{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T05:28:27Z","timestamp":1781674107361,"version":"3.54.5"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T00:00:00Z","timestamp":1764979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T00:00:00Z","timestamp":1764979200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Nucl Med Mol Imaging"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1007\/s00259-025-07665-6","type":"journal-article","created":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T01:42:42Z","timestamp":1764985362000},"page":"3238-3245","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Polymyalgia rheumatica patients presenting with atypical clinical features still exhibit characteristic 18F-FDG PET\/CT findings"],"prefix":"10.1007","volume":"53","author":[{"given":"Emily","family":"Martin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2432-5451","authenticated-orcid":false,"given":"Christopher R.","family":"McMaster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurora MT","family":"Poon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6796-7134","authenticated-orcid":false,"given":"Saskia J.","family":"Rowson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3834-2706","authenticated-orcid":false,"given":"Bonnia","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8451-8883","authenticated-orcid":false,"given":"Jessica L.","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6656-295X","authenticated-orcid":false,"given":"David FL","family":"Liew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew M.","family":"Scott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2694-5411","authenticated-orcid":false,"given":"Claire E.","family":"Owen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,6]]},"reference":[{"issue":"10411","key":"7665_CR1","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.1016\/S0140-6736(23)01310-7","volume":"402","author":"G Esp\u00edgol-Frigol\u00e9","year":"2023","unstructured":"Esp\u00edgol-Frigol\u00e9 G, Dejaco C, Mackie SL, Salvarani C, Matteson EL, Cid MC. Polymyalgia rheumatica. Lancet. 2023;402(10411):1459\u201372.","journal-title":"Lancet"},{"key":"7665_CR2","unstructured":"Pease C, Haugeberg G, Morgan A, Montague B, Hensor E, Bhakta B Diagnosing late onset rheumatoid arthritis, polymyalgia rheumatica, and temporal arteritis in patients presenting with polymyalgic symptoms. A prospective longterm evaluation. J Rheumatol 2005 July 1:1043\u20136"},{"key":"7665_CR3","unstructured":"Gonzalez-Gay M, Garcia-Porrua C, Salvarani C, Olivieri I, Hunder G The spectrum of conditions mimicking polymyalgia rheumatica in Northwestern Spain. J Rheumatol 1:2179\u201384"},{"key":"7665_CR4","doi-asserted-by":"crossref","unstructured":"Owen CE, Poon AMT, Yang V, McMaster C, Lee ST, Liew DFL et al Abnormalities at three musculoskeletal sites on whole-body positron emission tomography\/computed tomography can diagnose polymyalgia rheumatica with high sensitivity and specificity. Eur J Nucl Med Mol Imaging 47(10):2461\u20138","DOI":"10.1007\/s00259-020-04731-z"},{"key":"7665_CR5","doi-asserted-by":"publisher","first-page":"152017","DOI":"10.1016\/j.semarthrit.2022.152017","volume":"55","author":"AK Hemmig","year":"2022","unstructured":"Hemmig AK, Gozzoli D, Werlen L, Ewald H, Aschwanden M, Blockmans D, et al. Subclinical giant cell arteritis in new onset polymyalgia rheumatica A systematic review and meta-analysis of individual patient data. Semin Arthritis Rheum. 2022;55:152017.","journal-title":"Semin Arthritis Rheum"},{"issue":"10103","key":"7665_CR6","doi-asserted-by":"publisher","first-page":"1700","DOI":"10.1016\/S0140-6736(17)31825-1","volume":"390","author":"MA Gonz\u00e1lez-Gay","year":"2017","unstructured":"Gonz\u00e1lez-Gay MA, Matteson EL, Casta\u00f1eda S. Polymyalgia rheumatica. Lancet. 2017;390(10103):1700\u201312.","journal-title":"Lancet"},{"key":"7665_CR7","doi-asserted-by":"crossref","unstructured":"Owen C, Poon A, Lee S, Yap L, Zwar R, McMenamin C et al (2017) Fusion of positron emission tomography\/computed tomography with magnetic resonance imaging reveals hamstring peritendonitis in polymyalgia rheumatica. Rheumatol Oxf Engl 57","DOI":"10.1093\/rheumatology\/kex411"},{"issue":"1","key":"7665_CR8","doi-asserted-by":"publisher","first-page":"rkae003","DOI":"10.1093\/rap\/rkae003","volume":"8","author":"CE Owen","year":"2024","unstructured":"Owen CE, Poon AM, Liu B, Liew DF, Yap LP, Yang V, et al. Characterising polymyalgia rheumatica on whole-body 18F-FDG PET\/CT: an atlas. Rheumatol Adv Pract. 2024;8(1):rkae003.","journal-title":"Rheumatol Adv Pract"},{"key":"7665_CR9","doi-asserted-by":"publisher","first-page":"1026944","DOI":"10.3389\/fmed.2022.1026944","volume":"9","author":"L Moreel","year":"2022","unstructured":"Moreel L, Boeckxstaens L, Betrains A, Van Hemelen M, Vanderschueren S, Van Laere K, et al. Diagnostic accuracy and validation of 18F-fluorodeoxyglucose positron emission tomography scores in a large cohort of patients with polymyalgia rheumatica. Front Med. 2022;9:1026944.","journal-title":"Front Med"},{"issue":"3","key":"7665_CR10","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.1093\/rheumatology\/keab483","volume":"61","author":"KSM van der Geest","year":"2022","unstructured":"van der Geest KSM, van Sleen Y, Nienhuis P, Sandovici M, Westerdijk N, Glaudemans AWJM, et al. Comparison and validation of FDG-PET\/CT scores for polymyalgia rheumatica. Rheumatology. 2022;61(3):1072\u201382.","journal-title":"Rheumatology"},{"issue":"4","key":"7665_CR11","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1136\/annrheumdis-2011-200329","volume":"71","author":"B Dasgupta","year":"2012","unstructured":"Dasgupta B, Cimmino MA, Maradit-Kremers H, Schmidt WA, Schirmer M, Salvarani C, et al. 2012 provisional classification criteria for polymyalgia rheumatica: a European league against Rheumatism\/American college of rheumatology collaborative initiative. Ann Rheum Dis. 2012;71(4):484\u201392.","journal-title":"Ann Rheum Dis"},{"issue":"7","key":"7665_CR12","doi-asserted-by":"publisher","first-page":"1250","DOI":"10.1007\/s00259-018-3973-8","volume":"45","author":"RHJA Slart","year":"2018","unstructured":"Slart RHJA, Slart RHJA, Glaudemans AWJM, Chareonthaitawee P, Treglia G, Besson FL et al (2018) FDG-PET\/CT(A) imaging in large vessel vasculitis and polymyalgia rheumatica: joint procedural recommendation of the EANM, SNMMI, and the PET Interest Group (PIG), and endorsed by the ASNC. Eur J Nucl Med Mol Imaging 45(7):1250\u201369","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"7665_CR13","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.ymeth.2020.10.004","volume":"188","author":"LKS Sundar","year":"2021","unstructured":"Sundar LKS, Muzik O, Buvat I, Bidaut L, Beyer T. Potentials and caveats of AI in hybrid imaging. Methods. 2021;188:4\u201319.","journal-title":"Methods"},{"issue":"3","key":"7665_CR14","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1148\/radiol.2018180940","volume":"290","author":"KT Chen","year":"2019","unstructured":"Chen KT, Gong E, de Carvalho Macruz FB, Xu J, Boumis A, Khalighi M, et al. Ultra\u2013low-dose 18F-florbetaben amyloid PET imaging using deep learning with multi-contrast MRI inputs. Radiology. 2019;290(3):649\u201356.","journal-title":"Radiology"},{"key":"7665_CR15","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1007\/s00259-003-1144-y","volume":"30","author":"J Meller","year":"2003","unstructured":"Meller J, Strutz F, Siefker U, Scheel A, Sahlmann C, Lehmann K, et al. Early diagnosis and follow-up of aortitis with [18 F] FDG PET and MRI. Eur J Nucl Med Mol Imaging. 2003;30:730\u20136.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"4","key":"7665_CR16","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1093\/rheumatology\/kel376","volume":"46","author":"D Blockmans","year":"2007","unstructured":"Blockmans D, De Ceuninck L, Vanderschueren S, Knockaert D, Mortelmans L, Bobbaers H. Repetitive 18-fluorodeoxyglucose positron emission tomography in isolated polymyalgia rheumatica: a prospective study in 35 patients. Rheumatol Oxf Engl. 2007;46(4):672\u20137.","journal-title":"Rheumatol Oxf Engl"},{"key":"7665_CR17","doi-asserted-by":"crossref","unstructured":"Kara M, Alp G, Koc A. Diagnostic difficulties in polymyalgia rheumatica cases with normal erythrocyte sedimentation rate and C-reactive protein values. Med (Baltim) 2023;102(39)","DOI":"10.1097\/MD.0000000000035385"},{"issue":"1","key":"7665_CR18","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1002\/art.20901","volume":"53","author":"C Salvarani","year":"2005","unstructured":"Salvarani C, Cantini F, Niccoli L, Macchioni P, Consonni D, Bajocchi G, et al. Acute-phase reactants and the risk of relapse\/recurrence in polymyalgia rheumatica: a prospective followup study. Arthritis Care Res. 2005;53(1):33\u20138.","journal-title":"Arthritis Care Res"},{"key":"7665_CR19","first-page":"866","volume-title":"Utility of erythrocyte sedimentation rate and C-reactive protein for the diagnosis of giant cell arteritis","author":"TA Kermani","year":"2012","unstructured":"Kermani TA, Schmidt J, Crowson CS, Ytterberg SR, Hunder GG, Matteson EL et al (2012) Utility of erythrocyte sedimentation rate and C-reactive protein for the diagnosis of giant cell arteritis. In Elsevier, pp 866\u201371"},{"issue":"6","key":"7665_CR20","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1186\/s13075-014-0492-2","volume":"16","author":"D Camellino","year":"2014","unstructured":"Camellino D, Paparo F, Morbelli S, Cutolo M, Sambuceti G, Cimmino MA. Interspinous bursitis is common in polymyalgia rheumatica, but is not associated with spinal pain. Arthritis Res Ther. 2014;16(6):492.","journal-title":"Arthritis Res Ther"},{"issue":"10","key":"7665_CR21","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1016\/j.crad.2023.06.007","volume":"78","author":"S Sun","year":"2023","unstructured":"Sun S, Shao X, Liu X, Jiang W, Zhang L, Chen J, et al. Assessing the feasibility of SUVindex (a metric derived from FDG PET\/CT) for the diagnosis of polymyalgia rheumatica. Clin Radiol. 2023;78(10):737\u201345.","journal-title":"Clin Radiol"},{"key":"7665_CR22","doi-asserted-by":"publisher","unstructured":"Pijl JP, Nienhuis PH, Kwee TC, Glaudemans AWJM, Slart RHJA, Gormsen LC. Limitations and pitfalls of FDG-PET\/CT in infection and Inflammation. Seminars in Nuclear Medicine. Var pitfalls PET-CT imaging part 2.2021;51(6):633\u201345. https:\/\/doi.org\/10.1053\/j.semnuclmed.2021.06.008","DOI":"10.1053\/j.semnuclmed.2021.06.008"},{"issue":"1","key":"7665_CR23","doi-asserted-by":"publisher","first-page":"rkaa005","DOI":"10.1093\/rap\/rkaa005","volume":"4","author":"M H\u00fcgle","year":"2020","unstructured":"H\u00fcgle M, Omoumi P, van Laar JM, Boedecker J, H\u00fcgle T. Applied machine learning and artificial intelligence in rheumatology. Rheumatol Adv Pract. 2020;4(1):rkaa005.","journal-title":"Rheumatol Adv Pract"},{"key":"7665_CR24","doi-asserted-by":"publisher","first-page":"100146","DOI":"10.1016\/j.cmpbup.2024.100146","volume":"5","author":"M Khalifa","year":"2024","unstructured":"Khalifa M, Albadawy M. AI in diagnostic imaging: revolutionising accuracy and efficiency. Comput Methods Programs Biomed Update. 2024;5:100146.","journal-title":"Comput Methods Programs Biomed Update"}],"container-title":["European Journal of Nuclear Medicine and Molecular Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00259-025-07665-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00259-025-07665-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00259-025-07665-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T01:26:16Z","timestamp":1774401976000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00259-025-07665-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,6]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["7665"],"URL":"https:\/\/doi.org\/10.1007\/s00259-025-07665-6","relation":{},"ISSN":["1619-7070","1619-7089"],"issn-type":[{"value":"1619-7070","type":"print"},{"value":"1619-7089","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,6]]},"assertion":[{"value":"7 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 October 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Approval was obtained from the ethics committee of Austin Health \u2013 HREC\/95689\/Austin-2023. The procedures used in this study adhere to the tenets of the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Author EM declares no competing interests.Author CM declares speaking honoraria from Abbvie.Author AP declares no competing interests.Author SR declares no competing interests.Author BL declares no competing interests.Author JL declares no competing interests.Author DL declares no competing interests. Author AS declares no competing interests. Author CO declares speaking honoraria from Abbvie, Fresenius Kabi, Janssen, Novartis and Roche, and consultancy for Abbvie.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}