{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T06:16:37Z","timestamp":1769580997101,"version":"3.49.0"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2021,3,5]],"date-time":"2021-03-05T00:00:00Z","timestamp":1614902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,3,5]],"date-time":"2021-03-05T00:00:00Z","timestamp":1614902400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Medizinische Hochschule Hannover (MHH)"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Abdom Radiol"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>To evaluate the feasibility and effect of an approach to adrenal venous sampling (AVS) analysis by combining established selective cortisol and aldosterone indices with the acquisition of a collimated C-arm CT(CACT<jats:sub>Coll<\/jats:sub>).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Overall, 107 consecutive patients (45f,62\u00a0m; 54\u2009\u00b1\u200910\u00a0years) undergoing 111 AVS procedures without hormonal stimulation from 7\/13 to 2\/20 in a single institution were retrospectively analysed. Hormone levels were measured in sequential samples of the suspected adrenal veins and right iliac vein, and selectivity indices (SI) computed. Stand-alone SI<jats:sub>Cortisol<\/jats:sub> and\/or SI<jats:sub>Aldosterone<\/jats:sub>\u2009\u2265\u20092.0 as well as SI<jats:sub>Cortisol<\/jats:sub> and\/or SI<jats:sub>Aldosterone<\/jats:sub>\u2009\u2265\u20091.1 combined with positive right-sided CACT<jats:sub>Coll<\/jats:sub> of the adrenals (<jats:italic>n<\/jats:italic>\u2009=\u200980; opacified right adrenal vein) were defined as a successful AVS procedure. Radiation exposure of CACT was measured via dose area product (DAP) and weighed against an age-\/weight-matched cohort (<jats:italic>n<\/jats:italic>\u2009=\u200966).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Preliminary success rates (SI<jats:sub>Cortisol<\/jats:sub> and\/or SI<jats:sub>Aldosterone<\/jats:sub>\u2009\u2265\u20092.0) were 99.1% (left) and 72.1% (right). These could be significantly increased to a 90.1% success rate on the right, by combining an adjusted SI of 1.1 with a positive CACT<jats:sub>Coll<\/jats:sub> proving the correct sampling position. Sensitivity for stand-alone collimated CACT (CACT<jats:sub>Coll<\/jats:sub>) was 0.93, with 74\/80 acquired CACT<jats:sub>Coll<\/jats:sub> confirming selective cannulation by adrenal vein enhancement. Mean DAP<jats:sub>Coll_CACT<\/jats:sub> measured 2414\u2009\u00b1\u2009958 \u03bcGyxm<jats:sup>2<\/jats:sup>, while mean DAP<jats:sub>Full-FOV_CACT<\/jats:sub> in the matched cohort measured 8766\u2009\u00b1\u20091956 \u03bcGyxm<jats:sup>2<\/jats:sup> (p\u2009&lt;\u20090.001).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Collimated CACT in AVS procedures is feasible and leads to a significant increase in success rates of (right-sided) selective cannulation and may in combination with adapted hormone indices, offer a successful alternative to previously published AVS analysis algorithms with lower radiation exposure compared to a full-FOV CACT.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00261-021-03003-0","type":"journal-article","created":{"date-parts":[[2021,3,5]],"date-time":"2021-03-05T17:03:01Z","timestamp":1614963781000},"page":"3471-3481","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Adrenal venous sampling in primary hyperaldosteronism: correlation of hormone indices and collimated C-arm CT findings"],"prefix":"10.1007","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9568-6233","authenticated-orcid":false,"given":"L. 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