{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T15:17:25Z","timestamp":1770909445372,"version":"3.50.1"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,9,15]],"date-time":"2017-09-15T00:00:00Z","timestamp":1505433600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100004077","name":"Kocaeli \u00dcniversitesi","doi-asserted-by":"publisher","award":["2015\/035"],"award-info":[{"award-number":["2015\/035"]}],"id":[{"id":"10.13039\/501100004077","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cancer Immunol Immunother"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1007\/s00262-017-2063-2","type":"journal-article","created":{"date-parts":[[2017,9,15]],"date-time":"2017-09-15T11:25:12Z","timestamp":1505474712000},"page":"67-77","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Monitoring the response of urothelial precancerous lesions to Bacillus Calmette-Guerin at the proteome level in an in vivo rat model"],"prefix":"10.1007","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9030-4662","authenticated-orcid":false,"given":"Kerem","family":"Teke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nil","family":"Guzel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali Kemal","family":"Uslubas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"Kasap","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasan","family":"Yilmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gurler","family":"Akpinar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Demir Kursat","family":"Yildiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ozdal","family":"Dillioglugil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,9,15]]},"reference":[{"issue":"1","key":"2063_CR1","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3322\/caac.21332","volume":"66","author":"RL Siegel","year":"2016","unstructured":"Siegel RL, Miller KD, Jemal A (2016) Cancer statistics. CA Cancer J Clin 66(1):7\u201330. doi:\n                        10.3322\/caac.21332","journal-title":"CA Cancer J Clin"},{"issue":"3","key":"2063_CR2","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1007\/s00345-009-0395-z","volume":"27","author":"KD Sievert","year":"2009","unstructured":"Sievert KD, Amend B, Nagele U, Schilling D, Bedke J, Horstmann M, Hennenlotter J, Kruck S, Stenzl A (2009) Economic aspects of bladder cancer: what are the benefits and costs? World J Urol 27(3):295\u2013300. doi:\n                        10.1007\/s00345-009-0395-z","journal-title":"World J Urol"},{"issue":"7","key":"2063_CR3","doi-asserted-by":"publisher","first-page":"2131","DOI":"10.1158\/1078-0432.CCR-09-3323","volume":"16","author":"YJ Kim","year":"2010","unstructured":"Kim YJ, Ha YS, Kim SK, Yoon HY, Lym MS, Kim MJ, Moon SK, Choi YH, Kim WJ (2010) Gene signatures for the prediction of response to Bacillus Calmette-Guerin immunotherapy in primary pT1 bladder cancers. Clin Cancer Res 16(7):2131\u20132137. doi:\n                        10.1158\/1078-0432.CCR-09-3323","journal-title":"Clin Cancer Res"},{"issue":"6 Suppl 4","key":"2063_CR4","first-page":"S199","volume":"3","author":"AR Zlotta","year":"2009","unstructured":"Zlotta AR, Fleshner NE, Jewett MA (2009) The management of BCG failure in non-muscle-invasive bladder cancer: an update. Can Urol Assoc J 3(6 Suppl 4):S199\u2013S205","journal-title":"Can Urol Assoc J"},{"issue":"Suppl 2","key":"2063_CR5","doi-asserted-by":"publisher","first-page":"S60","DOI":"10.1038\/modpathol.2008.235","volume":"22","author":"DJ Grignon","year":"2009","unstructured":"Grignon DJ (2009) The current classification of urothelial neoplasms. Mod Pathol 22(Suppl 2):S60\u2013S69. doi:\n                        10.1038\/modpathol.2008.235","journal-title":"Mod Pathol"},{"key":"2063_CR6","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1186\/1479-5876-8-122","volume":"8","author":"S Blanco","year":"2010","unstructured":"Blanco S, Raber M, Leone BE, Nespoli L, Grasso M (2010) Early detection of urothelial premalignant lesions using hexaminolevulinate fluorescence cystoscopy in high risk patients. J Transl Med 8:122. doi:\n                        10.1186\/1479-5876-8-122","journal-title":"J Transl Med"},{"issue":"4","key":"2063_CR7","doi-asserted-by":"publisher","first-page":"1571","DOI":"10.1016\/j.juro.2008.11.124","volume":"181","author":"A Bisiaux","year":"2009","unstructured":"Bisiaux A, Thiounn N, Timsit MO, Eladaoui A, Chang HH, Mapes J, Mogenet A, Bresson JL, Prie D, Bechet S, Baron C, Sadorge C, Thomas S, Albert EB, Albert PS, Albert ML (2009) Molecular analyte profiling of the early events and tissue conditioning following intravesical bacillus calmette-guerin therapy in patients with superficial bladder cancer. J Urol 181(4):1571\u20131580. doi:\n                        10.1016\/j.juro.2008.11.124","journal-title":"J Urol"},{"issue":"2","key":"2063_CR8","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1016\/j.juro.2011.10.022","volume":"187","author":"LO Reis","year":"2012","unstructured":"Reis LO, Ferreira U, Billis A, Cagnon VH, Favaro WJ (2012) Anti-angiogenic effects of the superantigen staphylococcal enterotoxin B and bacillus Calmette-Guerin immunotherapy for nonmuscle invasive bladder cancer. J Urol 187(2):438\u2013445. doi:\n                        10.1016\/j.juro.2011.10.022","journal-title":"J Urol"},{"issue":"3","key":"2063_CR9","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1538\/expanim.16-0093","volume":"66","author":"K Teke","year":"2017","unstructured":"Teke K, Ozkan TA, Cebeci OO, Yilmaz H, Keles ME, Ozkan L, Dillioglugil MO, Yildiz DK, Dillioglugil O (2017) Preventive effect of intravesical ozone supplementation on N-methyl-N-nitrosourea-induced non-muscle invasive bladder cancer in male rats. Exp Anim 66(3):191\u2013198. doi:\n                        10.1538\/expanim.16-0093","journal-title":"Exp Anim"},{"issue":"2","key":"2063_CR10","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1177\/106689690501300203","volume":"13","author":"R Montironi","year":"2005","unstructured":"Montironi R, Lopez-Beltran A (2005) The 2004 WHO classification of bladder tumors: a summary and commentary. Int J Surg Pathol 13(2):143\u2013153","journal-title":"Int J Surg Pathol"},{"issue":"6","key":"2063_CR11","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1016\/j.bbapap.2007.04.001","volume":"1774","author":"ZL Sun","year":"2007","unstructured":"Sun ZL, Zhu Y, Wang FQ, Chen R, Peng T, Fan ZN, Xu ZK, Miao Y (2007) Serum proteomic-based analysis of pancreatic carcinoma for the identification of potential cancer biomarkers. Biochim Biophys Acta 1774(6):764\u2013771. doi:\n                        10.1016\/j.bbapap.2007.04.001","journal-title":"Biochim Biophys Acta"},{"issue":"2","key":"2063_CR12","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1111\/bju.12641","volume":"115","author":"AS Andrew","year":"2015","unstructured":"Andrew AS, Gui J, Hu T, Wyszynski A, Marsit CJ, Kelsey KT, Schned AR, Tanyos SA, Pendleton EM, Ekstrom RM, Li Z, Zens MS, Borsuk M, Moore JH, Karagas MR (2015) Genetic polymorphisms modify bladder cancer recurrence and survival in a USA population-based prognostic study. BJU Int 115(2):238\u2013247. doi:\n                        10.1111\/bju.12641","journal-title":"BJU Int"},{"issue":"6","key":"2063_CR13","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1093\/carcin\/bgw033","volume":"37","author":"H Masaoka","year":"2016","unstructured":"Masaoka H, Ito H, Soga N, Hosono S, Oze I, Watanabe M, Tanaka H, Yokomizo A, Hayashi N, Eto M, Matsuo K (2016) Aldehyde dehydrogenase 2 (ALDH2) and alcohol dehydrogenase 1B (ADH1B) polymorphisms exacerbate bladder cancer risk associated with alcohol drinking: gene-environment interaction. Carcinogenesis 37(6):583\u2013588. doi:\n                        10.1093\/carcin\/bgw033","journal-title":"Carcinogenesis"},{"issue":"6","key":"2063_CR14","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1038\/aps.2012.42","volume":"33","author":"Y Pan","year":"2012","unstructured":"Pan Y, Zhong LJ, Zhou H, Wang X, Chen K, Yang HP, Xiaokaiti Y, Maimaiti A, Jiang L, Li XJ (2012) Roles of vimentin and 14-3-3 zeta\/delta in the inhibitory effects of heparin on PC-3M cell proliferation and B16-F10-luc-G5 cells metastasis. Acta Pharmacol Sin 33(6):798\u2013808. doi:\n                        10.1038\/aps.2012.42","journal-title":"Acta Pharmacol Sin"},{"issue":"9","key":"2063_CR15","doi-asserted-by":"publisher","first-page":"e24843","DOI":"10.1371\/journal.pone.0024843","volume":"6","author":"Z Wang","year":"2011","unstructured":"Wang Z, Nesland JM, Suo Z, Trope CG, Holm R (2011) The prognostic value of 14-3-3 isoforms in vulvar squamous cell carcinoma cases: 14-3-3beta and epsilon are independent prognostic factors for these tumors. PLoS One 6(9):e24843. doi:\n                        10.1371\/journal.pone.0024843","journal-title":"PLoS One"},{"issue":"1","key":"2063_CR16","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/j.eururo.2016.02.028","volume":"70","author":"PA Humphrey","year":"2016","unstructured":"Humphrey PA, Moch H, Cubilla AL, Ulbright TM, Reuter VE (2016) The 2016 WHO classification of tumours of the urinary system and male genital organs\u2014part B: prostate and bladder tumours. Eur Urol 70(1):106\u2013119. doi:\n                        10.1016\/j.eururo.2016.02.028","journal-title":"Eur Urol"},{"issue":"5","key":"2063_CR17","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1165\/rcmb.2012-0094OC","volume":"47","author":"L Du","year":"2012","unstructured":"Du L, Zhou J, Zhang J, Yan M, Gong L, Liu X, Chen M, Tao K, Luo N, Liu J (2012) Actin filament reorganization is a key step in lung inflammation induced by systemic inflammatory response syndrome. Am J Respir Cell Mol Biol 47(5):597\u2013603. doi:\n                        10.1165\/rcmb.2012-0094OC","journal-title":"Am J Respir Cell Mol Biol"},{"key":"2063_CR18","doi-asserted-by":"publisher","first-page":"15859","DOI":"10.1038\/srep15859","volume":"5","author":"S Zhang","year":"2015","unstructured":"Zhang S, Yu M, Guo Q, Li R, Li G, Tan S, Li X, Wei Y, Wu M (2015) Annexin A2 binds to endosomes and negatively regulates TLR4-triggered inflammatory responses via the TRAM-TRIF pathway. Sci Rep 5:15859. doi:\n                        10.1038\/srep15859","journal-title":"Sci Rep"},{"issue":"5","key":"2063_CR19","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1083\/jcb.201108120","volume":"196","author":"S Huveneers","year":"2012","unstructured":"Huveneers S, Oldenburg J, Spanjaard E, van der Krogt G, Grigoriev I, Akhmanova A, Rehmann H, de Rooij J (2012) Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling. J Cell Biol 196(5):641\u2013652. doi:\n                        10.1083\/jcb.201108120","journal-title":"J Cell Biol"},{"issue":"6","key":"2063_CR20","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/BF00300079","volume":"21","author":"EC Boer de","year":"1993","unstructured":"de Boer EC, De Reijke TM, Schamhart DH, Vos PC, Kurth KH (1993) Increased urinary albumin indicating urothelial leakage following intravesical bacillus Calmette-Guerin therapy for superficial bladder cancer. Urol Res 21(6):423\u2013427","journal-title":"Urol Res"},{"issue":"9","key":"2063_CR21","doi-asserted-by":"publisher","first-page":"e72917","DOI":"10.1371\/journal.pone.0072917","volume":"8","author":"CH Hsieh","year":"2013","unstructured":"Hsieh CH, Chen GC, Chen PH, Wu TF, Chao PM (2013) Altered white adipose tissue protein profile in C57BL\/6J mice displaying delipidative, inflammatory, and browning characteristics after bitter melon seed oil treatment. PLoS One 8(9):e72917. doi:\n                        10.1371\/journal.pone.0072917","journal-title":"PLoS One"},{"key":"2063_CR22","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1186\/s12885-015-1568-3","volume":"15","author":"HE Mulvey","year":"2015","unstructured":"Mulvey HE, Chang A, Adler J, Del Tatto M, Perez K, Quesenberry PJ, Chatterjee D (2015) Extracellular vesicle-mediated phenotype switching in malignant and non-malignant colon cells. BMC Cancer 15:571. doi:\n                        10.1186\/s12885-015-1568-3","journal-title":"BMC Cancer"},{"issue":"9","key":"2063_CR23","doi-asserted-by":"publisher","first-page":"2745","DOI":"10.1016\/j.jprot.2012.03.049","volume":"75","author":"VC Hodgkinson","year":"2012","unstructured":"Hodgkinson VC, Agarwal V, ELFadl D, Fox JN, McManus PL, Mahapatra TK, Kneeshaw PJ, Drew PJ, Lind MJ, Cawkwell L (2012) Pilot and feasibility study: comparative proteomic analysis by 2-DE MALDI TOF\/TOF MS reveals 14-3-3 proteins as putative biomarkers of response to neoadjuvant chemotherapy in ER-positive breast cancer. J Proteom 75(9):2745\u20132752. doi:\n                        10.1016\/j.jprot.2012.03.049","journal-title":"J Proteom"},{"issue":"11","key":"2063_CR24","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1093\/carcin\/10.11.2081","volume":"10","author":"P Campbell","year":"1989","unstructured":"Campbell P, Irving CC, Lindahl R (1989) Changes in aldehyde dehydrogenase during rat urinary bladder carcinogenesis. Carcinogenesis 10(11):2081\u20132087","journal-title":"Carcinogenesis"},{"issue":"2","key":"2063_CR25","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1158\/1055-9965.EPI-09-0865","volume":"19","author":"Y Su","year":"2010","unstructured":"Su Y, Qiu Q, Zhang X, Jiang Z, Leng Q, Liu Z, Stass SA, Jiang F (2010) Aldehyde dehydrogenase 1 A1\u2013positive cell population is enriched in tumor-initiating cells and associated with progression of bladder cancer. Cancer Epidemiol Biomark Prev 19(2):327\u2013337. doi:\n                        10.1158\/1055-9965.EPI-09-0865","journal-title":"Cancer Epidemiol Biomark Prev"},{"issue":"3","key":"2063_CR26","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.canep.2015.03.003","volume":"39","author":"N Xu","year":"2015","unstructured":"Xu N, Shao MM, Zhang HT, Jin MS, Dong Y, Ou RJ, Wang HM, Shi AP (2015) Aldehyde dehydrogenase 1 (ALDH1) expression is associated with a poor prognosis of bladder cancer. Cancer Epidemiol 39(3):375\u2013381. doi:\n                        10.1016\/j.canep.2015.03.003","journal-title":"Cancer Epidemiol"}],"container-title":["Cancer Immunology, Immunotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00262-017-2063-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00262-017-2063-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00262-017-2063-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,4]],"date-time":"2018-01-04T06:40:33Z","timestamp":1515048033000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00262-017-2063-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,15]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["2063"],"URL":"https:\/\/doi.org\/10.1007\/s00262-017-2063-2","relation":{},"ISSN":["0340-7004","1432-0851"],"issn-type":[{"value":"0340-7004","type":"print"},{"value":"1432-0851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,15]]}}}