{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:53:22Z","timestamp":1787774002006,"version":"build-2784847793"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T00:00:00Z","timestamp":1543276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T00:00:00Z","timestamp":1543276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Abdom Radiol"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1007\/s00261-018-1838-z","type":"journal-article","created":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T04:13:39Z","timestamp":1543292019000},"page":"2941-2949","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Magnetic resonance imaging performed before and after preoperative chemoradiotherapy in rectal cancer: predictive factors of recurrence and prognostic significance of MR-detected extramural venous invasion"],"prefix":"10.1007","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4506-7036","authenticated-orcid":false,"given":"Francesco","family":"Prampolini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7524-8946","authenticated-orcid":false,"given":"Stefania","family":"Taschini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8142-3256","authenticated-orcid":false,"given":"Annarita","family":"Pecchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1184-7827","authenticated-orcid":false,"given":"Francesco","family":"Sani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6955-7139","authenticated-orcid":false,"given":"Andrea","family":"Spallanzani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7979-4795","authenticated-orcid":false,"given":"Fabio","family":"Gelsomino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1166-2961","authenticated-orcid":false,"given":"Shaniko","family":"Kaleci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5178-3063","authenticated-orcid":false,"given":"Pietro","family":"Torricelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,11,27]]},"reference":[{"issue":"7572","key":"1838_CR1","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1136\/bmj.38937.646400.55","volume":"333","author":"MERCURY Study Group","year":"2006","unstructured":"MERCURY Study Group (2006) Diagnostic accuracy of preoperative magnetic resonance imaging in predicting curative resection of rectal cancer: prospective observational study. BMJ 333(7572):779. \n                  https:\/\/doi.org\/10.1136\/bmj.38937.646400.55","journal-title":"BMJ"},{"key":"1838_CR2","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1148\/radiol.2431051825","volume":"243","author":"MERCURY Study Group","year":"2007","unstructured":"MERCURY Study Group (2007) Extramural depth of tumour invasion at thin-section MR in patients with rectal cancer: results of the MERCURY Study. Radiology 243:132\u2013139. \n                  https:\/\/doi.org\/10.1148\/radiol.2431051825","journal-title":"Radiology"},{"key":"1838_CR3","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1148\/radiol.13121361","volume":"268","author":"S Nougaret","year":"2013","unstructured":"Nougaret S, Reinhold C, Mikhael HW, et al. (2013) The use of MR imaging in treatment planning for patients with rectal carcinoma: have you checked the \u2018\u2018DISTANCE\u2019\u2019? Radiology 268:330\u2013344. \n                  https:\/\/doi.org\/10.1148\/radiol.13121361","journal-title":"Radiology"},{"issue":"12","key":"1838_CR4","doi-asserted-by":"publisher","first-page":"3278","DOI":"10.1245\/s10434-011-1776-2","volume":"18","author":"OC Shihab","year":"2011","unstructured":"Shihab OC, Taylor F, Salerno G, et al. (2011) MRI predictive factors for long-term outcomes of low rectal tumours. Annals of Surgical Oncology 18(12):3278\u20133284. \n                  https:\/\/doi.org\/10.1245\/s10434-011-1776-2","journal-title":"Annals of Surgical Oncology"},{"issue":"11","key":"1838_CR5","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1056\/NEJMoa060829","volume":"355","author":"JF Bosset","year":"2006","unstructured":"Bosset JF, Collette L, Calais G, et al. (2006) Chemotherapy with preoperative radiotherapy in rectal cancer. New England Journal of Medicine 355(11):1114\u20131123. \n                  https:\/\/doi.org\/10.1056\/NEJMoa060829","journal-title":"New England Journal of Medicine"},{"key":"1838_CR6","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1093\/annonc\/mdu029","volume":"25","author":"M Chand","year":"2014","unstructured":"Chand M, Bhangu A, Wotherspoon A, et al. (2014) EMVI-positive stage II rectal cancer has similar clinical outcomes as stage III disease following pre-operative chemoradiotherapy. Annals of Oncology 25:858\u2013863. \n                  https:\/\/doi.org\/10.1093\/annonc\/mdu029","journal-title":"Annals of Oncology"},{"key":"1838_CR7","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1136\/gut.51.1.65","volume":"51","author":"VC Petersen","year":"2002","unstructured":"Petersen VC, Baxter KJ, Love SB, Shepherd NA (2002) Identification of objective pathological prognostic determinants and models of prognosis in Dukes\u2019 B colon cancer. Gut 51:65\u201369","journal-title":"Gut"},{"issue":"6","key":"1838_CR8","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1097\/SLA.0000000000000229","volume":"259","author":"CS Roxburgh","year":"2014","unstructured":"Roxburgh CS, McMillan DC, Richards CH, et al. (2014) The clinical utility of the combination of T stage and venous invasion to predict survival in patients undergoing surgery for colorectal cancer. Annals of Surgery 259(6):1156\u20131165. \n                  https:\/\/doi.org\/10.1097\/SLA.0000000000000229","journal-title":"Annals of Surgery"},{"key":"1838_CR9","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1016\/j.amjsurg.2013.02.010","volume":"206","author":"JW Huh","year":"2013","unstructured":"Huh JW, Lee JH, Kim HR, Kim YJ (2013) Prognostic significance of lymphovascular or perineural invasion in patients with locally advanced colorectal cancer. American Journal of Surgery 206:758\u2013763. \n                  https:\/\/doi.org\/10.1016\/j.amjsurg.2013.02.010","journal-title":"American Journal of Surgery"},{"key":"1838_CR10","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.1002\/bjs.7254","volume":"97","author":"PG Horgan","year":"2010","unstructured":"Horgan PG, McMillan DC (2010) Surgeons and selection of adjuvant therapy for node-negative colonic cancer. British Journal of Surgery 97:1459\u20131460. \n                  https:\/\/doi.org\/10.1002\/bjs.7254","journal-title":"British Journal of Surgery"},{"key":"1838_CR11","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.critrevonc.2013.11.004","volume":"90","author":"HC Van Wyk","year":"2014","unstructured":"Van Wyk HC, Roxburgh CS, Horgan PG, Foulis AF, McMillan DC (2014) The detection and role of lymphatic and blood vessel invasion in predicting survival in patients with node negative operable primary colorectal cancer. Critical Reviews in Oncology Hematology 90:77\u201390. \n                  https:\/\/doi.org\/10.1016\/j.critrevonc.2013.11.004","journal-title":"Critical Reviews in Oncology Hematology"},{"key":"1838_CR12","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1111\/j.1365-2559.1981.tb01774.x","volume":"5","author":"IC Talbot","year":"1981","unstructured":"Talbot IC, Ritchie S, Leighton M, et al. (1981) Invasion of veins by carcinoma of rectum: method of detection, histological features and significance. Histopathology 5:141\u2013163","journal-title":"Histopathology"},{"key":"1838_CR13","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1002\/bjs.1800670619","volume":"67","author":"IC Talbot","year":"1980","unstructured":"Talbot IC, Ritchie S, Leighton MH, et al. (1980) The clinical significance of invasion of veins by rectal cancer. British Journal of Surgery 67:439\u2013442","journal-title":"British Journal of Surgery"},{"key":"1838_CR14","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1016\/j.clinimag.2016.01.007","volume":"40","author":"L Liu","year":"2016","unstructured":"Liu L, Liu M, Yang Z, He W, Wang Z (2016) Correlation of MRI-detected extramural vascular invasion with regional lymph node metastasis in rectal cancer. Clinical Imaging 40:456\u2013460. \n                  https:\/\/doi.org\/10.1016\/j.clinimag.2016.01.007","journal-title":"Clinical Imaging"},{"key":"1838_CR15","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1002\/cncr.26310","volume":"118","author":"J Betge","year":"2012","unstructured":"Betge J, Pollheimer MJ, Lindtner RA, et al. (2012) Intramural and extramural vascular invasion in colorectal cancer: prognostic significance and quality of pathology reporting. Cancer 118:628\u2013638. \n                  https:\/\/doi.org\/10.1002\/cncr.26310","journal-title":"Cancer"},{"key":"1838_CR16","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1002\/bjs.5917","volume":"95","author":"N Smith","year":"2008","unstructured":"Smith N, Barbachano Y, Norman AR, et al. (2008) Prognostic significance of magnetic resonance imaging-detected extramural vascular invasion in rectal cancer. British Journal of Surgery 95:229\u2013236","journal-title":"British Journal of Surgery"},{"key":"1838_CR17","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1080\/02841860701697720","volume":"47","author":"N Smith","year":"2008","unstructured":"Smith N, Brown G (2008) Preoperative staging of rectal cancer. Acta Oncologica 47:20\u201331. \n                  https:\/\/doi.org\/10.1080\/02841860701697720","journal-title":"Acta Oncologica"},{"key":"1838_CR18","doi-asserted-by":"publisher","first-page":"e0144987","DOI":"10.1371\/journal.pone.0144987","volume":"10","author":"D McClelland","year":"2015","unstructured":"McClelland D, Murray GI (2015) A comprehensive study of extramural venous invasion in colorectal cancer. PLoS ONE 10:e0144987. \n                  https:\/\/doi.org\/10.1371\/journal.pone.0144987","journal-title":"PLoS ONE"},{"key":"1838_CR19","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1136\/jcp.2009.065615","volume":"62","author":"CJ Howlett","year":"2009","unstructured":"Howlett CJ, Tweedie EJ, Driman DK (2009) Use of an elastic stain to show venous invasion in colorectal carcinoma: a simple technique for detection of an important prognostic factor. Journal of Clinical Pathology 62:1021\u20131025. \n                  https:\/\/doi.org\/10.1136\/jcp.2009.065615","journal-title":"Journal of Clinical Pathology"},{"key":"1838_CR20","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1136\/jcp.2003.015826","volume":"57","author":"DG Vass","year":"2004","unstructured":"Vass DG, Ainsworth R, Anderson JH, Murray D, Foulis AK (2004) The value of an elastic tissue stain in detecting venous invasion in colorectal cancer. Journal of Clinical Pathology 57:769\u2013772. \n                  https:\/\/doi.org\/10.1136\/jcp.2003.015826","journal-title":"Journal of Clinical Pathology"},{"key":"1838_CR21","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.2214\/AJR.08.1298","volume":"191","author":"NJ Smith","year":"2008","unstructured":"Smith NJ, Shihab O, Arnaout A, Swift RI, Brown G (2008) MRI for detection of extramural vascular invasion in rectal cancer. AJR. American Journal of Roentgenology 191:1517\u20131522. \n                  https:\/\/doi.org\/10.2214\/AJR.08.1298","journal-title":"AJR. American Journal of Roentgenology"},{"key":"1838_CR22","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1002\/bjs.4034","volume":"90","author":"G Brown","year":"2003","unstructured":"Brown G, Radcliffe AG, Newcombe RG, et al. (2003) Preoperative assessment of prognostic factors in rectal cancer using high-resolution magnetic resonance imaging. British Journal of Surgery 90:355\u2013364. \n                  https:\/\/doi.org\/10.1002\/bjs.4034","journal-title":"British Journal of Surgery"},{"key":"1838_CR23","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1097\/SLA.0000000000000848","volume":"261","author":"M Chand","year":"2015","unstructured":"Chand M, Evans J, Swift RI, et al. (2015) The prognostic significance of post chemoradiotherapy high-resolution MRI and histopathology detected extramural venous invasion in rectal cancer. Annals of Surgery 261:473\u2013479. \n                  https:\/\/doi.org\/10.1097\/SLA.0000000000000848","journal-title":"Annals of Surgery"},{"key":"1838_CR24","doi-asserted-by":"publisher","unstructured":"MERCURY Study Group, Shihab OC, Taylor F, et al. (2011) Relevance of magnetic resonance imaging-detected pelvic sidewall lymph node involvement in rectal cancer. Br J Surg 98(12):1798\u20131804. \n                  https:\/\/doi.org\/10.1002\/bjs.7662","DOI":"10.1002\/bjs.7662"},{"issue":"2","key":"1838_CR25","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1148\/radiol.2272011747","volume":"227","author":"G Brown","year":"2003","unstructured":"Brown G, Richards CJ, Bourne MW, et al. (2003) Morphologic predictors of lymph node status in rectal cancer with use of high-spatial resolution MR imaging with histopathologic comparison. Radiology 227(2):371\u2013377. \n                  https:\/\/doi.org\/10.1148\/radiol.2272011747","journal-title":"Radiology"},{"issue":"1","key":"1838_CR26","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.ejrad.2003.12.005","volume":"52","author":"JH Kim","year":"2004","unstructured":"Kim JH, Beets GL, Kim MJ, Kessels AG, Beets-Tan RG (2004) High-resolution MR imaging for nodal staging in rectal cancer: are there any criteria in addition to the size? European Journal of Radiology 52(1):78\u201383. \n                  https:\/\/doi.org\/10.1016\/j.ejrad.2003.12.005","journal-title":"European Journal of Radiology"},{"issue":"6","key":"1838_CR27","doi-asserted-by":"publisher","first-page":"872","DOI":"10.1002\/bjs.7458","volume":"98","author":"FG Taylor","year":"2011","unstructured":"Taylor FG, Quirke P, Heald RJ, et al. (2011) One millimetre is the safe cut-off for magnetic resonance imaging prediction of surgical margin status in rectal cancer. British Journal of Surgery 98(6):872\u2013879. \n                  https:\/\/doi.org\/10.1002\/bjs.7458","journal-title":"British Journal of Surgery"},{"key":"1838_CR28","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1038\/bjc.2013.603","volume":"110","author":"M Chand","year":"2014","unstructured":"Chand M, Swift RI, Tekkis PP, Chau I, Brown G (2014) Extramural venous invasion is a potential imaging predictive biomarker of neoadjuvant treatment in rectal cancer. British Journal of Cancer 110:19\u201325. \n                  https:\/\/doi.org\/10.1038\/bjc.2013.603","journal-title":"British Journal of Cancer"},{"issue":"4","key":"1838_CR29","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1097\/SLA.0b013e31820b8d52","volume":"253","author":"FG Taylor","year":"2011","unstructured":"Taylor FG, Quirke P, Heald RJ, et al. (2011) Preoperative high-resolution magnetic resonance imaging can identify good prognosis stage I, II, and III rectal cancer best managed by surgery alone: a prospective, multicenter. European study. Ann Surg 253(4):711\u2013719. \n                  https:\/\/doi.org\/10.1097\/SLA.0b013e31820b8d52","journal-title":"European study. Ann Surg"},{"issue":"suppl_4","key":"1838_CR30","doi-asserted-by":"publisher","first-page":"iv22-iv40","DOI":"10.1093\/annonc\/mdx224","volume":"28","author":"R Glynne-Jones","year":"2017","unstructured":"Glynne-Jones R, Wyrwicz L, Tiret E, et al. (2017) Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 28(suppl_4):iv22-iv40. \n                  https:\/\/doi.org\/10.1093\/annonc\/mdx224","journal-title":"Ann Oncol"},{"issue":"2","key":"1838_CR31","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1007\/s00330-017-4978-6","volume":"28","author":"ES Lee","year":"2018","unstructured":"Lee ES, Kim MJ, Park SC, et al. (2018) Magnetic Resonance Imaging-Detected Extramural Venous Invasion in Rectal Cancer before and after Preoperative Chemoradiotherapy: Diagnostic Performance and Prognostic Significance. Eur Radiol 28(2):496\u2013505. \n                  https:\/\/doi.org\/10.1007\/s00330-017-4978-6","journal-title":"Eur Radiol"},{"issue":"28","key":"1838_CR32","doi-asserted-by":"publisher","first-page":"3753","DOI":"10.1200\/JCO.2011.34.9068","volume":"29","author":"UB Patel","year":"2011","unstructured":"Patel UB, Taylor F, Blomqvist L, et al. (2011) Magnetic resonance imaging-detected tumor response for locally advanced rectal cancer predicts survival outcomes: MERCURY experience. J Clin Oncol 29(28):3753\u20133760. \n                  https:\/\/doi.org\/10.1200\/JCO.2011.34.9068","journal-title":"J Clin Oncol"}],"container-title":["Abdominal Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00261-018-1838-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00261-018-1838-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00261-018-1838-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T15:04:18Z","timestamp":1598627058000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00261-018-1838-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,27]]},"references-count":32,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["1838"],"URL":"https:\/\/doi.org\/10.1007\/s00261-018-1838-z","relation":{},"ISSN":["2366-004X","2366-0058"],"issn-type":[{"value":"2366-004X","type":"print"},{"value":"2366-0058","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,27]]},"assertion":[{"value":"27 November 2018","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}