{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T09:24:27Z","timestamp":1758273867705},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2020,1,3]],"date-time":"2020-01-03T00:00:00Z","timestamp":1578009600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,1,3]],"date-time":"2020-01-03T00:00:00Z","timestamp":1578009600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["International Orthopaedics (SICOT)"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1007\/s00264-019-04419-6","type":"journal-article","created":{"date-parts":[[2020,1,3]],"date-time":"2020-01-03T05:23:32Z","timestamp":1578029012000},"page":"595-602","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The impact of intramedullary nailing on the characteristics of the pulmonary neutrophil pool in rodents"],"prefix":"10.1007","volume":"44","author":[{"given":"Michel Paul Johan","family":"Teuben","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martijn","family":"Hofman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alba","family":"Shehu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Greven","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi","family":"Qiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai Oliver","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Hildebrand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roman","family":"Pfeifer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Christoph","family":"Pape","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,1,3]]},"reference":[{"issue":"4","key":"4419_CR1","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1097\/00005373-199304000-00010","volume":"34","author":"HC Pape","year":"1993","unstructured":"Pape HC, Auf\u2018m\u2019kolk M, Paffrath T, Regel G, Sturm JA, Tscherne H (1993) Primary intramedullary femur fixation in multiple trauma patients with associated lung contusion--a cause of posttraumatic ARDS? J Trauma 34(4):540\u2013547 discussion 547-8","journal-title":"J Trauma"},{"issue":"9","key":"4419_CR2","doi-asserted-by":"publisher","first-page":"1729","DOI":"10.1007\/s00264-017-3507-1","volume":"41","author":"RH Dunn","year":"2017","unstructured":"Dunn RH, Jackson T, Burlew CC, Pieracci FM, Fox C, Cohen M, Campion EM, Lawless R, Mauffrey C (2017) Fat emboli syndrome and the orthopaedic trauma surgeon: lessons learned and clinical recommendations. Int Orthop 41(9):1729\u20131734. https:\/\/doi.org\/10.1007\/s00264-017-3507-1","journal-title":"Int Orthop"},{"issue":"4","key":"4419_CR3","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/s00068-001-1324-z","volume":"29","author":"Martijn van Griensven","year":"2003","unstructured":"van Griensven M , Krettek C, Pape HC (2003) Immune Reactions after Trauma. Eur J Trauma 29:181. https:\/\/doi.org\/10.1007\/s00068-001-1324-z","journal-title":"European Journal of Trauma"},{"issue":"9530","key":"4419_CR4","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/S0140-6736(06)69005-3","volume":"368","author":"KA Brown","year":"2006","unstructured":"Brown KA, Brain SD, Pearson JD, Edgeworth JD, Lewis SM, Treacher DF (2006) Neutrophils in development of multiple organ failure in sepsis. Lancet 368(9530):157\u2013169","journal-title":"Lancet"},{"issue":"3","key":"4419_CR5","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1097\/00024382-199409000-00012","volume":"2","author":"HC Pape","year":"1994","unstructured":"Pape HC, Remmers D, Kleemann W, Goris JA, Regel G, Tscherne H (1994) Posttraumatic multiple-organ failure-a report on clinical and autopsy findings. Shock 2(3):228\u2013234","journal-title":"Shock"},{"key":"4419_CR6","doi-asserted-by":"publisher","unstructured":"Stoermann P, Wagner N, Koehler K, Auner B, Simon TP, Pfeifer R, Horst K, Pape HC, Hildebrand F, Wutzler S, Marzi I, Relja B (2019) Monotrauma is associated with enhanced remote inflammatory response and organ damage, while polytrauma intensifies both in porcine trauma model. Eur J Trauma. https:\/\/doi.org\/10.1007\/s00068-019-01098","DOI":"10.1007\/s00068-019-01098"},{"issue":"1","key":"4419_CR7","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1186\/s12890-016-0329-7","volume":"16","author":"B Relja","year":"2016","unstructured":"Relja B, Taraki R, Teuben MP, M\u00f6rs K, Wagner N, Wutzler S, Hildebrand F, Perl M, Marzi I (2016) Sera from severe trauma patients with pneumonia and without infectious complications have differential effects on neutrophil biology. BMC Pulm Med 16(1):171","journal-title":"BMC Pulm Med"},{"issue":"1-2","key":"4419_CR8","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1016\/j.jim.2011.09.013","volume":"375","author":"KE Barletta","year":"2012","unstructured":"Barletta KE, Cagnina RE, Wallace KL, Ramos SI, Mehrad B, Linden J (2012) Leukocyte compartments in the mouse lung: distinguishing between marginated, interstitial, and alveolar cells in response to injury. J Immunol Meth 375(1-2):100\u2013110","journal-title":"J Immunol Meth"},{"issue":"3","key":"4419_CR9","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1007\/s00441-017-2748-z","volume":"371","author":"GK Aulakh","year":"2018","unstructured":"Aulakh GK (2018) Neutrophils in the lung:\u00b4the first responders\u00b4. Cell Tissue Res 371(3):577\u2013588","journal-title":"Cell Tissue Res"},{"issue":"11","key":"4419_CR10","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1016\/j.it.2018.09.002","volume":"39","author":"E Granton","year":"2018","unstructured":"Granton E, Kim JH, Podstawka J, Yipp BG (2018) The lung microvasculature is a functional immune niche. Trend Immunol 39(11):890\u2013899","journal-title":"Trend Immunol"},{"key":"4419_CR11","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1183\/09031936.95.08081275","volume":"8","author":"N Roger","year":"1995","unstructured":"Roger N, Xaubet A, Agusti C, Zabala E, Ballester E, Torres A et al (1995) Role of bronchoalveolar lavage in the diagnosis of fat embolism syndrome. Eur Respir J 8:1275\u20131280","journal-title":"Eur Respir J"},{"issue":"1","key":"4419_CR12","doi-asserted-by":"publisher","first-page":"149","DOI":"10.2106\/JBJS.H.01141","volume":"92","author":"M Blankstein","year":"2010","unstructured":"Blankstein M, Byrick RJ, Nakane M, Bang KW, Freedman J, Richards RR et al (2010) Amplified inflammatory response to sequential hemorrhage, resuscitation, and pulmonary fatembolism: an animal study. JBJS Am 92(1):149\u2013161. https:\/\/doi.org\/10.2106\/JBJS.H.01141","journal-title":"JBJS Am"},{"issue":"1","key":"4419_CR13","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1002\/jor.1100020115","volume":"2","author":"F Bonnarens","year":"1984","unstructured":"Bonnarens F, Einhorn TH (1984) Production of a standard closed fracture in laboratory animal bone. J Orthop Res 2(1):97\u2013101","journal-title":"J Orthop Res"},{"issue":"1","key":"4419_CR14","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1097\/SHK.0b013e31815d190b","volume":"30","author":"P Kobbe","year":"2008","unstructured":"Kobbe P, Vodovotz Y, Kaczorowski DJ, Mollen KP, Billiar TR, Pape HC (2008) Patterns of cytokine release and evolution of remote organ dysfunction after bilateral femur fracture. Shock 30(1):43\u201347","journal-title":"Shock"},{"issue":"2","key":"4419_CR15","first-page":"145","volume":"48","author":"S Skrajnar","year":"2009","unstructured":"Skrajnar S, Anzur Lasnik M, Bedina Zavec A (2009) A flow cytometric method for determination of the blood neutrophil fraction in rats. J Am Lab Anim Sci 48(2):145\u2013156","journal-title":"J Am Lab Anim Sci"},{"issue":"4","key":"4419_CR16","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1182\/blood.V82.4.1097.1097","volume":"82","author":"SI Simon","year":"1993","unstructured":"Simon SI, Rochon YP, Lynam EB, Smith CW, Anderson DC, Sklar LA (1993) Beta 2-integrin and L-selectin ae obligatory receptors in neutrophil aggregation. Blood 82(4):1097\u20131106","journal-title":"Blood"},{"issue":"3","key":"4419_CR17","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1007\/s00441-017-2774-x","volume":"371","author":"A Ivetic","year":"2018","unstructured":"Ivetic A (2018) A head-to-tail view of L-selectin and its impact on neutrophil behavior. Cell Tiss Res 371(3):437\u2013453","journal-title":"Cell Tiss Res"},{"key":"4419_CR18","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1165\/ajrcmb\/8.6.633","volume":"8","author":"SP Neeley","year":"1993","unstructured":"Neeley SP, Hamann KJ, White SR, Baranowski SL, Burch RA, Leff AR (1993) Selective regulation of expression of surface adhesion molecules Mac-1, L-selectin, and VLA-4 on human eosinophils and neutrophils. Am J Respir Cell Mol Biol 8:633\u2013639","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"1","key":"4419_CR19","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1097\/TA.0b013e3182789489","volume":"74","author":"KJP van Wessem","year":"2013","unstructured":"van Wessem KJP, Heeres M, Leliefeld PHC, Koenderman L, Leenen LPH (2013) Lipopolysaccharide and hemorragic shock cause systemic inflammation by different mechanisms. J Trauma 74(1):37\u201344","journal-title":"J Trauma"},{"issue":"1","key":"4419_CR20","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1172\/JCI57990","volume":"122","author":"J Pillay","year":"2012","unstructured":"Pillay J, Kamp VM, van Hoffen E, Visser T, Tak T, Lammers JW, Ulfman LH, Leenen LP, Pickkers P, Koederman L (2012) A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1. J Clinic Invest 122(1):327\u2013336","journal-title":"J Clinic Invest"},{"issue":"1","key":"4419_CR21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/00005373-199807000-00001","volume":"45","author":"RA Cocks","year":"1998","unstructured":"Cocks RA, Chan TY, Rainer TH (1998) Leukocyte L-selectin is up-regulated after mechanical trauma in adults. J Trauma 45(1):1\u20136","journal-title":"J Trauma"},{"issue":"24","key":"4419_CR22","doi-asserted-by":"publisher","first-page":"5640","DOI":"10.1182\/blood-2012-01-380121","volume":"119","author":"P Bruhns","year":"2012","unstructured":"Bruhns P (2012) Properties of mouse and human IgG receptors and their contribution to disease models. Blood 119(24):5640\u20135649","journal-title":"Blood"},{"key":"4419_CR23","doi-asserted-by":"publisher","first-page":"157","DOI":"10.3389\/fimmu.2012.00157","volume":"3","author":"CT Lefort","year":"2012","unstructured":"Lefort CT, Ley K (2012) Neutrophil arrest by LFA-1. Front Immunol 3:157","journal-title":"Front Immunol"},{"issue":"1","key":"4419_CR24","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1097\/SHK.0b013e318295a40a","volume":"40","author":"F Hietbrink","year":"2013","unstructured":"Hietbrink F, Koenderman L, Althuizen M, Pillay J, Kamp V, Leenen LPH (2013) Kinetics of the innate immune response after trauma: implications for the development of late onset sepsis. Shock 40(1):21\u201327","journal-title":"Shock"},{"issue":"2","key":"4419_CR25","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/0022-4804(91)90090-9","volume":"51","author":"BO Anderson","year":"1991","unstructured":"Anderson BO, Brown JM, Harken AH (1991) Mechanisms of neutrophil-mediated tissue injury. J Surg Res 51(2):170\u2013179","journal-title":"J Surg Res"}],"container-title":["International Orthopaedics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00264-019-04419-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00264-019-04419-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00264-019-04419-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,2]],"date-time":"2021-01-02T00:14:36Z","timestamp":1609546476000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00264-019-04419-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,3]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["4419"],"URL":"https:\/\/doi.org\/10.1007\/s00264-019-04419-6","relation":{},"ISSN":["0341-2695","1432-5195"],"issn-type":[{"value":"0341-2695","type":"print"},{"value":"1432-5195","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,3]]},"assertion":[{"value":"21 June 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 September 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 January 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}