{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T02:04:23Z","timestamp":1789697063861,"version":"4.0.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Nucl Med Mol Imaging"],"DOI":"10.1007\/s00259-026-08170-0","type":"journal-article","created":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T01:50:23Z","timestamp":1789696223000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Interventional strategies for inferior phrenic artery management in yttrium\u201190 selective internal radiation therapy for hepatocellular carcinoma: A single\u2011center retrospective study"],"prefix":"10.1007","author":[{"given":"Yong","family":"Liao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziwei","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junpeng","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaobin","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenkang","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shizhong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangxin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Bao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiantian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linxia","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Can","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mulan","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4092-5632","authenticated-orcid":false,"given":"Lin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahong","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,18]]},"reference":[{"issue":"11","key":"8170_CR1","doi-asserted-by":"publisher","first-page":"1649","DOI":"10.2967\/jnumed.116.186346","volume":"59","author":"N Voutsinas","year":"2018","unstructured":"Voutsinas N, Lekperic S, Barazani S, Titano JJ, Heiba SI, Kim E. Treatment of Primary Liver Tumors and Liver Metastases, Part 1: Nuclear Medicine Techniques. J Nucl Med. 2018;59(11):1649\u201354. https:\/\/doi.org\/10.2967\/jnumed.116.186346.","journal-title":"J Nucl Med"},{"issue":"4","key":"8170_CR2","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1002\/hep.29691","volume":"68","author":"R Salem","year":"2018","unstructured":"Salem R, Gabr A, Riaz A, Mora R, Ali R, Abecassis M, et al. Institutional decision to adopt Y90 as primary treatment for hepatocellular carcinoma informed by a 1,000-patient 15-year experience. Hepatology. 2018;68(4):1429\u201340. https:\/\/doi.org\/10.1002\/hep.29691.","journal-title":"Hepatology"},{"issue":"5","key":"8170_CR3","doi-asserted-by":"publisher","first-page":"2342","DOI":"10.1002\/hep.31819","volume":"74","author":"R Salem","year":"2021","unstructured":"Salem R, Johnson GE, Kim E, Riaz A, Bishay V, Boucher E, et al. Yttrium-90 Radioembolization for the Treatment of Solitary, Unresectable HCC: The LEGACY Study. Hepatology. 2021;74(5):2342\u201352. https:\/\/doi.org\/10.1002\/hep.31819.","journal-title":"Hepatology"},{"issue":"3","key":"8170_CR4","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1148\/radiol.211806","volume":"303","author":"E Dhondt","year":"2022","unstructured":"Dhondt E, Lambert B, Hermie L, Huyck L, Vanlangenhove P, Geerts A, et al. 90Y Radioembolization versus Drug-eluting Bead Chemoembolization for Unresectable Hepatocellular Carcinoma: Results from the TRACE Phase II Randomized Controlled Trial. Radiology. 2022;303(3):699\u2013710. https:\/\/doi.org\/10.1148\/radiol.211806.","journal-title":"Radiology"},{"issue":"3","key":"8170_CR5","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1148\/rg.2017160122","volume":"37","author":"AS Moustafa","year":"2017","unstructured":"Moustafa AS, Abdel Aal AK, Ertel N, Saad N, DuBay D, Saddekni S. Chemoembolization of Hepatocellular Carcinoma with Extrahepatic Collateral Blood Supply: Anatomic and Technical Considerations. Radiographics. 2017;37(3):963\u201377. https:\/\/doi.org\/10.1148\/rg.2017160122.","journal-title":"Radiographics"},{"issue":"7","key":"8170_CR6","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1007\/s11604-010-0456-7","volume":"28","author":"S Miyayama","year":"2010","unstructured":"Miyayama S, Yamashiro M, Yoshie Y, Okuda M, Nakashima Y, Ikeno H, et al. Inferior phrenic arteries: angiographic anatomy, variations, and catheterization techniques for transcatheter arterial chemoembolization. Jpn J Radiol. 2010;28(7):502\u201311. https:\/\/doi.org\/10.1007\/s11604-010-0456-7.","journal-title":"Jpn J Radiol"},{"issue":"4","key":"8170_CR7","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.2214\/AJR.09.3030","volume":"194","author":"HC Kim","year":"2010","unstructured":"Kim HC, Chung JW, Kim WH, An S, Seong NJ, Jae HJ, et al. Chemoembolization of the left inferior phrenic artery in patients with hepatocellular carcinoma: 9-year single-center experience. AJR Am J Roentgenol. 2010;194(4):1124\u201330. https:\/\/doi.org\/10.2214\/AJR.09.3030.","journal-title":"AJR Am J Roentgenol"},{"issue":"3","key":"8170_CR8","doi-asserted-by":"publisher","first-page":"339","DOI":"10.4103\/0019-509X.84941","volume":"48","author":"SB Paul","year":"2011","unstructured":"Paul SB, Gamanagatti SR, Mukund A, Abbas SZ, Acharya SK. Transarterial chemoembolization for hepatocellular carcinoma: significance of extrahepatic collateral supply. Indian J Cancer. 2011;48(3):339\u201344. https:\/\/doi.org\/10.4103\/0019-509X.84941.","journal-title":"Indian J Cancer"},{"issue":"9","key":"8170_CR9","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1016\/j.jvir.2009.05.030","volume":"20","author":"A Riaz","year":"2009","unstructured":"Riaz A, Lewandowski RJ, Kulik LM, Mulcahy MF, Sato KT, Ryu RK, et al. Complications following radioembolization with yttrium-90 microspheres: a comprehensive literature review. J Vasc Interv Radiol. 2009;20(9):1121\u201330. https:\/\/doi.org\/10.1016\/j.jvir.2009.05.030. quiz 1131.","journal-title":"J Vasc Interv Radiol"},{"issue":"10","key":"8170_CR10","doi-asserted-by":"publisher","first-page":"1294","DOI":"10.1016\/j.jvir.2012.07.009","volume":"23","author":"MC Burgmans","year":"2012","unstructured":"Burgmans MC, Kao YH, Irani FG, Dames EL, Teo TK, Goh AS, et al. Radioembolization with infusion of yttrium-90 microspheres into a right inferior phrenic artery with hepatic tumor supply is feasible and safe. J Vasc Interv Radiol. 2012;23(10):1294\u2013301. https:\/\/doi.org\/10.1016\/j.jvir.2012.07.009.","journal-title":"J Vasc Interv Radiol"},{"issue":"4","key":"8170_CR11","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1016\/j.jvir.2017.10.010","volume":"29","author":"HC Kim","year":"2018","unstructured":"Kim HC, Kim YJ, Paeng JC, Chung JW. Yttrium-90 Radioembolization of the Right Inferior Phrenic Artery in 20 Patients with Hepatocellular Carcinoma. J Vasc Interv Radiol. 2018;29(4):556\u201363. https:\/\/doi.org\/10.1016\/j.jvir.2017.10.010.","journal-title":"J Vasc Interv Radiol"},{"issue":"9","key":"8170_CR12","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1016\/j.jvir.2025.05.027","volume":"36","author":"HC Kim","year":"2025","unstructured":"Kim HC, Kim DH, Suh M, Paeng JC, Choi JW. High-Dose Radioembolization Limited by Lung Shunt for Hepatocellular Carcinoma Supplied by the Inferior Phrenic Artery. J Vasc Interv Radiol. 2025;36(9):1427\u2013e353. https:\/\/doi.org\/10.1016\/j.jvir.2025.05.027.","journal-title":"J Vasc Interv Radiol"},{"issue":"10","key":"8170_CR13","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.1016\/j.jvir.2011.06.007","volume":"22","author":"MH Abdelmaksoud","year":"2011","unstructured":"Abdelmaksoud MH, Louie JD, Kothary N, Hwang GL, Kuo WT, Hofmann LV, et al. Embolization of parasitized extrahepatic arteries to reestablish intrahepatic arterial supply to tumors before yttrium-90 radioembolization. J Vasc Interv Radiol. 2011;22(10):1355\u201362. https:\/\/doi.org\/10.1016\/j.jvir.2011.06.007.","journal-title":"J Vasc Interv Radiol"},{"issue":"7","key":"8170_CR14","doi-asserted-by":"publisher","first-page":"108784","DOI":"10.1016\/j.jvir.2026.108784","volume":"37","author":"GH Kim","year":"2026","unstructured":"Kim GH, Kim J, Ko E, Oh M, Sung C, Kim JH, et al. Effectiveness and Safety of Transarterial Radioembolization Following Inferior Phrenic Artery Glue Embolization for Flow Redistribution in Hepatocellular Carcinoma. J Vasc Interv Radiol. 2026;37(7):108784. https:\/\/doi.org\/10.1016\/j.jvir.2026.108784.","journal-title":"J Vasc Interv Radiol"},{"issue":"1","key":"8170_CR15","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1055\/s-0030-1247132","volume":"30","author":"R Lencioni","year":"2010","unstructured":"Lencioni R, Llovet JM. Modified RECIST (mRECIST) assessment for hepatocellular carcinoma. Semin Liver Dis. 2010;30(1):52\u201360. https:\/\/doi.org\/10.1055\/s-0030-1247132.","journal-title":"Semin Liver Dis"},{"issue":"3","key":"8170_CR16","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1007\/s00270-019-02362-y","volume":"43","author":"W Goh","year":"2020","unstructured":"Goh W, Leong S, Too CW, Cheng LT, Saffari SE, Lee RZ, et al. Catheter-Directed Computed Tomography Hepatic Angiography for Yttrium-90 Selective Internal Radiotherapy of Hepatocellular Carcinoma Reduces Prophylactic Embolization of Extrahepatic Vessels. Cardiovasc Intervent Radiol. 2020;43(3):478\u201387. https:\/\/doi.org\/10.1007\/s00270-019-02362-y.","journal-title":"Cardiovasc Intervent Radiol"},{"issue":"9","key":"8170_CR17","doi-asserted-by":"publisher","first-page":"1164","DOI":"10.1016\/j.jvir.2009.05.036","volume":"20","author":"YH So","year":"2009","unstructured":"So YH, Chung JW, Yin Y, Jae HJ, Jeon UB, Cho BH, et al. The right inferior phrenic artery: origin and proximal anatomy on digital subtraction angiography and thin-section helical computed tomography. J Vasc Interv Radiol. 2009;20(9):1164\u201371. https:\/\/doi.org\/10.1016\/j.jvir.2009.05.036.","journal-title":"J Vasc Interv Radiol"},{"issue":"5","key":"8170_CR18","doi-asserted-by":"publisher","first-page":"e84960","DOI":"10.7759\/cureus.84960","volume":"17","author":"G Sehgal","year":"2025","unstructured":"Sehgal G, Parihar A, Aggarwal N, Moonis M. Inferior Phrenic Artery Variations and a Novel Classification of Aortic and Non-aortic Origins: An Observational CT Angiographic Study. Cureus. 2025;17(5):e84960. https:\/\/doi.org\/10.7759\/cureus.84960.","journal-title":"Cureus"},{"issue":"12","key":"8170_CR19","doi-asserted-by":"publisher","first-page":"3776","DOI":"10.1007\/s00259-021-05340-0","volume":"48","author":"J Roosen","year":"2021","unstructured":"Roosen J, Klaassen N, Westlund Gotby L, Overduin CG, Verheij M, Konijnenberg MW, et al. To 1000 Gy and back again: a systematic review on dose-response evaluation in selective internal radiation therapy for primary and secondary liver cancer. Eur J Nucl Med Mol Imaging. 2021;48(12):3776\u201390. https:\/\/doi.org\/10.1007\/s00259-021-05340-0.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"1","key":"8170_CR20","doi-asserted-by":"publisher","first-page":"e220076","DOI":"10.1148\/rg.220076","volume":"43","author":"HC Kim","year":"2023","unstructured":"Kim HC, Miyayama S, Choi JW, Kim GM, Chung JW. Hepatocellular Carcinoma Supplied by the Inferior Phrenic Artery or Cystic Artery: Anatomic and Technical Considerations. Radiographics. 2023;43(1):e220076. https:\/\/doi.org\/10.1148\/rg.220076.","journal-title":"Radiographics"}],"container-title":["European Journal of Nuclear Medicine and Molecular Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00259-026-08170-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00259-026-08170-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00259-026-08170-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T01:50:24Z","timestamp":1789696224000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00259-026-08170-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,18]]},"references-count":20,"alternative-id":["8170"],"URL":"https:\/\/doi.org\/10.1007\/s00259-026-08170-0","relation":{},"ISSN":["1619-7070","1619-7089"],"issn-type":[{"value":"1619-7070","type":"print"},{"value":"1619-7089","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,18]]},"assertion":[{"value":"3 August 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This retrospective observational study was performed in accordance with the principles of the Declaration of Helsinki. Ethical approval was obtained from the Institutional Ethics Committee of Beijing Tsinghua Changgung Hospital (Ethics No. 26957\u20114\u201101). The requirement for written informed consent was formally waived by the ethics committee owing to the retrospective nature of the study and fully anonymized de\u2011identified patient data.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}