{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T10:38:11Z","timestamp":1787913491759,"version":"build-2784847793"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T00:00:00Z","timestamp":1696550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T00:00:00Z","timestamp":1696550400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Bio & Medical Technology Development Program of the National Research Foundation (NRF), funded by the Korean government","award":["NRF-2020M3A9G3080281"],"award-info":[{"award-number":["NRF-2020M3A9G3080281"]}]},{"name":"Bio & Medical Technology Development Program of the National Research Foundation (NRF), funded by the Korean government","award":["NRF-2020M3A9G3080281"],"award-info":[{"award-number":["NRF-2020M3A9G3080281"]}]},{"name":"Bio & Medical Technology Development Program of the National Research Foundation (NRF), funded by the Korean government","award":["NRF-2020M3A9G3080281"],"award-info":[{"award-number":["NRF-2020M3A9G3080281"]}]},{"name":"Bio & Medical Technology Development Program of the National Research Foundation (NRF), funded by the Korean government","award":["NRF-2020M3A9G3080281"],"award-info":[{"award-number":["NRF-2020M3A9G3080281"]}]},{"name":"Bio & Medical Technology Development Program of the National Research Foundation (NRF), funded by the Korean government","award":["NRF-2020M3A9G3080281"],"award-info":[{"award-number":["NRF-2020M3A9G3080281"]}]},{"name":"Bio & Medical Technology Development Program of the National Research Foundation (NRF), funded by the Korean government","award":["NRF-2020M3A9G3080281"],"award-info":[{"award-number":["NRF-2020M3A9G3080281"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cancer Immunol Immunother"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1007\/s00262-023-03545-w","type":"journal-article","created":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T12:01:42Z","timestamp":1696593702000},"page":"4089-4102","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Intensified NK cell therapy in combination with low-dose chemoradiotherapy against human colorectal cancer"],"prefix":"10.1007","volume":"72","author":[{"given":"Huy Phuoc Quang","family":"Nguyen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woo Kyun","family":"Bae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myong Suk","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ik-Joo","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taek-Keun","family":"Nam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Uk","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tung Nguyen Thanh","family":"Uong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duck","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Ki","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meesun","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,10,6]]},"reference":[{"issue":"1","key":"3545_CR1","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1186\/s13045-022-01382-5","volume":"15","author":"N Lamers-Kok","year":"2022","unstructured":"Lamers-Kok N, Panella D, Georgoudaki AM, Liu H, \u00d6zkazanc D, Ku\u010derov\u00e1 L, Duru AD, Spanholtz J, Raimo M (2022) Natural killer cells in clinical development as non-engineered engineered and combination therapies. J Hematol Oncol 15(1):164","journal-title":"J Hematol Oncol"},{"issue":"9","key":"3545_CR2","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1016\/j.jcyt.2020.11.004","volume":"23","author":"TNT Uong","year":"2021","unstructured":"Uong TNT, Yoon MS, Lee KH, Hyun H, Nam TK, Min JJ, Nguyen HPQ, Kim SK (2021) Live cell imaging of highly activated natural killer cells against human hepatocellular carcinoma in vivo. Cytotherapy 23(9):799\u2013809","journal-title":"Cytotherapy"},{"issue":"1","key":"3545_CR3","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.ijrobp.2019.09.041","volume":"108","author":"KW Kim","year":"2020","unstructured":"Kim KW, Jeong JU, Lee KH, Uong TNT, Rhee JH, Ahn SJ, Kim SK, Cho D, Quang Nguyen HP, Pham CT, Yoon MS (2020) Combined NK cell therapy and radiation therapy exhibit long-term therapeutic and antimetastatic effects in a human triple negative breast cancer model. Int J Radiat Oncol Biol Phys 108(1):115\u2013125","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"9","key":"3545_CR4","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1016\/j.jcyt.2022.05.004","volume":"24","author":"EK Jung","year":"2022","unstructured":"Jung EK, Chu TH, Vo MC, Nguyen HPQ, Lee DH, Lee JK, Lim SC, Jung SH, Yoon TM, Yoon MS, Cho D, Lee JJ, Cho HH (2022) Natural killer cells have a synergistic anti-tumor effect in combination with chemoradiotherapy against head and neck cancer. Cytotherapy 24(9):905\u2013915","journal-title":"Cytotherapy"},{"issue":"15","key":"3545_CR5","doi-asserted-by":"publisher","first-page":"3901","DOI":"10.1158\/1078-0432.CCR-10-0735","volume":"16","author":"D Cho","year":"2010","unstructured":"Cho D, Shook DR, Shimasaki N, Chang YH, Fujisaki H, Campana D (2010) Cytotoxicity of activated natural killer cells against pediatric solid tumors. Clin Cancer Res 16(15):3901\u20133909","journal-title":"Clin Cancer Res"},{"key":"3545_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2019.107447","volume":"206","author":"S Vodenkova","year":"2020","unstructured":"Vodenkova S, Buchler T, Cervena K, Veskrnova V, Vodicka P, Vymetalkova V (2020) 5-fluorouracil and other fluoropyrimidines in colorectal cancer: past, present and future. Pharmacol Ther 206:107447","journal-title":"Pharmacol Ther"},{"key":"3545_CR7","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.ctrv.2019.04.003","volume":"76","author":"D Ciardiello","year":"2019","unstructured":"Ciardiello D, Vitiello PP, Cardone C, Martini G, Troiani T, Martinelli E, Ciardiello F (2019) Immunotherapy of colorectal cancer: challenges for therapeutic efficacy. Cancer Treat Rev 76:22\u201332","journal-title":"Cancer Treat Rev"},{"issue":"4","key":"3545_CR8","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1172\/JCI40269","volume":"120","author":"R Ramakrishnan","year":"2010","unstructured":"Ramakrishnan R, Assudani D, Nagaraj S, Hunter T, Cho HI, Antonia S, Altiok S, Celis E, Gabrilovich DI (2010) CT enhances tumor cell susceptibility to CTL-mediated killing during cancer immunotherapy in mice. J Clin Invest 120(4):1111\u20131124","journal-title":"J Clin Invest"},{"issue":"10","key":"3545_CR9","doi-asserted-by":"publisher","first-page":"3527","DOI":"10.1111\/cas.14624","volume":"111","author":"T Taniura","year":"2020","unstructured":"Taniura T, Iida Y, Kotani H, Ishitobi K, Tajima Y, Harada M (2020) Immunogenic CT in two mouse colon cancer models. Cancer Sci 111(10):3527\u20133539","journal-title":"Cancer Sci"},{"issue":"5","key":"3545_CR10","doi-asserted-by":"publisher","DOI":"10.1172\/JCI138740","volume":"131","author":"C Lhuillier","year":"2021","unstructured":"Lhuillier C, Rudqvist NP, Yamazaki T, Zhang T, Charpentier M, Galluzzi L, Dephoure N, Clement CC, Santambrogio L, Zhou XK, Formenti SC, Demaria S (2021) Radiotherapy-exposed CD8+ and CD4+ neoantigens enhance tumor control. J Clin Invest 131(5):e138740","journal-title":"J Clin Invest"},{"issue":"17","key":"3545_CR11","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1056\/NEJMoa040694","volume":"351","author":"R Sauer","year":"2004","unstructured":"Sauer R, Becker H, Hohenberger W, R\u00f6del C, Wittekind C, Fietkau R, Martus P, Tschmelitsch J, Hager E, Hess CF, Karstens JH, Liersch T, Schmidberger H, Raab R (2004) German rectal cancer study group. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 351(17):1731\u20131740","journal-title":"N Engl J Med"},{"issue":"4","key":"3545_CR12","doi-asserted-by":"publisher","first-page":"513","DOI":"10.6004\/jnccn.2014.0056","volume":"12","author":"A Cercek","year":"2014","unstructured":"Cercek A, Goodman KA, Hajj C, Weisberger E, Segal NH, Reidy-Lagunes DL, Stadler ZK, Wu AJ, Weiser MR, Paty PB, Guillem JG, Nash GM, Temple LK, Garcia-Aguilar J, Saltz LB (2014) Neoadjuvant CT first, followed by chemoradiation and then surgery, in the management of locally advanced rectal cancer. J Natl Compr Canc Netw 12(4):513\u2013519","journal-title":"J Natl Compr Canc Netw"},{"issue":"5","key":"3545_CR13","doi-asserted-by":"publisher","first-page":"1233","DOI":"10.1007\/s00262-022-03322-1","volume":"72","author":"JL Thangaraj","year":"2023","unstructured":"Thangaraj JL, Jung SH, Vo MC, Chu TH, Phan MT, Lee KH, Ahn SY, Kim M, Song GY, Ahn JS, Yang DH, Kim HJ, Cho D, Lee JJ (2023) Expanded natural killer cells potentiate the antimyeloma activity of daratumumab, lenalidomide, and dexamethasone in a myeloma xenograft model. Cancer Immunol Immunother 72(5):1233\u20131246","journal-title":"Cancer Immunol Immunother"},{"issue":"4","key":"3545_CR14","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1186\/s40425-016-0163-8","volume":"18","author":"L Van Der Kraak","year":"2016","unstructured":"Van Der Kraak L, Goel G, Ramanan K, Kaltenmeier C, Zhang L, Normolle DP, Freeman GJ, Tang D, Nason KS, Davison JM, Luketich JD, Dhupar R, Lotze MT (2016) 5-Fluorouracil upregulates cell surface B7\u2013H1 (PD-L1) expression in gastrointestinal cancers. J Immunother Cancer 18(4):65","journal-title":"J Immunother Cancer"},{"issue":"1","key":"3545_CR15","doi-asserted-by":"publisher","first-page":"1751","DOI":"10.1038\/s41467-017-01883-9","volume":"8","author":"H Sato","year":"2017","unstructured":"Sato H, Niimi A, Yasuhara T, Permata TBM, Hagiwara Y, Isono M, Nuryadi E, Sekine R, Oike T, Kakoti S, Yoshimoto Y, Held KD, Suzuki Y, Kono K, Miyagawa K, Nakano T, Shibata A (2017) DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells. Nat Commun 8(1):1751","journal-title":"Nat Commun"},{"issue":"6","key":"3545_CR16","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1038\/s41575-019-0126-x","volume":"16","author":"K Ganesh","year":"2019","unstructured":"Ganesh K, Stadler ZK, Cercek A, Mendelsohn RB, Shia J, Segal NH, Diaz LA Jr (2019) Immunotherapy in colorectal cancer: rationale, challenges and potential. Nat Rev Gastroenterol Hepatol 16(6):361\u2013375","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"14","key":"3545_CR17","doi-asserted-by":"publisher","first-page":"3837","DOI":"10.7150\/ijbs.64077","volume":"17","author":"A Fan","year":"2021","unstructured":"Fan A, Wang B, Wang X, Nie Y, Fan D, Zhao X, Lu Y (2021) Immunotherapy in colorectal cancer: current achievements and future perspective. Int J Biol Sci 17(14):3837\u20133849","journal-title":"Int J Biol Sci"},{"issue":"3","key":"3545_CR18","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2020-001610","volume":"9","author":"I Seo","year":"2021","unstructured":"Seo I, Lee HW, Byun SJ, Park JY, Min H, Lee SH, Lee JS, Kim S, Bae SU (2021) Neoadjuvant chemoradiation alters biomarkers of anticancer immunotherapy responses in locally advanced rectal cancer. J Immunother Cancer 9(3):e001610","journal-title":"J Immunother Cancer"},{"issue":"1","key":"3545_CR19","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/s13045-020-01014-w","volume":"14","author":"S Liu","year":"2021","unstructured":"Liu S, Galat V, Galat Y, Lee YKA, Wainwright D, Wu J (2021) NK cell-based cancer immunotherapy: from basic biology to clinical development. J Hematol Oncol 14(1):7","journal-title":"J Hematol Oncol"},{"issue":"1","key":"3545_CR20","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1038\/s41392-020-0110-5","volume":"5","author":"L Yang","year":"2020","unstructured":"Yang L, Shi P, Zhao G, Xu J, Peng W, Zhang J, Zhang G, Wang X, Dong Z, Chen F, Cui H (2020) Targeting cancer stem cell pathways for cancer therapy. Signal Transduct Target Ther 5(1):8","journal-title":"Signal Transduct Target Ther"},{"issue":"10","key":"3545_CR21","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.1038\/nm.4409","volume":"23","author":"E Batlle","year":"2017","unstructured":"Batlle E, Clevers H (2017) Cancer stem cells revisited. Nat Med 23(10):1124\u20131134","journal-title":"Nat Med"},{"issue":"1","key":"3545_CR22","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1186\/s12885-020-07376-1","volume":"20","author":"N Ortiz-Otero","year":"2020","unstructured":"Ortiz-Otero N, Marshall JR, Lash B, King MR (2020) Chemotherapy-induced release of circulating-tumor cells into the bloodstream in collective migration units with cancer-associated fibroblasts in metastatic cancer patients. BMC Cancer 20(1):873","journal-title":"BMC Cancer"},{"issue":"4","key":"3545_CR23","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1016\/j.immuni.2008.02.016","volume":"28","author":"N Guerra","year":"2008","unstructured":"Guerra N, Tan YX, Joncker NT, Choy A, Gallardo F, Xiong N, Knoblaugh S, Cado D, Greenberg NM, Raulet DH (2008) NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy. Immunity 28(4):571\u2013580","journal-title":"Immunity"},{"issue":"9244","key":"3545_CR24","doi-asserted-by":"publisher","first-page":"1795","DOI":"10.1016\/S0140-6736(00)03231-1","volume":"356","author":"K Imai","year":"2000","unstructured":"Imai K, Matsuyama S, Miyake S, Suga K, Nakachi K (2000) Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population. Lancet 356(9244):1795\u20131799","journal-title":"Lancet"},{"issue":"2","key":"3545_CR25","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.ccell.2017.06.009","volume":"32","author":"A L\u00f3pez-Soto","year":"2017","unstructured":"L\u00f3pez-Soto A, Gonzalez S, Smyth MJ, Galluzzi L (2017) Control of metastasis by NK cells. Cancer Cell 32(2):135\u2013154","journal-title":"Cancer Cell"},{"issue":"8","key":"3545_CR26","doi-asserted-by":"publisher","first-page":"1196","DOI":"10.1038\/s41588-021-00889-w","volume":"53","author":"M Sheffer","year":"2021","unstructured":"Sheffer M, Lowry E, Beelen N, Borah M, Amara SN, Mader CC, Roth JA, Tsherniak A, Freeman SS, Dashevsky O, Gandolfi S, Bender S, Bryan JG, Zhu C, Wang L, Tariq I, Kamath GM, Simoes RM, Dhimolea E, Yu C, Hu Y, Dufva O, Giannakis M, Syrgkanis V, Fraenkel E, Golub T, Romee R, Mustjoki S, Culhane AC, Wieten L, Mitsiades CS (2021) Genome-scale screens identify factors regulating tumor cell responses to natural killer cells. Nat Genet 53(8):1196\u20131206","journal-title":"Nat Genet"},{"issue":"7054","key":"3545_CR27","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.1038\/nature03884","volume":"436","author":"S Gasser","year":"2005","unstructured":"Gasser S, Orsulic S, Brown EJ, Raulet DH (2005) The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor. Nature 436(7054):1186\u20131190","journal-title":"Nature"},{"issue":"50","key":"3545_CR28","doi-asserted-by":"publisher","first-page":"29964","DOI":"10.1074\/jbc.M115.674010","volume":"290","author":"G Cao","year":"2015","unstructured":"Cao G, Wang J, Zheng X, Wei H, Tian Z, Sun R (2015) Tumor therapeutics work as stress inducers to enhance tumor sensitivity to natural killer (NK) cell cytolysis by up-regulating NKp30 ligand B7\u2013H6. J Biol Chem 290(50):29964\u201329973","journal-title":"J Biol Chem"},{"issue":"9","key":"3545_CR29","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1186\/1748-717X-9-49","volume":"10","author":"CH Son","year":"2014","unstructured":"Son CH, Keum JH, Yang K, Nam J, Kim MJ, Kim SH, Kang CD, Oh SO, Kim CD, Park YS, Bae J (2014) Synergistic enhancement of NK cell-mediated cytotoxicity by combination of histone deacetylase inhibitor and ionizing radiation. Radiat Oncol 10(9):49","journal-title":"Radiat Oncol"},{"issue":"3","key":"3545_CR30","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2111900119","volume":"119","author":"K Tuomela","year":"2022","unstructured":"Tuomela K, Mukherjee D, Ambrose AR, Harikrishnan A, Mole H, Hurlstone A, \u00d6nfelt B, Honeychurch J, Davis DM (2022) Radiotherapy transiently reduces the sensitivity of cancer cells to lymphocyte cytotoxicity. Proc Natl Acad Sci USA 119(3):e2111900119","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"3545_CR31","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1158\/2159-8290.CD-21-0003","volume":"12","author":"FG Herrera","year":"2022","unstructured":"Herrera FG, Ronet C, Ochoa de Olza M, Barras D, Crespo I, Andreatta M, Corria-Osorio J, Spill A, Benedetti F, Genolet R, Orcurto A, Imbimbo M, Ghisoni E, Navarro Rodrigo B, Berthold DR, Sarivalasis A, Zaman K, Duran R, Dromain C, Prior J, Schaefer N, Bourhis J, Dimopoulou G, Tsourti Z, Messemaker M, Smith T, Warren SE, Foukas P, Rusakiewicz S, Pittet MJ, Zimmermann S, Sempoux C, Dafni U, Harari A, Kandalaft LE, Carmona SJ, Dangaj Laniti D, Irving M, Coukos G (2022) Low-dose radiotherapy reverses tumor immune desertification and resistance to immunotherapy. Cancer Discov 12(1):108\u2013133","journal-title":"Cancer Discov"},{"issue":"5","key":"3545_CR32","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1016\/j.ccr.2013.09.014","volume":"24","author":"F Klug","year":"2013","unstructured":"Klug F, Prakash H, Huber PE, Seibel T, Bender N, Halama N, Pfirschke C, Voss RH, Timke C, Umansky L, Klapproth K, Sch\u00e4kel K, Garbi N, J\u00e4ger D, Weitz J, Schmitz-Winnenthal H, H\u00e4mmerling GJ, Beckhove P (2013) Low-dose irradiation programs macrophage differentiation to an iNOS+\/M1 phenotype that orchestrates effective T cell immunotherapy. Cancer Cell 24(5):589\u2013602","journal-title":"Cancer Cell"},{"issue":"12","key":"3545_CR33","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.1016\/j.jcyt.2016.08.006","volume":"18","author":"MS Yoon","year":"2016","unstructured":"Yoon MS, Pham CT, Phan MT, Shin DJ, Jang YY, Park MH, Kim SK, Kim S, Cho D (2016) Irradiation of breast cancer cells enhances CXCL16 ligand expression and induces the migration of natural killer cells expressing the CXCR6 receptor. Cytotherapy 18(12):1532\u20131542","journal-title":"Cytotherapy"},{"issue":"12","key":"3545_CR34","doi-asserted-by":"publisher","first-page":"eabh4050","DOI":"10.1126\/sciadv.abh4050","volume":"8","author":"T Walle","year":"2022","unstructured":"Walle T, Kraske JA, Liao B, Lenoir B, Timke C, von Bohlen Und Halbach E, Tran F, Griebel P, Albrecht D, Ahmed A, Suarez-Carmona M, Jim\u00e9nez-S\u00e1nchez A, Beikert T, Tietz-Dahlfu\u00df A, Menevse AN, Schmidt G, Brom M, Pahl JHW, Antonopoulos W, Miller M, Perez RL, Bestvater F, Giese NA, Beckhove P, Rosenstiel P, J\u00e4ger D, Strobel O, Pe\u2019er D, Halama N, Debus J, Cerwenka A, Huber PE (2022) Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8. Sci Adv 8(12):eabh4050","journal-title":"Sci Adv"},{"issue":"568","key":"3545_CR35","doi-asserted-by":"publisher","first-page":"eaaz5618","DOI":"10.1126\/scitranslmed.aaz5618","volume":"12","author":"F Cichocki","year":"2020","unstructured":"Cichocki F, Bjordahl R, Gaidarova S, Mahmood S, Abujarour R, Wang H, Tuininga K, Felices M, Davis ZB, Bendzick L, Clarke R, Stokely L, Rogers P, Ge M, Robinson M, Rezner B, Robbins DL, Lee TT, Kaufman DS, Blazar BR, Valamehr B, Miller JS (2020) iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti-PD-1 therapy. Sci Transl Med 4;12(568):eaaz5618.\u00a0","journal-title":"Sci Transl Med"},{"issue":"9","key":"3545_CR36","doi-asserted-by":"publisher","first-page":"1270","DOI":"10.1182\/blood-2016-03-705160","volume":"128","author":"M Gr\u00f6nholm","year":"2016","unstructured":"Gr\u00f6nholm M, Jahan F, Bryushkova EA, Madhavan S, Aglialoro F, Soto Hinojosa L, Uotila LM, Gahmberg CG (2016) LFA-1 integrin antibodies inhibit leukocyte \u03b14\u03b21-mediated adhesion by intracellular signaling. Blood 128(9):1270\u20131281.\u00a0","journal-title":"Blood"}],"container-title":["Cancer Immunology, Immunotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00262-023-03545-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00262-023-03545-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00262-023-03545-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T11:02:01Z","timestamp":1727521321000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00262-023-03545-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,6]]},"references-count":36,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["3545"],"URL":"https:\/\/doi.org\/10.1007\/s00262-023-03545-w","relation":{},"ISSN":["0340-7004","1432-0851"],"issn-type":[{"value":"0340-7004","type":"print"},{"value":"1432-0851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,6]]},"assertion":[{"value":"4 August 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 September 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 October 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no commercial, proprietary, or financial interests in the products or companies described in this article. The authors have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by the Institutional Review Board of Chonnam National University Hwasun Hospital (CNUHH-2021\u2013045). All animal procedures and experiments were approved by the Chonnam National University Institutional Animal Care and Use Committee (CNU IACUC-H-2019-7).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}