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The following authors disclose conflicts of interest outside the submitted work: V.P. none. M.R. served as a consultant for Bayer, Sirtex and Guerbet and received lecture fees from Sirtex, Canon, Guerbet, General Electrics, and Terumo. L.M. none. L.E. received speaker fees from AbbVie, Gilead and Echosens. P.-E.R. has received research funding from Terrafirma and acted as consultant for Mursla, Genfit, Boehringer Ingelheim, Cook, AstraZeneca, Jazz and Abbelight, and received speaker fees from AbbVie, Jazz and Genfit. Financial support: No financial support specific to this study was received.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}