{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T18:11:56Z","timestamp":1792087916553,"version":"4.4.0"},"reference-count":107,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2019,1,3]],"date-time":"2019-01-03T00:00:00Z","timestamp":1546473600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"LF grant","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}]},{"name":"SPORE in Skin Cancer Career Enhancement Program Award","award":["NIH P50CA121973"],"award-info":[{"award-number":["NIH P50CA121973"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cancer Immunol Immunother"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1007\/s00262-018-02296-3","type":"journal-article","created":{"date-parts":[[2019,1,3]],"date-time":"2019-01-03T04:59:15Z","timestamp":1546491555000},"page":"1819-1829","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":73,"title":["Schwann cells shape the neuro-immune environs and control cancer progression"],"prefix":"10.1007","volume":"68","author":[{"given":"German V.","family":"Martyn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Galina V.","family":"Shurin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton A.","family":"Keskinov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuri L.","family":"Bunimovich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Shurin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,1,3]]},"reference":[{"issue":"1","key":"2296_CR1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3322\/caac.21442","volume":"68","author":"RL Siegel","year":"2018","unstructured":"Siegel RL, Miller KD, Jemal A (2018) Cancer statistics, 2018. CA Cancer J Clin 68(1):7\u201330","journal-title":"CA Cancer J Clin"},{"key":"2296_CR2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2147\/ITT.S29834","volume":"1","author":"MR Shurin","year":"2012","unstructured":"Shurin MR (2012) Cancer as an immune-mediated disease. Immunotargets Ther 1:1\u20136","journal-title":"Immunotargets Ther"},{"issue":"Suppl 1","key":"2296_CR3","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s12307-009-0025-8","volume":"2","author":"IP Witz","year":"2009","unstructured":"Witz IP (2009) The tumor microenvironment: the making of a paradigm. Cancer Microenviron 2(Suppl 1):9\u201317","journal-title":"Cancer Microenviron"},{"issue":"Pt 23","key":"2296_CR4","doi-asserted-by":"crossref","first-page":"5591","DOI":"10.1242\/jcs.116392","volume":"125","author":"FR Balkwill","year":"2012","unstructured":"Balkwill FR, Capasso M, Hagemann T (2012) The tumor microenvironment at a glance. J Cell Sci 125(Pt 23):5591\u20135596","journal-title":"J Cell Sci"},{"issue":"30","key":"2296_CR5","first-page":"520","volume":"5","author":"PG McDonald","year":"2005","unstructured":"McDonald PG, Antoni MH, Lutgendorf SK, Cole SW, Dhabhar FS, Sephton SE, Stefanek M, Sood AK (2005) A biobehavioral perspective of tumor biology. Discov Med 5(30):520\u2013526","journal-title":"Discov Med"},{"issue":"6","key":"2296_CR6","first-page":"854","volume":"31","author":"JE Bruni","year":"1971","unstructured":"Bruni JE, Montemurro DG (1971) Effect of hypothalamic lesions on the genesis of spontaneous mammary gland tumors in the mouse. Cancer Res 31(6):854\u2013863","journal-title":"Cancer Res"},{"issue":"4","key":"2296_CR7","doi-asserted-by":"crossref","first-page":"430","DOI":"10.4161\/cc.6.4.3829","volume":"6","author":"PH Thaker","year":"2007","unstructured":"Thaker PH, Lutgendorf SK, Sood AK (2007) The neuroendocrine impact of chronic stress on cancer. Cell Cycle 6(4):430\u2013433","journal-title":"Cell Cycle"},{"issue":"6","key":"2296_CR8","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1007\/s12192-015-0632-x","volume":"20","author":"N Suhail","year":"2015","unstructured":"Suhail N, Bilal N, Hasan S, Ahmad A, Ashraf GM, Banu N (2015) Chronic unpredictable stress (CUS) enhances the carcinogenic potential of 7,12-dimethylbenz(a)anthracene (DMBA) and accelerates the onset of tumor development in Swiss albino mice. Cell Stress Chaperones 20(6):1023\u20131036","journal-title":"Cell Stress Chaperones"},{"issue":"3","key":"2296_CR9","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1038\/nrc1820","volume":"6","author":"MH Antoni","year":"2006","unstructured":"Antoni MH, Lutgendorf SK, Cole SW, Dhabhar FS, Sephton SE, McDonald PG, Stefanek M, Sood AK (2006) The influence of bio-behavioural factors on tumour biology: pathways and mechanisms. Nat Rev Cancer 6(3):240\u2013248","journal-title":"Nat Rev Cancer"},{"issue":"3","key":"2296_CR10","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1038\/nri1571","volume":"5","author":"R Glaser","year":"2005","unstructured":"Glaser R, Kiecolt-Glaser JK (2005) Stress-induced immune dysfunction: implications for health. Nat Rev Immunol 5(3):243\u2013251","journal-title":"Nat Rev Immunol"},{"issue":"5","key":"2296_CR11","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1158\/1078-0432.CCR-11-0641","volume":"18","author":"SW Cole","year":"2012","unstructured":"Cole SW, Sood AK (2012) Molecular pathways: beta-adrenergic signaling in cancer. Clin Cancer Res 18(5):1201\u20131206","journal-title":"Clin Cancer Res"},{"issue":"7364","key":"2296_CR12","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/nature10368","volume":"477","author":"MR Hara","year":"2011","unstructured":"Hara MR, Kovacs JJ, Whalen EJ, Rajagopal S, Strachan RT, Grant W, Towers AJ, Williams B, Lam CM, Xiao K, Shenoy SK, Gregory SG, Ahn S, Duckett DR, Lefkowitz RJ (2011) A stress response pathway regulates DNA damage through beta2-adrenoreceptors and beta-arrestin-1. Nature 477(7364):349\u2013353","journal-title":"Nature"},{"key":"2296_CR13","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/B978-0-444-52902-2.00003-5","volume":"115","author":"M Catala","year":"2013","unstructured":"Catala M, Kubis N (2013) Gross anatomy and development of the peripheral nervous system. Handb Clin Neurol 115:29\u201341","journal-title":"Handb Clin Neurol"},{"issue":"4","key":"2296_CR14","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1080\/10253890.2016.1203415","volume":"19","author":"O Krizanova","year":"2016","unstructured":"Krizanova O, Babula P, Pacak K (2016) Stress, catecholaminergic system and cancer. Stress 19(4):419\u2013428","journal-title":"Stress"},{"issue":"5","key":"2296_CR15","doi-asserted-by":"crossref","first-page":"515","DOI":"10.3892\/br.2016.625","volume":"4","author":"N Dang","year":"2016","unstructured":"Dang N, Meng X, Song H (2016) Nicotinic acetylcholine receptors and cancer. Biomed Rep 4(5):515\u2013518","journal-title":"Biomed Rep"},{"issue":"4","key":"2296_CR16","doi-asserted-by":"crossref","first-page":"e61678","DOI":"10.1371\/journal.pone.0061678","volume":"8","author":"H Nie","year":"2013","unstructured":"Nie H, Cao Q, Zhu L, Gong Y, Gu J, He Z (2013) Acetylcholine acts on androgen receptor to promote the migration and invasion but inhibit the apoptosis of human hepatocarcinoma. PLoS One 8(4):e61678","journal-title":"PLoS One"},{"issue":"6142","key":"2296_CR17","doi-asserted-by":"crossref","first-page":"1236361","DOI":"10.1126\/science.1236361","volume":"341","author":"C Magnon","year":"2013","unstructured":"Magnon C, Hall SJ, Lin J, Xue X, Gerber L, Freedland SJ, Frenette PS (2013) Autonomic nerve development contributes to prostate cancer progression. Science 341(6142):1236361","journal-title":"Science"},{"issue":"5","key":"2296_CR18","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/S0002-9394(02)01329-6","volume":"133","author":"P Seifert","year":"2002","unstructured":"Seifert P, Spitznas M (2002) Axons in human choroidal melanoma suggest the participation of nerves in the control of these tumors. Am J Ophthalmol 133(5):711\u2013713","journal-title":"Am J Ophthalmol"},{"issue":"23","key":"2296_CR19","doi-asserted-by":"crossref","first-page":"7593","DOI":"10.1158\/1078-0432.CCR-08-1164","volume":"14","author":"GE Ayala","year":"2008","unstructured":"Ayala GE, Dai H, Powell M, Li R, Ding Y, Wheeler TM, Shine D, Kadmon D, Thompson T, Miles BJ, Ittmann MM, Rowley D (2008) Cancer-related axonogenesis and neurogenesis in prostate cancer. Clin Cancer Res 14(23):7593\u20137603","journal-title":"Clin Cancer Res"},{"issue":"21","key":"2296_CR20","doi-asserted-by":"crossref","first-page":"4834","DOI":"10.1002\/cncr.26117","volume":"117","author":"D Albo","year":"2011","unstructured":"Albo D, Akay CL, Marshall CL, Wilks JA, Verstovsek G, Liu H, Agarwal N, Berger DH, Ayala GE (2011) Neurogenesis in colorectal cancer is a marker of aggressive tumor behavior and poor outcomes. Cancer 117(21):4834\u20134845","journal-title":"Cancer"},{"issue":"2","key":"2296_CR21","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1007\/s10620-011-1876-7","volume":"57","author":"T Tomita","year":"2012","unstructured":"Tomita T (2012) Localization of nerve fibers in colonic polyps, adenomas, and adenocarcinomas by immunocytochemical staining for PGP 9.5. Dig Dis Sci 57(2):364\u2013370","journal-title":"Dig Dis Sci"},{"issue":"2","key":"2296_CR22","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1046\/j.1440-1827.2001.01172.x","volume":"51","author":"T Terada","year":"2001","unstructured":"Terada T, Matsunaga Y (2001) S-100-positive nerve fibers in hepatocellular carcinoma and intrahepatic cholangiocarcinoma: an immunohistochemical study. Pathol Int 51(2):89\u201393","journal-title":"Pathol Int"},{"issue":"1","key":"2296_CR23","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1309\/2APJ-YKBD-97EH-67GW","volume":"115","author":"M Zhou","year":"2001","unstructured":"Zhou M, Patel A, Rubin MA (2001) Prevalence and location of peripheral nerve found on prostate needle biopsy. Am J Clin Pathol 115(1):39\u201343","journal-title":"Am J Clin Pathol"},{"issue":"10","key":"2296_CR24","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1097\/01.MP.0000087088.88280.B0","volume":"16","author":"LK Campbell","year":"2003","unstructured":"Campbell LK, Thomas JR, Lamps LW, Smoller BR, Folpe AL (2003) Protein gene product 9.5 (PGP 9.5) is not a specific marker of neural and nerve sheath tumors: an immunohistochemical study of 95 mesenchymal neoplasms. Mod Pathol 16(10):963\u2013969","journal-title":"Mod Pathol"},{"issue":"9","key":"2296_CR25","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nrn1746","volume":"6","author":"KR Jessen","year":"2005","unstructured":"Jessen KR, Mirsky R (2005) The origin and development of glial cells in peripheral nerves. Nat Rev Neurosci 6(9):671\u2013682","journal-title":"Nat Rev Neurosci"},{"key":"2296_CR26","doi-asserted-by":"crossref","unstructured":"Kidd GJ, Ohno N, Trapp BD (2013) Biology of Schwann cells. Handb Clin Neurol 11555\u201311579","DOI":"10.1016\/B978-0-444-52902-2.00005-9"},{"issue":"1\u20132","key":"2296_CR27","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.jns.2013.01.018","volume":"333","author":"PJ Armati","year":"2013","unstructured":"Armati PJ, Mathey EK (2013) An update on Schwann cell biology\u2013immunomodulation, neural regulation and other surprises. J Neurol Sci 333(1\u20132):68\u201372","journal-title":"J Neurol Sci"},{"key":"2296_CR28","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1146\/annurev.neuro.30.051606.094354","volume":"30","author":"ME Vargas","year":"2007","unstructured":"Vargas ME, Barres BA (2007) Why is Wallerian degeneration in the CNS so slow? Annu Rev Neurosci 30:153\u2013179","journal-title":"Annu Rev Neurosci"},{"issue":"5","key":"2296_CR29","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1002\/glia.22957","volume":"64","author":"SY Jang","year":"2016","unstructured":"Jang SY, Shin YK, Park SY, Park JY, Lee HJ, Yoo YH, Kim JK, Park HT (2016) Autophagic myelin destruction by Schwann cells during Wallerian degeneration and segmental demyelination. Glia 64(5):730\u2013742","journal-title":"Glia"},{"issue":"5","key":"2296_CR30","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s00401-015-1482-4","volume":"130","author":"P Chen","year":"2015","unstructured":"Chen P, Piao X, Bonaldo P (2015) Role of macrophages in Wallerian degeneration and axonal regeneration after peripheral nerve injury. Acta Neuropathol 130(5):605\u2013618","journal-title":"Acta Neuropathol"},{"issue":"6","key":"2296_CR31","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1242\/dmm.018184","volume":"8","author":"Y Xiao","year":"2015","unstructured":"Xiao Y, Faucherre A, Pola-Morell L, Heddleston JM, Liu TL, Chew TL, Sato F, Sehara-Fujisawa A, Kawakami K, Lopez-Schier H (2015) High-resolution live imaging reveals axon-glia interactions during peripheral nerve injury and repair in zebrafish. Dis Model Mech 8(6):553\u2013564","journal-title":"Dis Model Mech"},{"issue":"14","key":"2296_CR32","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1002\/glia.20761","volume":"56","author":"KR Jessen","year":"2008","unstructured":"Jessen KR, Mirsky R (2008) Negative regulation of myelination: relevance for development, injury, and demyelinating disease. GLIA 56(14):1552\u20131565","journal-title":"GLIA"},{"issue":"13","key":"2296_CR33","doi-asserted-by":"crossref","first-page":"3521","DOI":"10.1113\/JP270874","volume":"594","author":"KR Jessen","year":"2016","unstructured":"Jessen KR, Mirsky R (2016) The repair Schwann cell and its function in regenerating nerves. J Physiol 594(13):3521\u20133531","journal-title":"J Physiol"},{"issue":"8","key":"2296_CR34","doi-asserted-by":"crossref","first-page":"3052","DOI":"10.1523\/JNEUROSCI.22-08-03052.2002","volume":"22","author":"S Shamash","year":"2002","unstructured":"Shamash S, Reichert F, Rotshenker S (2002) The cytokine network of wallerian degeneration: tumor necrosis factor-\u03b1, interleukin-1\u03b1, and interleukin-1\u03b2. J Neurosci 22(8):3052\u20133060","journal-title":"J Neurosci"},{"issue":"4","key":"2296_CR35","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1093\/brain\/awh407","volume":"128","author":"FE Perrin","year":"2005","unstructured":"Perrin FE, Lacroix S, Avil\u00e9s-Trieueros M, David S (2005) Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1\u03b1 and interleukin-1\u03b2 Wallerian degeneration. Brain 128(4):854\u2013866","journal-title":"Brain"},{"issue":"1\u20132","key":"2296_CR36","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0165-5728(02)00003-6","volume":"124","author":"G Conti","year":"2002","unstructured":"Conti G, De Pol A, Scarpini E, Vaccina F, De Riz M, Baron P, Tiriticco M, Scarlato G (2002) Interleukin-1beta and interferon-gamma induce proliferation and apoptosis in cultured Schwann cells. J Neuroimmunol 124(1\u20132):29\u201335","journal-title":"J Neuroimmunol"},{"issue":"4","key":"2296_CR37","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/j.neuron.2011.11.031","volume":"73","author":"I Napoli","year":"2012","unstructured":"Napoli I, Noon L, Ribeiro S, Kerai A, Parrinello S, Rosenberg L, Collins M, Harrisingh M, White I, Woodhoo A, Lloyd A (2012) A central role for the ERK-signaling pathway in controlling schwann cell plasticity and peripheral nerve regeneration in vivo. Neuron 73(4):729\u2013742","journal-title":"Neuron"},{"issue":"2","key":"2296_CR38","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/0168-0102(96)01042-5","volume":"25","author":"C Ide","year":"1996","unstructured":"Ide C (1996) Peripheral nerve regeneration. Neurosci Res 25(2):101\u2013121","journal-title":"Neurosci Res"},{"key":"2296_CR39","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.neuroscience.2014.09.027","volume":"302","author":"A DeFrancesco-Lisowitz","year":"2015","unstructured":"DeFrancesco-Lisowitz A, Lindborg JA, Niemi JP, Zigmond RE (2015) The neuroimmunology of degeneration and regeneration in the peripheral nervous system. Neuroscience 302:174\u2013203","journal-title":"Neuroscience"},{"issue":"3","key":"2296_CR40","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1111\/j.1460-9568.1996.tb01237.x","volume":"8","author":"F Reichert","year":"1996","unstructured":"Reichert F, Levitzky R, Rotshenker S (1996) Interleukin 6 in intact and injured mouse peripheral nerves. Eur J Neurosci 8(3):530\u2013535","journal-title":"Eur J Neurosci"},{"issue":"4","key":"2296_CR41","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.stemcr.2014.07.014","volume":"3","author":"EC Thoma","year":"2014","unstructured":"Thoma EC, Merkl C, Heckel T, Haab R, Knoflach F, Nowaczyk C, Flint N, Jagasia R, Jensen Zoffmann S, Truong HH, Petitjean P, Jessberger S, Graf M, Iacone R (2014) Chemical conversion of human fibroblasts into functional Schwann cells. Stem Cell Reports 3(4):539\u2013547","journal-title":"Stem Cell Reports"},{"issue":"24","key":"2296_CR42","first-page":"7357","volume":"62","author":"A Chlenski","year":"2002","unstructured":"Chlenski A, Liu S, Crawford SE, Volpert OV, DeVries GH, Evangelista A, Yang Q, Salwen HR, Farrer R, Bray J, Cohn SL (2002) SPARC is a key Schwannian-derived inhibitor controlling neuroblastoma tumor angiogenesis. Cancer Res 62(24):7357\u20137363","journal-title":"Cancer Res"},{"issue":"Pt 24","key":"2296_CR43","doi-asserted-by":"crossref","first-page":"4421","DOI":"10.1242\/jcs.114.24.4421","volume":"114","author":"SE Crawford","year":"2001","unstructured":"Crawford SE, Stellmach V, Ranalli M, Huang X, Huang L, Volpert O, De Vries GH, Abramson LP, Bouck N (2001) Pigment epithelium-derived factor (PEDF) in neuroblastoma: a multifunctional mediator of Schwann cell antitumor activity. J Cell Sci 114(Pt 24):4421\u20134428","journal-title":"J Cell Sci"},{"issue":"5","key":"2296_CR44","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/0959-4388(93)90139-P","volume":"3","author":"ML Reynolds","year":"1993","unstructured":"Reynolds ML, Woolf CJ (1993) Reciprocal Schwann cell-axon interactions. Curr Opin Neurobiol 3(5):683\u2013693","journal-title":"Curr Opin Neurobiol"},{"issue":"4","key":"2296_CR45","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/0959-8049(95)00051-J","volume":"31","author":"IM Ambros","year":"1995","unstructured":"Ambros IM, Ambros PF (1995) Schwann cells in neuroblastoma. Eur J Cancer 31(4):429\u2013434","journal-title":"Eur J Cancer"},{"issue":"1","key":"2296_CR46","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1038\/s41467-017-01488-2","volume":"9","author":"V Parfejevs","year":"2018","unstructured":"Parfejevs V, Debbache J, Shakhova O, Schaefer SM, Glausch M, Wegner M, Suter U, Riekstina U, Werner S, Sommer L (2018) Injury-activated glial cells promote wound healing of the adult skin in mice. Nat Commun 9(1):236","journal-title":"Nat Commun"},{"issue":"1","key":"2296_CR47","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.neuron.2017.09.008","volume":"96","author":"MP Clements","year":"2017","unstructured":"Clements MP, Byrne E, Guerrero LF, Cattin AL, Zakka L, Ashraf A, Burden JJ, Khadayate S, Lloyd AC, Marguerat S, Parrinello S (2017) The wound microenvironment reprograms Schwann cells to invasive mesenchymal-like cells to drive peripheral nerve regeneration. Neuron 96(1):98\u2013114 e117","journal-title":"Neuron"},{"issue":"4","key":"2296_CR48","doi-asserted-by":"crossref","first-page":"2771","DOI":"10.1167\/iovs.12-10973","volume":"54","author":"C Massoll","year":"2013","unstructured":"Massoll C, Mando W, Chintala SK (2013) Excitotoxicity upregulates SARM1 protein expression and promotes Wallerian-like degeneration of retinal ganglion cells and their axons. Invest Ophthalmol Vis Sci 54(4):2771\u20132780","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"6192","key":"2296_CR49","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1126\/science.1253281","volume":"345","author":"V Dyachuk","year":"2014","unstructured":"Dyachuk V, Furlan A, Shahidi MK, Giovenco M, Kaukua N, Konstantinidou C, Pachnis V, Memic F, Marklund U, Muller T, Birchmeier C, Fried K, Ernfors P, Adameyko I (2014) Neurodevelopment. Parasympathetic neurons originate from nerve-associated peripheral glial progenitors. Science 345(6192):82\u201387","journal-title":"Science"},{"issue":"1","key":"2296_CR50","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.yexcr.2013.10.004","volume":"321","author":"M Kaucka","year":"2014","unstructured":"Kaucka M, Adameyko I (2014) Non-canonical functions of the peripheral nerve. Exp Cell Res 321(1):17\u201324","journal-title":"Exp Cell Res"},{"issue":"4","key":"2296_CR51","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1177\/0300985815616444","volume":"53","author":"RJ Pye","year":"2016","unstructured":"Pye RJ, Woods GM, Kreiss A (2016) Devil facial tumor disease. Vet Pathol 53(4):726\u2013736","journal-title":"Vet Pathol"},{"issue":"10","key":"2296_CR52","doi-asserted-by":"crossref","first-page":"3827","DOI":"10.1021\/acs.jproteome.6b00629","volume":"15","author":"N Karu","year":"2016","unstructured":"Karu N, Wilson R, Hamede R, Jones M, Woods GM, Hilder EF, Shellie RA (2016) Discovery of biomarkers for tasmanian devil cancer (DFTD) by metabolic profiling of serum. J Proteome Res 15(10):3827\u20133840","journal-title":"J Proteome Res"},{"issue":"5","key":"2296_CR53","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1111\/j.1365-2656.2007.01272.x","volume":"76","author":"S Lachish","year":"2007","unstructured":"Lachish S, Jones M, McCallum H (2007) The impact of disease on the survival and population growth rate of the tasmanian devil. J Anim Ecol 76(5):926\u2013936","journal-title":"J Anim Ecol"},{"issue":"6","key":"2296_CR54","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1354\/vp.43-6-896","volume":"43","author":"R Loh","year":"2006","unstructured":"Loh R, Hayes D, Mahjoor A, O\u2019Hara A, Pyecroft S, Raidal S (2006) The immunohistochemical characterization of devil facial tumor disease (DFTD) in the tasmanian devil (Sarcophilus harrisii). Vet Pathol 43(6):896\u2013903","journal-title":"Vet Pathol"},{"issue":"1","key":"2296_CR55","first-page":"96","volume":"121","author":"HB Clark","year":"1985","unstructured":"Clark HB, Minesky JJ, Agrawal D, Agrawal HC (1985) Myelin basic protein and P2 protein are not immunohistochemical markers for Schwann cell neoplasms. A comparative study using antisera to S-100, P2, and myelin basic proteins. Am J Pathol 121(1):96\u2013101","journal-title":"Am J Pathol"},{"issue":"5961","key":"2296_CR56","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1126\/science.1180616","volume":"327","author":"EP Murchison","year":"2010","unstructured":"Murchison EP, Tovar C, Hsu A, Bender HS, Kheradpour P, Rebbeck CA, Obendorf D, Conlan C, Bahlo M, Blizzard CA, Pyecroft S, Kreiss A, Kellis M, Stark A, Harkins TT, Marshall Graves JA, Woods GM, Hannon GJ, Papenfuss AT (2010) The tasmanian devil transcriptome reveals Schwann Cell origins of a clonally transmissible cancer. Science 327(5961):84\u201387","journal-title":"Science"},{"issue":"2","key":"2296_CR57","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.lungcan.2003.08.027","volume":"43","author":"M Gollamudi","year":"2004","unstructured":"Gollamudi M, Nethery D, Liu J, Kern JA (2004) Autocrine activation of ErbB2\/ErbB3 receptor complex by NRG-1 in non-small cell lung cancer cell lines. Lung Cancer 43(2):135\u2013143","journal-title":"Lung Cancer"},{"issue":"2","key":"2296_CR58","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1172\/JCI117001","volume":"93","author":"JA Kern","year":"1994","unstructured":"Kern JA, Slebos RJ, Top B, Rodenhuis S, Lager D, Robinson RA, Weiner D, Schwartz DA (1994) C-erbB-2 expression and codon 12 K-ras mutations both predict shortened survival for patients with pulmonary adenocarcinomas. J Clin Invest 93(2):516\u2013520","journal-title":"J Clin Invest"},{"issue":"4","key":"2296_CR59","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1165\/ajrcmb\/9.4.448","volume":"9","author":"JA Kern","year":"1993","unstructured":"Kern JA, Torney L, Weiner D, Gazdar A, Shepard HM, Fendly B (1993) Inhibition of human lung cancer cell line growth by an anti-p185HER2 antibody. Am J Respir Cell Mol Biol 9(4):448\u2013454","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"6","key":"2296_CR60","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1177\/1066896909351698","volume":"18","author":"P Pytel","year":"2010","unstructured":"Pytel P, Karrison T, Can G, Tonsgard JH, Krausz T, Montag AG (2010) Neoplasms with schwannian differentiation express transcription factors known to regulate normal schwann cell development. Int J Surg Pathol 18(6):449\u2013457","journal-title":"Int J Surg Pathol"},{"issue":"8","key":"2296_CR61","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1007\/s00262-016-1929-z","volume":"66","author":"YL Bunimovich","year":"2017","unstructured":"Bunimovich YL, Keskinov AA, Shurin GV, Shurin MR (2017) Schwann cells: a new player in the tumor microenvironment. Cancer Immunol Immunother 66(8):959\u2013968","journal-title":"Cancer Immunol Immunother"},{"issue":"6","key":"2296_CR62","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1038\/nrc3526","volume":"13","author":"NK Cheung","year":"2013","unstructured":"Cheung NK, Dyer MA (2013) Neuroblastoma: developmental biology, cancer genomics and immunotherapy. Nat Rev Cancer 13(6):397\u2013411","journal-title":"Nat Rev Cancer"},{"issue":"9579","key":"2296_CR63","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.1016\/S0140-6736(07)60983-0","volume":"369","author":"JM Maris","year":"2007","unstructured":"Maris JM, Hogarty MD, Bagatell R, Cohn SL (2007) Neuroblastoma Lancet 369(9579):2106\u20132120","journal-title":"Neuroblastoma Lancet"},{"issue":"2","key":"2296_CR64","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1002\/(SICI)1097-0142(19990715)86:2<364::AID-CNCR21>3.0.CO;2-7","volume":"86","author":"H Shimada","year":"1999","unstructured":"Shimada H, Ambros IM, Dehner LP, Hata J, Joshi VV, Roald B, Stram DO, Gerbing RB, Lukens JN, Matthay KK, Castleberry RP (1999) The international neuroblastoma pathology classification (the Shimada system). Cancer 86(2):364\u2013372","journal-title":"Cancer"},{"issue":"3","key":"2296_CR65","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/S0002-9440(10)62309-7","volume":"166","author":"S Liu","year":"2005","unstructured":"Liu S, Tian Y, Chlenski A, Yang Q, Zage P, Salwen HR, Crawford SE, Cohn SL (2005) Cross-talk between Schwann cells and neuroblasts influences the biology of neuroblastoma Xenografts. Am J Pathol 166(3):891\u2013900","journal-title":"Am J Pathol"},{"issue":"1","key":"2296_CR66","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1002\/1096-911X(20010101)36:1<163::AID-MPO1040>3.0.CO;2-2","volume":"36","author":"IM Ambros","year":"2001","unstructured":"Ambros IM, Attarbaschi A, Rumpler S, Luegmayr A, Turkof E, Gadner H, Ambros PF (2001) Neuroblastoma cells provoke Schwann cell proliferation in vitro. Med Pediatr Oncol 36(1):163\u2013168","journal-title":"Med Pediatr Oncol"},{"issue":"21","key":"2296_CR67","first-page":"5966","volume":"60","author":"D Huang","year":"2000","unstructured":"Huang D, Rutkowski JL, Brodeur GM, Chou PM, Kwiatkowski JL, Babbo A, Cohn SL (2000) Schwann cell-conditioned medium inhibits angiogenesis. Cancer Res 60(21):5966\u20135971","journal-title":"Cancer Res"},{"issue":"20","key":"2296_CR68","first-page":"4602","volume":"58","author":"JL Kwiatkowski","year":"1998","unstructured":"Kwiatkowski JL, Rutkowski JL, Yamashiro DJ, Tennekoon GI, Brodeur GM (1998) Schwann cell-conditioned medium promotes neuroblastoma survival and differentiation. Cancer Res 58(20):4602\u20134606","journal-title":"Cancer Res"},{"issue":"1","key":"2296_CR69","first-page":"504","volume":"8","author":"Y Liu","year":"2015","unstructured":"Liu Y, Song L (2015) HMGB1-induced autophagy in Schwann cells promotes neuroblastoma proliferation. Int J Clin Experiment Pathol 8(1):504\u2013510","journal-title":"Int J Clin Experiment Pathol"},{"issue":"10","key":"2296_CR70","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1038\/nrn1914","volume":"7","author":"PW Mantyh","year":"2006","unstructured":"Mantyh PW (2006) Cancer pain and its impact on diagnosis, survival and quality of life. Nat Rev Neurosci 7(10):797\u2013809","journal-title":"Nat Rev Neurosci"},{"issue":"9","key":"2296_CR71","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1093\/annonc\/mdm056","volume":"18","author":"MH Everdingen","year":"2007","unstructured":"Everdingen MH, Rijke JM, Kessels AG, Schouten HC, Kleef M, Patijn J (2007) Prevalence of pain in patients with cancer: a systematic review of the past 40 years. Ann Oncol 18(9):1437\u20131449","journal-title":"Ann Oncol"},{"issue":"3","key":"2296_CR72","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1124\/mi.10.3.7","volume":"10","author":"BL Schmidt","year":"2010","unstructured":"Schmidt BL, Hamamoto DT, Simone DA, Wilcox GL (2010) Mechanism of Cancer Pain. Mol Interven 10(3):164\u2013178","journal-title":"Mol Interven"},{"issue":"2","key":"2296_CR73","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/SPC.0000000000000048","volume":"8","author":"PW Mantyh","year":"2014","unstructured":"Mantyh PW (2014) Bone cancer pain: from mechanism to therapy. Curr Opin Support Palliat Care 8(2):83\u201390","journal-title":"Curr Opin Support Palliat Care"},{"key":"2296_CR74","first-page":"11","volume":"984570","author":"I Vendrell","year":"2015","unstructured":"Vendrell I, Macedo D, Alho I, Dionsio MR, Costa L (2015) Treatment of cancer pain by targeting cytokines. Mediat Inflam 984570:11","journal-title":"Mediat Inflam"},{"issue":"11","key":"2296_CR75","doi-asserted-by":"crossref","first-page":"2564","DOI":"10.1016\/j.pain.2011.07.020","volume":"152","author":"JM Jimenez-Andrade","year":"2011","unstructured":"Jimenez-Andrade JM, Ghilardi JR, Castaneda-Corral G, Kuskowski MA, Mantyh PW (2011) Preventive or late administration of anti-NGF therapy attenuates tumor-induced nerve sprouting, neuroma formation, and cancer pain. Pain 152(11):2564\u20132574","journal-title":"Pain"},{"issue":"5","key":"2296_CR76","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.bbi.2006.12.008","volume":"21","author":"WM Campana","year":"2007","unstructured":"Campana WM (2007) Schwann cells: activated peripheral glia and their role in neuropathic pain. Brain Behav Immun 21(5):522\u2013527","journal-title":"Brain Behav Immun"},{"issue":"8","key":"2296_CR77","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1038\/ncpneuro0262","volume":"2","author":"A Hoke","year":"2006","unstructured":"Hoke A (2006) Mechanisms of disease: what factors limit the success of peripheral nerve regeneration in humans? Nat Clin Pract Neurol 2(8):448\u2013454","journal-title":"Nat Clin Pract Neurol"},{"issue":"8","key":"2296_CR78","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/S0166-2236(00)01854-3","volume":"24","author":"LR Watkins","year":"2001","unstructured":"Watkins LR, Milligan ED, Maier SF (2001) Glial activation: a driving force for pathological pain. Trends Neurosci 24(8):450\u2013455","journal-title":"Trends Neurosci"},{"issue":"2","key":"2296_CR79","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.ejpain.2008.03.014","volume":"13","author":"A Hald","year":"2009","unstructured":"Hald A, Nedergaard S, Hansen RR, Ding M, Heegaard AM (2009) Differential activation of spinal cord glial cells in murine models of neuropathic and cancer pain. Eur J Pain 13(2):138\u2013145","journal-title":"Eur J Pain"},{"issue":"2","key":"2296_CR80","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.pain.2013.10.008","volume":"155","author":"VR Ducourneau","year":"2014","unstructured":"Ducourneau VR, Dolique T, Hachem-Delaunay S, Miraucourt LS, Amadio A, Blaszczyk L, Jacquot F, Ly J, Devoize L, Oliet SH, Dallel R, Mothet JP, Nagy F, Fenelon VS, Voisin DL (2014) Cancer pain is not necessarily correlated with spinal overexpression of reactive glia markers. Pain 155(2):275\u2013291","journal-title":"Pain"},{"issue":"11","key":"2296_CR81","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1080\/14728222.2016.1214716","volume":"20","author":"YQ Zhou","year":"2016","unstructured":"Zhou YQ, Liu Z, Liu HQ, Liu DQ, Chen SP, Ye DW, Tian YK (2016) Targeting glia for bone cancer pain. Expert Opin Ther Targets 20(11):1365\u20131374","journal-title":"Expert Opin Ther Targets"},{"issue":"6","key":"2296_CR82","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1136\/gutjnl-2015-309784","volume":"65","author":"IE Demir","year":"2016","unstructured":"Demir IE, Tieftrunk E, Schorn S, Saricaoglu OC, Pfitzinger PL, Teller S, Wang K, Waldbaur C, Kurkowski MU, Wormann SM, Shaw VE, Kehl T, Laschinger M, Costello E, Algul H, Friess H, Ceyhan GO (2016) Activated Schwann cells in pancreatic cancer are linked to analgesia via suppression of spinal astroglia and microglia. Gut 65(6):1001\u20131014","journal-title":"Gut"},{"issue":"2","key":"2296_CR83","doi-asserted-by":"crossref","first-page":"e975643","DOI":"10.4161\/23723556.2014.975643","volume":"2","author":"C Magnon","year":"2015","unstructured":"Magnon C (2015) Role of the autonomic nervous system in tumorigenesis and metastasis. Mol Cell Oncol 2(2):e975643","journal-title":"Mol Cell Oncol"},{"issue":"9","key":"2296_CR84","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1158\/0008-5472.CAN-14-3180","volume":"75","author":"P Jobling","year":"2015","unstructured":"Jobling P, Pundavela J, Oliveira SM, Roselli S, Walker MM, Hondermarck H (2015) Nerve-cancer cell cross-talk: a novel promoter of tumor progression. Cancer Res 75(9):1777\u20131781","journal-title":"Cancer Res"},{"issue":"4","key":"2296_CR85","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.3892\/ol.2013.1168","volume":"5","author":"S Li","year":"2013","unstructured":"Li S, Sun Y, Gao D (2013) Role of the nervous system in cancer metastasis. Oncol Lett 5(4):1101\u20131111","journal-title":"Oncol Lett"},{"issue":"5","key":"2296_CR86","doi-asserted-by":"crossref","first-page":"e0156095","DOI":"10.1371\/journal.pone.0156095","volume":"11","author":"AA Keskinov","year":"2016","unstructured":"Keskinov AA, Tapias V, Watkins SC, Ma Y, Shurin MR, Shurin GV (2016) Impact of the sensory neurons on melanoma growth in vivo. PLoS One 11(5):e0156095","journal-title":"PLoS One"},{"issue":"4 Pt 1","key":"2296_CR87","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1177\/000348948509400420","volume":"94","author":"JG Batsakis","year":"1985","unstructured":"Batsakis JG (1985) Nerves and neurotropic carcinomas. Ann Otol Rhinol Laryngol 94(4 Pt 1):426\u2013427","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"10","key":"2296_CR88","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/nrc3131","volume":"11","author":"AA Bapat","year":"2011","unstructured":"Bapat AA, Hostetter G, Von Hoff DD, Han H (2011) Perineural invasion and associated pain in pancreatic cancer. Nat Rev Cancer 11(10):695\u2013707","journal-title":"Nat Rev Cancer"},{"issue":"3","key":"2296_CR89","doi-asserted-by":"crossref","first-page":"335","DOI":"10.4103\/0973-029X.174630","volume":"19","author":"BK Varsha","year":"2015","unstructured":"Varsha BK, Radhika MB, Makarla S, Kuriakose MA, Kiran GS, Padmalatha GV (2015) Perineural invasion in oral squamous cell carcinoma: case series and review of literature. J Oral Maxillofac Pathol 19(3):335\u2013341","journal-title":"J Oral Maxillofac Pathol"},{"issue":"1","key":"2296_CR90","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1097\/PAS.0000000000000518","volume":"40","author":"N Knijn","year":"2016","unstructured":"Knijn N, Mogk SC, Teerenstra S, Simmer F, Nagtegaal ID (2016) Perineural invasion is a strong prognostic factor in colorectal cancer: a systematic review. Am J Surg Pathol 40(1):103\u2013112","journal-title":"Am J Surg Pathol"},{"issue":"1","key":"2296_CR91","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s13046-018-0674-x","volume":"37","author":"N Kuol","year":"2018","unstructured":"Kuol N, Stojanovska L, Apostolopoulos V, Nurgali K (2018) Role of the nervous system in cancer metastasis. J Exp Clin Cancer Res 37(1):5\u201317","journal-title":"J Exp Clin Cancer Res"},{"issue":"1","key":"2296_CR92","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s00404-015-3627-z","volume":"292","author":"L Cui","year":"2015","unstructured":"Cui L, Shi Y, Zhang GN (2015) Perineural invasion as a prognostic factor for cervical cancer: a systematic review and meta-analysis. Arch Gynecol Obstet 292(1):13\u201319","journal-title":"Arch Gynecol Obstet"},{"key":"2296_CR93","first-page":"7340180","volume":"5","author":"A Gao","year":"2016","unstructured":"Gao A, Wang L, Li J, Li H, Han Y, Ma X, Sun Y (2016) Prognostic value of perineural invasion in esophageal and esophagogastric junction carcinoma: a meta-analysis. Dis Markers 5:7340180","journal-title":"Dis Markers"},{"issue":"7","key":"2296_CR94","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1016\/j.humpath.2014.02.011","volume":"45","author":"A Olar","year":"2014","unstructured":"Olar A, He D, Florentin D, Ding Y, Ayala G (2014) Biological correlates of prostate cancer perineural invasion diameter. Human Pathol 45(7):1365\u20131369","journal-title":"Human Pathol"},{"issue":"8","key":"2296_CR95","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jnci\/dju184","volume":"106","author":"IE Demir","year":"2014","unstructured":"Demir IE, Boldis A, Pfitzinger PL, Teller S, Brunner E, Klose N, Kehl T, Maak M, Lesina M, Laschinger M, Janssen KP, Algul H, Friess H, Ceyhan GO (2014) Investigation of Schwann cells at neoplastic cell sites before the onset of cancer invasion. J Natl Cancer Inst 106(8):1","journal-title":"J Natl Cancer Inst"},{"issue":"4","key":"2296_CR96","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1172\/JCI82658","volume":"126","author":"S Deborde","year":"2016","unstructured":"Deborde S, Omelchenko T, Lyubchik A, Zhou Y, He S, McNamara WF, Chernichenko N, Lee SY, Barajas F, Chen CH, Bakst RL, Vakiani E, Hall A, Wong RJ (2016) Schwann cells induce cancer cell dispersion and invasion. J Clin Invest 126(4):1538\u20131554","journal-title":"J Clin Invest"},{"issue":"2","key":"2296_CR97","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1055\/s-0036-1571835","volume":"77","author":"RL Bakst","year":"2016","unstructured":"Bakst RL, Wong RJ (2016) Mechanisms of Perineural Invasion. J Neurol Surg B Skull Base 77(2):96\u2013106","journal-title":"J Neurol Surg B Skull Base"},{"issue":"2","key":"2296_CR98","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1002\/jcb.25300","volume":"117","author":"IC Sroka","year":"2016","unstructured":"Sroka IC, Chopra H, Das L, Gard JM, Nagle RB, Cress AE (2016) Schwann cells increase prostate and pancreatic tumor cell invasion using laminin binding A6 integrin. J Cell Biochem 117(2):491\u2013499","journal-title":"J Cell Biochem"},{"issue":"4","key":"2296_CR99","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1111\/pin.12641","volume":"68","author":"Y Fujii-Nishimura","year":"2018","unstructured":"Fujii-Nishimura Y, Yamazaki K, Masugi Y, Douguchi J, Kurebayashi Y, Kubota N, Ojima H, Kitago M, Shinoda M, Hashiguchi A, Sakamoto M (2018) Mesenchymal-epithelial transition of pancreatic cancer cells at perineural invasion sites is induced by Schwann cells. Pathol Int 68(4):214\u2013223","journal-title":"Pathol Int"},{"issue":"1","key":"2296_CR100","doi-asserted-by":"crossref","first-page":"427","DOI":"10.3892\/or.2015.4366","volume":"35","author":"C Shan","year":"2016","unstructured":"Shan C, Wei J, Hou R, Wu B, Yang Z, Wang L, Lei D, Yang X (2016) Schwann cells promote EMT and the Schwann-like differentiation of salivary adenoid cystic carcinoma cells via the BDNF\/TrkB axis. Oncol Rep 35(1):427\u2013435","journal-title":"Oncol Rep"},{"issue":"20","key":"2296_CR101","doi-asserted-by":"crossref","first-page":"5927","DOI":"10.1158\/0008-5472.CAN-18-1702","volume":"78","author":"Y Zhou","year":"2018","unstructured":"Zhou Y, Shurin GV, Zhong H, Bunimovich YL, Han B, Shurin MR (2018) Schwann cells augment cell spreading and metastasis of lung cancer. Cancer Res 78(20):5927\u20135939","journal-title":"Cancer Res"},{"issue":"6","key":"2296_CR102","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1111\/j.1471-4159.2006.04319.x","volume":"100","author":"RH Quarles","year":"2007","unstructured":"Quarles RH (2007) Myelin-associated glycoprotein (MAG): past, present and beyond. J Neurochem 100(6):1431\u20131448","journal-title":"J Neurochem"},{"key":"2296_CR103","doi-asserted-by":"crossref","first-page":"51","DOI":"10.3389\/fnmol.2015.00051","volume":"8","author":"L McKerracher","year":"2015","unstructured":"McKerracher L, Rosen KM (2015) MAG, myelin and overcoming growth inhibition in the CNS. Front Mol Neurosci 8:51\u201356","journal-title":"Front Mol Neurosci"},{"issue":"250","key":"2296_CR104","doi-asserted-by":"crossref","first-page":"250ra115","DOI":"10.1126\/scitranslmed.3009569","volume":"6","author":"CM Zhao","year":"2014","unstructured":"Zhao CM, Hayakawa Y, Kodama Y, Muthupalani S, Westphalen CB, Andersen GT, Flatberg A, Johannessen H, Friedman RA, Renz BW, Sandvik AK, Beisvag V, Tomita H, Hara A, Quante M, Li Z, Gershon MD, Kaneko K, Fox JG, Wang TC, Chen D (2014) Denervation suppresses gastric tumorigenesis. Sci Transl Med 6(250):250ra115","journal-title":"Sci Transl Med"},{"issue":"25","key":"2296_CR105","doi-asserted-by":"crossref","first-page":"S629","DOI":"10.1016\/j.ijrobp.2013.06.1664","volume":"87","author":"RL Bakst","year":"2013","unstructured":"Bakst RL, Barajas F, He S, Chernichenko N, Chen C, He S, McNamara W, Lee S, Deborde S, Wong RJ (2013) Are Schwann cells a target in radiation for perineural invasion? Int J Radiat Oncol Biol Phys 87(25):S629","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"6","key":"2296_CR106","doi-asserted-by":"crossref","first-page":"801","DOI":"10.2174\/187152710793237412","volume":"9","author":"HC Lehmann","year":"2010","unstructured":"Lehmann HC, Hoke A (2010) Schwann cells as a therapeutic target for peripheral neuropathies. CNS Neurol Disord Drug Targets 9(6):801\u2013806","journal-title":"CNS Neurol Disord Drug Targets"},{"key":"2296_CR107","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0074-7742(09)87015-3","volume":"87","author":"V Magnaghi","year":"2009","unstructured":"Magnaghi V, Procacci P, Tata AM (2009) Chap. 15: novel pharmacological approaches to Schwann cells as neuroprotective agents for peripheral nerve regeneration. Int Rev Neurobiol 87:295\u2013315","journal-title":"Int Rev Neurobiol"}],"container-title":["Cancer Immunology, Immunotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00262-018-02296-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00262-018-02296-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00262-018-02296-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T15:48:00Z","timestamp":1720885680000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00262-018-02296-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,3]]},"references-count":107,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["2296"],"URL":"https:\/\/doi.org\/10.1007\/s00262-018-02296-3","relation":{},"ISSN":["0340-7004","1432-0851"],"issn-type":[{"value":"0340-7004","type":"print"},{"value":"1432-0851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,3]]},"assertion":[{"value":"27 October 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 December 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 January 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The author reports no conflicts of interest in this work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}