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Between 2007 and 2018, 36 TKA procedures were performed on 28 consecutive patients with a diagnosis of lymphoedema and lipoedema. Oxford Knee Scores (OKS), EuroQol-5D (EQ-5D) scores, satisfaction scores, radiographs, and complications were obtained at the final follow-up. Patients were admitted to the hospital up to two\u00a0weeks prior to surgery and remained on the ward for daily compression bandaging by the specialist lymphoedema team.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Over the study period, 36 TKAs were performed on 28 patients (5 males, 23 females) with a mean age of 71\u00a0years (range 54\u201390). Of these, 30 TKAs were in patients with lymphoedema, five with lipoedema, and one with a dual diagnosis. Overall, 28 TKAs (21 patients) were available at the final follow-up with a mean follow-up time of 61\u00a0months (range 9\u2013138). The mean BMI was 38.5\u00a0kg\/m<jats:sup>2<\/jats:sup>. The mean pre-operative and post-operative Oxford Knee Score increased from 18 (range 2\u201338) to 29 (range 10\u201354); <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001. EQ-5D score increased from 0.48 (range 0.15\u20130.80) to 0.74 (0.34\u20131.00) (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Mean post-operative satisfaction was 7.6\/10 (range 2\u201310), with 89.3% TKAs satisfied. Complications were one (4%, 1\/28) deep vein thrombosis, one superficial wound infection, one prosthetic joint infection, one stiff knee requiring manipulation, and one intra-operative femoral fracture.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Lymphoedema and lipoedema should not be seen as barriers to TKA if adopting a multidisciplinary approach.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00264-022-05575-y","type":"journal-article","created":{"date-parts":[[2022,9,8]],"date-time":"2022-09-08T17:03:53Z","timestamp":1662656633000},"page":"2815-2820","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Five-year results after total knee arthroplasty in lymphoedema and lipoedema: encouraging functional and clinical outcomes and low rates of infection"],"prefix":"10.1007","volume":"46","author":[{"given":"Luke","family":"Granger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott M.","family":"Bolam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avtar","family":"Sur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Hutt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nemandra A.","family":"Sandiford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,9,8]]},"reference":[{"key":"5575_CR1","unstructured":"The National Joint Registry. 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