{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T00:56:37Z","timestamp":1778633797108,"version":"3.51.4"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2018,3,28]],"date-time":"2018-03-28T00:00:00Z","timestamp":1522195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2018,3,28]],"date-time":"2018-03-28T00:00:00Z","timestamp":1522195200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["International Orthopaedics (SICOT)"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1007\/s00264-018-3907-x","type":"journal-article","created":{"date-parts":[[2018,3,28]],"date-time":"2018-03-28T10:12:46Z","timestamp":1522231966000},"page":"1551-1556","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Combined pharmacotherapy for osteonecrosis of the femoral head after severe acute respiratory syndrome and interstitial pneumonia: two and a half to fourteen\u00a0year follow-up"],"prefix":"10.1007","volume":"42","author":[{"given":"Weiguo","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9271-8092","authenticated-orcid":false,"given":"Nianfei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanshou","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fuqiang","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,3,28]]},"reference":[{"issue":"19","key":"3907_CR1","doi-asserted-by":"publisher","first-page":"1604","DOI":"10.2106\/JBJS.O.00071","volume":"97","author":"MA Mont","year":"2015","unstructured":"Mont MA, Cherian JJ, Sierra RJ et al (2015) Nontraumatic osteonecrosis of the femoral head: where do we stand today? A ten-year update. J Bone Joint Surg, Am 97(19):1604\u20131627","journal-title":"J Bone Joint Surg, Am"},{"issue":"3","key":"3907_CR2","doi-asserted-by":"publisher","first-page":"459","DOI":"10.2106\/00004623-199503000-00018","volume":"77","author":"MA Mont","year":"1995","unstructured":"Mont MA, Hungerford DS (1995) Non-traumatic avascular necrosis of the femoral head. J Bone Joint Surg Am 77(3):459\u2013474","journal-title":"J Bone Joint Surg Am"},{"issue":"5","key":"3907_CR3","first-page":"1117","volume":"88","author":"MA Mont","year":"2006","unstructured":"Mont MA, Jones LC, Hungerford DS et al (2006) Nontraumatic osteonecrosis of the femoral head: ten years later. J Bone Joint Surg Am 88(5):1117\u20131132","journal-title":"J Bone Joint Surg Am"},{"issue":"3","key":"3907_CR4","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1007\/s11420-016-9505-9","volume":"12","author":"JC Villa","year":"2016","unstructured":"Villa JC, Husain S, van der List JP, Gianakos A, Lane JM (2016) Treatment of pre-collapse stages of osteonecrosis of the femoral head: a systematic review of randomized control trials. HSS J 12(3):261\u2013271","journal-title":"HSS J"},{"key":"3907_CR5","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1302\/0301-620X.90B9.20056","volume":"90(9","author":"NF Zhang","year":"2008","unstructured":"Zhang NF, Li ZR, Wei HY, Liu ZH, Hernigou P (2008) Steroidinduced osteonecrosis: the number of lesions is related to the dosage. J Bone Joint Surg Br 90(9:1239\u20131243","journal-title":"J Bone Joint Surg Br"},{"issue":"6","key":"3907_CR6","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1007\/s00590-012-1054-4","volume":"23","author":"F Zhao","year":"2013","unstructured":"Zhao F, Guo K, Li Z (2013) Et al. osteonecrosis of the femoral head in SARS patients: seven years later. Eur J Orthop Surg Traumatol 23(6):671\u2013677","journal-title":"Eur J Orthop Surg Traumatol"},{"key":"3907_CR7","doi-asserted-by":"crossref","unstructured":"Glimcher MJ, & Kenzora JE (1979) The biology of osteonecrosis of the human femoral head and its clinical implications: I. Tissue biology. Clin Orthop Relat Res (138), 284\u2013309","DOI":"10.1097\/00003086-197903000-00040"},{"key":"3907_CR8","doi-asserted-by":"crossref","unstructured":"Jones JP (1992) Intravascular coagulation and osteonecrosis. Clin Orthop Relat Res (277):41\u201353","DOI":"10.1097\/00003086-199204000-00006"},{"issue":"7","key":"3907_CR9","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1517\/13543784.10.7.1309","volume":"10","author":"CJ Glueck","year":"2001","unstructured":"Glueck CJ, Freiberg RA, Fontaine RN et al (2001) Anticoagulant therapy for osteonecrosis associated with heritable hypofibrinolysis and thrombophilia. Expert Opin Investig Drugs 10(7):1309\u20131316","journal-title":"Expert Opin Investig Drugs"},{"issue":"6","key":"3907_CR10","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1007\/s00264-009-0829-7","volume":"34","author":"F Zhao","year":"2010","unstructured":"Zhao F, Li Z, Zhang N et al (2010) Lesion size changes in osteonecrosis of the femoral head: a long-term prospective study using MRI. Int Orthop 34(6):799\u2013804","journal-title":"Int Orthop"},{"issue":"12","key":"3907_CR11","doi-asserted-by":"publisher","first-page":"2589","DOI":"10.2106\/00004623-200412000-00001","volume":"86","author":"P Hernigou","year":"2004","unstructured":"Hernigou P, Poignard A, Nogier A, Manicom O (2004) Fate of very small asymptomatic stage-I Osteonecrotic lesions of the hip. J Bone Joint Surg Am 86(12):2589\u20132593","journal-title":"J Bone Joint Surg Am"},{"issue":"12","key":"3907_CR12","doi-asserted-by":"publisher","first-page":"2165","DOI":"10.2106\/JBJS.I.00575","volume":"92","author":"MA Mont","year":"2010","unstructured":"Mont MA, Zywiel MG, Marker DR, Mcgrath MS, Delanois RE (2010) The natural history of untreated asymptomatic osteonecrosis of the femoral head: a systematic literature review. J Bone Joint Surg Am 92(12):2165\u20132170","journal-title":"J Bone Joint Surg Am"},{"issue":"3","key":"3907_CR13","doi-asserted-by":"publisher","first-page":"S276","DOI":"10.21037\/cdt.2017.09.01","volume":"7","author":"J Stone","year":"2017","unstructured":"Stone J, Hangge P, Albadawi H, Wallace A, Shamoun F, Knuttien MG, Oklu R (2017) Deep vein thrombosis: pathogenesis, diagnosis, and medical management. Cardiovasc Diagn Ther 7(3):S276\u2013S284","journal-title":"Cardiovasc Diagn Ther"},{"issue":"1","key":"3907_CR14","first-page":"14","volume":"110","author":"RD Hull","year":"2013","unstructured":"Hull RD, Townshend G (2013) Long-term treatment of deep-vein thrombosis with low-molecular-weight heparin: an update of the evidence. Thromb Haemost 110(1):14\u201322","journal-title":"Thromb Haemost"},{"issue":"8","key":"3907_CR15","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1016\/j.amjmed.2011.02.033","volume":"124","author":"RD Hull","year":"2011","unstructured":"Hull RD, Liang J, Townshend G (2011) Long-term low-molecular-weight heparin and the post-thrombotic syndrome: a systematic review. Am J Med 124(8):756\u2013765","journal-title":"Am J Med"},{"key":"3907_CR16","first-page":"273","volume":"140","author":"MJ Glimcher","year":"1979","unstructured":"Glimcher MJ, Kenzora JE (1979) The biology of osteonecrosis of the human femoral head and its clinical implications. III Discussion of the etiology and genesis of thepathological sequela: comments on treatment. Clin Orthop Relat Res 140:273\u2013312","journal-title":"Clin Orthop Relat Res"},{"issue":"6","key":"3907_CR17","doi-asserted-by":"publisher","first-page":"871","DOI":"10.2106\/00004623-198870060-00012","volume":"70","author":"DJ Downey","year":"1988","unstructured":"Downey DJ, Simkin PA, Taggart R (1988) The effect of compressive loading on intraosseous pressure in the femoral head in vitro. J Bone Joint Surg Am 70(6):871\u2013877","journal-title":"J Bone Joint Surg Am"},{"issue":"2","key":"3907_CR18","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1016\/S0021-9290(98)00161-4","volume":"32","author":"SC Cowin","year":"1999","unstructured":"Cowin SC (1999) Bone poroelasticity. J Biomech 32(2):217\u2013238","journal-title":"J Biomech"},{"key":"3907_CR19","doi-asserted-by":"crossref","unstructured":"Detournay E and Cheng AH.-D. (1993) \u201cFundamentals of poroelasticity,\u201d Chapter 5 in Comprehensive Rock Engineering: Principles, Practice and Projects, Vol. II, Analysis and Design Method, ed. C. Fairhurst, Pergamon Press, pp. 113\u2013171","DOI":"10.1016\/B978-0-08-040615-2.50011-3"},{"issue":"7","key":"3907_CR20","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1002\/nag.645","volume":"32","author":"M Nuth","year":"2008","unstructured":"Nuth M, Laloui L (2008) Effective stress concept in unsaturated soils: clarification and validation of a unified framework. Int J Numer Anal Methods Geomech 32(7):771\u2013801","journal-title":"Int J Numer Anal Methods Geomech"},{"issue":"3","key":"3907_CR21","first-page":"303","volume":"22","author":"NF Zhang","year":"2008","unstructured":"Zhang NF, Qi SW, Chai JF (2008) Mechanism of \u201ccrescent sign\u201d formation in avascular necrosis of femoral head. Chin J Reparative Reconstr Surg 22(3):303\u2013306","journal-title":"Chin J Reparative Reconstr Surg"},{"issue":"12","key":"3907_CR22","doi-asserted-by":"publisher","first-page":"2692","DOI":"10.1172\/JCI118722","volume":"97","author":"GA Rodan","year":"1996","unstructured":"Rodan GA, Fleisch HA (1996) Bisphosphonates: mechanisms of action. J Clin Investig 97(12):2692\u20132696","journal-title":"J Clin Investig"},{"issue":"7","key":"3907_CR23","doi-asserted-by":"publisher","first-page":"1128","DOI":"10.1016\/j.arth.2010.11.010","volume":"26","author":"S Agarwala","year":"2011","unstructured":"Agarwala S, Shah SB (2011) Ten-year follow-up of avascular necrosis of femoral head treated with alendronate for 3 years. J Arthroplasty 26(7):1128\u20131134","journal-title":"J Arthroplasty"},{"issue":"3","key":"3907_CR24","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/j.thromres.2006.10.025","volume":"122","author":"R Rajgopal","year":"2008","unstructured":"Rajgopal R, Bear M, Butcher MK, Shaughnessy SG (2008) The effects of heparin and low molecular weight heparins on bone. Thromb Res 122(3):293\u2013298","journal-title":"Thromb Res"}],"container-title":["International Orthopaedics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00264-018-3907-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00264-018-3907-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00264-018-3907-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T05:09:36Z","timestamp":1744175376000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00264-018-3907-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,28]]},"references-count":24,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["3907"],"URL":"https:\/\/doi.org\/10.1007\/s00264-018-3907-x","relation":{},"ISSN":["0341-2695","1432-5195"],"issn-type":[{"value":"0341-2695","type":"print"},{"value":"1432-5195","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,28]]},"assertion":[{"value":"23 February 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 March 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 March 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This study was approved by the Institutional Review Board on Human Studies of the Ethical Committee of China-Japan Friendship hospital, and informed consent was obtained from all the patients.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"We did not receive any benefits directly or indirectly from commercial parties.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}