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HPI, a parameter calculated by a commercially available CT liver perfusion analysis software that is based on the double maximum slope model, using time attenuation curve to determine perfusion, was correlated with the degree of esophageal varices diagnosed at endoscopy and the number of bleeding events.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Eta correlation coefficient for HPI\/presence of esophageal varices was very weak (0.083). Spearman-Rho for HPI\/grading of esophageal varices was very weak (0.037 (<jats:italic>p<\/jats:italic>\u2009=\u20090.804)). Kendall-Tau-b for HPI\/grading of esophageal varices was very weak (0.027 (<jats:italic>p<\/jats:italic>\u2009=\u20090.807)). ANOVA and Bonferroni post-hoc-tests showed no significant difference of HPI between different grades of esophageal varices (<jats:italic>F<\/jats:italic> (3, 62)\u2009=\u20091.676, <jats:italic>p<\/jats:italic>\u2009=\u20090.186). Eta correlation coefficient for HPI\/bleeding event was very weak (0.126).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The stratification of the degree of esophageal varices and the related bleeding risk by correlation with the HPI as a surrogate parameter for portal venous hypertension was not possible for patients with liver cirrhosis in Child\u2013Pugh class A and B.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Graphic abstract<\/jats:title>\n                \n              <\/jats:sec>","DOI":"10.1007\/s00261-021-03259-6","type":"journal-article","created":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T17:02:55Z","timestamp":1630083775000},"page":"5586-5597","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["CT hepatic arterial perfusion index does not allow stratification of the degree of esophageal varices and bleeding risk in cirrhotic patients in Child\u2013Pugh classes A and B"],"prefix":"10.1007","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4800-8381","authenticated-orcid":false,"given":"Felix","family":"Peisen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaspar","family":"Ekert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Bitzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans","family":"B\u00f6sm\u00fcller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Fritz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marius","family":"Horger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,8,27]]},"reference":[{"issue":"2","key":"3259_CR1","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.amjsurg.2011.02.007","volume":"203","author":"MJ Orloff","year":"2012","unstructured":"Orloff MJ, Isenberg JI, Wheeler HO, Haynes KS, Jinich-Brook H, Rapier R, Vaida F, Hye RJ, Orloff SL (2012) A randomized controlled trial of emergency treatment of bleeding esophageal varices in cirrhosis for hepatocellular carcinoma. 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