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Our research had been approved by the IRB of the authors\u2019 affiliated institutions. Our study was registered on the website clinicaltrial.gov, the registration number was ClinicalTrials.gov Identifier: NCT04756947. Data acquisition and analysis had been concordant with the STROBE protocol.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Written informed consent (signed by parents) had been gained prior to enrollment to this clinical trial.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Written informed consent (signed by parents) had been gained prior to the publication of clinical data.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"There were no prior publications or submissions with any overlapping information, including studies and patients.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosure of prior publications or submissions"}}]}}