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We estimated the incidence and severity of fractures in France regardless of the anatomical site.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Observational cross-sectional study in France in 2016 based on the national health data system. All incident fractures in patients 20\u00a0years and older were included. We determined the anatomical fracture site (12 sites) and the severity using a 4-point scale (outpatient care, hospitalization, surgery, and in-hospital death).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We identified 562,094 incident fractures, predominantly occurring in women (319,858: 56.9%); with a mean age of 63.6\u00a0years, and an exponential increase after the age of 70\u00a0years. Distal upper limb (172,591: 30.7%), distal lower limb (84,602: 15.1%), and femoral neck (78,766: 14.0%) accounted for more than one-half of all fractures. Sex and age of onset distributions varied widely according to fracture sites, with earlier onset for distal lower limb fractures (mean age: 54.2\u00a0years) and distal upper limb fractures (mean age: 55.2\u00a0years) with a men predominance for skull fractures. Only 105,165 (18.7%) fractures were treated on an outpatient basis; 11,913 (2.1%) in-hospital deaths occurred in patients with a mean age of 79.5\u00a0years. High mortality was observed for skull (12.9%), rib (4.9%), and femoral fractures (femoral neck 4.3% and proximal lower limb 4.2%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We estimated the incidence of fractures in France by sex and anatomical site. We also showed that fractures remain common and serious life events, especially in older people.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00264-020-04492-2","type":"journal-article","created":{"date-parts":[[2020,2,8]],"date-time":"2020-02-08T01:02:32Z","timestamp":1581123752000},"page":"947-955","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Burden of fractures in France: incidence and severity by age, gender, and site in 2016"],"prefix":"10.1007","volume":"44","author":[{"given":"Benjamin","family":"Bouyer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanny","family":"Leroy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00e9mie","family":"Rudant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Weill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7674-7192","authenticated-orcid":false,"given":"Jo\u00ebl","family":"Coste","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,2,8]]},"reference":[{"key":"4492_CR1","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1016\/S8756-3282(01)00614-7","volume":"29","author":"TP van Staa","year":"2001","unstructured":"van Staa TP, Dennison EM, Leufkens HG, Cooper C (2001) Epidemiology of fractures in England and Wales. 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