{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T01:07:47Z","timestamp":1791248867403,"version":"4.1.0"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2007,2,6]],"date-time":"2007-02-06T00:00:00Z","timestamp":1170720000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2007,2,6]],"date-time":"2007-02-06T00:00:00Z","timestamp":1170720000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cancer Immunol Immunother"],"published-print":{"date-parts":[[2007,9]]},"DOI":"10.1007\/s00262-007-0286-3","type":"journal-article","created":{"date-parts":[[2007,2,5]],"date-time":"2007-02-05T09:38:52Z","timestamp":1170668332000},"page":"1459-1469","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":278,"title":["Density of DC-LAMP+ mature dendritic cells in combination with activated T lymphocytes infiltrating primary cutaneous melanoma is a strong independent prognostic factor"],"prefix":"10.1007","volume":"56","author":[{"given":"Andrea","family":"Lad\u00e1nyi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judit","family":"Kiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Be\u00e1ta","family":"Somlai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katalin","family":"Gilde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsuzsanna","family":"Fej\u0151s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Mohos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Istv\u00e1n","family":"Gaudi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f3zsef","family":"T\u00edm\u00e1r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2007,2,6]]},"reference":[{"key":"286_CR1","doi-asserted-by":"publisher","first-page":"1010","DOI":"10.1038\/ni722","volume":"2","author":"ML Albert","year":"2001","unstructured":"Albert ML, Jegathesan M, Darnell RB (2001) Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells. Nat Immunol 2:1010\u20131017","journal-title":"Nat Immunol"},{"key":"286_CR2","first-page":"1755","volume":"6","author":"B Almand","year":"2000","unstructured":"Almand B, Resser JR, Lindman B, Nadaf S, Clark JI, Kwon ED, Carbone DP, Gabrilovich DI (2000) Clinical significance of defective dendritic cell differentiation in cancer. Clin Cancer Res 6:1755\u20131766","journal-title":"Clin Cancer Res"},{"key":"286_CR3","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1002\/1097-0142(19890201)63:3<496::AID-CNCR2820630318>3.0.CO;2-K","volume":"63","author":"K Ambe","year":"1989","unstructured":"Ambe K, Mori M, Enjoji M (1989) S-100 protein-positive dendritic cells in colorectal adenocarcinomas. Distribution and relation to the clinical prognosis. Cancer 63:496\u2013503","journal-title":"Cancer"},{"key":"286_CR4","doi-asserted-by":"crossref","first-page":"3635","DOI":"10.1200\/JCO.2001.19.16.3635","volume":"19","author":"CM Balch","year":"2001","unstructured":"Balch CM, Buzaid AC, Soong S-J, Atkins MB, Cascinelli N, Coit DG, Fleming ID, Gershenwald JE, Houghton A Jr, Kirkwood JM, McMasters KM, Mihm MF, Morton DL, Reintgen DS, Ross MI, Sober A, Thompson JA, Thompson JF (2001) Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma. J Clin Oncol 19:3635\u20133648","journal-title":"J Clin Oncol"},{"key":"286_CR5","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1038\/32588","volume":"392","author":"J Banchereau","year":"1998","unstructured":"Banchereau J, Steinman RM (1998) Dendritic cells and the control of immunity. Nature 392:245\u2013252","journal-title":"Nature"},{"key":"286_CR6","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1084\/jem.190.10.1417","volume":"190","author":"D Bell","year":"1999","unstructured":"Bell D, Chomarat P, Broyles D, Netto G, Harb GM, Lebecque S, Valladeau J, Davoust J, Palucka KA, Banchereau J (1999) In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas. J Exp Med 190:1417\u20131425","journal-title":"J Exp Med"},{"key":"286_CR7","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1002\/ijc.2910410415","volume":"41","author":"EB Br\u00f6cker","year":"1988","unstructured":"Br\u00f6cker EB, Zwadlo G, Holzmann B, Macher E, Sorg C (1988) Inflammatory cell infiltrates in human melanoma at different stages of tumor progression. Int J Cancer 41:562\u2013567","journal-title":"Int J Cancer"},{"key":"286_CR8","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/S0952-7915(97)80153-7","volume":"9","author":"M Cella","year":"1997","unstructured":"Cella M, Sallusto F, Lanzavecchia A (1997) Origin, maturation and antigen presenting function of dendritic cells. Curr Opin Immunol 9:10\u201316","journal-title":"Curr Opin Immunol"},{"key":"286_CR9","first-page":"975","volume":"74","author":"P Chaux","year":"1996","unstructured":"Chaux P, Moutet M, Faivre J, Martin F, Martin M (1996) Inflammatory cells infiltrating human colorectal carcinomas express HLA class II but not B7-1 and B7-2 costimulatory molecules of the T-cell activation. Lab Invest 74:975\u2013983","journal-title":"Lab Invest"},{"key":"286_CR10","first-page":"225","volume":"18","author":"CT Conrad","year":"1999","unstructured":"Conrad CT, Ernst NR, Dummer W, Br\u00f6cker EB, Becker JC (1999) Differential expression of transforming growth factor beta 1 and interleukin 10 in progressing and regressing areas of primary melanoma. J Exp Clin Cancer Res 18:225\u2013232","journal-title":"J Exp Clin Cancer Res"},{"key":"286_CR11","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/S1074-7613(00)80615-9","volume":"9","author":"B de Saint-Vis","year":"1998","unstructured":"de Saint-Vis B, Vincent J, Vandenabeele S, Vanbervliet B, Pin JJ, Ait-Yahia S, Patel S, Mattei MG, Banchereau J, Zurawski S, Davoust J, Caux C, Lebecque S (1998) A novel lysosome-associated membrane glycoprotein, DC-LAMP, induced upon DC maturation, is transiently expressed in MHC class II compartment. Immunity 9:325\u2013336","journal-title":"Immunity"},{"key":"286_CR12","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1002\/(SICI)1097-0215(19971104)73:3<309::AID-IJC1>3.0.CO;2-3","volume":"73","author":"AH Enk","year":"1997","unstructured":"Enk AH, Jonuleit H, Saloga J, Knop J (1997) Dendritic cells as mediators of tumor-induced tolerance in metastatic melanoma. Int J Cancer 73:309\u2013316","journal-title":"Int J Cancer"},{"key":"286_CR13","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1002\/jlb.66.2.336","volume":"66","author":"C Esche","year":"1999","unstructured":"Esche C, Lokshin A, Shurin GV, Gastman BR, Rabinowich H, Watkins SC, Lotze MT, Shurin MR (1999) Tumor\u2019s other immune targets: dendritic cells. J Leukoc Biol 66:336\u2013344","journal-title":"J Leukoc Biol"},{"key":"286_CR14","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1007\/s00428-003-0918-8","volume":"443","author":"F Facchetti","year":"2003","unstructured":"Facchetti F, Vermi W, Mason D, Colonna M (2003) The plasmacytoid monocyte\/interferon producing cells. Virchows Arch 443:703\u2013717","journal-title":"Virchows Arch"},{"key":"286_CR15","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1111\/j.1600-0560.1998.tb01740.x","volume":"25","author":"DR Fullen","year":"1998","unstructured":"Fullen DR, Headington JT (1998) Factor XIIIa-positive dermal dendritic cells and HLA-DR expression in radial versus vertical growth-phase melanomas. J Cutan Pathol 25:553\u2013558","journal-title":"J Cutan Pathol"},{"key":"286_CR16","doi-asserted-by":"publisher","first-page":"1096","DOI":"10.1038\/nm1096-1096","volume":"2","author":"DI Gabrilovich","year":"1996","unstructured":"Gabrilovich DI, Chen HL, Girgis KR, Cunningham T, Meny GM, Nadaf S, Kavanaugh D, Carbone DP (1996) Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat Med 2:1096\u20131103","journal-title":"Nat Med"},{"key":"286_CR17","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1006\/cimm.1996.0139","volume":"170","author":"DI Gabrilovich","year":"1996","unstructured":"Gabrilovich DI, Ciernik F, Carbone DP (1996) Dendritic cells in antitumor immune responses I. Defective antigen presentation in tumor-bearing hosts. Cell Immunol 170:101\u2013110","journal-title":"Cell Immunol"},{"key":"286_CR18","first-page":"483","volume":"3","author":"DI Gabrilovich","year":"1997","unstructured":"Gabrilovich DI, Corak J, Ciernik IF, Kavanaugh D, Carbone DP (1997) Decreased antigen presentation by dendritic cells in patients with breast cancer. Clin Cancer Res 3:483\u2013490","journal-title":"Clin Cancer Res"},{"key":"286_CR19","doi-asserted-by":"crossref","first-page":"4567","DOI":"10.4049\/jimmunol.162.8.4567","volume":"162","author":"F Geissmann","year":"1999","unstructured":"Geissmann F, Revy P, Regnault A, Lepelletier Y, Dy M, Brousse N, Amigorena S, Hermine O, Durandy A (1999) TGF-\u03b21 prevents the noncognate maturation of human dendritic Langerhans cells. J Immunol 162:4567\u20134575","journal-title":"J Immunol"},{"key":"286_CR20","first-page":"3480","volume":"8","author":"N Inoshima","year":"2002","unstructured":"Inoshima N, Nakanishi Y, Minami T, Izumi M, Takayama K, Yoshino I, Hara N (2002) The influence of dendritic cell infiltration and vascular endothelial growth factor expression on the prognosis of non-small cell lung cancer. Clin Cancer Res 8:3480\u20133486","journal-title":"Clin Cancer Res"},{"key":"286_CR21","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1159\/000011837","volume":"55","author":"S Ishigami","year":"1998","unstructured":"Ishigami S, Aikou T, Natsugoe S, Hokita S, Iwashige H, Tokushige M, Sonoda S (1998) Prognostic value of HLA-DR expression and dendritic cell infiltration in gastric cancer. Oncology 55:65\u201369","journal-title":"Oncology"},{"key":"286_CR22","first-page":"1237","volume":"10","author":"S Ishigami","year":"2003","unstructured":"Ishigami S, Natsugoe S, Matsumoto M, Okumura H, Sakita H, Nakashima S, Takao S, Aikou T (2003) Clinical implications of intratumoral dendritic cell infiltration in esophageal squamous cell carcinoma. Oncol Rep 10:1237\u20131240","journal-title":"Oncol Rep"},{"key":"286_CR23","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1002\/ijc.10915","volume":"104","author":"M Iwamoto","year":"2003","unstructured":"Iwamoto M, Shinohara H, Miyamoto A, Okuzawa M, Mabuchi H, Nohara T, Gon G, Toyoda M, Tanigawa N (2003) Prognostic value of tumor-infiltrating dendritic cells expressing CD83 in human breast carcinomas. Int J Cancer 104:92\u201397","journal-title":"Int J Cancer"},{"key":"286_CR24","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1158\/1078-0432.CCR-1161-03","volume":"10","author":"A Lad\u00e1nyi","year":"2004","unstructured":"Lad\u00e1nyi A, Somlai B, Gilde K, Fej\u00f6s Z, Gaudi I, T\u00edm\u00e1r J (2004) T-cell activation marker expression on tumor-infiltrating lymphocytes as prognostic factor in cutaneous malignant melanoma. Clin Cancer Res 10:521\u2013530","journal-title":"Clin Cancer Res"},{"key":"286_CR25","doi-asserted-by":"crossref","first-page":"2587","DOI":"10.1172\/JCI116873","volume":"92","author":"A Lenz","year":"1993","unstructured":"Lenz A, Heine M, Schuler G, Romani N (1993) Human and murine dermis contain dendritic cells. J Clin Invest 92:2587\u20132596","journal-title":"J Clin Invest"},{"key":"286_CR26","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/S1471-4906(02)02281-0","volume":"23","author":"M Lutz","year":"2002","unstructured":"Lutz M, Schuler G (2002) Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol 23:445\u2013449","journal-title":"Trends Immunol"},{"key":"286_CR27","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1046\/j.1440-1711.2002.01115.x","volume":"80","author":"K Mahnke","year":"2002","unstructured":"Mahnke K, Schmitt E, Bonifaz L, Enk AH, Jonuleit H (2002) Immature but not inactive: the tolerogenic function of immature dendritic cells. Immunol Cell Biol 80:477\u2013483","journal-title":"Immunol Cell Biol"},{"key":"286_CR28","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1046\/j.1523-1747.1998.00375.x","volume":"111","author":"AD McLellan","year":"1998","unstructured":"McLellan AD, Heiser A, Sorg RV, Fearnley DB, Hart DNJ (1998) Dermal dendritic cells associated with T lymphocytes in normal human skin display an activated phenotype. J Invest Dermatol 111:841\u2013849","journal-title":"J Invest Dermatol"},{"key":"286_CR29","doi-asserted-by":"publisher","first-page":"2192","DOI":"10.1158\/0008-5472.CAN-03-2969","volume":"64","author":"M Movassagh","year":"2004","unstructured":"Movassagh M, Spatz A, Davoust J, Lebecque S, Romero P, Pittet M, Rimoldi D, Li\u00e9nard D, Gugerli O, Ferradini L, Robert C, Avril M-F, Zitvogel L, Angevin E (2004) Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma. Cancer Res 64:2192\u20132198","journal-title":"Cancer Res"},{"key":"286_CR30","doi-asserted-by":"crossref","first-page":"3488","DOI":"10.4049\/jimmunol.170.7.3488","volume":"170","author":"J P\u00e9guet-Navarro","year":"2003","unstructured":"P\u00e9guet-Navarro J, Sportouch M, Popa I, Berthier O, Schmitt D, Portoukalian J (2003) Gangliosides from human melanoma tumors impair dendritic cell differentiation from monocytes and induce their apoptosis. J Immunol 170:3488\u20133494","journal-title":"J Immunol"},{"key":"286_CR31","doi-asserted-by":"publisher","first-page":"2136","DOI":"10.1002\/1097-0142(20010601)91:11<2136::AID-CNCR1242>3.0.CO;2-Q","volume":"91","author":"TE Reichert","year":"2001","unstructured":"Reichert TE, Scheuer C, Day R, Wagner W, Whiteside TL (2001) The number of intratumoral dendritic cells and \u03b6-chain expression in T cells as prognostic and survival biomarkers in patients with oral carcinoma. Cancer 91:2136\u20132147","journal-title":"Cancer"},{"key":"286_CR32","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/S0002-9440(10)64951-6","volume":"156","author":"S Scarpino","year":"2000","unstructured":"Scarpino S, Stoppacciaro A, Ballerini F, Marchesi M, Prat M, Stella C, Sozzani S, Allavena P, Mantovani A, Ruco LP (2000) Papillary carcinoma of the thyroid: Hepatocyte growth factor (HGF) stimulates tumor cells to release chemokines active in recruiting dendritic cells. Am J Pathol 156:831\u2013837","journal-title":"Am J Pathol"},{"key":"286_CR33","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1038\/nri746","volume":"21","author":"K Shortman","year":"2002","unstructured":"Shortman K, Liu Y-J (2002) Mouse and human dendritic cell subtypes. Nat Rev Immunol 21:151\u2013161","journal-title":"Nat Rev Immunol"},{"key":"286_CR34","doi-asserted-by":"publisher","first-page":"1835","DOI":"10.1126\/science.284.5421.1835","volume":"284","author":"FP Siegal","year":"1999","unstructured":"Siegal FP, Kadowaki N, Shodell M, Fitzgerald-Bocarsly PA, Shah K, Ho S, Antonenko S, Liu Y-J (1999) The nature of the principal type 1 interferon-producing cells in human blood. Science 284:1835\u20131837","journal-title":"Science"},{"key":"286_CR35","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1182\/blood.V93.5.1634","volume":"93","author":"K Steinbrink","year":"1999","unstructured":"Steinbrink K, Jonuleit H, M\u00fcller G, Schuler G, Knop J, Enk AH (1999) Interleukin-10-treated human dendritic cells induce a melanoma-antigen-specific anergy in CD8+ T cells resulting in a failure to lyse tumor cells. Blood 93:1634\u20131642","journal-title":"Blood"},{"key":"286_CR36","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1146\/annurev.immunol.21.120601.141040","volume":"21","author":"RM Steinman","year":"2003","unstructured":"Steinman RM, Hawiger D, Nussenzweig MC (2003) Tolerogenic dendritic cells. Annu Rev Immunol 21:685\u2013711","journal-title":"Annu Rev Immunol"},{"key":"286_CR37","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1111\/1523-1747.ep12464142","volume":"91","author":"MA Stene","year":"1988","unstructured":"Stene MA, Babajanians M, Bhuta S, Cochran AJ (1988) Quantitative alterations in cutaneous Langerhans cells during the evolution of malignant melanoma of the skin. J Invest Dermatol 91:125\u2013128","journal-title":"J Invest Dermatol"},{"key":"286_CR38","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1002\/path.1018","volume":"196","author":"A Suzuki","year":"2002","unstructured":"Suzuki A, Masuda A, Nagata H, Kameoka S, Kikawada Y, Yamakawa M, Kasajima T (2002) Mature dendritic cells make clusters with T cells in the invasive margin of colorectal carcinoma. J Pathol 196:37\u201343","journal-title":"J Pathol"},{"key":"286_CR39","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1172\/JCI116236","volume":"91","author":"A Tazi","year":"1993","unstructured":"Tazi A, Bouchonnet F, Grandsaigne M, Boumsell L, Hance AJ, Soler P (1993) Evidence that granulocyte macrophage-colony-stimulating factor regulates the distribution and differentiated state of dendritic cells\/Langerhans cells in human lung and lung cancers. J Clin Invest 91:566\u2013576","journal-title":"J Clin Invest"},{"key":"286_CR40","doi-asserted-by":"publisher","first-page":"269S","DOI":"10.1111\/1523-1747.ep12470135","volume":"100","author":"K Toriyama","year":"1993","unstructured":"Toriyama K, Wen D-R, Paul E, Cochran AJ (1993) Variations in the distribution, frequency, and phenotype of Langerhans cells during the evolution of malignant melanoma of the skin. J Invest Dermatol 100:269S\u2013273S","journal-title":"J Invest Dermatol"},{"key":"286_CR41","first-page":"585","volume":"4","author":"AJ Troy","year":"1998","unstructured":"Troy AJ, Summers KL, Davidson PJT, Atkinson CH, Hart DNJ (1998) Minimal recruitment and activation of dendritic cells within renal cell carcinoma. Clin Cancer Res 4:585\u2013593","journal-title":"Clin Cancer Res"},{"key":"286_CR42","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1111\/j.1087-0024.2004.00838.x","volume":"9","author":"MC Udey","year":"2004","unstructured":"Udey MC (2004) Skin dendritic cells in immunity and autoimmunity. J Invest Dermatol Symp Proc 9:15\u201317","journal-title":"J Invest Dermatol Symp Proc"},{"key":"286_CR43","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1046\/j.1440-1711.1999.00857.x","volume":"77","author":"S Vandenabeele","year":"1999","unstructured":"Vandenabeele S, Wu L (1999) Dendritic cell origins: puzzles and paradoxes. Immunol Cell Biol 77:411\u2013419","journal-title":"Immunol Cell Biol"},{"key":"286_CR44","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1002\/path.1344","volume":"200","author":"W Vermi","year":"2003","unstructured":"Vermi W, Bonecchi R, Facchetti F, Bianchi D, Sozzani S, Festa S, Berenzi A, Cella M, Colonna M (2003) Recruitment of immature plasmacytoid dendritic cells (plasmacytoid monocytes) and myeloid dendritic cells in primary cutaneous melanomas. J Pathol 200:255\u2013268","journal-title":"J Pathol"},{"key":"286_CR45","doi-asserted-by":"publisher","first-page":"8456","DOI":"10.1158\/0008-5472.CAN-03-3251","volume":"64","author":"RJCLM Vuylsteke","year":"2004","unstructured":"Vuylsteke RJCLM, Molenkamp BG, Gietema HA, van Leeuwen PAM, Wijnands PGJTB, Vos W, van Diest PJ, Scheper RJ, Meijer S, de Gruijl TD (2004) Local administration of granulocyte\/macrophage colony-stimulating factor increases the number and activation state of dendritic cells in the sentinel lymph node of early-stage melanoma. Cancer Res 64:8456\u20138460","journal-title":"Cancer Res"},{"key":"286_CR46","doi-asserted-by":"crossref","first-page":"3821","DOI":"10.4049\/jimmunol.154.8.3821","volume":"154","author":"LJ Zhou","year":"1995","unstructured":"Zhou LJ, Tedder TF (1995) Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily. J Immunol 154:3821\u20133835","journal-title":"J Immunol"}],"container-title":["Cancer Immunology, Immunotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00262-007-0286-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00262-007-0286-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00262-007-0286-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00262-007-0286-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,10]],"date-time":"2024-02-10T13:54:53Z","timestamp":1707573293000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00262-007-0286-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2,6]]},"references-count":46,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["286"],"URL":"https:\/\/doi.org\/10.1007\/s00262-007-0286-3","relation":{},"ISSN":["0340-7004","1432-0851"],"issn-type":[{"value":"0340-7004","type":"print"},{"value":"1432-0851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,2,6]]},"assertion":[{"value":"26 October 2006","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 December 2006","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 February 2007","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}