{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T17:17:39Z","timestamp":1762881459630,"version":"3.45.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T00:00:00Z","timestamp":1747267200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T00:00:00Z","timestamp":1747267200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"GE Healthcare Ltd."}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Abdom Radiol"],"DOI":"10.1007\/s00261-025-04971-3","type":"journal-article","created":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T23:13:20Z","timestamp":1747264400000},"page":"5637-5648","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Low-osmolar contrast tagging in minimally cathartic CT colonography for colorectal cancer screening: an observational study"],"prefix":"10.1007","volume":"50","author":[{"given":"Anna","family":"Eligulashvili","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zina","family":"Ricci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devaraju","family":"Kanmaniraja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Rezko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenny Q.","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judy","family":"Yee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,5,15]]},"reference":[{"key":"4971_CR1","unstructured":"American Cancer Society. Cancer Facts & Figs. 2025. (Atlanta, GA, 2025)."},{"key":"4971_CR2","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1055\/s-0036-1584091","volume":"29","author":"MB Huck","year":"2016","unstructured":"Huck, M. B. & Bohl, J. L. Colonic Polyps: Diagnosis and Surveillance. Clin Colon Rectal Surg 29, 296\u2013305 (2016). https:\/\/doi.org\/10.1055\/s-0036-1584091","journal-title":"Clin Colon Rectal Surg"},{"key":"4971_CR3","doi-asserted-by":"publisher","first-page":"1978","DOI":"10.1001\/jama.2021.4417","volume":"325","author":"JS Lin","year":"2021","unstructured":"Lin, J. S., Perdue, L. A., Henrikson, N. B., Bean, S. I. & Blasi, P. R. Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. Jama 325, 1978\u20131998 (2021). https:\/\/doi.org\/10.1001\/jama.2021.4417","journal-title":"Jama"},{"key":"4971_CR4","doi-asserted-by":"publisher","first-page":"1554","DOI":"10.1158\/1055-9965.Epi-20-1809","volume":"30","author":"JA Shapiro","year":"2021","unstructured":"Shapiro, J. A., Soman, A. V., Berkowitz, Z., Fedewa, S. A., Sabatino, S. A., de Moor, J. S., Clarke, T. C., Doria-Rose, V. P., Breslau, E. S., Jemal, A. & Nadel, M. R. Screening for Colorectal Cancer in the United States: Correlates and Time Trends by Type of Test. Cancer Epidemiol Biomarkers Prev 30, 1554\u20131565 (2021). https:\/\/doi.org\/10.1158\/1055-9965.Epi-20-1809","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"4971_CR5","doi-asserted-by":"publisher","first-page":"e24916","DOI":"10.7759\/cureus.24916","volume":"14","author":"M Kadari","year":"2022","unstructured":"Kadari, M., Subhan, M., Saji Parel, N., Krishna, P. V., Gupta, A., Uthayaseelan, K., Uthayaseelan, K. & Sunkara, N. CT Colonography and Colorectal Carcinoma: Current Trends and Emerging Developments. Cureus 14, e24916 (2022). https:\/\/doi.org\/10.7759\/cureus.24916","journal-title":"Cureus"},{"key":"4971_CR6","doi-asserted-by":"publisher","first-page":"1202","DOI":"10.2214\/ajr.15.15373","volume":"206","author":"B Johnson","year":"2016","unstructured":"Johnson, B., Hinshaw, J. L., Robbins, J. B. & Pickhardt, P. J. Objective and Subjective Intrapatient Comparison of Iohexol Versus Diatrizoate for Bowel Preparation Quality at CT Colonography. AJR Am J Roentgenol 206, 1202\u20131207 (2016). https:\/\/doi.org\/10.2214\/ajr.15.15373","journal-title":"AJR Am J Roentgenol"},{"key":"4971_CR7","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1055\/a-1258-4819","volume":"52","author":"C Spada","year":"2020","unstructured":"Spada, C., Hassan, C., Bellini, D., Burling, D., Cappello, G., Carretero, C., Dekker, E., Eliakim, R., de Haan, M., Kaminski, M. F., Koulaouzidis, A., Laghi, A., Lefere, P., Mang, T., Milluzzo, S. M., Morrin, M., McNamara, D., Neri, E., Pecere, S., Pioche, M., Plumb, A., Rondonotti, E., Spaander, M. C., Taylor, S., Fernandez-Urien, I., van Hooft, J. E., Stoker, J. & Regge, D. Imaging alternatives to colonoscopy: CT colonography and colon capsule. European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastrointestinal and Abdominal Radiology (ESGAR) Guideline - Update 2020. Endoscopy 52, 1127\u20131141 (2020). https:\/\/doi.org\/10.1055\/a-1258-4819","journal-title":"Endoscopy"},{"key":"4971_CR8","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1053\/j.ro.2020.07.007","volume":"56","author":"ZJ Ricci","year":"2021","unstructured":"Ricci, Z. J., Kobi, M., Flusberg, M. & Yee, J. CT Colonography in Review With Tips and Tricks to Improve Performance. Semin Roentgenol 56, 140\u2013151 (2021). https:\/\/doi.org\/10.1053\/j.ro.2020.07.007","journal-title":"Semin Roentgenol"},{"key":"4971_CR9","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1186\/s12880-020-00446-7","volume":"20","author":"J Sha","year":"2020","unstructured":"Sha, J., Chen, J., Lv, X., Liu, S., Chen, R. & Zhang, Z. Computed tomography colonography versus colonoscopy for detection of colorectal cancer: a diagnostic performance study. BMC Med Imaging 20, 51 (2020). https:\/\/doi.org\/10.1186\/s12880-020-00446-7","journal-title":"BMC Med Imaging"},{"key":"4971_CR10","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1177\/0846537119892881","volume":"71","author":"M Schonberger","year":"2020","unstructured":"Schonberger, M., Lefere, P. & Dachman, A. H. Pearls and Pitfalls of Interpretation in CT Colonography. Can Assoc Radiol J 71, 140\u2013148 (2020). https:\/\/doi.org\/10.1177\/0846537119892881","journal-title":"Can Assoc Radiol J"},{"key":"4971_CR11","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/s13244-020-00848-9","volume":"11","author":"T Mang","year":"2020","unstructured":"Mang, T., Br\u00e4uer, C., Gryspeerdt, S., Scharitzer, M., Ringl, H. & Lefere, P. Electronic cleansing of tagged residue in CT colonography: what radiologists need to know. Insights Imaging 11, 47 (2020). https:\/\/doi.org\/10.1186\/s13244-020-00848-9","journal-title":"Insights Imaging"},{"key":"4971_CR12","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-024-04504-4","author":"N Nakrour","year":"2024","unstructured":"Nakrour, N., Neibling, J. E., Pathak, A. & Carbo, A. Gastrointestinal pharmacoradiology, an updated review of medications and gastrointestinal contrasts in abdominal imaging. Abdom Radiol (NY) (2024). https:\/\/doi.org\/10.1007\/s00261-024-04504-4","journal-title":"Abdom Radiol (NY)"},{"key":"4971_CR13","doi-asserted-by":"publisher","first-page":"e587","DOI":"10.1002\/ams2.587","volume":"7","author":"JWV Tong","year":"2020","unstructured":"Tong, J. W. V., Lingam, P. & Shelat, V. G. Adhesive small bowel obstruction - an update. Acute Med Surg 7, e587 (2020). https:\/\/doi.org\/10.1002\/ams2.587","journal-title":"Acute Med Surg"},{"key":"4971_CR14","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1097\/rct.0000000000001526","volume":"48","author":"Y Chen","year":"2024","unstructured":"Chen, Y., Feng, L., Huang, Z., Zou, W., Luo, G., Dai, G., Zhao, W., Cai, W. & Luo, M. Comparison of Diatrizoate and Iohexol for Patient Acceptance and Fecal-Tagging Performance in Noncathartic CT Colonography. J Comput Assist Tomogr 48, 55\u201363 (2024). https:\/\/doi.org\/10.1097\/rct.0000000000001526","journal-title":"J Comput Assist Tomogr"},{"key":"4971_CR15","doi-asserted-by":"publisher","unstructured":"Rognstad \u00d8, B., Botteri, E., Hoff, G., Bretthauer, M., Gulichsen, E., Frigstad, S. O., Holme, \u00d8. & Randel, K. R. Adverse events after colonoscopy in a randomised colorectal cancer screening trial. BMJ Open Gastroenterol 11 (2024). https:\/\/doi.org\/10.1136\/bmjgast-2024-001471","DOI":"10.1136\/bmjgast-2024-001471"},{"key":"4971_CR16","doi-asserted-by":"publisher","first-page":"529","DOI":"10.31557\/apjcp.2024.25.2.529","volume":"25","author":"OP N","year":"2024","unstructured":"N, O. P., Supachai, K., Boonyapibal, A., Suebwongdit, C., Panaiem, S. & Sirisophawadee, T. Bowel Preparation Burden, Rectal Pain and Abdominal Discomfort: Perspective of Participants Undergoing CT Colonography and Colonoscopy. Asian Pac J Cancer Prev 25, 529\u2013536 (2024). https:\/\/doi.org\/10.31557\/apjcp.2024.25.2.529","journal-title":"Asian Pac J Cancer Prev"},{"key":"4971_CR17","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.1016\/j.cgh.2019.10.044","volume":"18","author":"M Spadaccini","year":"2020","unstructured":"Spadaccini, M., Frazzoni, L., Vanella, G., East, J., Radaelli, F., Spada, C., Fuccio, L., Benamouzig, R., Bisschops, R., Bretthauer, M., Dekker, E., Dinis-Ribeiro, M., Ferlitsch, M., Gralnek, I., Jover, R., Kaminski, M. F., Pellis\u00e9, M., Triantafyllou, K., Van Hooft, J. E., Dumonceau, J. M., Marmo, C., Alfieri, S., Chandrasekar, V. T., Sharma, P., Rex, D. K., Repici, A. & Hassan, C. Efficacy and Tolerability of High- vs Low-Volume Split-Dose Bowel Cleansing Regimens for Colonoscopy: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol 18, 1454\u20131465.e1414 (2020). https:\/\/doi.org\/10.1016\/j.cgh.2019.10.044","journal-title":"Clin Gastroenterol Hepatol"},{"key":"4971_CR18","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1007\/s11604-018-0800-x","volume":"37","author":"K Mitsuzaki","year":"2019","unstructured":"Mitsuzaki, K., Iinuma, G., Morimoto, T., Miyake, M. & Tomimatsu, H. Computed tomographic colonography with a reduced dose of laxative using a novel barium sulfate contrast agent in Japan. Jpn J Radiol 37, 245\u2013254 (2019). https:\/\/doi.org\/10.1007\/s11604-018-0800-x","journal-title":"Jpn J Radiol"},{"key":"4971_CR19","doi-asserted-by":"publisher","first-page":"1836","DOI":"10.2214\/ajr.184.6.01841836","volume":"184","author":"P Lefere","year":"2005","unstructured":"Lefere, P., Gryspeerdt, S., Marrannes, J., Baekelandt, M. & Van Holsbeeck, B. CT colonography after fecal tagging with a reduced cathartic cleansing and a reduced volume of barium. AJR Am J Roentgenol 184, 1836\u20131842 (2005). https:\/\/doi.org\/10.2214\/ajr.184.6.01841836","journal-title":"AJR Am J Roentgenol"},{"key":"4971_CR20","doi-asserted-by":"publisher","first-page":"5184","DOI":"10.1007\/s00330-023-09471-w","volume":"33","author":"M Rengo","year":"2023","unstructured":"Rengo, M., Tiberia, F., Vicini, S., Bellini, D., Celestre, M., Trionfera, G., Laghi, A. & Carbone, I. CT colonography: can we achieve an adequate bowel preparation without diet restriction? Eur Radiol 33, 5184\u20135192 (2023). https:\/\/doi.org\/10.1007\/s00330-023-09471-w","journal-title":"Eur Radiol"},{"key":"4971_CR21","unstructured":"Centers for Medicare & Medicaid Services. Vol. 89 (ed Department of Health and Human Services) 97710\u201399057 (Federal Register, 2024)."},{"key":"4971_CR22","doi-asserted-by":"publisher","first-page":"E907-e913","DOI":"10.1055\/a-0624-2266","volume":"6","author":"P Kump","year":"2018","unstructured":"Kump, P., Hassan, C., Spada, C., Brownstone, E., Datz, C., Haefner, M., Renner, F., Schoefl, R. & Schreiber, F. Efficacy and safety of a new low-volume PEG with citrate and simethicone bowel preparation for colonoscopy (Clensia): a multicenter randomized observer-blind clinical trial vs. a low-volume PEG with ascorbic acid (PEG-ASC). Endosc Int Open 6, E907-e913 (2018). https:\/\/doi.org\/10.1055\/a-0624-2266","journal-title":"Endosc Int Open"},{"key":"4971_CR23","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.3748\/wjg.v29.i11.1685","volume":"29","author":"E Shahini","year":"2023","unstructured":"Shahini, E., Sinagra, E., Vitello, A., Ranaldo, R., Contaldo, A., Facciorusso, A. & Maida, M. Factors affecting the quality of bowel preparation for colonoscopy in hard-to-prepare patients: Evidence from the literature. World J Gastroenterol 29, 1685\u20131707 (2023). https:\/\/doi.org\/10.3748\/wjg.v29.i11.1685","journal-title":"World J Gastroenterol"},{"key":"4971_CR24","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1016\/j.jss.2024.07.058","volume":"302","author":"D Kim","year":"2024","unstructured":"Kim, D., Wang, J., Gupta, A., Wlodarczyk, J., Williams, B., Cologne, K., Lee, S. & Koller, S. Patient Compliance With Bowel Preparation for Elective Colorectal Surgery. J Surg Res 302, 697\u2013705 (2024). https:\/\/doi.org\/10.1016\/j.jss.2024.07.058","journal-title":"J Surg Res"},{"key":"4971_CR25","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.1007\/s00330-014-3568-0","volume":"25","author":"B Kim","year":"2015","unstructured":"Kim, B., Park, S. H., Hong, G. S., Lee, J. H., Lee, J. S., Kim, H. J., Kim, A. Y. & Ha, H. K. Iohexol versus diatrizoate for fecal\/fluid tagging during CT colonography performed with cathartic preparation: comparison of examination quality. Eur Radiol 25, 1561\u20131569 (2015). https:\/\/doi.org\/10.1007\/s00330-014-3568-0","journal-title":"Eur Radiol"},{"key":"4971_CR26","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1148\/radiol.2016151608","volume":"280","author":"DH Kim","year":"2016","unstructured":"Kim, D. H., Matkowskyj, K. A., Lubner, M. G., Hinshaw, J. L., Munoz Del Rio, A., Pooler, B. D., Weiss, J. M. & Pickhardt, P. J. Serrated Polyps at CT Colonography: Prevalence and Characteristics of the Serrated Polyp Spectrum. Radiology 280, 455\u2013463 (2016). https:\/\/doi.org\/10.1148\/radiol.2016151608","journal-title":"Radiology"}],"container-title":["Abdominal Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00261-025-04971-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00261-025-04971-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00261-025-04971-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T17:12:08Z","timestamp":1762881128000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00261-025-04971-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,15]]},"references-count":26,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4971"],"URL":"https:\/\/doi.org\/10.1007\/s00261-025-04971-3","relation":{},"ISSN":["2366-0058"],"issn-type":[{"type":"electronic","value":"2366-0058"}],"subject":[],"published":{"date-parts":[[2025,5,15]]},"assertion":[{"value":"18 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 April 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 April 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 May 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by an IRB.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Each study participant provided written informed consent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent of participant"}},{"value":"The authors have no employments to disclose.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Employment"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}