{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T16:42:46Z","timestamp":1793292166983,"version":"4.5.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82422039"],"award-info":[{"award-number":["82422039"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Fujian Research and Training Grants for Young and China","award":["Fujian Research and Training Grants for Young and China"],"award-info":[{"award-number":["Fujian Research and Training Grants for Young and China"]}]},{"name":"Key Scientific Research Program for Yong Scholars in Fujian","award":["2021ZQNZD016"],"award-info":[{"award-number":["2021ZQNZD016"]}]},{"name":"Fujian Natural Science Foundation for Distinguished Yong Scholars","award":["2022D005"],"award-info":[{"award-number":["2022D005"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Nucl Med Mol Imaging"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1007\/s00259-025-07108-2","type":"journal-article","created":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T06:40:17Z","timestamp":1738219217000},"page":"2317-2334","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["FAP-targeted PET\/CT imaging in patients with breast cancer from a prospective bi-center study: insights into diagnosis and clinic management"],"prefix":"10.1007","volume":"52","author":[{"given":"Wei","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weizhi","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tinghua","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunlei","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizhen","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingxiong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanjun","family":"Mi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinlu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9101-8884","authenticated-orcid":false,"given":"Haojun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,30]]},"reference":[{"issue":"3","key":"7108_CR1","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","volume":"71","author":"H Sung","year":"2021","unstructured":"Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer statistics 2020: GLOBOCAN estimates of incidence and Mortality Worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209\u201349. https:\/\/doi.org\/10.3322\/caac.21660.","journal-title":"CA Cancer J Clin"},{"issue":"5","key":"7108_CR2","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1016\/j.rcl.2021.05.004","volume":"59","author":"AM Fowler","year":"2021","unstructured":"Fowler AM. Cho.PET imaging for breast Cancer. Radiol Clin North Am. 2021;59(5):725\u201335. https:\/\/doi.org\/10.1016\/j.rcl.2021.05.004.","journal-title":"Radiol Clin North Am"},{"issue":"20","key":"7108_CR3","doi-asserted-by":"publisher","first-page":"3495","DOI":"10.1200\/JCO.2000.18.20.3495","volume":"18","author":"N Avril","year":"2000","unstructured":"Avril N, Ros\u00e9 CA, Schelling M, Dose J, Kuhn W, Bense S, et al. Breast imaging with positron emission tomography and fluorine-18 fluorodeoxyglucose: use and limitations. J Clin Oncol. 2000;18(20):3495\u2013502. https:\/\/doi.org\/10.1200\/JCO.2000.18.20.3495.","journal-title":"J Clin Oncol"},{"issue":"1","key":"7108_CR4","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1007\/s12282-015-0613-z","volume":"23","author":"H Kurihara","year":"2016","unstructured":"Kurihara H, Shimizu C, Miyakita Y, Yoshida M, Hamada A, Kanayama Y, et al. Molecular imaging using PET for breast cancer. Breast Cancer. 2016;23(1):24\u201332. https:\/\/doi.org\/10.1007\/s12282-015-0613-z.","journal-title":"Breast Cancer"},{"issue":"Suppl 1","key":"7108_CR5","doi-asserted-by":"publisher","first-page":"S125","DOI":"10.1007\/s00259-004-1535-8","volume":"31","author":"P Lind","year":"2004","unstructured":"Lind P, Igerc I, Beyer T, Reinprecht P, Hausegger K. Advantages and limitations of FDG PET in the follow-up of breast cancer. Eur J Nucl Med Mol Imaging. 2004;31(Suppl 1):S125\u201334. https:\/\/doi.org\/10.1007\/s00259-004-1535-8.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"3","key":"7108_CR6","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/s11604-010-0531-0","volume":"29","author":"Y Hirose","year":"2011","unstructured":"Hirose Y, Kaida H, Ishibashi M, Kawahara A, Kobayashi M, Hayabuchi N. Glucose transporter expression of intraductal papilloma of the breast detected by fluorodeoxyglucose positron emission tomography. Jpn J Radiol. 2011;29(3):217\u201321. https:\/\/doi.org\/10.1007\/s11604-010-0531-0.","journal-title":"Jpn J Radiol"},{"issue":"1","key":"7108_CR7","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1007\/s00259-020-04940-6","volume":"48","author":"H Chen","year":"2021","unstructured":"Chen H, Zhao L, Ruan D, Pang Y, Hao B, Dai Y, et al. Usefulness of [68Ga]Ga-DOTA-FAPI-04 PET\/CT in patients presenting with inconclusive [18F]FDG PET\/CT findings. Eur J Nucl Med Mol Imaging. 2021;48(1):73\u201386. https:\/\/doi.org\/10.1007\/s00259-020-04940-6.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"5","key":"7108_CR8","doi-asserted-by":"publisher","first-page":"1604","DOI":"10.1007\/s00259-020-05095-0","volume":"48","author":"W Guo","year":"2021","unstructured":"Guo W, Pang Y, Yao L, Zhao L, Fan C, Ke J, et al. Imaging fibroblast activation protein in liver cancer: a single-center post hoc retrospective analysis to compare [68Ga]Ga-FAPI-04 PET\/CT versus MRI and [18F]-FDG PET\/CT. Eur J Nucl Med Mol Imaging. 2021;48(5):1604\u201317. https:\/\/doi.org\/10.1007\/s00259-020-05095-0.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"9","key":"7108_CR9","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.2967\/jnumed.118.210435","volume":"59","author":"A Loktev","year":"2018","unstructured":"Loktev A, Lindner T, Mier W, Debus J, Altmann A, J\u00e4ger D, et al. A tumor-imaging Method Targeting Cancer-Associated fibroblasts. J Nucl Med. 2018;59(9):1423\u20139. https:\/\/doi.org\/10.2967\/jnumed.118.210435.","journal-title":"J Nucl Med"},{"issue":"6","key":"7108_CR10","doi-asserted-by":"publisher","first-page":"801","DOI":"10.2967\/jnumed.119.227967","volume":"60","author":"C Kratochwil","year":"2019","unstructured":"Kratochwil C, Flechsig P, Lindner T, Abderrahim L, Altmann A, Mier W, et al. 68Ga-FAPI PET\/CT: Tracer Uptake in 28 different kinds of Cancer. J Nucl Med. 2019;60(6):801\u20135. https:\/\/doi.org\/10.2967\/jnumed.119.227967.","journal-title":"J Nucl Med"},{"issue":"8","key":"7108_CR11","doi-asserted-by":"publisher","first-page":"1820","DOI":"10.1007\/s00259-020-04769-z","volume":"47","author":"H Chen","year":"2020","unstructured":"Chen H, Pang Y, Wu J, Zhao L, Hao B, Wu J, et al. Comparison of [68Ga]Ga-DOTA-FAPI-04 and [18F] FDG PET\/CT for the diagnosis of primary and metastatic lesions in patients with various types of cancer. Eur J Nucl Med Mol Imaging. 2020;47(8):1820\u201332. https:\/\/doi.org\/10.1007\/s00259-020-04769-z.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"6","key":"7108_CR12","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1007\/s12149-021-01616-5","volume":"35","author":"H K\u00f6mek","year":"2021","unstructured":"K\u00f6mek H, Can C, G\u00fczel Y, Oru\u00e7 Z, G\u00fcndo\u011fan C, Yildirim \u00d6A, et al. 68Ga-FAPI-04 PET\/CT, a new step in breast cancer imaging: a comparative pilot study with the 18F-FDG PET\/CT. Ann Nucl Med. 2021;35(6):744\u201352. https:\/\/doi.org\/10.1007\/s12149-021-01616-5.","journal-title":"Ann Nucl Med"},{"issue":"11","key":"7108_CR13","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1097\/RLU.0000000000003263","volume":"45","author":"Y Pang","year":"2020","unstructured":"Pang Y, Zhao L, Chen H. 68Ga-FAPI outperforms 18F-FDG PET\/CT in identifying bone metastasis and Peritoneal Carcinomatosis in a patient with metastatic breast Cancer. Clin Nucl Med. 2020;45(11):913\u20135. https:\/\/doi.org\/10.1097\/RLU.0000000000003263.","journal-title":"Clin Nucl Med"},{"issue":"6","key":"7108_CR14","doi-asserted-by":"publisher","first-page":"2096","DOI":"10.1007\/s00259-021-05664-x","volume":"49","author":"Q Shang","year":"2022","unstructured":"Shang Q, Hao B, Xu W, Meng T, Pang Y, Sun L, et al. 68Ga-FAPI PET\/CT detected non-FDG-avid bone metastases in breast cancer. Eur J Nucl Med Mol Imaging. 2022;49(6):2096\u20137. https:\/\/doi.org\/10.1007\/s00259-021-05664-x.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"8","key":"7108_CR15","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1097\/RLU.0000000000004193","volume":"47","author":"W Xu","year":"2022","unstructured":"Xu W, Meng T, Shang Q, Pang Y, Chen H. Uncommon metastases from occult breast Cancer revealed by 18 F-FDG and 68 Ga-FAPI PET\/CT. Clin Nucl Med. 2022;47(8):751\u20133. https:\/\/doi.org\/10.1097\/RLU.0000000000004193.","journal-title":"Clin Nucl Med"},{"key":"7108_CR16","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1007\/s11307-021-01679-w","volume":"24","author":"Y Li","year":"2021","unstructured":"Li Y, Lin X, Li Y, et al. Clinical utility of F-18 labeled fibroblast activation protein inhibitor (FAPI) for primary staging in lung adeno-carcinoma: a prospective study. Mol Imaging Biol. 2021;24:309\u201320. https:\/\/doi.org\/10.1007\/s11307-021-01679-w.","journal-title":"Mol Imaging Biol"},{"issue":"2","key":"7108_CR17","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1148\/radiol.2392042127","volume":"239","author":"E Lazarus","year":"2006","unstructured":"Lazarus E, Mainiero MB, Schepps B, Koelliker SL, Livingston LS. BI-RADS lexicon for US and mammography: interobserver variability and positive predictive value. Radiology. 2006;239(2):385\u201391. https:\/\/doi.org\/10.1148\/radiol.2392042127.","journal-title":"Radiology"},{"issue":"1","key":"7108_CR18","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1002\/jcu.20298","volume":"35","author":"L Chala","year":"2007","unstructured":"Chala L, Endo E, Kim S, de Castro F, Moraes P, Cerri G, et al. Gray-scale sonography of solid breast masses: diagnosis of probably benign masses and reduction of the number of biopsies. J Clin Ultrasound. 2007;35(1):9\u201319. https:\/\/doi.org\/10.1002\/jcu.20298.","journal-title":"J Clin Ultrasound"},{"key":"7108_CR19","unstructured":"Mendelson EB, B\u00f6hm-V\u00e9lez M, Berg WA et al. ACR BI-RADS Ultrasound. In: ACR BI-RADS Atlas, Breast Imaging Reporting and Data System, 5th Edition, American College of Radiology, Reston;2013."},{"key":"7108_CR20","doi-asserted-by":"publisher","first-page":"e420","DOI":"10.1097\/rlu.0000000000004751","volume":"48","author":"G Al\u00e7\u0131n","year":"2023","unstructured":"Al\u00e7\u0131n G, Arslan E, Aksoy T, Cin M, Erol Fenercio\u011flu \u00d6, Beyhan E, et al. 68Ga-FAPI-04 PET\/CT in selected breast Cancer patients with low FDG Affinity. Clin Nucl Med. 2023;48:e420\u201330. https:\/\/doi.org\/10.1097\/rlu.0000000000004751.","journal-title":"Clin Nucl Med"},{"issue":"11","key":"7108_CR21","doi-asserted-by":"publisher","first-page":"1908","DOI":"10.1007\/s00259-018-4043-y","volume":"45","author":"M Spadafora","year":"2018","unstructured":"Spadafora M, Pace L, Evangelista L, Mansi L, Del Prete F, Saladini G, et al. Risk-related 18F-FDG PET\/CT and new diagnostic strategies in patients with solitary pulmonary nodule: the ITALIAN multicenter trial. Eur J Nucl Med Mol Imaging. 2018;45(11):1908\u201314. https:\/\/doi.org\/10.1007\/s00259-018-4043-y.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"5","key":"7108_CR22","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1177\/2050640616684697","volume":"5","author":"E Redondo-Cerezo","year":"2017","unstructured":"Redondo-Cerezo E, Mart\u00ednez-Cara JG, Jim\u00e9nez-Rosales R, Valverde-L\u00f3pez F, Caballero-Mateos A, J\u00e9rvez-Puente P, et al. Endoscopic ultrasound in gastric cancer staging before and after neoadjuvant chemotherapy. A comparison with PET-CT in a clinical series. United Eur Gastroenterol J. 2017;5(5):641\u20137. https:\/\/doi.org\/10.1177\/2050640616684697.","journal-title":"United Eur Gastroenterol J"},{"issue":"1","key":"7108_CR23","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1007\/s10549-010-0917-9","volume":"122","author":"TM Weissenbacher","year":"2010","unstructured":"Weissenbacher TM, Zschage M, Janni W, Jeschke U, Dimpfl T, Mayr D, et al. Multicentric and multifocal versus unifocal breast cancer: is the tumor-node-metastasis classification justified? Breast Cancer Res Treat. 2010;122(1):27\u201334. https:\/\/doi.org\/10.1007\/s10549-010-0917-9.","journal-title":"Breast Cancer Res Treat"},{"issue":"8","key":"7108_CR24","doi-asserted-by":"publisher","first-page":"e433","DOI":"10.1097\/RLU.0000000000003594","volume":"46","author":"C G\u00fcndo\u011fan","year":"2021","unstructured":"G\u00fcndo\u011fan C, G\u00fczel Y, Can C, Alabalik U, K\u00f6mek H. False-positive 68Ga-Fibroblast activation protein-specific inhibitor uptake of Benign lymphoid tissue in a patient with breast Cancer. Clin Nucl Med. 2021;46(8):e433\u20135. https:\/\/doi.org\/10.1097\/RLU.0000000000003594.","journal-title":"Clin Nucl Med"},{"issue":"6","key":"7108_CR25","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1097\/RLU.0000000000004069","volume":"47","author":"T Xu","year":"2022","unstructured":"Xu T, Wang W, Yang C, Cai L, Chen Y. 68Ga-DOTA-FAPI-04 uptake of accessory breast in a patient with breast Cancer. Clin Nucl Med. 2022;47(6):564\u20135. https:\/\/doi.org\/10.1097\/RLU.0000000000004069.","journal-title":"Clin Nucl Med"},{"key":"7108_CR26","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1148\/rg.2018180035","volume":"38","author":"SL Heller","year":"2018","unstructured":"Heller SL, Young Lin LL, Melsaether AN, Moy L, Gao Y. Hormonal effects on breast density, Fibroglandular Tissue, and background parenchymal enhancement. Radiographics: Rev Publication Radiological Soc North Am Inc. 2018;38:983\u201396. https:\/\/doi.org\/10.1148\/rg.2018180035.","journal-title":"Radiographics: Rev Publication Radiological Soc North Am Inc"},{"key":"7108_CR27","doi-asserted-by":"crossref","unstructured":"Sonni I, Lee-Felker S, Memarzadeh S, Quinn MM, Mona CE, L\u00fcckerath K et al. 68 Ga-FAPi-46 diffuse bilateral breast uptake in a patient with cervical cancer after hormonal stimulation. 2021;48:924\u20136.","DOI":"10.1007\/s00259-020-04947-z"},{"key":"7108_CR28","doi-asserted-by":"crossref","unstructured":"Wang L-j, Zhang Y, Wu H-bJCnm. Intense diffuse uptake of 68Ga-FAPI-04 in the breasts found by PET\/CT in a patient with advanced nasopharyngeal carcinoma. 2021;46:e293\u20135.","DOI":"10.1097\/RLU.0000000000003487"},{"key":"7108_CR29","doi-asserted-by":"publisher","unstructured":"Backhaus P, Burg MC, Roll W, B\u00fcther F, Breyholz HJ, Weigel S et al. Simultaneous FAPI PET\/MRI Targeting the Fibroblast-Activation Protein for Breast Cancer. Radiology. 2022;302:39\u201347. https:\/\/doi.org\/10.1148\/radiol.2021204677.","DOI":"10.1148\/radiol.2021204677"},{"key":"7108_CR30","unstructured":"National Comprehensive Cancer Network.\u2008NCCN Clinical Practice Guidelines in Oncology:Breast cancer, Version 6, 2020 [EB\/OL]. (2020-09-08) (2020-10-06).\u2008https:\/\/www.nccn.org\/professionals\/physician_gls\/default. Aspx."},{"key":"7108_CR31","doi-asserted-by":"publisher","unstructured":"K\u00f6mek H, Can C, G\u00fczel Y, Oru\u00e7 Z, G\u00fcndo\u011fan C, Yildirim \u00d6A et al. (68)Ga-FAPI-04 PET\/CT, a new step in breast cancer imaging: a comparative pilot study with the (18)F-FDG PET\/CT. Annals of nuclear medicine. 2021;35:744\u201352. https:\/\/doi.org\/10.1007\/s12149-021-01616-5","DOI":"10.1007\/s12149-021-01616-5"},{"key":"7108_CR32","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1097\/rlu.0000000000003279","volume":"45","author":"B Gu","year":"2020","unstructured":"Gu B, Luo Z, He X, Wang J, Song S. 68Ga-FAPI and 18F-FDG PET\/CT images in a patient with Extrapulmonary Tuberculosis mimicking malignant tumor. Clin Nucl Med. 2020;45:865\u20137. https:\/\/doi.org\/10.1097\/rlu.0000000000003279.","journal-title":"Clin Nucl Med"},{"key":"7108_CR33","doi-asserted-by":"publisher","unstructured":"Zheng S, Lin R, Chen S, Zheng J, Lin Z, Zhang Y et al. Characterization of the benign lesions with increased (68)Ga-FAPI-04 uptake in PET\/CT. Annals of nuclear medicine. 2021;35:1312\u201320. https:\/\/doi.org\/10.1007\/s12149-021-01673-w","DOI":"10.1007\/s12149-021-01673-w"},{"key":"7108_CR34","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.1007\/s12149-021-01672-x","volume":"35","author":"U Elboga","year":"2021","unstructured":"Elboga U, Sahin E, Kus T, Cayirli YB, Aktas G, Uzun E, et al. Superiority of (68)Ga-FAPI PET\/CT scan in detecting additional lesions compared to (18)FDG PET\/CT scan in breast cancer. Ann Nucl Med. 2021;35:1321\u201331. https:\/\/doi.org\/10.1007\/s12149-021-01672-x.","journal-title":"Ann Nucl Med"},{"issue":"1144","key":"7108_CR35","doi-asserted-by":"publisher","first-page":"20220994","DOI":"10.1259\/bjr.20220994","volume":"96","author":"Q Shu","year":"2023","unstructured":"Shu Q, Wang Y, Deng M, Chen X, Liu M, Cai L. Benign lesions with 68Ga-FAPI uptake: a retrospective study. Br J Radiol. 2023;96(1144):20220994. https:\/\/doi.org\/10.1259\/bjr.20220994.","journal-title":"Br J Radiol"},{"issue":"12","key":"7108_CR36","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.1007\/s12149-021-01672-x","volume":"35","author":"U Elboga","year":"2021","unstructured":"Elboga U, Sahin E, Kus T, Cayirli YB, Aktas G, Uzun E, et al. Superiority of 68Ga-FAPI PET\/CT scan in detecting additional lesions compared to 18FDG PET\/CT scan in breast cancer. Ann Nucl Med. 2021;35(12):1321\u201331. https:\/\/doi.org\/10.1007\/s12149-021-01672-x.","journal-title":"Ann Nucl Med"},{"issue":"12","key":"7108_CR37","doi-asserted-by":"publisher","first-page":"2836","DOI":"10.1007\/s00259-020-04859-y","volume":"47","author":"M Syed","year":"2020","unstructured":"Syed M, Flechsig P, Liermann J, Windisch P, Staudinger F, Akbaba S, et al. Fibroblast activation protein inhibitor (FAPI) PET for diagnostics and advanced targeted radiotherapy in head and neck cancers. Eur J Nucl Med Mol Imaging. 2020;47(12):2836\u201345. https:\/\/doi.org\/10.1007\/s00259-020-04859-y.","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"7108_CR38","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.radonc.2021.02.015","volume":"158","author":"L Zhao","year":"2021","unstructured":"Zhao L, Chen S, Chen S, Pang Y, Dai Y, Hu S, et al. 68Ga-fibroblast activation protein inhibitor PET\/CT on gross tumor volume delineation for radiotherapy planning of oesophageal cancer. Radiother Oncol. 2021;158:55\u201361. https:\/\/doi.org\/10.1016\/j.radonc.2021.02.015.","journal-title":"Radiother Oncol"},{"issue":"9","key":"7108_CR39","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.2967\/jnumed.119.237016","volume":"61","author":"SA Koerber","year":"2020","unstructured":"Koerber SA, Staudinger F, Kratochwil C, Adeberg S, Haefner MF, Ungerechts G, et al. The role of 68Ga-FAPI PET\/CT for patients with malignancies of the Lower Gastrointestinal Tract: first clinical experience. J Nucl Med. 2020;61(9):1331\u20136. https:\/\/doi.org\/10.2967\/jnumed.119.237016.","journal-title":"J Nucl Med"},{"issue":"1","key":"7108_CR40","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1148\/radiol.2021204677","volume":"302","author":"P Backhaus","year":"2022","unstructured":"Backhaus P, Burg MC, Roll W, B\u00fcther F, Breyholz HJ, Weigel S, et al. Simultaneous FAPI PET\/MRI targeting the fibroblast-activation protein for breast Cancer. Radiology. 2022;302(1):39\u201347. https:\/\/doi.org\/10.1148\/radiol.2021204677.","journal-title":"Radiology"},{"key":"7108_CR41","doi-asserted-by":"publisher","first-page":"2549","DOI":"10.1016\/j.humpath.2013.06.016","volume":"44","author":"J Tchou","year":"2013","unstructured":"Tchou J, Zhang PJ, Bi Y, Satija C, Marjumdar R, Stephen TL, et al. Fibroblast activation protein expression by stromal cells and tumor-associated macrophages in human breast cancer. Hum Pathol. 2013;44:2549\u201357. https:\/\/doi.org\/10.1016\/j.humpath.2013.06.016.","journal-title":"Hum Pathol"},{"key":"7108_CR42","doi-asserted-by":"publisher","first-page":"e104","DOI":"10.1097\/rlu.0000000000004523","volume":"48","author":"S Zheng","year":"2023","unstructured":"Zheng S, Lin J, Zhu Y, Chen Y, Zhang J, Chen X, et al. 68Ga-FAPI Versus 18F-FDG PET\/CT in evaluating newly diagnosed breast Cancer patients: a Head-to-head comparative study. Clin Nucl Med. 2023;48:e104\u20139. https:\/\/doi.org\/10.1097\/rlu.0000000000004523.","journal-title":"Clin Nucl Med"},{"key":"7108_CR43","doi-asserted-by":"publisher","unstructured":"\u00d6nner H, Coskun N, Erol M, Eren Karanis M\u0130. Association of 18F-FDG PET\/CT textural features with immunohistochemical characteristics in invasive ductal breast cancer. Rev Esp Med Nucl Imagen Mol (Engl Ed). 2022 Jan-Feb;41(1):11\u20136. https:\/\/doi.org\/10.1016\/j.remnie.2020.12.009","DOI":"10.1016\/j.remnie.2020.12.009"},{"key":"7108_CR44","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-021-05646-z","author":"K Hu","year":"2021","unstructured":"Hu K, Wang L, Wu H, et al. [18F]FAPI-42 PET imaging in cancer patients: optimal acquisition time, biodistribution, and comparison with [68Ga]Ga-FAPI-04. Eur J Nucl Med Mol Imaging. 2021. https:\/\/doi.org\/10.1007\/s00259-021-05646-z.","journal-title":"Eur J Nucl Med Mol Imaging"}],"container-title":["European Journal of Nuclear Medicine and Molecular Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00259-025-07108-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00259-025-07108-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00259-025-07108-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T10:18:09Z","timestamp":1748427489000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00259-025-07108-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,30]]},"references-count":44,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["7108"],"URL":"https:\/\/doi.org\/10.1007\/s00259-025-07108-2","relation":{},"ISSN":["1619-7070","1619-7089"],"issn-type":[{"value":"1619-7070","type":"print"},{"value":"1619-7089","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,30]]},"assertion":[{"value":"29 October 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All procedures involving human participants were carried out in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. This article does not contain any experiments with animals.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"None.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}