{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T14:19:22Z","timestamp":1706019562885},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2004,8,18]],"date-time":"2004-08-18T00:00:00Z","timestamp":1092787200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer Immunol Immunother"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1007\/s00262-004-0571-3","type":"journal-article","created":{"date-parts":[[2004,8,17]],"date-time":"2004-08-17T17:06:02Z","timestamp":1092762362000},"page":"67-77","source":"Crossref","is-referenced-by-count":29,"title":["Generation of potent anti-tumor immunity in mice by interleukin-12-secreting dendritic cells"],"prefix":"10.1007","volume":"54","author":[{"given":"Katharina Gabriele","family":"H\ufffdttner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine Konstanze","family":"Breuer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petra","family":"Paul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Otto","family":"Majdic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Heitger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Felzmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2004,8,18]]},"reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1182\/blood-2002-04-1088","volume":"101","author":"Aliberti","year":"2003","unstructured":"Aliberti J, Schulz O, Pennington DJ, Tsujimura H, Reis e Sousa C, Ozato K, Sher A (2003) Essential role for ICSBP in the in vivo development of murine CD8alpha + dendritic cells. Blood 101:305","journal-title":"Blood"},{"key":"CR2","first-page":"3688","volume":"63","author":"Camporeale","year":"2003","unstructured":"Camporeale A, Boni A, Iezzi G, Degl?Innocenti E, Grioni M, Mondino A, Bellone M (2003) Critical impact of the kinetics of dendritic cells activation on the in vivo induction of tumor-specific T lymphocytes. Cancer Res 63:3688","journal-title":"Cancer Res"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1084\/jem.171.2.377","volume":"171","author":"Carbone","year":"1990","unstructured":"Carbone FR, Bevan MJ (1990) Class I-restricted processing and presentation of exogenous cell-associated antigen in vivo. J Exp Med 171:377","journal-title":"J Exp Med"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1128\/AAC.33.9.1428","volume":"33","author":"Danner","year":"1989","unstructured":"Danner R, Joiner K, Rubin M, Patterson W, Johnson N, Ayers K, Parrillo J (1989) Purification, toxicity, and antiendotoxin activity of polymyxin B nonapeptide. Antimicrob Agents Chemother 33:1428","journal-title":"Antimicrob Agents Chemother"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1038\/4151043a","volume":"425","author":"delHoyo","year":"2002","unstructured":"delHoyo GM, Martin P, Vargas HH, Ruiz S, Arias CF, Ardavin C (2002) Characterization of a common precursor population for dendritic cells. Nature 425:1043","journal-title":"Nature"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1084\/jem.193.2.233","volume":"193","author":"Dhodapkar","year":"2001","unstructured":"Dhodapkar MV, Steinman RM, Krasovsky J, Munz C, Bhardwaj N (2001) Antigen-specific Inhibition of Effector T Cell Function in Humans after Injection of Immature Dendritic Cells. J Exp Med 193:233","journal-title":"J Exp Med"},{"key":"CR7","unstructured":"Donovan J, Brown P (1995) Euthanasia. In: Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W (eds) Current protocols in immunology, vol 1. Wiley, New York"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0304-3835(00)00618-2","volume":"161","author":"Felzmann","year":"2000","unstructured":"Felzmann T, Buchberger M, Jechlinger M, Kircheis R, Wagner E, Gadner H (2000) Xenogenization by tetanus toxoid loading into lymphoblastoid cell lines and primary human tumor cells mediated by polycations and liposomes. Cancer Lett 161:241","journal-title":"Cancer Lett"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1093\/intimm\/12.12.1741","volume":"12","author":"Ferlazzo","year":"2000","unstructured":"Ferlazzo G, Semino C, Spaggiari GM, Meta M, Mingari MC, Melioli G (2000) Dendritic cells efficiently cross-prime HLA class I-restricted cytolytic T lymphocytes when pulsed with both apoptotic and necrotic cells but not with soluble cell-derived lysates. Int Immunol 12:1741","journal-title":"Int Immunol"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1038\/15200","volume":"5","author":"Gallucci","year":"1999","unstructured":"Gallucci S, Lolkema M, Matzinger P (1999) Natural adjuvants: endogenous activators of dendritic cells. Nat Med 5:1249","journal-title":"Nat Med"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1007\/s00262-002-0359-2","volume":"52","author":"Graner","year":"2003","unstructured":"Graner MW, Zeng Y, Feng H, Katsanis E (2003) Tumor-derived chaperone-rich cell lysates are effective therapeutic vaccines against a variety of cancers. Cancer Immunol Immunother 52:226","journal-title":"Cancer Immunol Immunother"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1182\/blood.V95.3.879.003k13_879_885","volume":"95","author":"Guerriero","year":"2000","unstructured":"Guerriero A, Langmuir PB, Spain LM, Scott EW (2000) PU.1 is required for myeloid-derived but not lymphoid-derived dendritic cells. Blood 95:879","journal-title":"Blood"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1006\/smim.2001.0325","volume":"13","author":"Gunzer","year":"2001","unstructured":"Gunzer M, Janich S, Varga G, Grabbe S (2001) Dendritic cells and tumor immunity. Semin Immunol 13:291","journal-title":"Semin Immunol"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"3245","DOI":"10.1182\/blood.V90.9.3245","volume":"90","author":"Hart","year":"1997","unstructured":"Hart DN (1997) Dendritic cells: unique leukocyte populations which control the primary immune response. Blood 90:3245","journal-title":"Blood"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1182\/blood.V90.5.1920","volume":"90","author":"Hilkens","year":"1997","unstructured":"Hilkens CM, Kalinski P, deBoer M, Kapsenberg ML (1997) Human dendritic cells require exogenous interleukin-12-inducing factors to direct the development of naive T-helper cells toward the Th1 phenotype. Blood 90:1920","journal-title":"Blood"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1084\/jem.192.6.823","volume":"192","author":"Hochrein","year":"2000","unstructured":"Hochrein H, O?Keeffe M, Luft T, Vandenabeele S, Grumont RJ, Maraskovsky E, Shortman K (2000) Interleukin (IL)-4 is a major regulatory cytokine governing bioactive IL-12 production by mouse and human dendritic cells. J Exp Med 192:823","journal-title":"J Exp Med"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"3116","DOI":"10.1038\/79758","volume":"1","author":"Langenkamp","year":"2000","unstructured":"Langenkamp A, Messi M, Lanzavecchia A, Sallusto F (2000) Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells. Nat Immunol 1:3116","journal-title":"Nat Immunol"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0092-8674(01)00455-X","volume":"106","author":"Lanzavecchia","year":"2001","unstructured":"Lanzavecchia A, Sallusto F (2001) Regulation of T cell immunity by dendritic cells. Cell 106:263","journal-title":"Cell"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"3678","DOI":"10.4049\/jimmunol.166.6.3678","volume":"166","author":"Ludewig","year":"2001","unstructured":"Ludewig B, McCoy K, Pericin M, Ochsenbein AF, Dumrese T, Odermatt B, Toes REM, Melief CJM, Hengartner H, Zinkernagel RM (2001) Rapid peptide turnover and inefficient presentation of exogenous antigen critically limit the activation of self-reactive CTL by dendritic cells. J Immunol 166:3678","journal-title":"J Immunol"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"5071","DOI":"10.4049\/jimmunol.154.10.5071","volume":"154","author":"Macatonia","year":"1995","unstructured":"Macatonia SE, Hosken NA, Litton M, Vieira P, Hsieh CS, Culpepper JA, Wysocka M, Trinchieri G, Murphy KM, O?Garra A (1995) Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells. J Immunol 154:5071","journal-title":"J Immunol"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"3333","DOI":"10.1182\/blood.V97.11.3333","volume":"97","author":"Manz","year":"2001","unstructured":"Manz MG, Traver D, Miyamoto T, Weissman IL, Akashi K (2001) Dendritic cell potentials of early lymphoid and myeloid progenitors. Blood 97:3333","journal-title":"Blood"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"2511","DOI":"10.1182\/blood.V96.7.2511","volume":"96","author":"Martin","year":"2000","unstructured":"Martin P, del Hoyo GM, Anjuere F, Ruiz SR, Arias CF, Marin AR, Ardavin C (2000) Concept of lymphoid versus myeloid dendritic cell lineages revisited: both CD8alpha(-) and CD8alpha(+) dendritic cells are generated from CD4(low) lymphoid-committed precursors. Blood 96:2511","journal-title":"Blood"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"11786","DOI":"10.1073\/pnas.93.21.11786","volume":"93","author":"Mazzaccaro","year":"1996","unstructured":"Mazzaccaro RJ, Gedde M, Jensen ER, van Santen HM, Ploegh HL, Rock KL, Bloom BR (1996) Major histocompatibility class I presentation of soluble antigen facilitated by Mycobacterium tuberculosis infection. Proc Natl Acad Sci USA 93:11786","journal-title":"Proc Natl Acad Sci U S A"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/79734","volume":"1","author":"Moser","year":"2000","unstructured":"Moser M, Murphy KM (2000) Dendritic cell regulation of TH1-TH2 development. Nat Immunol 1:199","journal-title":"Nat Immunol"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1182\/blood-2002-10-3186","volume":"102","author":"Naik","year":"2003","unstructured":"Naik S, Vremec D, Wu L, O?Keeffe M, Shortman K (2003) CD8alpha+ mouse spleen dendritic cells do not originate from the CD8alpha-dendritic cell subset. Blood 102:601","journal-title":"Blood"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"6169","DOI":"10.1093\/nar\/18.20.6169","volume":"18","author":"Nishimura","year":"1990","unstructured":"Nishimura A, Morita M, Nishimura Y, Sugino Y (1990) A rapid and highly efficient method for preparation of competent Escherichia coli cells. Nucleic Acids Res 18:6169","journal-title":"Nucleic Acids Res"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1038\/30989","volume":"393","author":"Ridge","year":"1998","unstructured":"Ridge JP, Di-Rosa F, Matzinger P (1998) A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell. Nature 393:474","journal-title":"Nature"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1084\/jem.179.4.1109","volume":"179","author":"Sallusto","year":"1994","unstructured":"Sallusto F, Lanzavecchia A (1994) Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte\/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp Med 179:1109","journal-title":"J Exp Med"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1038\/31002","volume":"393","author":"Schoenberger","year":"1998","unstructured":"Schoenberger SP, Toes RE, van-der-Voort EI, Offringa R, Melief CJ (1998) T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature 393:480","journal-title":"Nature"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"6502","DOI":"10.4049\/jimmunol.163.12.6502","volume":"163","author":"Simmons","year":"1999","unstructured":"Simmons CP, Mastroeni P, Fowler R, Ghaem-maghami M, Lycke N, Pizza M, Rappuoli R, Dougan G (1999) MHC class I-restricted cytotoxic lymphocyte responses induced by enterotoxin-based mucosal adjuvants. J Immunol 163:6502","journal-title":"J Immunol"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1093\/intimm\/10.11.1593","volume":"10","author":"Snijders","year":"1998","unstructured":"Snijders A, Kalinski P, Hilkens CM, Kapsenberg ML (1998) High-level IL-12 production by human dendritic cells requires two signals. Int Immunol 10:1593","journal-title":"Int Immunol"},{"key":"CR32","first-page":"7563","volume":"61","author":"Tatsumi","year":"2001","unstructured":"Tatsumi T, Takehara T, Kanto T, Miyagi T, Kuzushita N, Sugimoto Y, Jinushi M, Kasahara A, Sasaki Y, Hori M, Hayashi N (2001) Administration of interleukin-12 enhances the therapeutic efficacy of dendritic cell-based tumor vaccines in mouse hepatocellular carcinoma. Cancer Res 61:7563","journal-title":"Cancer Res"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1084\/jem.189.5.753","volume":"189","author":"Toes","year":"1999","unstructured":"Toes RE, Ossendorp F, Offringa R, Melief CJ (1999) CD4 T cells and their role in antitumor immune responses. J Exp Med 189:753","journal-title":"J Exp Med"},{"key":"CR34","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/nri1001","volume":"3","author":"Trinchieri","year":"2003","unstructured":"Trinchieri G (2003) Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol 3:133","journal-title":"Nat Rev Immunol"},{"key":"CR35","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s00262-002-0338-7","volume":"52","author":"Vegh","year":"2003","unstructured":"Vegh Z, Mazumder A (2003) Generation of tumor cell lysate-loaded dendritic cells preprogrammed for IL-12 production and augmented T cell response. Cancer Immunol Immunother 52:67","journal-title":"Cancer Immunol Immunother"},{"key":"CR36","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/0008-8749(92)90291-V","volume":"142","author":"Wang","year":"1992","unstructured":"Wang P, Vanky F, Vegh Z, Persson U, Hising C, Klein E (1992) Assembly of MHC class I molecules in ex vivo carcinoma cells induced by IFN-gamma or by a binding peptide. Cell Immunol 142:296","journal-title":"Cell Immunol"},{"key":"CR37","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1007\/s00262-003-0468-6","volume":"53","author":"Whiteside","year":"2004","unstructured":"Whiteside T, Odoux C (2004) Dendritic cell biology and cancer therapy. Cancer Immunol Immunother 53:240","journal-title":"Cancer Immunol Immunother"}],"container-title":["Cancer Immunology, Immunotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00262-004-0571-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00262-004-0571-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00262-004-0571-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,29]],"date-time":"2023-04-29T05:59:31Z","timestamp":1682747971000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00262-004-0571-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,8,18]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["571"],"URL":"https:\/\/doi.org\/10.1007\/s00262-004-0571-3","relation":{},"ISSN":["0340-7004","1432-0851"],"issn-type":[{"value":"0340-7004","type":"print"},{"value":"1432-0851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,8,18]]}}}