{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T02:50:55Z","timestamp":1791859855625,"version":"4.3.4"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:00:00Z","timestamp":1732665600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:00:00Z","timestamp":1732665600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"the Ministry of Industry and Information Technology","award":["CEIEC-2022-ZM02-0219"],"award-info":[{"award-number":["CEIEC-2022-ZM02-0219"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Nucl Med Mol Imaging"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1007\/s00259-024-06986-2","type":"journal-article","created":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:25:13Z","timestamp":1732667113000},"page":"1083-1094","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Comparison of [18F]FAPI-42 and [18F]FDG PET\/CT in the evaluation of systemic vasculitis"],"prefix":"10.1007","volume":"52","author":[{"given":"Kaixiang","family":"Zhong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiming","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linling","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenliang","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youcai","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Ke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofeng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongxia","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunli","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1997-5687","authenticated-orcid":false,"given":"Xinlu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,27]]},"reference":[{"key":"6986_CR1","doi-asserted-by":"publisher","unstructured":"Jennette JC, Falk RJ, Bacon PA, Basu N, Cid MC, Ferrario F et al. 2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides. Arthritis Rheum. 2013;65:1\u201311. https:\/\/doi.org\/10.1002\/art.37715","DOI":"10.1002\/art.37715"},{"key":"6986_CR2","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1136\/annrheumdis-2017-212649","volume":"77","author":"C Dejaco","year":"2018","unstructured":"Dejaco C, Ramiro S, Duftner C, Besson FL, Bley TA, Blockmans D, et al. EULAR recommendations for the use of imaging in large vessel vasculitis in clinical practice. Ann Rheum Dis. 2018;77:636\u201343. https:\/\/doi.org\/10.1136\/annrheumdis-2017-212649","journal-title":"Ann Rheum Dis"},{"issue":"Suppl 103","key":"6986_CR3","first-page":"189","volume":"35","author":"H Direskeneli","year":"2017","unstructured":"Direskeneli H. Clinical assessment in Takayasu\u2019s arteritis: major challenges and controversies. Clin Exp Rheumatol. 2017;35(Suppl 103):189\u201393.","journal-title":"Clin Exp Rheumatol"},{"key":"6986_CR4","doi-asserted-by":"publisher","unstructured":"Slart R, Writing g, Reviewer g, Members of EC, Members of EI, Inflammation, et al. FDG-PET\/CT(A) imaging in large vessel vasculitis and polymyalgia rheumatica: joint procedural recommendation of the EANM, SNMMI, and the PET Interest Group (PIG), and endorsed by the ASNC. Eur J Nucl Med Mol Imaging. 2018;45:1250-69. https:\/\/doi.org\/10.1007\/s00259-018-3973-8","DOI":"10.1007\/s00259-018-3973-8"},{"key":"6986_CR5","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1007\/s11886-019-1122-z","volume":"21","author":"M Pelletier-Galarneau","year":"2019","unstructured":"Pelletier-Galarneau M, Ruddy TD. PET\/CT for diagnosis and management of large-vessel vasculitis. Curr Cardiol Rep. 2019;21:34. https:\/\/doi.org\/10.1007\/s11886-019-1122-z","journal-title":"Curr Cardiol Rep"},{"key":"6986_CR6","doi-asserted-by":"publisher","first-page":"1499","DOI":"10.1007\/s10067-021-06039-1","volume":"41","author":"Z Chen","year":"2022","unstructured":"Chen Z, Zhao Y, Wang Q, Li Y, Li H, Zhou Y. Imaging features of (18)F-FDG PET\/CT in different types of systemic vasculitis. Clin Rheumatol. 2022;41:1499\u2013509. https:\/\/doi.org\/10.1007\/s10067-021-06039-1","journal-title":"Clin Rheumatol"},{"key":"6986_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1148\/radiol.2017162495","volume":"283","author":"V Dilsizian","year":"2017","unstructured":"Dilsizian V, Jadvar H. Science to practice: does FDG differentiate morphologically unstable from stable atherosclerotic plaque? Radiology. 2017;283:1\u20133. https:\/\/doi.org\/10.1148\/radiol.2017162495","journal-title":"Radiology"},{"key":"6986_CR8","doi-asserted-by":"publisher","first-page":"1193","DOI":"10.1002\/art.24416","volume":"60","author":"L Arnaud","year":"2009","unstructured":"Arnaud L, Haroche J, Malek Z, Archambaud F, Gambotti L, Grimon G, et al. Is (18)F-fluorodeoxyglucose positron emission tomography scanning a reliable way to assess disease activity in Takayasu arteritis? Arthritis Rheum. 2009;60:1193\u2013200. https:\/\/doi.org\/10.1002\/art.24416","journal-title":"Arthritis Rheum"},{"key":"6986_CR9","doi-asserted-by":"publisher","first-page":"801","DOI":"10.2967\/jnumed.119.227967","volume":"60","author":"C Kratochwil","year":"2019","unstructured":"Kratochwil C, Flechsig P, Lindner T, Abderrahim L, Altmann A, Mier W, et al. (68)Ga-FAPI PET\/CT: tracer uptake in 28 different kinds of cancer. J Nucl Med. 2019;60:801\u20135. https:\/\/doi.org\/10.2967\/jnumed.119.227967","journal-title":"J Nucl Med"},{"key":"6986_CR10","doi-asserted-by":"publisher","first-page":"1848","DOI":"10.1007\/s00259-023-06179-3","volume":"50","author":"G Treglia","year":"2023","unstructured":"Treglia G, Albano D. FAPI PET\/CT in infectious, inflammatory, and rheumatological diseases: watch it like a hawk or one swallow does not make a summer? Eur J Nucl Med Mol Imaging. 2023;50:1848\u201350. https:\/\/doi.org\/10.1007\/s00259-023-06179-3","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"6986_CR11","doi-asserted-by":"publisher","first-page":"e220749","DOI":"10.1148\/radiol.220749","volume":"306","author":"Y Mori","year":"2023","unstructured":"Mori Y, Dendl K, Cardinale J, Kratochwil C, Giesel FL, Haberkorn U. FAPI PET: fibroblast activation protein inhibitor use in oncologic and nononcologic disease. Radiology. 2023;306:e220749. https:\/\/doi.org\/10.1148\/radiol.220749","journal-title":"Radiology"},{"key":"6986_CR12","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1093\/rheumatology\/keh542","volume":"44","author":"CD Buckley","year":"2005","unstructured":"Buckley CD, Rainger GE, Nash GB, Raza K. Endothelial cells, fibroblasts and vasculitis. Rheumatology (Oxford). 2005;44:860\u20133. https:\/\/doi.org\/10.1093\/rheumatology\/keh542","journal-title":"Rheumatology (Oxford)"},{"key":"6986_CR13","doi-asserted-by":"publisher","first-page":"151728","DOI":"10.1016\/j.anndiagpath.2021.151728","volume":"52","author":"S Parreau","year":"2021","unstructured":"Parreau S, Vedrenne N, Regent A, Richard L, Sindou P, Mouthon L, et al. An immunohistochemical analysis of fibroblasts in giant cell arteritis. Ann Diagn Pathol. 2021;52:151728. https:\/\/doi.org\/10.1016\/j.anndiagpath.2021.151728","journal-title":"Ann Diagn Pathol"},{"issue":"6","key":"6986_CR14","doi-asserted-by":"publisher","first-page":"103574","DOI":"10.1016\/j.autrev.2024.103574","volume":"23","author":"S Xu","year":"2024","unstructured":"Xu S, Jiemy WF, Brouwer E, Burgess JK, Heeringa P, van der Geest KSM, et al. Current evidence on the role of fibroblasts in large-vessel vasculitides: from pathogenesis to therapeutics. Autoimmun Rev. 2024;23(6):103574. https:\/\/doi.org\/10.1016\/j.autrev.2024.103574","journal-title":"Autoimmun Rev"},{"key":"6986_CR15","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1097\/RLU.0000000000003692","volume":"46","author":"S Wu","year":"2021","unstructured":"Wu S, Pang Y, Zhao L, Zhao L, Chen H. 68Ga-FAPI PET\/CT versus 18F-FDG PET\/CT for the evaluation of disease activity in Takayasu arteritis. Clin Nucl Med. 2021;46:847\u20139. https:\/\/doi.org\/10.1097\/RLU.0000000000003692","journal-title":"Clin Nucl Med"},{"key":"6986_CR16","doi-asserted-by":"publisher","unstructured":"R\u00f6hrich M, Rosales JJ, Hoppner J, Kvacskay P, Blank N, Loi L, et al. Fibroblast activation protein inhibitor-positron emission tomography in aortitis: fibroblast pathology in active inflammation and remission. Rheumatology (Oxford). Published Online April. 2024;22. https:\/\/doi.org\/10.1093\/rheumatology\/keae225","DOI":"10.1093\/rheumatology\/keae225"},{"issue":"12","key":"6986_CR17","doi-asserted-by":"publisher","first-page":"1654","DOI":"10.1136\/ard-2022-223482","volume":"81","author":"PC Grayson","year":"2022","unstructured":"Grayson PC, Ponte C, Suppiah R, Robson JC, Gribbons KB, Judge A, et al. 2022 American College of Rheumatology\/EULAR classification criteria for Takayasu arteritis. Ann Rheum Dis. 2022;81(12):1654\u201360. https:\/\/doi.org\/10.1136\/ard-2022-223482","journal-title":"Ann Rheum Dis"},{"issue":"12","key":"6986_CR18","doi-asserted-by":"publisher","first-page":"1647","DOI":"10.1136\/ard-2022-223480","volume":"81","author":"C Ponte","year":"2022","unstructured":"Ponte C, Grayson PC, Robson JC, Suppiah R, Gribbons KB, Judge A, et al. 2022 American College of Rheumatology\/EULAR classification criteria for giant cell arteritis. Ann Rheum Dis. 2022;81(12):1647\u201353. https:\/\/doi.org\/10.1136\/ard-2022-223480","journal-title":"Ann Rheum Dis"},{"key":"6986_CR19","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.1002\/art.1780330805","volume":"33","author":"RW Lightfoot Jr","year":"1990","unstructured":"Lightfoot RW Jr, Michel BA, Bloch DA, Hunder GG, Zvaifler NJ, McShane DJ, et al. The American College of Rheumatology 1990 criteria for the classification of polyarteritis nodosa. Arthritis Rheum. 1990;33:1088\u201393. https:\/\/doi.org\/10.1002\/art.1780330805","journal-title":"Arthritis Rheum"},{"key":"6986_CR20","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1111\/jdv.12107","volume":"28","author":"International Team for the Revision of the International Criteria for Beh\u00e7et\u2019s Disease (ITR-ICBD)","year":"2014","unstructured":"International Team for the Revision of the International Criteria for Beh\u00e7et\u2019s Disease (ITR-ICBD). The International Criteria for Beh\u00e7et\u2019s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol. 2014;28:338\u201347. https:\/\/doi.org\/10.1111\/jdv.12107","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"6986_CR21","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1136\/annrheumdis-2021-221795","volume":"81","author":"JC Robson","year":"2022","unstructured":"Robson JC, Grayson PC, Ponte C, Suppiah R, Craven A, Judge A, et al. 2022 American College of Rheumatology\/European Alliance of Associations for Rheumatology classification criteria for granulomatosis with polyangiitis. Ann Rheum Dis. 2022;81:315\u201320. https:\/\/doi.org\/10.1136\/annrheumdis-2021-221795","journal-title":"Ann Rheum Dis"},{"key":"6986_CR22","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1136\/annrheumdis-2021-221796","volume":"81","author":"R Suppiah","year":"2022","unstructured":"Suppiah R, Robson JC, Grayson PC, Ponte C, Craven A, Khalid S, et al. 2022 American College of Rheumatology\/European Alliance of Associations for Rheumatology classification criteria for microscopic polyangiitis. Ann Rheum Dis. 2022;81:321\u20136. https:\/\/doi.org\/10.1136\/annrheumdis-2021-221796","journal-title":"Ann Rheum Dis"},{"key":"6986_CR23","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1136\/annrheumdis-2021-221794","volume":"81","author":"PC Grayson","year":"2022","unstructured":"Grayson PC, Ponte C, Suppiah R, Robson JC, Craven A, Judge A, et al. 2022 American College of Rheumatology\/European Alliance of Associations for Rheumatology Classification Criteria for Eosinophilic granulomatosis with Polyangiitis. Ann Rheum Dis. 2022;81:309\u201314. https:\/\/doi.org\/10.1136\/annrheumdis-2021-221794","journal-title":"Ann Rheum Dis"},{"key":"6986_CR24","doi-asserted-by":"publisher","first-page":"4259","DOI":"10.1007\/s00259-021-05470-5","volume":"48","author":"S Wang","year":"2021","unstructured":"Wang S, Zhou X, Xu X, Ding J, Liu S, Hou X, et al. Clinical translational evaluation of Al18F-NOTA-FAPI for fibroblast activation protein-targeted tumour imaging. Eur J Nucl Med Mol Imaging. 2021;48:4259\u201371. https:\/\/doi.org\/10.1007\/s00259-021-05470-5","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"7","key":"6986_CR25","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1007\/s00259-018-4021-4","volume":"45","author":"BD Nielsen","year":"2018","unstructured":"Nielsen BD, Gormsen LC, Hansen IT, Keller KK, Therkildsen P, Hauge EM. Three days of high-dose glucocorticoid treatment attenuates large-vessel 18F-FDG uptake in large-vessel giant cell arteritis but with a limited impact on diagnostic accuracy. Eur J Nucl Med Mol Imaging. 2018;45(7):1119\u201328. https:\/\/doi.org\/10.1007\/s00259-018-4021-4","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"6986_CR26","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1007\/s00259-003-1209-y","volume":"30","author":"T Belhocine","year":"2003","unstructured":"Belhocine T, Blockmans D, Hustinx R, Vandevivere J, Mortelmans L. Imaging of large vessel vasculitis with (18)FDG PET: illusion or reality? A critical review of the literature data. Eur J Nucl Med Mol Imaging. 2003;30:1305\u201313. https:\/\/doi.org\/10.1007\/s00259-003-1209-y","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"6986_CR27","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1007\/s00393-015-1674-2","volume":"75","author":"YH Lee","year":"2016","unstructured":"Lee YH, Choi SJ, Ji JD, Song GG. Diagnostic accuracy of 18F-FDG PET or PET\/CT for large vessel vasculitis: a meta-analysis. Z Rheumatol. 2016;75:924\u201331. https:\/\/doi.org\/10.1007\/s00393-015-1674-2","journal-title":"Z Rheumatol"},{"key":"6986_CR28","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1093\/ehjci\/jeaa229","volume":"22","author":"W Gao","year":"2021","unstructured":"Gao W, Gong JN, Guo XJ, Wu JY, Xi XY, Ma ZH, et al. Value of 18F-fluorodeoxyglucose positron emission tomography\/computed tomography in the evaluation of pulmonary artery activity in patients with Takayasu\u2019s arteritis. Eur Heart J Cardiovasc Imaging. 2021;22:541\u201350. https:\/\/doi.org\/10.1093\/ehjci\/jeaa229","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"6986_CR29","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1007\/s00259-018-4194-x","volume":"46","author":"M Eskian","year":"2019","unstructured":"Eskian M, Alavi A, Khorasanizadeh M, Viglianti BL, Jacobsson H, Barwick TD, et al. Effect of blood glucose level on standardized uptake value (SUV) in (18)F- FDG PET-scan: a systematic review and meta-analysis of 20,807 individual SUV measurements. Eur J Nucl Med Mol Imaging. 2019;46:224\u201337. https:\/\/doi.org\/10.1007\/s00259-018-4194-x","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"6986_CR30","doi-asserted-by":"publisher","unstructured":"van Praagh GD, Nienhuis PH, de Jong DM, Reijrink M, van der Geest KSM, Brouwer E, et al. Toward reliable uptake metrics in large vessel vasculitis studies. Diagnostics (Basel). 2021;11. https:\/\/doi.org\/10.3390\/diagnostics11111986","DOI":"10.3390\/diagnostics11111986"},{"issue":"2","key":"6986_CR31","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1093\/rheumatology\/keh025","volume":"43","author":"M Brodmann","year":"2004","unstructured":"Brodmann M, Lipp RW, Passath A, Seinost G, Pabst E, Pilger E. The role of 2-18F-fluoro-2-deoxy-D-glucose positron emission tomography in the diagnosis of giant cell arteritis of the temporal arteries. Rheumatology (Oxford). 2004;43(2):241\u20132. https:\/\/doi.org\/10.1093\/rheumatology\/keh025","journal-title":"Rheumatology (Oxford)"},{"key":"6986_CR32","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.autrev.2013.09.009","volume":"13","author":"M Soussan","year":"2014","unstructured":"Soussan M, Abisror N, Abad S, Nunes H, Terrier B, Pop G, et al. FDG-PET\/CT in patients with ANCA-associated vasculitis: case-series and literature review. Autoimmun Rev. 2014;13:125\u201331. https:\/\/doi.org\/10.1016\/j.autrev.2013.09.009","journal-title":"Autoimmun Rev"},{"key":"6986_CR33","doi-asserted-by":"publisher","first-page":"3886","DOI":"10.1007\/s00259-021-05362-8","volume":"48","author":"KSM van der Geest","year":"2021","unstructured":"van der Geest KSM, Treglia G, Glaudemans A, Brouwer E, Sandovici M, Jamar F, et al. Diagnostic value of [18F]FDG-PET\/CT for treatment monitoring in large vessel vasculitis: a systematic review and meta-analysis. Eur J Nucl Med Mol Imaging. 2021;48:3886\u2013902. https:\/\/doi.org\/10.1007\/s00259-021-05362-8","journal-title":"Eur J Nucl Med Mol Imaging"}],"container-title":["European Journal of Nuclear Medicine and Molecular Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00259-024-06986-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00259-024-06986-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00259-024-06986-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T23:28:56Z","timestamp":1737502136000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00259-024-06986-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,27]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["6986"],"URL":"https:\/\/doi.org\/10.1007\/s00259-024-06986-2","relation":{},"ISSN":["1619-7070","1619-7089"],"issn-type":[{"value":"1619-7070","type":"print"},{"value":"1619-7089","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,27]]},"assertion":[{"value":"5 July 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 November 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 November 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was performed in line with the principles of the Declaration of Helsinki and approved by the institutional review board (2022\u00a0K-12).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individual participants included in this study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors affirm that human research participants provided informed consent for publication of the images in Figs.\u00a0\n                      \n                      ,\n                      \n                      and\n                      \n                      .","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}