{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T02:31:54Z","timestamp":1793759514366,"version":"4.6.1"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2018,8,9]],"date-time":"2018-08-09T00:00:00Z","timestamp":1533772800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Nucl Med Mol Imaging"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1007\/s00259-018-4123-z","type":"journal-article","created":{"date-parts":[[2018,8,9]],"date-time":"2018-08-09T13:05:18Z","timestamp":1533819918000},"page":"751-765","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":210,"title":["Diagnostic performance of choline PET for detection of hyperfunctioning parathyroid glands in hyperparathyroidism: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9808-780X","authenticated-orcid":false,"given":"Giorgio","family":"Treglia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnoldo","family":"Piccardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessio","family":"Imperiale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Strobel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp A.","family":"Kaufmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John O.","family":"Prior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Giovanella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,8,9]]},"reference":[{"issue":"10116","key":"4123_CR1","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/S0140-6736(17)31430-7","volume":"391","author":"JP Bilezikian","year":"2018","unstructured":"Bilezikian JP, Bandeira L, Khan A, Cusano NE. Hyperparathyroidism. Lancet. 2018;391(10116):168\u201378.","journal-title":"Lancet"},{"issue":"2","key":"4123_CR2","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1038\/nrendo.2017.104","volume":"14","author":"MD Walker","year":"2018","unstructured":"Walker MD, Silverberg SJ. Primary hyperparathyroidism. Nat Rev Endocrinol. 2018;14(2):115\u201325.","journal-title":"Nat Rev Endocrinol"},{"issue":"1","key":"4123_CR3","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1007\/s11154-017-9421-4","volume":"18","author":"MR Portillo","year":"2017","unstructured":"Portillo MR, Rodr\u00edguez-Ortiz ME. Secondary hyperparthyroidism: pathogenesis, diagnosis, preventive and therapeutic strategies. Rev Endocr Metab Disord. 2017;18(1):79\u201395.","journal-title":"Rev Endocr Metab Disord"},{"issue":"2","key":"4123_CR4","first-page":"e158","volume":"168","author":"G Cocchiara","year":"2017","unstructured":"Cocchiara G, Fazzotta S, Palumbo VD, Damiano G, Cajozzo M, Maione C, et al. The medical and surgical treatment in secondary and tertiary hyperparathyroidism. Review. Clin Ter. 2017;168(2):e158\u201367.","journal-title":"Clin Ter"},{"key":"4123_CR5","doi-asserted-by":"publisher","first-page":"3595","DOI":"10.1210\/jc.2014-2000","volume":"99","author":"R Udelsman","year":"2014","unstructured":"Udelsman R, \u00c5kerstr\u00f6m G, Biagini C, Duh QY, Miccoli P, Niederle B, et al. The surgical management of asymptomatic primary hyperparathyroidism: proceedings of the fourth international workshop. J Clin Endocrinol Metab. 2014;99:3595\u2013606.","journal-title":"J Clin Endocrinol Metab"},{"issue":"9","key":"4123_CR6","doi-asserted-by":"publisher","first-page":"878","DOI":"10.1001\/jamasurg.2017.1721","volume":"152","author":"AE Stephen","year":"2017","unstructured":"Stephen AE, Mannstadt M, Hodin RA. Indications for surgical management of hyperparathyroidism: a review. JAMA Surg. 2017;152(9):878\u201382.","journal-title":"JAMA Surg"},{"issue":"2","key":"4123_CR7","doi-asserted-by":"crossref","first-page":"133","DOI":"10.23736\/S0391-1977.17.02685-2","volume":"43","author":"G Treglia","year":"2018","unstructured":"Treglia G, Trimboli P, Huellner M, Giovanella L. Imaging in primary hyperparathyroidism: focus on the evidence-based diagnostic performance of different methods. Minerva Endocrinol. 2018;43(2):133\u201343.","journal-title":"Minerva Endocrinol"},{"issue":"1","key":"4123_CR8","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.carj.2016.07.004","volume":"68","author":"S Liddy","year":"2017","unstructured":"Liddy S, Worsley D, Torreggiani W, Feeney J. Preoperative imaging in primary hyperparathyroidism: literature review and recommendations. Can Assoc Radiol J. 2017;68(1):47\u201355.","journal-title":"Can Assoc Radiol J"},{"issue":"1","key":"4123_CR9","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.mric.2017.08.009","volume":"26","author":"SJ Kuzminski","year":"2018","unstructured":"Kuzminski SJ, Sosa JA, Hoang JK. Update in parathyroid imaging. Magn Reson Imaging Clin N Am. 2018;26(1):151\u201366.","journal-title":"Magn Reson Imaging Clin N Am"},{"issue":"7","key":"4123_CR10","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1007\/s00423-016-1425-0","volume":"401","author":"WP Kluijfhout","year":"2016","unstructured":"Kluijfhout WP, Pasternak JD, Drake FT, Beninato T, Gosnell JE, Shen WT, et al. Use of PET tracers for parathyroid localization: a systematic review and meta-analysis. Langenbeck\u2019s Arch Surg. 2016;401(7):925\u201335.","journal-title":"Langenbeck\u2019s Arch Surg"},{"issue":"1","key":"4123_CR11","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1007\/s12020-012-9746-4","volume":"43","author":"C Caldarella","year":"2013","unstructured":"Caldarella C, Treglia G, Isgr\u00f2 MA, Giordano A. Diagnostic performance of positron emission tomography using 11C-methionine in patients with suspected parathyroid adenoma: a meta-analysis. Endocrine. 2013;43(1):78\u201383.","journal-title":"Endocrine"},{"issue":"4","key":"4123_CR12","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1007\/s00259-017-3920-0","volume":"45","author":"A Imperiale","year":"2018","unstructured":"Imperiale A, Ta\u00efeb D, Hindi\u00e9 E. (18)F-Fluorocholine PET\/CT as a second line nuclear imaging technique before surgery for primary hyperparathyroidism. Eur J Nucl Med Mol Imaging. 2018;45(4):654\u20137.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"2","key":"4123_CR13","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/j.ando.2015.03.026","volume":"76","author":"JO Prior","year":"2015","unstructured":"Prior JO. New scintigraphic methods for parathyroid imaging. Ann Endocrinol. 2015;76(2):145\u20137.","journal-title":"Ann Endocrinol"},{"issue":"6","key":"4123_CR14","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1007\/s12149-012-0602-7","volume":"26","author":"G Treglia","year":"2012","unstructured":"Treglia G, Giovannini E, Di Franco D, Calcagni ML, Rufini V, Picchio M, et al. The role of positron emission tomography using carbon-11 and fluorine-18 choline in tumors other than prostate cancer: a systematic review. Ann Nucl Med. 2012;26(6):451\u201361.","journal-title":"Ann Nucl Med"},{"key":"4123_CR15","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1016\/j.jclinepi.2009.06.006","volume":"62","author":"A Liberati","year":"2009","unstructured":"Liberati A, Altman DG, Tetzlaff J, Mulrow C, G\u00f8tzsche PC, Ioannidis JP, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol. 2009;62:e1\u201334.","journal-title":"J Clin Epidemiol"},{"key":"4123_CR16","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/s40336-016-0219-2","volume":"5","author":"R Sadeghi","year":"2017","unstructured":"Sadeghi R, Treglia G. Systematic reviews and meta-analyses of diagnostic studies: a practical guideline. Clin Transl Imaging. 2017;5:83\u20137.","journal-title":"Clin Transl Imaging"},{"issue":"8","key":"4123_CR17","doi-asserted-by":"publisher","first-page":"529","DOI":"10.7326\/0003-4819-155-8-201110180-00009","volume":"155","author":"PF Whiting","year":"2011","unstructured":"Whiting PF, Rutjes AW, Westwood ME, Mallett S, Deeks JJ, Reitsma JB, et al. Bossuyt PM; QUADAS-2 group. QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med. 2011;155(8):529\u201336.","journal-title":"Ann Intern Med"},{"issue":"11","key":"4123_CR18","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1002\/sim.1186","volume":"21","author":"JP Higgins","year":"2002","unstructured":"Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21(11):1539\u201358.","journal-title":"Stat Med"},{"issue":"20","key":"4123_CR19","doi-asserted-by":"publisher","first-page":"3443","DOI":"10.1002\/sim.2380","volume":"25","author":"RM Harbord","year":"2006","unstructured":"Harbord RM, Egger M, Sterne JA. A modified test for small-study effects in meta-analyses of controlled trials with binary endpoints. Stat Med. 2006;25(20):3443\u201357.","journal-title":"Stat Med"},{"issue":"7","key":"4123_CR20","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1097\/RLU.0000000000002132","volume":"43","author":"D Morland","year":"2018","unstructured":"Morland D, Richard C, Godard F, Deguelte S, Delemer B. Temporal uptake patterns of 18F-Fluorocholine among hyperfunctioning parathyroid glands. Clin Nucl Med. 2018;43(7):504\u20135.","journal-title":"Clin Nucl Med"},{"key":"4123_CR21","doi-asserted-by":"publisher","unstructured":"Alharbi AA, Alshehri FM, Albatly AA, Sah BR, Schmid C, Huber GF, et al. [(18)F]Fluorocholine uptake of parathyroid adenoma is correlated with parathyroid hormone level. Mol Imaging Biol. 2018; https:\/\/doi.org\/10.1007\/s11307-018-1179-x .","DOI":"10.1007\/s11307-018-1179-x"},{"key":"4123_CR22","doi-asserted-by":"publisher","unstructured":"Grimaldi S, Young J, Kamenicky P, Hartl D, Terroir M, Leboulleux S, et al. Challenging pre-surgical localization of hyperfunctioning parathyroid glands in primary hyperparathyroidism: the added value of (18)F-Fluorocholine PET\/CT. Eur J Nucl Med Mol Imaging. 2018; https:\/\/doi.org\/10.1007\/s00259-018-4018-z .","DOI":"10.1007\/s00259-018-4018-z"},{"key":"4123_CR23","doi-asserted-by":"publisher","unstructured":"Beheshti M, Hehenwarter L, Paymani Z, Rendl G, Imamovic L, Rettenbacher R, et al. (18)F-Fluorocholine PET\/CT in the assessment of primary hyperparathyroidism compared with (99m)Tc-MIBI or (99m)Tc-tetrofosmin SPECT\/CT: a prospective dual-centre study in 100 patients. Eur J Nucl Med Mol Imaging. 2018; https:\/\/doi.org\/10.1007\/s00259-018-3980-9 .","DOI":"10.1007\/s00259-018-3980-9"},{"key":"4123_CR24","doi-asserted-by":"publisher","first-page":"380","DOI":"10.3389\/fendo.2017.00380","volume":"8","author":"S Fischli","year":"2018","unstructured":"Fischli S, Suter-Widmer I, Nguyen BT, M\u00fcller W, Metzger J, Strobel K, et al. The significance of 18F-Fluorocholine-PET\/CT as localizing imaging technique in patients with primary hyperparathyroidism and negative conventional imaging. Front Endocrinol. 2018;8:380. https:\/\/doi.org\/10.3389\/fendo.2017.00380 .","journal-title":"Front Endocrinol"},{"issue":"6","key":"4123_CR25","doi-asserted-by":"publisher","first-page":"2700","DOI":"10.1007\/s00330-017-5190-4","volume":"28","author":"GF Huber","year":"2018","unstructured":"Huber GF, H\u00fcllner M, Schmid C, Brunner A, Sah B, Vetter D, et al. Benefit of (18)F-fluorocholine PET imaging in parathyroid surgery. Eur Radiol. 2018;28(6):2700\u20137.","journal-title":"Eur Radiol"},{"issue":"2","key":"4123_CR26","doi-asserted-by":"publisher","first-page":"418","DOI":"10.2214\/AJR.17.18312","volume":"210","author":"A Parvinian","year":"2018","unstructured":"Parvinian A, Martin-Macintosh EL, Goenka AH, Durski JM, Mullan BP, Kemp BJ, et al. (11)C-choline PET\/CT for detection and localization of parathyroid adenomas. AJR Am J Roentgenol. 2018;210(2):418\u201322.","journal-title":"AJR Am J Roentgenol"},{"issue":"4","key":"4123_CR27","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1007\/s00259-017-3911-1","volume":"45","author":"E Quak","year":"2018","unstructured":"Quak E, Blanchard D, Houdu B, Le Roux Y, Ciappuccini R, Lireux B, et al. F18-choline PET\/CT guided surgery in primary hyperparathyroidism when ultrasound and MIBI SPECT\/CT are negative or inconclusive: the APACH1 study. Eur J Nucl Med Mol Imaging. 2018;45(4):658\u201366.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"1","key":"4123_CR28","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1088\/1361-6498\/aaa86f","volume":"38","author":"S Rep","year":"2018","unstructured":"Rep S, Hocevar M, Vaupotic J, Zdesar U, Zaletel K, Lezaic L. (18)F-choline PET\/CT for parathyroid scintigraphy: significantly lower radiation exposure of patients in comparison to conventional nuclear medicine imaging approaches. J Radiol Prot. 2018;38(1):343\u201356.","journal-title":"J Radiol Prot"},{"issue":"1","key":"4123_CR29","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.ejso.2016.09.016","volume":"43","author":"M Hocevar","year":"2017","unstructured":"Hocevar M, Lezaic L, Rep S, Zaletel K, Kocjan T, Sever MJ, et al. Focused parathyroidectomy without intraoperative parathormone testing is safe after pre-operative localization with (18)F-Fluorocholine PET\/CT. Eur J Surg Oncol. 2017;43(1):133\u20137.","journal-title":"Eur J Surg Oncol"},{"issue":"2","key":"4123_CR30","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1148\/radiol.2016160768","volume":"284","author":"WP Kluijfhout","year":"2017","unstructured":"Kluijfhout WP, Pasternak JD, Gosnell JE, Shen WT, Duh QY, Vriens MR, et al. (18)F Fluorocholine PET\/MR imaging in patients with primary hyperparathyroidism and inconclusive conventional imaging: a prospective pilot study. Radiology. 2017;284(2):460\u20137.","journal-title":"Radiology"},{"issue":"3","key":"4123_CR31","doi-asserted-by":"publisher","first-page":"399","DOI":"10.4103\/ijem.IJEM_536_16","volume":"21","author":"SK Taywade","year":"2017","unstructured":"Taywade SK, Damle NA, Behera A, Devasenathipathy K, Bal C, Tripathi M, et al. Comparison of 18F-Fluorocholine positron emission tomography\/computed tomography and four-dimensional computed tomography in the preoperative localization of parathyroid adenomas-initial results. Indian J Endocrinol Metab. 2017;21(3):399\u2013403.","journal-title":"Indian J Endocrinol Metab"},{"issue":"12","key":"4123_CR32","doi-asserted-by":"publisher","first-page":"e491","DOI":"10.1097\/RLU.0000000000001845","volume":"42","author":"N Thanseer","year":"2017","unstructured":"Thanseer N, Bhadada SK, Sood A, Mittal BR, Behera A, Gorla AKR, et al. Comparative effectiveness of ultrasonography, 99mTc-Sestamibi, and 18F-Fluorocholine PET\/CT in detecting parathyroid adenomas in patients with primary hyperparathyroidism. Clin Nucl Med. 2017;42(12):e491\u20137.","journal-title":"Clin Nucl Med"},{"issue":"12","key":"4123_CR33","doi-asserted-by":"publisher","first-page":"1246","DOI":"10.1097\/MNM.0000000000000595","volume":"37","author":"WP Kluijfhout","year":"2016","unstructured":"Kluijfhout WP, Vorselaars WM, van den Berk SA, Vriens MR, Borel Rinkes IH, Valk GD, et al. Fluorine-18 fluorocholine PET-CT localizes hyperparathyroidism in patients with inconclusive conventional imaging: a multicenter study from the Netherlands. Nucl Med Commun. 2016;37(12):1246\u201352.","journal-title":"Nucl Med Commun"},{"issue":"9","key":"4123_CR34","doi-asserted-by":"publisher","first-page":"1745","DOI":"10.1016\/j.ejrad.2015.05.024","volume":"84","author":"WP Kluijfhout","year":"2015","unstructured":"Kluijfhout WP, Vorselaars WM, Vriens MR, Borel Rinkes IH, Valk GD, de Keizer B. Enabling minimal invasive parathyroidectomy for patients with primary hyperparathyroidism using Tc-99m-sestamibi SPECT-CT, ultrasound and first results of (18)F-fluorocholine PET-CT. Eur J Radiol. 2015;84(9):1745\u201351.","journal-title":"Eur J Radiol"},{"issue":"41","key":"4123_CR35","doi-asserted-by":"publisher","first-page":"e1701","DOI":"10.1097\/MD.0000000000001701","volume":"94","author":"L Michaud","year":"2015","unstructured":"Michaud L, Balogova S, Burgess A, Ohnona J, Huchet V, Kerrou K, et al. A pilot comparison of 18F-fluorocholine PET\/CT, ultrasonography and 123I\/99mTc-sestaMIBI dual-phase dual-isotope scintigraphy in the preoperative localization of Hyperfunctioning parathyroid glands in primary or secondary hyperparathyroidism: influence of thyroid anomalies. Medicine (Baltimore). 2015;94(41):e1701.","journal-title":"Medicine (Baltimore)"},{"issue":"4","key":"4123_CR36","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1515\/raon-2015-0016","volume":"49","author":"S Rep","year":"2015","unstructured":"Rep S, Lezaic L, Kocjan T, Pfeifer M, Sever MJ, Simoncic U, et al. Optimal scan time for evaluation of parathyroid adenoma with [(18)F]-fluorocholine PET\/CT. Radiol Oncol. 2015;49(4):327\u201333.","journal-title":"Radiol Oncol"},{"issue":"11","key":"4123_CR37","doi-asserted-by":"publisher","first-page":"2083","DOI":"10.1007\/s00259-014-2837-0","volume":"41","author":"L Lezaic","year":"2014","unstructured":"Lezaic L, Rep S, Sever MJ, Kocjan T, Hocevar M, Fettich J. 18F-Fluorocholine PET\/CT for localization of hyperfunctioning parathyroid tissue in primary hyperparathyroidism: a pilot study. Eur J Nucl Med Mol Imaging. 2014;41(11):2083\u20139.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"12","key":"4123_CR38","doi-asserted-by":"publisher","first-page":"4531","DOI":"10.1210\/jc.2014-2821","volume":"99","author":"L Michaud","year":"2014","unstructured":"Michaud L, Burgess A, Huchet V, Lef\u00e8vre M, Tassart M, Ohnona J, et al. Is 18F-fluorocholine-positron emission tomography\/computerized tomography a new imaging tool for detecting hyperfunctioning parathyroid glands in primary or secondary hyperparathyroidism? J Clin Endocrinol Metab. 2014;99(12):4531\u20136.","journal-title":"J Clin Endocrinol Metab"},{"issue":"12","key":"4123_CR39","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1097\/RLU.0000000000000607","volume":"39","author":"M Orevi","year":"2014","unstructured":"Orevi M, Freedman N, Mishani E, Bocher M, Jacobson O, Krausz Y. Localization of parathyroid adenoma by 11C-choline PET\/CT: preliminary results. Clin Nucl Med. 2014;39(12):1033\u20138.","journal-title":"Clin Nucl Med"},{"issue":"Suppl 1","key":"4123_CR40","doi-asserted-by":"publisher","first-page":"E2159","DOI":"10.1002\/hed.24027","volume":"38","author":"G Treglia","year":"2016","unstructured":"Treglia G, Sadeghi R, Schalin-J\u00e4ntti C, Caldarella C, Ceriani L, Giovanella L, et al. Detection rate of (99m) Tc-MIBI single photon emission computed tomography (SPECT)\/CT in preoperative planning for patients with primary hyperparathyroidism: a meta-analysis. Head Neck. 2016;38(Suppl 1):E2159\u201372.","journal-title":"Head Neck"},{"key":"4123_CR41","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.ejrad.2017.01.004","volume":"88","author":"WP Kluijfhout","year":"2017","unstructured":"Kluijfhout WP, Pasternak JD, Beninato T, Drake FT, Gosnell JE, Shen WT, et al. Diagnostic performance of computed tomography for parathyroid adenoma localization; a systematic review and meta-analysis. Eur J Radiol. 2017;88:117\u201328.","journal-title":"Eur J Radiol"}],"container-title":["European Journal of Nuclear Medicine and Molecular Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00259-018-4123-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00259-018-4123-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00259-018-4123-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,28]],"date-time":"2022-08-28T20:10:29Z","timestamp":1661717429000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00259-018-4123-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,9]]},"references-count":41,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["4123"],"URL":"https:\/\/doi.org\/10.1007\/s00259-018-4123-z","relation":{},"ISSN":["1619-7070","1619-7089"],"issn-type":[{"value":"1619-7070","type":"print"},{"value":"1619-7089","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,9]]},"assertion":[{"value":"6 June 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 August 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 August 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no financial or non-financial competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}