{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T05:14:22Z","timestamp":1769750062101,"version":"3.49.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer Immunol Immunother"],"published-print":{"date-parts":[[2009,3]]},"DOI":"10.1007\/s00262-008-0569-3","type":"journal-article","created":{"date-parts":[[2008,8,21]],"date-time":"2008-08-21T11:23:32Z","timestamp":1219317812000},"page":"429-439","source":"Crossref","is-referenced-by-count":16,"title":["Aberrant expression of the hematopoietic-restricted minor histocompatibility antigen LRH-1 on solid tumors results in efficient cytotoxic T cell-mediated lysis"],"prefix":"10.1007","volume":"58","author":[{"given":"Ingrid M.","family":"Overes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Henri\u00ebtte Levenga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna C. M.","family":"Vos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnes","family":"van Horssen-Zoetbrood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robbert","family":"van der Voort","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pieter H.","family":"De Mulder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theo M.","family":"de Witte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harry","family":"Dolstra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,8,22]]},"reference":[{"issue":"4","key":"569_CR1","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1152\/physiol.00002.2004","volume":"19","author":"R Abele","year":"2004","unstructured":"Abele R, Tampe R (2004) The ABCs of immunology: structure and function of TAP, the transporter associated with antigen processing. Physiology 19(4):216\u2013224","journal-title":"Physiology"},{"issue":"8","key":"569_CR2","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1111\/j.1349-7006.2007.00521.x","volume":"98","author":"Y Akatsuka","year":"2007","unstructured":"Akatsuka Y, Morishima Y, Kuzushima K, Kodera Y, Takahashi T (2007) Minor histocompatibility antigens as targets for immunotherapy using allogeneic immune reactions. Cancer Sci 98(8):1139\u20131146","journal-title":"Cancer Sci"},{"issue":"6835","key":"569_CR3","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/35077251","volume":"411","author":"FR Appelbaum","year":"2001","unstructured":"Appelbaum FR (2001) Haematopoietic cell transplantation as immunotherapy. Nature 411(6835):385\u2013389","journal-title":"Nature"},{"issue":"1","key":"569_CR4","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1038\/ncponc0019","volume":"1","author":"M Arya","year":"2004","unstructured":"Arya M, Chao D, Patel HR (2004) Allogeneic hematopoietic stem-cell transplantation: the next generation of therapy for metastatic renal cell cancer. Nat Clin Pract Oncol 1(1):32\u201338","journal-title":"Nat Clin Pract Oncol"},{"issue":"11","key":"569_CR5","doi-asserted-by":"crossref","first-page":"4234","DOI":"10.1182\/blood.V99.11.4234","volume":"99","author":"M Bregni","year":"2002","unstructured":"Bregni M, Dodero A, Peccatori J, Pescarollo A, Bernardi M, Sassi I, Voena C, Zaniboni A, Bordignon C, Corradini P (2002) Nonmyeloablative conditioning followed by hematopoietic cell allografting and donor lymphocyte infusions for patients with metastatic renal and breast cancer. Blood 99(11):4234\u20134236","journal-title":"Blood"},{"issue":"11","key":"569_CR6","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1056\/NEJM200009143431101","volume":"343","author":"R Childs","year":"2000","unstructured":"Childs R, Chernoff A, Contentin N, Bahceci E, Schrump D, Leitman S, Read EJ, Tisdale J, Dunbar C, Linehan WM, Young NS, Barrett AJ (2000) Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation. N Engl J Med 343(11):750\u2013758","journal-title":"N Engl J Med"},{"issue":"12","key":"569_CR7","doi-asserted-by":"crossref","first-page":"3506","DOI":"10.1172\/JCI24832","volume":"115","author":"B Rijke de","year":"2005","unstructured":"de Rijke B, Horssen-Zoetbrood A, Beekman JM, Otterud B, Maas F, Woestenenk R, Kester M, Leppert M, Schattenberg AV, de Witte T, van de Wiel-van Kemenade E, Dolstra H (2005) A frameshift polymorphism in P2X5 elicits an allogeneic cytotoxic T lymphocyte response associated with remission of chronic myeloid leukemia. J Clin Invest 115(12):3506\u20133516","journal-title":"J Clin Invest"},{"issue":"8","key":"569_CR8","doi-asserted-by":"crossref","first-page":"2591","DOI":"10.1182\/blood-2004-02-0459","volume":"104","author":"A Dorrschuck","year":"2004","unstructured":"Dorrschuck A, Schmidt A, Schnurer E, Gluckmann M, Albrecht C, Wolfel C, Lennerz V, Lifke A, Di Natale C, Ranieri E, Gesualdo L, Huber C, Karas M, Wolfel T, Herr W (2004) CD8+ cytotoxic T lymphocytes isolated from allogeneic healthy donors recognize HLA class Ia\/Ib-associated renal carcinoma antigens with ubiquitous or restricted tissue expression. Blood 104(8):2591\u20132599","journal-title":"Blood"},{"issue":"11","key":"569_CR9","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1038\/nri1961","volume":"6","author":"GP Dunn","year":"2006","unstructured":"Dunn GP, Koebel CM, Schreiber RD (2006) Interferons, immunity and cancer immunoediting. Nat Rev Immunol 6(11):836\u2013848","journal-title":"Nat Rev Immunol"},{"issue":"4","key":"569_CR10","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1182\/blood.V88.4.1501.bloodjournal8841501","volume":"88","author":"B Eibl","year":"1996","unstructured":"Eibl B, Schwaighofer H, Nachbaur D, Marth C, Gachter A, Knapp R, Bock G, Gassner C, Schiller L, Petersen F, Niederwieser D (1996) Evidence for a graft-versus-tumor effect in a patient treated with marrow ablative chemotherapy and allogeneic bone marrow transplantation for breast cancer. Blood 88(4):1501\u20131508","journal-title":"Blood"},{"issue":"11","key":"569_CR11","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1200\/JCO.2005.03.9115","volume":"24","author":"JA Foekens","year":"2006","unstructured":"Foekens JA, Atkins D, Zhang Y, Sweep FC, Harbeck N, Paradiso A, Cufer T, Sieuwerts AM, Talantov D, Span PN, Tjan-Heijnen VC, Zito AF, Specht K, Hoefler H, Golouh R, Schittulli F, Schmitt M, Beex LV, Klijn JG, Wang Y (2006) Multicenter validation of a gene expression-based prognostic signature in lymph node-negative primary breast cancer. J Clin Oncol 24(11):1665\u20131671","journal-title":"J Clin Oncol"},{"issue":"7","key":"569_CR12","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1097\/00007890-200204150-00022","volume":"73","author":"N Fujii","year":"2002","unstructured":"Fujii N, Hiraki A, Ikeda K, Ohmura Y, Nozaki I, Shinagawa K, Ishimaru F, Kiura K, Shimizu N, Tanimoto M, Harada M (2002) Expression of minor histocompatibility antigen, HA-1, in solid tumor cells. Transplantation 73(7):1137\u20131141","journal-title":"Transplantation"},{"issue":"3","key":"569_CR13","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1182\/blood.V75.3.555.555","volume":"75","author":"MM Horowitz","year":"1990","unstructured":"Horowitz MM, Gale RP, Sondel PM, Goldman JM, Kersey J, Kolb HJ, Rimm AA, Ringden O, Rozman C, Speck B (1990) Graft-versus-leukemia reactions after bone marrow transplantation. Blood 75(3):555\u2013562","journal-title":"Blood"},{"issue":"3","key":"569_CR14","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s11060-008-9577-6","volume":"88","author":"JF Jacobs","year":"2008","unstructured":"Jacobs JF, Grauer OM, Brasseur F, Hoogerbrugge PM, Wesseling P, Gidding CE, van de Rakt MW, Figdor CG, Coulie PG, de Vries IJ, Adema GJ (2008) Selective cancer-germline gene expression in pediatric brain tumors. J Neurooncol 88(3):273\u2013280","journal-title":"J Neurooncol"},{"issue":"7","key":"569_CR15","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.1182\/blood-2003-06-2070","volume":"103","author":"I Jedema","year":"2004","unstructured":"Jedema I, van der Werff NM, Barge RM, Willemze R, Falkenburg JH (2004) New CFSE-based assay to determine susceptibility to lysis by cytotoxic T cells of leukemic precursor cells within a heterogeneous target cell population. Blood 103(7):2677\u20132682","journal-title":"Blood"},{"issue":"3","key":"569_CR16","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1084\/jem.20011838","volume":"196","author":"CA Klein","year":"2002","unstructured":"Klein CA, Wilke M, Pool J, Vermeulen C, Blokland E, Burghart E, Krostina S, Wendler N, Passlick B, Riethmueller G, Goulmy E (2002) The hematopoietic system-specific minor histocompatibility antigen HA-1 shows aberrant expression in epithelial cancer cells. J Exp Med 196(3):359\u2013368","journal-title":"J Exp Med"},{"issue":"12","key":"569_CR17","doi-asserted-by":"crossref","first-page":"3955","DOI":"10.1182\/blood-2004-09-3749","volume":"106","author":"FM Kloosterboer","year":"2005","unstructured":"Kloosterboer FM, Luxemburg-Heijs SA, van Soest RA, van Egmond HM, Willemze R, Falkenburg JH (2005) Up-regulated expression in nonhematopoietic tissues of the BCL2A1-derived minor histocompatibility antigens in response to inflammatory cytokines: relevance for allogeneic immunotherapy of leukemia. Blood 106(12):3955\u20133957","journal-title":"Blood"},{"issue":"11","key":"569_CR18","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1038\/nm1311","volume":"11","author":"MC Meunier","year":"2005","unstructured":"Meunier MC, Delisle JS, Bergeron J, Rineau V, Baron C, Perreault C (2005) T cells targeted against a single minor histocompatibility antigen can cure solid tumors. Nat Med 11(11):1222\u20131229","journal-title":"Nat Med"},{"issue":"3","key":"569_CR19","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/S1521-6616(03)00065-2","volume":"107","author":"M Miyazaki","year":"2003","unstructured":"Miyazaki M, Akatsuka Y, Nishida T, Fujii N, Hiraki A, Ikeda K, Tsujimura K, Kuzushima K, Morishima Y, Sato S, Ueda R, Takahashi T (2003) Potential limitations in using minor histocompatibility antigen-specific cytotoxic T cells for targeting solid tumor cells. Clin Immunol 107(3):198\u2013201","journal-title":"Clin Immunol"},{"issue":"6","key":"569_CR20","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1111\/j.1365-2141.2008.07125.x","volume":"141","author":"IM Overes","year":"2008","unstructured":"Overes IM, de Rijke B, Horssen-Zoetbrood A, Fredrix H, de Graaf AO, Jansen JH, van Krieken JH, Raymakers RA, van der Voort R, de Witte TM, Dolstra H (2008) Expression of P2X5 in lymphoid malignancies results in LRH-1-specific cytotoxic T-cell-mediated lysis. Br J Haematol 141(6):799\u2013807","journal-title":"Br J Haematol"},{"issue":"9","key":"569_CR21","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1002\/cncr.10491","volume":"94","author":"P Pedrazzoli","year":"2002","unstructured":"Pedrazzoli P, Da Prada GA, Giorgiani G, Schiavo R, Zambelli A, Giraldi E, Landonio G, Locatelli F, Siena S, Della Cuna GR (2002) Allogeneic blood stem cell transplantation after a reduced-intensity, preparative regimen: a pilot study in patients with refractory malignancies. Cancer 94(9):2409\u20132415","journal-title":"Cancer"},{"issue":"8","key":"569_CR22","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1200\/JCO.2002.08.068","volume":"20","author":"BI Rini","year":"2002","unstructured":"Rini BI, Zimmerman T, Stadler WM, Gajewski TF, Vogelzang NJ (2002) Allogeneic stem-cell transplantation of renal cell cancer after nonmyeloablative chemotherapy: feasibility, engraftment, and clinical results. J Clin Oncol 20(8):2017\u20132024","journal-title":"J Clin Oncol"},{"issue":"12","key":"569_CR23","doi-asserted-by":"crossref","first-page":"4954","DOI":"10.1182\/blood-2005-09-3883","volume":"107","author":"EH Slager","year":"2006","unstructured":"Slager EH, Honders MW, van der Meijden ED, Luxemburg-Heijs SA, Kloosterboer FM, Kester MG, Jedema I, Marijt WA, Schaafsma MR, Willemze R, Falkenburg JH (2006) Identification of the angiogenic endothelial-cell growth factor-1\/thymidine phosphorylase as a potential target for immunotherapy of cancer. Blood 107(12):4954\u20134960","journal-title":"Blood"},{"issue":"2","key":"569_CR24","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.it.2003.12.002","volume":"25","author":"E Spierings","year":"2004","unstructured":"Spierings E, Wieles B, Goulmy E (2004) Minor histocompatibility antigens\u2014big in tumour therapy. Trends Immunol 25(2):56\u201360","journal-title":"Trends Immunol"},{"issue":"3","key":"569_CR25","first-page":"1099","volume":"118","author":"Y Takahashi","year":"2008","unstructured":"Takahashi Y, Harashima N, Kajigaya S, Yokoyama H, Cherkasova E, McCoy JP, Hanada KI, Mena O, Kurlander R, Abdul T, Srinivasan R, Lundqvist A, Malinzak E, Geller N, Lerman MI, Childs RW (2008) Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells. J Clin Invest 118(3):1099\u20131109","journal-title":"J Clin Invest"},{"issue":"23","key":"569_CR26","doi-asserted-by":"crossref","first-page":"7799","DOI":"10.1158\/1078-0432.CCR-04-0072","volume":"10","author":"SS Tykodi","year":"2004","unstructured":"Tykodi SS, Warren EH, Thompson JA, Riddell SR, Childs RW, Otterud BE, Leppert MF, Storb R, Sandmaier BM (2004) Allogeneic hematopoietic cell transplantation for metastatic renal cell carcinoma after nonmyeloablative conditioning: toxicity, clinical response, and immunological response to minor histocompatibility antigens. Clin Cancer Res 10(23):7799\u20137811","journal-title":"Clin Cancer Res"},{"issue":"3","key":"569_CR27","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1200\/JCO.1998.16.3.986","volume":"16","author":"NT Ueno","year":"1998","unstructured":"Ueno NT, Rondon G, Mirza NQ, Geisler DK, Anderlini P, Giralt SA, Andersson BS, Claxton DF, Gajewski JL, Khouri IF, Korbling M, Mehra RC, Przepiorka D, Rahman Z, Samuels BI, van Besien K, Hortobagyi GN, Champlin RE (1998) Allogeneic peripheral-blood progenitor-cell transplantation for poor-risk patients with metastatic breast cancer. J Clin Oncol 16(3):986\u2013993","journal-title":"J Clin Oncol"}],"container-title":["Cancer Immunology, Immunotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00262-008-0569-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,7]],"date-time":"2020-05-07T21:12:51Z","timestamp":1588885971000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00262-008-0569-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8,22]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["569"],"URL":"https:\/\/doi.org\/10.1007\/s00262-008-0569-3","relation":{},"ISSN":["0340-7004","1432-0851"],"issn-type":[{"value":"0340-7004","type":"print"},{"value":"1432-0851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,8,22]]}}}