{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:45:50Z","timestamp":1790837150605,"version":"4.1.0"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2016,7,20]],"date-time":"2016-07-20T00:00:00Z","timestamp":1468972800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"University of California, Los Angeles - Faculty Grants Program"},{"DOI":"10.13039\/100007185","name":"University of California, Los Angeles (US) - School of Dentistry","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007185","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Polish Ministry of Science and Higher Education"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cancer Immunol Immunother"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1007\/s00262-016-1866-x","type":"journal-article","created":{"date-parts":[[2016,7,20]],"date-time":"2016-07-20T13:38:53Z","timestamp":1469021933000},"page":"1085-1097","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["Resistance to cytotoxicity and sustained release of interleukin-6 and interleukin-8 in the presence of decreased interferon-\u03b3 after differentiation of glioblastoma by human natural killer cells"],"prefix":"10.1007","volume":"65","author":[{"given":"Anna K.","family":"Kozlowska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han-Ching","family":"Tseng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kawaljit","family":"Kaur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paytsar","family":"Topchyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihito","family":"Inagaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vickie T.","family":"Bui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriyuki","family":"Kasahara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Cacalano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anahid","family":"Jewett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,7,20]]},"reference":[{"key":"1866_CR1","unstructured":"Safari M, Khoshnevisan A (2015) Cancer stem cells and chemoresistance in glioblastoma multiform: a review article. J Stem Cells 10(4):271\u2013285"},{"issue":"3","key":"1866_CR2","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1158\/1541-7786.MCR-08-0409","volume":"7","author":"M Ropolo","year":"2009","unstructured":"Ropolo M, Daga A, Griffero F, Foresta M, Casartelli G, Zunino A, Poggi A, Cappelli E, Zona G, Spaziante R, Corte G, Frosina G (2009) Comparative analysis of DNA repair in stem and nonstem glioma cell cultures. Mol Cancer Res 7(3):383\u2013392. doi: 10.1158\/1541-7786.MCR-08-0409","journal-title":"Mol Cancer Res"},{"issue":"6","key":"1866_CR3","first-page":"9114","volume":"8","author":"Y Shan","year":"2015","unstructured":"Shan Y, He X, Song W, Han D, Niu J, Wang J (2015) Role of IL-6 in the invasiveness and prognosis of glioma. Int J Clin Exp Med 8(6):9114\u20139120","journal-title":"Int J Clin Exp Med"},{"issue":"4","key":"1866_CR4","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S1359-6101(01)00016-8","volume":"12","author":"K Xie","year":"2001","unstructured":"Xie K (2001) Interleukin-8 and human cancer biology. Cytokine Growth Factor Rev 12(4):375\u2013391","journal-title":"Cytokine Growth Factor Rev"},{"issue":"1","key":"1866_CR5","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/BF02478920","volume":"18","author":"A Sasaki","year":"2001","unstructured":"Sasaki A, Ishiuchi S, Kanda T, Hasegawa M, Nakazato Y (2001) Analysis of interleukin-6 gene expression in primary human gliomas, glioblastoma xenografts, and glioblastoma cell lines. Brain Tumor Pathol 18(1):13\u201321","journal-title":"Brain Tumor Pathol"},{"issue":"7","key":"1866_CR6","doi-asserted-by":"publisher","first-page":"1447","DOI":"10.1038\/sj.onc.1202424","volume":"18","author":"I Desbaillets","year":"1999","unstructured":"Desbaillets I, Diserens AC, de Tribolet N, Hamou MF, Van Meir EG (1999) Regulation of interleukin-8 expression by reduced oxygen pressure in human glioblastoma. Oncogene 18(7):1447\u20131456. doi: 10.1038\/sj.onc.1202424","journal-title":"Oncogene"},{"issue":"8","key":"1866_CR7","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1084\/jem.186.8.1201","volume":"186","author":"I Desbaillets","year":"1997","unstructured":"Desbaillets I, Diserens AC, Tribolet N, Hamou MF, Van Meir EG (1997) Upregulation of interleukin 8 by oxygen-deprived cells in glioblastoma suggests a role in leukocyte activation, chemotaxis, and angiogenesis. J Exp Med 186(8):1201\u20131212","journal-title":"J Exp Med"},{"issue":"1","key":"1866_CR8","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/BF01324831","volume":"16","author":"M Tada","year":"1993","unstructured":"Tada M, Suzuki K, Yamakawa Y, Sawamura Y, Sakuma S, Abe H, van Meir E, de Tribolet N (1993) Human glioblastoma cells produce 77 amino acid interleukin-8 (IL-8(77)). J Neurooncol 16(1):25\u201334","journal-title":"J Neurooncol"},{"issue":"16","key":"1866_CR9","first-page":"4297","volume":"52","author":"E Meir Van","year":"1992","unstructured":"Van Meir E, Ceska M, Effenberger F, Walz A, Grouzmann E, Desbaillets I, Frei K, Fontana A, de Tribolet N (1992) Interleukin-8 is produced in neoplastic and infectious diseases of the human central nervous system. Cancer Res 52(16):4297\u20134305","journal-title":"Cancer Res"},{"key":"1866_CR10","doi-asserted-by":"publisher","first-page":"269","DOI":"10.3389\/fimmu.2014.00269","volume":"5","author":"HC Tseng","year":"2014","unstructured":"Tseng HC, Bui V, Man YG, Cacalano N, Jewett A (2014) Induction of split anergy conditions natural killer cells to promote differentiation of stem cells through cell\u2013cell contact and secreted factors. Front Immunol 5:269. doi: 10.3389\/fimmu.2014.00269","journal-title":"Front Immunol"},{"issue":"1","key":"1866_CR11","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1007\/s11060-013-1258-4","volume":"116","author":"T Nakazawa","year":"2014","unstructured":"Nakazawa T, Nakamura M, Park YS, Motoyama Y, Hironaka Y, Nishimura F, Nakagawa I, Yamada S, Matsuda R, Tamura K, Sugimoto T, Takeshima Y, Marutani A, Tsujimura T, Ouji N, Ouji Y, Yoshikawa M, Nakase H (2014) Cytotoxic human peripheral blood-derived gammadelta T cells kill glioblastoma cell lines: implications for cell-based immunotherapy for patients with glioblastoma. J Neurooncol 116(1):31\u201339. doi: 10.1007\/s11060-013-1258-4","journal-title":"J Neurooncol"},{"issue":"6","key":"1866_CR12","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1097\/CCO.0000000000000135","volume":"26","author":"G Finocchiaro","year":"2014","unstructured":"Finocchiaro G, Pellegatta S (2014) Perspectives for immunotherapy in glioblastoma treatment. Curr Opin Oncol 26(6):608\u2013614. doi: 10.1097\/CCO.0000000000000135","journal-title":"Curr Opin Oncol"},{"key":"1866_CR13","doi-asserted-by":"publisher","first-page":"63","DOI":"10.3389\/fimmu.2013.00063","volume":"4","author":"C Chanvillard","year":"2013","unstructured":"Chanvillard C, Jacolik RF, Infante-Duarte C, Nayak RC (2013) The role of natural killer cells in multiple sclerosis and their therapeutic implications. Front Immunol 4:63. doi: 10.3389\/fimmu.2013.00063","journal-title":"Front Immunol"},{"issue":"Pt 9","key":"1866_CR14","doi-asserted-by":"publisher","first-page":"2657","DOI":"10.1093\/brain\/aws159","volume":"136","author":"G Kaur","year":"2013","unstructured":"Kaur G, Trowsdale J, Fugger L (2013) Natural killer cells and their receptors in multiple sclerosis. Brain 136(Pt 9):2657\u20132676. doi: 10.1093\/brain\/aws159","journal-title":"Brain"},{"issue":"11","key":"1866_CR15","doi-asserted-by":"publisher","first-page":"5355","DOI":"10.4049\/jimmunol.1203401","volume":"190","author":"A Poli","year":"2013","unstructured":"Poli A, Kmiecik J, Domingues O, Hentges F, Blery M, Chekenya M, Boucraut J, Zimmer J (2013) NK cells in central nervous system disorders. J Immunol 190(11):5355\u20135362. doi: 10.4049\/jimmunol.1203401","journal-title":"J Immunol"},{"issue":"9","key":"1866_CR16","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.18632\/oncotarget.1291","volume":"4","author":"A Poli","year":"2013","unstructured":"Poli A, Wang J, Domingues O, Planaguma J, Yan T, Rygh CB, Skaftnesmo KO, Thorsen F, McCormack E, Hentges F, Pedersen PH, Zimmer J, Enger PO, Chekenya M (2013) Targeting glioblastoma with NK cells and mAb against NG2\/CSPG4 prolongs animal survival. Oncotarget 4(9):1527\u20131546","journal-title":"Oncotarget"},{"issue":"4","key":"1866_CR17","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1006\/cyto.1995.0047","volume":"7","author":"I Tsuboi","year":"1995","unstructured":"Tsuboi I, Tanaka H, Nakao M, Shichijo S, Itoh K (1995) Nonsteroidal anti-inflammatory drugs differentially regulate cytokine production in human lymphocytes: up-regulation of TNF, IFN-gamma and IL-2, in contrast to down-regulation of IL-6 production. Cytokine 7(4):372\u2013379","journal-title":"Cytokine"},{"issue":"24 Pt 1","key":"1866_CR18","first-page":"6992","volume":"48","author":"S Miescher","year":"1988","unstructured":"Miescher S, Stoeck M, Qiao L, Barras C, Barrelet L, von Fliedner V (1988) Preferential clonogenic deficit of CD8-positive T-lymphocytes infiltrating human solid tumors. Cancer Res 48(24 Pt 1):6992\u20136998","journal-title":"Cancer Res"},{"issue":"3","key":"1866_CR19","first-page":"167","volume":"77","author":"J Qin","year":"1997","unstructured":"Qin J, Han B, Pang J (1997) The relationship between TIL from human primary hepatic carcinoma and prognosis. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 77(3):167\u2013170 (Article in Chinese)","journal-title":"Zhonghua Yi Xue Yi Chuan Xue Za Zhi"},{"issue":"3","key":"1866_CR20","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1006\/gyno.1997.4668","volume":"65","author":"X Han","year":"1997","unstructured":"Han X, Papadopoulos AJ, Ruparelia V, Devaja O, Raju KS (1997) Tumor lymphocytes in patients with advanced ovarian cancer: changes during in vitro culture and implications for immunotherapy. Gynecol Oncol 65(3):391\u2013398","journal-title":"Gynecol Oncol"},{"issue":"5","key":"1866_CR21","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/j.ccr.2006.03.030","volume":"9","author":"J Lee","year":"2006","unstructured":"Lee J, Kotliarova S, Kotliarov Y, Li A, Su Q, Donin NM, Pastorino S, Purow BW, Christopher N, Zhang W, Park JK, Fine HA (2006) Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 9(5):391\u2013403. doi: 10.1016\/j.ccr.2006.03.030","journal-title":"Cancer Cell"},{"issue":"6","key":"1866_CR22","doi-asserted-by":"publisher","first-page":"3530","DOI":"10.4049\/jimmunol.0802845","volume":"182","author":"R Castriconi","year":"2009","unstructured":"Castriconi R, Daga A, Dondero A, Zona G, Poliani PL, Melotti A, Griffero F, Marubbi D, Spaziante R, Bellora F, Moretta L, Moretta A, Corte G, Bottino C (2009) NK cells recognize and kill human glioblastoma cells with stem cell-like properties. J Immunol 182(6):3530\u20133539. doi: 10.4049\/jimmunol.0802845","journal-title":"J Immunol"},{"issue":"1","key":"1866_CR23","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1007\/BF01540972","volume":"16","author":"A Jewett","year":"1996","unstructured":"Jewett A, Gan XH, Lebow LT, Bonavida B (1996) Differential secretion of TNF-alpha and IFN-gamma by human peripheral blood-derived NK subsets and association with functional maturation. J Clin Immunol 16(1):46\u201354","journal-title":"J Clin Immunol"},{"issue":"10","key":"1866_CR24","doi-asserted-by":"crossref","first-page":"4815","DOI":"10.4049\/jimmunol.159.10.4815","volume":"159","author":"A Jewett","year":"1997","unstructured":"Jewett A, Cavalcanti M, Bonavida B (1997) Pivotal role of endogenous TNF-alpha in the induction of functional inactivation and apoptosis in NK cells. J Immunol 159(10):4815\u20134822","journal-title":"J Immunol"},{"issue":"3","key":"1866_CR25","doi-asserted-by":"crossref","first-page":"907","DOI":"10.4049\/jimmunol.156.3.907","volume":"156","author":"A Jewett","year":"1996","unstructured":"Jewett A, Bonavida B (1996) Target-induced inactivation and cell death by apoptosis in a subset of human NK cells. J Immunol 156(3):907\u2013915","journal-title":"J Immunol"},{"issue":"1","key":"1866_CR26","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0008-8749(95)80013-9","volume":"160","author":"A Jewett","year":"1995","unstructured":"Jewett A, Bonavida B (1995) Target-induced anergy of natural killer cytotoxic function is restricted to the NK-target conjugate subset. Cell Immunol 160(1):91\u201397","journal-title":"Cell Immunol"},{"issue":"1","key":"1866_CR27","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1006\/clim.2000.4871","volume":"96","author":"A Jewett","year":"2000","unstructured":"Jewett A, Bonavida B (2000) MHC-Class I antigens regulate both the function and the survival of human peripheral blood NK cells: role of endogenously secreted TNF-alpha. Clin Immunol 96(1):19\u201328","journal-title":"Clin Immunol"},{"issue":"7 Pt 1","key":"1866_CR28","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1158\/1078-0432.CCR-05-2306","volume":"12","author":"A Jewett","year":"2006","unstructured":"Jewett A, Cacalano NA, Head C, Teruel A (2006) Coengagement of CD16 and CD94 receptors mediates secretion of chemokines and induces apoptotic death of naive natural killer cells. Clin Cancer Res 12(7 Pt 1):1994\u20132003","journal-title":"Clin Cancer Res"},{"issue":"7","key":"1866_CR29","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1007\/s00262-007-0437-6","volume":"57","author":"A Jewett","year":"2008","unstructured":"Jewett A, Teruel A, Romero M, Head C, Cacalano N (2008) Rapid and potent induction of cell death and loss of NK cell cytotoxicity against oral tumors by F(ab\u2019)2 fragment of anti-CD16 antibody. Cancer Immunol Immunother 57(7):1053\u20131066","journal-title":"Cancer Immunol Immunother"},{"issue":"1","key":"1866_CR30","first-page":"161","volume":"2","author":"P Lai","year":"1996","unstructured":"Lai P, Rabinowich H, Crowley-Nowick PA, Bell MC, Mantovani G, Whiteside TL (1996) Alterations in expression and function of signal-transducing proteins in tumor-associated T and natural killer cells in patients with ovarian carcinoma. Clin Cancer Res 2(1):161\u2013173","journal-title":"Clin Cancer Res"},{"issue":"2","key":"1866_CR31","first-page":"329","volume":"5","author":"I Kuss","year":"1999","unstructured":"Kuss I, Saito T, Johnson JT, Whiteside TL (1999) Clinical significance of decreased zeta chain expression in peripheral blood lymphocytes of patients with head and neck cancer. Clin Cancer Res 5(2):329\u2013334","journal-title":"Clin Cancer Res"},{"issue":"7","key":"1866_CR32","doi-asserted-by":"publisher","first-page":"e11590","DOI":"10.1371\/journal.pone.0011590","volume":"5","author":"HC Tseng","year":"2010","unstructured":"Tseng HC, Arasteh A, Paranjpe A, Teruel A, Yang W, Behel A, Alva JA, Walter G, Head C, Ishikawa TO, Herschman HR, Cacalano N, Pyle AD, Park NH, Jewett A (2010) Increased lysis of stem cells but not their differentiated cells by natural killer cells; de-differentiation or reprogramming activates NK cells. PLoS One 5(7):e11590. doi: 10.1371\/journal.pone.0011590","journal-title":"PLoS One"},{"issue":"3","key":"1866_CR33","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1016\/j.bbrc.2007.06.094","volume":"360","author":"N Oka","year":"2007","unstructured":"Oka N, Soeda A, Inagaki A, Onodera M, Maruyama H, Hara A, Kunisada T, Mori H, Iwama T (2007) VEGF promotes tumorigenesis and angiogenesis of human glioblastoma stem cells. Biochem Biophys Res Commun 360(3):553\u2013559. doi: 10.1016\/j.bbrc.2007.06.094","journal-title":"Biochem Biophys Res Commun"},{"issue":"16","key":"1866_CR34","doi-asserted-by":"publisher","first-page":"10958","DOI":"10.1074\/jbc.M704205200","volume":"283","author":"A Soeda","year":"2008","unstructured":"Soeda A, Inagaki A, Oka N, Ikegame Y, Aoki H, Yoshimura S, Nakashima S, Kunisada T, Iwama T (2008) Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells. J Biol Chem 283(16):10958\u201310966. doi: 10.1074\/jbc.M704205200","journal-title":"J Biol Chem"},{"issue":"9","key":"1866_CR35","doi-asserted-by":"crossref","first-page":"866","DOI":"10.7150\/jca.11527","volume":"6","author":"HC Tseng","year":"2015","unstructured":"Tseng HC, Inagaki A, Bui VT, Cacalano N, Kasahara N, Man YG, Jewett A (2015) Differential targeting of stem cells and differentiated glioblastomas by NK cells. J Cancer 6(9):866\u2013876","journal-title":"J Cancer"},{"issue":"1","key":"1866_CR36","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/BF01489488","volume":"15","author":"A Jewett","year":"1995","unstructured":"Jewett A, Bonavida B (1995) Interferon-alpha activates cytotoxic function but inhibits interleukin-2-mediated proliferation and tumor necrosis factor-alpha secretion by immature human natural killer cells. J Clin Immunol 15(1):35\u201344","journal-title":"J Clin Immunol"},{"issue":"5","key":"1866_CR37","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0198-8859(03)00039-9","volume":"64","author":"A Jewett","year":"2003","unstructured":"Jewett A, Wang MY, Teruel A, Poupak Z, Bostanian Z, Park NH (2003) Cytokine dependent inverse regulation of CD54 (ICAM1) and major histocompatibility complex class I antigens by nuclear factor kappaB in HEp2 tumor cell line: effect on the function of natural killer cells. Hum Immunol 64(5):505\u2013520","journal-title":"Hum Immunol"},{"issue":"45","key":"1866_CR38","doi-asserted-by":"publisher","first-page":"3949","DOI":"10.1038\/onc.2009.252","volume":"28","author":"A Soeda","year":"2009","unstructured":"Soeda A, Park M, Lee D, Mintz A, Androutsellis-Theotokis A, McKay RD, Engh J, Iwama T, Kunisada T, Kassam AB, Pollack IF, Park DM (2009) Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha. Oncogene 28(45):3949\u20133959. doi: 10.1038\/onc.2009.252","journal-title":"Oncogene"},{"issue":"3","key":"1866_CR39","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.bbrc.2007.07.037","volume":"361","author":"A Inagaki","year":"2007","unstructured":"Inagaki A, Soeda A, Oka N, Kitajima H, Nakagawa J, Motohashi T, Kunisada T, Iwama T (2007) Long-term maintenance of brain tumor stem cell properties under at non-adherent and adherent culture conditions. Biochem Biophys Res Commun 361(3):586\u2013592","journal-title":"Biochem Biophys Res Commun"},{"issue":"5","key":"1866_CR40","doi-asserted-by":"publisher","first-page":"1693","DOI":"10.3892\/ijo.2012.1592","volume":"41","author":"X Hong","year":"2012","unstructured":"Hong X, Chedid K, Kalkanis SN (2012) Glioblastoma cell line-derived spheres in serumcontaining medium versus serum-free medium: a comparison of cancer stem cell properties. Int J Oncol 41(5):1693\u20131700. doi: 10.3892\/ijo.2012.1592","journal-title":"Int J Oncol"},{"key":"1866_CR41","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/978-94-007-6217-6_15","volume-title":"The tumor immunoenvironment","author":"A Jewett","year":"2013","unstructured":"Jewett A, Tseng HC (2013) Tumor microenvironment may shape the function and phenotype of NK cells through the induction of split anergy and generation of regulatory NK cells. In: Shurin M, Umansky V, Malyguine A (eds) The tumor immunoenvironment. Springer, Dordrecht, pp 361\u2013384"},{"issue":"3","key":"1866_CR42","doi-asserted-by":"publisher","first-page":"e9874","DOI":"10.1371\/journal.pone.0009874","volume":"5","author":"A Jewett","year":"2010","unstructured":"Jewett A, Arasteh A, Tseng HC, Behel A, Arasteh H, Yang W, Cacalano NA, Paranjpe A (2010) Strategies to rescue mesenchymal stem cells (MSCs) and dental pulp stem cells (DPSCs) from NK cell mediated cytotoxicity. PLoS One 5(3):e9874. doi: 10.1371\/journal.pone.0009874","journal-title":"PLoS One"},{"issue":"1","key":"1866_CR43","doi-asserted-by":"publisher","first-page":"12","DOI":"10.7150\/jca.5519","volume":"4","author":"A Jewett","year":"2013","unstructured":"Jewett A, Man YG, Tseng HC (2013) Dual functions of natural killer cells in selection and differentiation of stem cells; role in regulation of inflammation and regeneration of tissues. J Cancer 4(1):12\u201324. doi: 10.7150\/jca.5519","journal-title":"J Cancer"},{"issue":"2","key":"1866_CR44","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1007\/s00262-011-1163-7","volume":"61","author":"A Jewett","year":"2012","unstructured":"Jewett A, Tseng HC (2012) Potential rescue, survival and differentiation of cancer stem cells and primary non-transformed stem cells by monocyte-induced split anergy in natural killer cells. Cancer Immunol Immunother 61(2):265\u2013274. doi: 10.1007\/s00262-011-1163-7","journal-title":"Cancer Immunol Immunother"},{"issue":"1","key":"1866_CR45","doi-asserted-by":"crossref","first-page":"5","DOI":"10.2174\/156720112798375989","volume":"9","author":"A Jewett","year":"2012","unstructured":"Jewett A, Tseng HC, Arasteh A, Saadat S, Christensen RE, Cacalano NA (2012) Natural killer cells preferentially target cancer stem cells; role of monocytes in protection against NK cell mediated lysis of cancer stem cells. Curr Drug Deliv 9(1):5\u201316","journal-title":"Curr Drug Deliv"},{"issue":"4","key":"1866_CR46","doi-asserted-by":"publisher","first-page":"297","DOI":"10.3109\/1547691X.2013.877104","volume":"11","author":"A Jewett","year":"2014","unstructured":"Jewett A, Man YG, Cacalano N, Kos J, Tseng HC (2014) Natural killer cells as effectors of selection and differentiation of stem cells: role in resolution of inflammation. J Immunotoxicol 11(4):297\u2013307. doi: 10.3109\/1547691X.2013.877104","journal-title":"J Immunotoxicol"},{"issue":"10","key":"1866_CR47","doi-asserted-by":"publisher","first-page":"2393","DOI":"10.1002\/stem.188","volume":"27","author":"H Wang","year":"2009","unstructured":"Wang H, Lathia JD, Wu Q, Wang J, Li Z, Heddleston JM, Eyler CE, Elderbroom J, Gallagher J, Schuschu J, MacSwords J, Cao Y, McLendon RE, Wang XF, Hjelmeland AB, Rich JN (2009) Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth. Stem Cells 27(10):2393\u20132404. doi: 10.1002\/stem.188","journal-title":"Stem Cells"},{"issue":"1","key":"1866_CR48","doi-asserted-by":"publisher","first-page":"120","DOI":"10.3171\/jns.1992.77.1.0120","volume":"77","author":"KL Black","year":"1992","unstructured":"Black KL, Chen K, Becker DP, Merrill JE (1992) Inflammatory leukocytes associated with increased immunosuppression by glioblastoma. J Neurosurg 77(1):120\u2013126. doi: 10.3171\/jns.1992.77.1.0120","journal-title":"J Neurosurg"},{"issue":"2\u20133","key":"1866_CR49","doi-asserted-by":"publisher","first-page":"185","DOI":"10.3233\/CBM-130310","volume":"14","author":"R Chiorean","year":"2014","unstructured":"Chiorean R, Berindan-Neagoe I, Braicu C, Florian IS, Leucuta D, Crisan D, Cernea V (2014) Quantitative expression of serum biomarkers involved in angiogenesis and inflammation, in patients with glioblastoma multiforme: correlations with clinical data. Cancer Biomark 14(2\u20133):185\u2013194. doi: 10.3233\/CBM-130310","journal-title":"Cancer Biomark"},{"issue":"1","key":"1866_CR50","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/s11060-010-0290-x","volume":"102","author":"G Reynes","year":"2011","unstructured":"Reynes G, Vila V, Martin M, Parada A, Fleitas T, Reganon E, Martinez-Sales V (2011) Circulating markers of angiogenesis, inflammation, and coagulation in patients with glioblastoma. J Neurooncol 102(1):35\u201341. doi: 10.1007\/s11060-010-0290-x","journal-title":"J Neurooncol"},{"issue":"9","key":"1866_CR51","doi-asserted-by":"publisher","first-page":"e108414","DOI":"10.1371\/journal.pone.0108414","volume":"9","author":"CB Rygh","year":"2014","unstructured":"Rygh CB, Wang J, Thuen M, Gras Navarro A, Huuse EM, Thorsen F, Poli A, Zimmer J, Haraldseth O, Lie SA, Enger PO, Chekenya M (2014) Dynamic contrast enhanced MRI detects early response to adoptive NK cellular immunotherapy targeting the NG2 proteoglycan in a rat model of glioblastoma. PLoS One 9(9):e108414. doi: 10.1371\/journal.pone.0108414","journal-title":"PLoS One"},{"issue":"12","key":"1866_CR52","doi-asserted-by":"publisher","first-page":"6192","DOI":"10.4049\/jimmunol.1400859","volume":"193","author":"A Gras Navarro","year":"2014","unstructured":"Gras Navarro A, Kmiecik J, Leiss L, Zelkowski M, Engelsen A, Bruserud O, Zimmer J, Enger PO, Chekenya M (2014) NK cells with KIR2DS2 immunogenotype have a functional activation advantage to efficiently kill glioblastoma and prolong animal survival. J Immunol 193(12):6192\u20136206. doi: 10.4049\/jimmunol.1400859","journal-title":"J Immunol"}],"container-title":["Cancer Immunology, Immunotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00262-016-1866-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00262-016-1866-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00262-016-1866-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T08:27:09Z","timestamp":1692433629000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00262-016-1866-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,20]]},"references-count":52,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["1866"],"URL":"https:\/\/doi.org\/10.1007\/s00262-016-1866-x","relation":{},"ISSN":["0340-7004","1432-0851"],"issn-type":[{"value":"0340-7004","type":"print"},{"value":"1432-0851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,20]]}}}