},{"key":"3264_CR17","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.2214\/ajr.175.6.1751619","volume":"175","author":"T Baere de","year":"2000","unstructured":"de Baere T, Elias D, Dromain C, Din MG, Kuoch V, Ducreux M, et al. Radiofrequency ablation of 100 hepatic metastases with a mean follow-up of more than 1 year. AJR Am J Roentgenol. 2000;175:1619\u201325.","journal-title":"AJR Am J Roentgenol"},{"key":"3264_CR18","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1002\/cncr.21389","volume":"104","author":"S Gupta","year":"2005","unstructured":"Gupta S, Johnson MM, Murthy R, Ahrar K, Wallace MJ, Madoff DC, et al. Hepatic arterial embolization and chemoembolization for the treatment of patients with metastatic neuroendocrine tumors. Cancer. 2005;104:1590\u2013602.","journal-title":"Cancer"},{"key":"3264_CR19","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1177\/107327480601300110","volume":"13","author":"JR Strosberg","year":"2006","unstructured":"Strosberg JR, Choi J, Cantor AB, Kvols LK. Selective hepatic artery embolization for treatment of patients with metastatic carcinoid and pancreatic endocrine tumors. Cancer Control. 2006;13:72\u20138.","journal-title":"Cancer Control"},{"key":"3264_CR20","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/s11605-007-0089-z","volume":"11","author":"M Bloomston","year":"2007","unstructured":"Bloomston M, Al-Saif O, Klemanski D, Pinzone JJ, Martin EW, Palmer B, et al. Hepatic artery chemoembolization in 122 patients with metastatic carcinoid tumor: lessons learned. J Gastrointest Surg. 2007;11:264\u201371.","journal-title":"J Gastrointest Surg"},{"key":"3264_CR21","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.surg.2008.08.037","volume":"144","author":"D Christante","year":"2008","unstructured":"Christante D, Pommier S, Givi B, Pommier RF. Hepatic artery chemoinfusion with chemoembolization for neuroendocrine cancer with progressive hepatic metastases despite octreotide therapy. Surgery. 2008;144:885\u201393. Discussion 893\u2013894.","journal-title":"Surgery"},{"issue":"Suppl 1","key":"3264_CR22","doi-asserted-by":"crossref","first-page":"S286","DOI":"10.1007\/s12032-010-9750-6","volume":"28","author":"XD Dong","year":"2011","unstructured":"Dong XD, Carr BI. Hepatic artery chemoembolization for the treatment of liver metastases from neuroendocrine tumors: a long-term follow-up in 123 patients. Med Oncol. 2011;28 Suppl 1:S286\u201390.","journal-title":"Med Oncol"},{"key":"3264_CR23","doi-asserted-by":"crossref","first-page":"941","DOI":"10.2214\/AJR.08.1879","volume":"193","author":"TJ Vogl","year":"2009","unstructured":"Vogl TJ, Gruber T, Naguib NN, Hammerstingl R, Nour-Eldin NE. Liver metastases of neuroendocrine tumors: treatment with hepatic transarterial chemotherapy using two therapeutic protocols. AJR Am J Roentgenol. 2009;193:941\u20137.","journal-title":"AJR Am J Roentgenol"},{"key":"3264_CR24","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1245\/s10434-012-2786-4","volume":"20","author":"D Arrese","year":"2013","unstructured":"Arrese D, McNally ME, Chokshi R, Feria-Arias E, Schmidt C, Klemanski D, et al. Extrahepatic disease should not preclude transarterial chemoembolization for metastatic neuroendocrine carcinoma. Ann Surg Oncol. 2013;20:1114\u201320.","journal-title":"Ann Surg Oncol"},{"key":"3264_CR25","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1002\/bjs.6931","volume":"97","author":"CQ Cao","year":"2010","unstructured":"Cao CQ, Yan TD, Bester L, Liauw W, Morris DL. Radioembolization with yttrium microspheres for neuroendocrine tumour liver metastases. Br J Surg. 2010;97:537\u201343.","journal-title":"Br J Surg"},{"key":"3264_CR26","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1002\/cncr.23685","volume":"113","author":"J King","year":"2008","unstructured":"King J, Quinn R, Glenn DM, Janssen J, Tong D, Liaw W, et al. Radioembolization with selective internal radiation microspheres for neuroendocrine liver metastases. Cancer. 2008;113:921\u20139.","journal-title":"Cancer"},{"key":"3264_CR27","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/j.ijrobp.2011.07.041","volume":"83","author":"K Memon","year":"2012","unstructured":"Memon K, Lewandowski RJ, Mulcahy MF, Riaz A, Ryu RK, Sato KT, et al. Radioembolization for neuroendocrine liver metastases: safety, imaging, and long-term outcomes. Int J Radiat Oncol Biol Phys. 2012;83:887\u201394.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"3264_CR28","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1007\/s00270-011-0248-1","volume":"35","author":"PM Paprottka","year":"2012","unstructured":"Paprottka PM, Hoffmann RT, Haug A, Sommer WH, Raessler F, Trumm CG, et al. Radioembolization of symptomatic, unresectable neuroendocrine hepatic metastases using yttrium-90 microspheres. Cardiovasc Intervent Radiol. 2012;35:334\u201342.","journal-title":"Cardiovasc Intervent Radiol"},{"key":"3264_CR29","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1097\/SLA.0b013e3181d3d24a","volume":"251","author":"A Saxena","year":"2010","unstructured":"Saxena A, Chua TC, Bester L, Kokandi A, Morris DL. Factors predicting response and survival after yttrium-90 radioembolization of unresectable neuroendocrine tumor liver metastases: a critical appraisal of 48 cases. Ann Surg. 2010;251:910\u20136.","journal-title":"Ann Surg"},{"key":"3264_CR30","doi-asserted-by":"crossref","first-page":"3122","DOI":"10.1016\/j.ejca.2013.05.012","volume":"49","author":"AB Benson 3rd","year":"2013","unstructured":"Benson 3rd AB, Geschwind JF, Mulcahy MF, Rilling W, Siskin G, Wiseman G, et al. Radioembolisation for liver metastases: results from a prospective 151 patient multi-institutional phase II study. Eur J Cancer. 2013;49:3122\u201330.","journal-title":"Eur J Cancer"},{"key":"3264_CR31","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1097\/MPA.0b013e31825f4087","volume":"42","author":"J Ozao-Choy","year":"2013","unstructured":"Ozao-Choy J, Friedman ML, Kim AS, Wachsman A, Wolin EM, Yu R, et al. Radioembolization for treatment of liver metastases from neuroendocrine tumors: correlation with imaging and biomarkers. Pancreas. 2013;42:358\u201360.","journal-title":"Pancreas"},{"key":"3264_CR32","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/hpb.12326","volume":"17","author":"A Kennedy","year":"2015","unstructured":"Kennedy A, Bester L, Salem R, Sharma RA, Parks RW, Ruszniewski P. Role of hepatic intra-arterial therapies in metastatic neuroendocrine tumours (NET): guidelines from the NET-Liver-Metastases Consensus Conference. HPB (Oxford). 2015;17:29\u201337.","journal-title":"HPB (Oxford)"},{"key":"3264_CR33","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1111\/liv.12750","volume":"35","author":"FT Kolligs","year":"2015","unstructured":"Kolligs FT, Bilbao JI, Jakobs T, I\u00f1arrairaegui M, Nagel JM, Rodriguez M, et al. Pilot randomized trial of selective internal radiation therapy vs. chemoembolization in unresectable hepatocellular carcinoma. Liver Int. 2015;35:1715\u201321.","journal-title":"Liver Int"},{"key":"3264_CR34","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.crad.2013.09.009","volume":"69","author":"JM Theysohn","year":"2014","unstructured":"Theysohn JM, Ertle J, Muller S, Schlaak JF, Nensa F, Sipilae S, et al. Hepatic volume changes after lobar selective internal radiation therapy (SIRT) of hepatocellular carcinoma. Clin Radiol. 2014;69:172\u20138.","journal-title":"Clin Radiol"}],"container-title":["European Journal of Nuclear Medicine and Molecular Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00259-015-3264-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00259-015-3264-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00259-015-3264-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,12]],"date-time":"2020-09-12T05:33:45Z","timestamp":1599888825000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00259-015-3264-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,3]]},"references-count":34,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["3264"],"URL":"https:\/\/doi.org\/10.1007\/s00259-015-3264-6","relation":{},"ISSN":["1619-7070","1619-7089"],"issn-type":[{"value":"1619-7070","type":"print"},{"value":"1619-7089","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,3]]}}}