{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T10:57:32Z","timestamp":1790420252321,"version":"4.1.0"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2017,8,13]],"date-time":"2017-08-13T00:00:00Z","timestamp":1502582400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["International Orthopaedics (SICOT)"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1007\/s00264-017-3597-9","type":"journal-article","created":{"date-parts":[[2017,8,13]],"date-time":"2017-08-13T03:37:54Z","timestamp":1502595474000},"page":"2213-2220","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":96,"title":["A systematic review of the clinical applications and complications of bone marrow aspirate concentrate in management of bone defects and nonunions"],"prefix":"10.1007","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3646-809X","authenticated-orcid":false,"given":"Mohamed A.","family":"Imam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Holton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas","family":"Ernstbrunner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Pepke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Grubhofer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Narvani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martyn","family":"Snow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,8,13]]},"reference":[{"issue":"6","key":"3597_CR1","doi-asserted-by":"crossref","first-page":"940","DOI":"10.2106\/00004623-199506000-00016","volume":"77","author":"TA Einhorn","year":"1995","unstructured":"Einhorn TA (1995) Enhancement of fracture-healing. J Bone Joint Surg Am 77(6):940\u2013956","journal-title":"J Bone Joint Surg Am"},{"key":"3597_CR2","first-page":"401","volume":"45","author":"TA Einhorn","year":"1996","unstructured":"Einhorn TA (1996) Enhancement of fracture healing. Instr Course Lect 45:401\u2013416","journal-title":"Instr Course Lect"},{"issue":"Suppl","key":"3597_CR3","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1097\/00003086-199810001-00003","volume":"355","author":"TA Einhorn","year":"1998","unstructured":"Einhorn TA (1998) The cell and molecular biology of fracture healing. Clin Orthop Relat Res 355(Suppl):S7\u201321","journal-title":"Clin Orthop Relat Res"},{"issue":"6","key":"3597_CR4","first-page":"1","volume":"5","author":"Health Quality Ontario","year":"2005","unstructured":"Health Quality Ontario (2005) Osteogenic protein-1 for long bone nonunion: an evidence-based analysis. Ont Health Technol Assess Ser 5(6):1\u201357","journal-title":"Ont Health Technol Assess Ser"},{"issue":"8","key":"3597_CR5","doi-asserted-by":"publisher","first-page":"623","DOI":"10.5312\/wjo.v6.i8.623","volume":"6","author":"KM Emara","year":"2015","unstructured":"Emara KM, Diab RA, Emara AK (2015) Recent biological trends in management of fracture non-union. World J Orthop 6(8):623\u2013628. doi: 10.5312\/wjo.v6.i8.623","journal-title":"World J Orthop"},{"issue":"2","key":"3597_CR6","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1302\/0301-620X.83B2.12106","volume":"83","author":"D Hannouche","year":"2001","unstructured":"Hannouche D, Petite H, Sedel L (2001) Current trends in the enhancement of fracture healing. J Bone Joint Surg Br 83(2):157\u2013164","journal-title":"J Bone Joint Surg Br"},{"issue":"6","key":"3597_CR7","doi-asserted-by":"crossref","first-page":"355","DOI":"10.55095\/achot2014\/049","volume":"81","author":"SM Perren","year":"2014","unstructured":"Perren SM (2014) Fracture healing: fracture healing understood as the result of a fascinating cascade of physical and biological interactions. Part I. An attempt to integrate observations from 30 years AO research. Acta Chir Orthop Traumatol Cechoslov 81(6):355\u2013364","journal-title":"Acta Chir Orthop Traumatol Cechoslov"},{"issue":"Suppl 1","key":"3597_CR8","doi-asserted-by":"publisher","first-page":"99","DOI":"10.2106\/JBJS.G.01546","volume":"90","author":"BC Carofino","year":"2008","unstructured":"Carofino BC, Lieberman JR (2008) Gene therapy applications for fracture-healing. J Bone Joint Surg Am 90(Suppl 1):99\u2013110. doi: 10.2106\/JBJS.G.01546","journal-title":"J Bone Joint Surg Am"},{"issue":"Suppl","key":"3597_CR9","doi-asserted-by":"crossref","first-page":"S239","DOI":"10.1097\/00003086-199810001-00024","volume":"355","author":"S Stevenson","year":"1998","unstructured":"Stevenson S (1998) Enhancement of fracture healing with autogenous and allogeneic bone grafts. Clin Orthop Relat Res 355(Suppl):S239\u2013S246","journal-title":"Clin Orthop Relat Res"},{"issue":"3","key":"3597_CR10","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/j.1582-4934.2004.tb00320.x","volume":"8","author":"D Baksh","year":"2004","unstructured":"Baksh D, Song L, Tuan RS (2004) Adult mesenchymal stem cells: characterization, differentiation, and application in cell and gene therapy. J Cell Mol Med 8(3):301\u2013316","journal-title":"J Cell Mol Med"},{"issue":"11","key":"3597_CR11","doi-asserted-by":"publisher","first-page":"2126","DOI":"10.1177\/0363546509339582","volume":"37","author":"LV Gulotta","year":"2009","unstructured":"Gulotta LV, Kovacevic D, Ehteshami JR, Dagher E, Packer JD, Rodeo SA (2009) Application of bone marrow-derived mesenchymal stem cells in a rotator cuff repair model. Am J Sports Med 37(11):2126\u20132133. doi: 10.1177\/0363546509339582","journal-title":"Am J Sports Med"},{"issue":"6","key":"3597_CR12","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1177\/0363546509359067","volume":"38","author":"H Nejadnik","year":"2010","unstructured":"Nejadnik H, Hui JH, Feng Choong EP, Tai BC, Lee EH (2010) Autologous bone marrow-derived mesenchymal stem cells versus autologous chondrocyte implantation: an observational cohort study. Am J Sports Med 38(6):1110\u20131116. doi: 10.1177\/0363546509359067","journal-title":"Am J Sports Med"},{"key":"3597_CR13","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1051\/sicotj\/2017007","volume":"3","author":"MA Imam","year":"2017","unstructured":"Imam MA, Mahmoud SSS, Holton J, Abouelmaati D, Elsherbini Y, Snow M (2017) A systematic review of the concept and clinical applications of bone marrow aspirate concentrate in orthopaedics. SICOT-J 3:17","journal-title":"SICOT-J"},{"issue":"3","key":"3597_CR14","doi-asserted-by":"publisher","first-page":"1642","DOI":"10.3892\/mmr.2014.2358","volume":"10","author":"A Xie","year":"2014","unstructured":"Xie A, Nie L, Shen G, Cui Z, Xu P, Ge H, Tan Q (2014) The application of autologous plateletrich plasma gel in cartilage regeneration. Mol Med Rep 10(3):1642\u20131648. doi: 10.3892\/mmr.2014.2358","journal-title":"Mol Med Rep"},{"issue":"1","key":"3597_CR15","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1002\/(SICI)1097-4652(199807)176:1<57::AID-JCP7>3.0.CO;2-7","volume":"176","author":"MK Majumdar","year":"1998","unstructured":"Majumdar MK, Thiede MA, Mosca JD, Moorman M, Gerson SL (1998) Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells. J Cell Physiol 176(1):57\u201366. doi: 10.1002\/(SICI)1097-4652(199807)176:1<57::AID-JCP7>3.0.CO;2-7","journal-title":"J Cell Physiol"},{"issue":"7","key":"3597_CR16","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1302\/0301-620X.87B7.16289","volume":"87","author":"P Hernigou","year":"2005","unstructured":"Hernigou P, Poignard A, Manicom O, Mathieu G, Rouard H (2005) The use of percutaneous autologous bone marrow transplantation in nonunion and avascular necrosis of bone. J Bone Joint Surg Br Vol 87(7):896\u2013902. doi: 10.1302\/0301-620X.87B7.16289","journal-title":"J Bone Joint Surg Br Vol"},{"issue":"6","key":"3597_CR17","first-page":"711","volume":"79","author":"MS Kassem","year":"2013","unstructured":"Kassem MS (2013) Percutaneous autogenous bone marrow injection for delayed union or non union of fractures after internal fixation. Acta Orthop Belg 79(6):711\u2013717","journal-title":"Acta Orthop Belg"},{"issue":"6","key":"3597_CR18","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1007\/s00264-010-1105-6","volume":"35","author":"ST Nathan","year":"2011","unstructured":"Nathan ST, Fisher BE, Roberts CS, Giannoudis PV (2011) The management of nonunion and delayed union of patella fractures: a systematic review of the literature. Int Orthop 35(6):791\u2013795. doi: 10.1007\/s00264-010-1105-6","journal-title":"Int Orthop"},{"issue":"12","key":"3597_CR19","doi-asserted-by":"publisher","first-page":"3789","DOI":"10.1007\/s11999-014-3548-3","volume":"472","author":"DH Lee","year":"2014","unstructured":"Lee DH, Ryu KJ, Kim JW, Kang KC, Choi YR (2014) Bone marrow aspirate concentrate and platelet-rich plasma enhanced bone healing in distraction osteogenesis of the tibia. Clin Orthop Relat Res 472(12):3789\u20133797. doi: 10.1007\/s11999-014-3548-3","journal-title":"Clin Orthop Relat Res"},{"issue":"1","key":"3597_CR20","doi-asserted-by":"crossref","first-page":"34","DOI":"10.2174\/157488809787169039","volume":"4","author":"M Jager","year":"2009","unstructured":"Jager M, Jelinek EM, Wess KM, Scharfstadt A, Jacobson M, Kevy SV, Krauspe R (2009) Bone marrow concentrate: a novel strategy for bone defect treatment. Curr Stem Cell Res Ther 4(1):34\u201343","journal-title":"Curr Stem Cell Res Ther"},{"key":"3597_CR21","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1097\/00003086-200302000-00018","volume":"407","author":"GF Muschler","year":"2003","unstructured":"Muschler GF, Nitto H, Matsukura Y, Boehm C, Valdevit A, Kambic H, Davros W, Powell K, Easley K (2003) Spine fusion using cell matrix composites enriched in bone marrow-derived cells. Clin Orthop Relat Res 407:102\u2013118","journal-title":"Clin Orthop Relat Res"},{"issue":"8","key":"3597_CR22","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1002\/jor.20853","volume":"27","author":"T McCarrel","year":"2009","unstructured":"McCarrel T, Fortier L (2009) Temporal growth factor release from platelet-rich plasma, trehalose lyophilized platelets, and bone marrow aspirate and their effect on tendon and ligament gene expression. J Orthop Res 27(8):1033\u20131042. doi: 10.1002\/jor.20853","journal-title":"J Orthop Res"},{"issue":"5 Suppl","key":"3597_CR23","first-page":"s567","volume":"26","author":"RM Wilkins","year":"2003","unstructured":"Wilkins RM, Kelly CM (2003) The effect of allomatrix injectable putty on the outcome of long bone applications. Orthopedics 26(5 Suppl):s567\u2013s570","journal-title":"Orthopedics"},{"issue":"10","key":"3597_CR24","doi-asserted-by":"publisher","first-page":"1927","DOI":"10.2106\/JBJS.I.01284","volume":"92","author":"LA Fortier","year":"2010","unstructured":"Fortier LA, Potter HG, Rickey EJ, Schnabel LV, Foo LF, Chong LR, Stokol T, Cheetham J, Nixon AJ (2010) Concentrated bone marrow aspirate improves full-thickness cartilage repair compared with microfracture in the equine model. J Bone Joint Surg Am 92(10):1927\u20131937. doi: 10.2106\/JBJS.I.01284","journal-title":"J Bone Joint Surg Am"},{"issue":"10","key":"3597_CR25","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1016\/j.jclinepi.2009.06.005","volume":"62","author":"D Moher","year":"2009","unstructured":"Moher D, Liberati A, Tetzlaff J, Altman DG, Group P (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol 62(10):1006\u20131012. doi: 10.1016\/j.jclinepi.2009.06.005","journal-title":"J Clin Epidemiol"},{"issue":"7","key":"3597_CR26","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1080\/13607863.2015.1018868","volume":"19","author":"M Hyde","year":"2015","unstructured":"Hyde M, Higgs P, Wiggins RD, Blane D (2015) A decade of research using the CASP scale: key findings and future directions. Aging Ment Health 19(7):571\u2013575. doi: 10.1080\/13607863.2015.1018868","journal-title":"Aging Ment Health"},{"issue":"1","key":"3597_CR27","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/j.injury.2004.01.009","volume":"36","author":"A Goel","year":"2005","unstructured":"Goel A, Sangwan SS, Siwach RC, Ali AM (2005) Percutaneous bone marrow grafting for the treatment of tibial non-union. Injury 36(1):203\u2013206. doi: 10.1016\/j.injury.2004.01.009","journal-title":"Injury"},{"issue":"6","key":"3597_CR28","first-page":"326","volume":"55","author":"RC Siwach","year":"2001","unstructured":"Siwach RC, Sangwan SS, Singh R, Goel A (2001) Role of percutaneous bone marrow grafting in delayed unions, non-unions and poor regenerates. Indian J Med Sci 55(6):326\u2013336","journal-title":"Indian J Med Sci"},{"issue":"1","key":"3597_CR29","first-page":"10","volume":"67","author":"Y Matsuda","year":"1998","unstructured":"Matsuda Y, Sakayama K, Okumura H, Kawatani Y, Mashima N, Shibata T (1998) Percutaneous autologous bone marrow transplantation for nonunion of the femur. Nihon Geka Hokan 67(1):10\u201317","journal-title":"Nihon Geka Hokan"},{"issue":"6","key":"3597_CR30","doi-asserted-by":"crossref","first-page":"671","DOI":"10.3109\/17453679308994595","volume":"64","author":"NK Garg","year":"1993","unstructured":"Garg NK, Gaur S, Sharma S (1993) Percutaneous autogenous bone marrow grafting in 20 cases of ununited fracture. Acta Orthop Scand 64(6):671\u2013672","journal-title":"Acta Orthop Scand"},{"issue":"Suppl 1 Pt 2","key":"3597_CR31","doi-asserted-by":"publisher","first-page":"322","DOI":"10.2106\/JBJS.F.00203","volume":"88","author":"P Hernigou","year":"2006","unstructured":"Hernigou P, Mathieu G, Poignard A, Manicom O, Beaujean F, Rouard H (2006) Percutaneous autologous bone-marrow grafting for nonunions. Surgical technique. J Bone Joint Surg Am 88(Suppl 1 Pt 2):322\u2013327. doi: 10.2106\/JBJS.F.00203","journal-title":"J Bone Joint Surg Am"},{"issue":"2","key":"3597_CR32","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1007\/s11420-015-9432-1","volume":"11","author":"P Desai","year":"2015","unstructured":"Desai P, Hasan SM, Zambrana L, Hegde V, Saleh A, Cohn MR, Lane JM (2015) Bone mesenchymal stem cells with growth factors successfully treat nonunions and delayed unions. HSS J 11(2):104\u2013111. doi: 10.1007\/s11420-015-9432-1","journal-title":"HSS J"},{"key":"3597_CR33","doi-asserted-by":"publisher","unstructured":"Hernigou P, Guissou I, Homma Y, Poignard A, Chevallier N, Rouard H, Flouzat Lachaniette CH (2015) Percutaneous injection of bone marrow mesenchymal stem cells for ankle non-unions decreases complications in patients with diabetes. Int Orthop. doi: 10.1007\/s00264-015-2738-2","DOI":"10.1007\/s00264-015-2738-2"},{"issue":"7","key":"3597_CR34","doi-asserted-by":"publisher","first-page":"2301","DOI":"10.1007\/s11999-014-3637-3","volume":"472","author":"S Akcay","year":"2014","unstructured":"Akcay S, Kazimoglu C (2014) Bone marrow aspirate concentrate and platelet-rich plasma enhanced bone healing in distraction osteogenesis of the tibia. Clin Orthop Relat Res 472(7):2301\u20132302. doi: 10.1007\/s11999-014-3637-3","journal-title":"Clin Orthop Relat Res"},{"key":"3597_CR35","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1097\/00003086-200212000-00003","volume":"405","author":"P Hernigou","year":"2002","unstructured":"Hernigou P, Beaujean F (2002) Treatment of osteonecrosis with autologous bone marrow grafting. Clin Orthop Relat Res 405:14\u201323","journal-title":"Clin Orthop Relat Res"},{"issue":"2","key":"3597_CR36","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1002\/jor.21230","volume":"29","author":"M Jager","year":"2011","unstructured":"Jager M, Herten M, Fochtmann U, Fischer J, Hernigou P, Zilkens C, Hendrich C, Krauspe R (2011) Bridging the gap: bone marrow aspiration concentrate reduces autologous bone grafting in osseous defects. J Orthop Res 29(2):173\u2013180. doi: 10.1002\/jor.21230","journal-title":"J Orthop Res"},{"issue":"7","key":"3597_CR37","doi-asserted-by":"publisher","first-page":"1430","DOI":"10.2106\/JBJS.D.02215","volume":"87","author":"P Hernigou","year":"2005","unstructured":"Hernigou P, Poignard A, Beaujean F, Rouard H (2005) Percutaneous autologous bone-marrow grafting for nonunions. Influence of the number and concentration of progenitor cells. J Bone Joint Surg Am 87(7):1430\u20131437. doi: 10.2106\/JBJS.D.02215","journal-title":"J Bone Joint Surg Am"},{"issue":"11","key":"3597_CR38","doi-asserted-by":"publisher","first-page":"2231","DOI":"10.1007\/s00264-013-2087-y","volume":"37","author":"M Petri","year":"2013","unstructured":"Petri M, Namazian A, Wilke F, Ettinger M, Stubig T, Brand S, Bengel F, Krettek C, Berding G, Jagodzinski M (2013) Repair of segmental long-bone defects by stem cell concentrate augmented scaffolds: a clinical and positron emission tomography--computed tomography analysis. Int Orthop 37(11):2231\u20132237. doi: 10.1007\/s00264-013-2087-y","journal-title":"Int Orthop"},{"issue":"17\u201318","key":"3597_CR39","doi-asserted-by":"publisher","first-page":"2187","DOI":"10.1089\/ten.TEA.2010.0516","volume":"17","author":"S Sauerbier","year":"2011","unstructured":"Sauerbier S, Rickert D, Gutwald R, Nagursky H, Oshima T, Xavier SP, Christmann J, Kurz P, Menne D, Vissink A, Raghoebar G, Schmelzeisen R, Wagner W, Koch FP (2011) Bone marrow concentrate and bovine bone mineral for sinus floor augmentation: a controlled, randomized, single-blinded clinical and histological trial--per-protocol analysis. Tissue Eng A 17(17\u201318):2187\u20132197. doi: 10.1089\/ten.TEA.2010.0516","journal-title":"Tissue Eng A"},{"issue":"3","key":"3597_CR40","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1111\/j.1600-0501.2010.01981.x","volume":"22","author":"D Rickert","year":"2011","unstructured":"Rickert D, Sauerbier S, Nagursky H, Menne D, Vissink A, Raghoebar GM (2011) Maxillary sinus floor elevation with bovine bone mineral combined with either autogenous bone or autogenous stem cells: a prospective randomized clinical trial. Clin Oral Implants Res 22(3):251\u2013258. doi: 10.1111\/j.1600-0501.2010.01981.x","journal-title":"Clin Oral Implants Res"},{"issue":"4","key":"3597_CR41","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1016\/j.bone.2004.06.013","volume":"35","author":"H Kitoh","year":"2004","unstructured":"Kitoh H, Kitakoji T, Tsuchiya H, Mitsuyama H, Nakamura H, Katoh M, Ishiguro N (2004) Transplantation of marrow-derived mesenchymal stem cells and platelet-rich plasma during distraction osteogenesis--a preliminary result of three cases. Bone 35(4):892\u2013898. doi: 10.1016\/j.bone.2004.06.013","journal-title":"Bone"},{"issue":"2","key":"3597_CR42","doi-asserted-by":"publisher","first-page":"e32","DOI":"10.4081\/or.2009.e32","volume":"1","author":"C Hendrich","year":"2009","unstructured":"Hendrich C, Franz E, Waertel G, Krebs R, Jager M (2009) Safety of autologous bone marrow aspiration concentrate transplantation: initial experiences in 101 patients. Orthop Rev 1(2):e32. doi: 10.4081\/or.2009.e32","journal-title":"Orthop Rev"},{"issue":"1","key":"3597_CR43","doi-asserted-by":"publisher","first-page":"e13","DOI":"10.4081\/or.2010.e13","volume":"2","author":"S Donaldson","year":"2010","unstructured":"Donaldson S, Chundamala J, Yandow S, Wright JG (2010) Treatment for unicameral bone cysts in long bones: an evidence based review. Orthop Rev 2(1):e13. doi: 10.4081\/or.2010.e13","journal-title":"Orthop Rev"},{"issue":"11","key":"3597_CR44","doi-asserted-by":"publisher","first-page":"3047","DOI":"10.1007\/s11999-010-1430-5","volume":"468","author":"C Bella Di","year":"2010","unstructured":"Di Bella C, Dozza B, Frisoni T, Cevolani L, Donati D (2010) Injection of demineralized bone matrix with bone marrow concentrate improves healing in unicameral bone cyst. Clin Orthop Relat Res 468(11):3047\u20133055. doi: 10.1007\/s11999-010-1430-5","journal-title":"Clin Orthop Relat Res"},{"issue":"29","key":"3597_CR45","doi-asserted-by":"publisher","first-page":"3973","DOI":"10.1016\/j.biomaterials.2008.06.026","volume":"29","author":"Y Gan","year":"2008","unstructured":"Gan Y, Dai K, Zhang P, Tang T, Zhu Z, Lu J (2008) The clinical use of enriched bone marrow stem cells combined with porous beta-tricalcium phosphate in posterior spinal fusion. Biomaterials 29(29):3973\u20133982. doi: 10.1016\/j.biomaterials.2008.06.026","journal-title":"Biomaterials"},{"issue":"4","key":"3597_CR46","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1136\/jcp.2004.022178","volume":"58","author":"BJ Bain","year":"2005","unstructured":"Bain BJ (2005) Bone marrow biopsy morbidity: review of 2003. J Clin Pathol 58(4):406\u2013408. doi: 10.1136\/jcp.2004.022178","journal-title":"J Clin Pathol"},{"issue":"3","key":"3597_CR47","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1002\/ajh.20185","volume":"77","author":"CM Burkle","year":"2004","unstructured":"Burkle CM, Harrison BA, Koenig LF, Decker PA, Warner DO, Gastineau DA (2004) Morbidity and mortality of deep sedation in outpatient bone marrow biopsy. Am J Hematol 77(3):250\u2013256. doi: 10.1002\/ajh.20185","journal-title":"Am J Hematol"},{"issue":"5","key":"3597_CR48","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1111\/j.1365-2257.2004.00630.x","volume":"26","author":"BJ Bain","year":"2004","unstructured":"Bain BJ (2004) Bone marrow biopsy morbidity and mortality: 2002 data. Clin Lab Haematol 26(5):315\u2013318. doi: 10.1111\/j.1365-2257.2004.00630.x","journal-title":"Clin Lab Haematol"},{"issue":"6","key":"3597_CR49","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1046\/j.1365-2141.2003.04329.x","volume":"121","author":"BJ Bain","year":"2003","unstructured":"Bain BJ (2003) Bone marrow biopsy morbidity and mortality. Br J Haematol 121(6):949\u2013951","journal-title":"Br J Haematol"},{"issue":"11","key":"3597_CR50","doi-asserted-by":"publisher","first-page":"2377","DOI":"10.1007\/s00264-014-2343-9","volume":"38","author":"J Hernigou","year":"2014","unstructured":"Hernigou J, Picard L, Alves A, Silvera J, Homma Y, Hernigou P (2014) Understanding bone safety zones during bone marrow aspiration from the iliac crest: the sector rule. Int Orthop 38(11):2377\u20132384. doi: 10.1007\/s00264-014-2343-9","journal-title":"Int Orthop"},{"issue":"Suppl 4","key":"3597_CR51","doi-asserted-by":"publisher","first-page":"S8","DOI":"10.1016\/j.injury.2006.08.036","volume":"37","author":"EE Husebye","year":"2006","unstructured":"Husebye EE, Lyberg T, Roise O (2006) Bone marrow fat in the circulation: clinical entities and pathophysiological mechanisms. Injury 37(Suppl 4):S8\u201318. doi: 10.1016\/j.injury.2006.08.036","journal-title":"Injury"},{"issue":"10","key":"3597_CR52","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1016\/S0196-0644(89)80932-1","volume":"18","author":"JP Orlowski","year":"1989","unstructured":"Orlowski JP, Julius CJ, Petras RE, Porembka DT, Gallagher JM (1989) The safety of intraosseous infusions: risks of fat and bone marrow emboli to the lungs. Ann Emerg Med 18(10):1062\u20131067","journal-title":"Ann Emerg Med"}],"container-title":["International Orthopaedics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00264-017-3597-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00264-017-3597-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00264-017-3597-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T01:06:56Z","timestamp":1692925616000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00264-017-3597-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,13]]},"references-count":52,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["3597"],"URL":"https:\/\/doi.org\/10.1007\/s00264-017-3597-9","relation":{},"ISSN":["0341-2695","1432-5195"],"issn-type":[{"value":"0341-2695","type":"print"},{"value":"1432-5195","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,13]]}}}