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Retroperitoneoscopic debridement offers a minimally invasive approach to manage LTB, potentially reducing complications and recovery time compared to traditional open surgery. However, its efficacy and safety remain understudied. This retrospective cohort study aims to evaluate the clinical outcomes, complication rates, and long-term effectiveness of retroperitoneoscopic debridement in patients with LTB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study analyzed patients with LTB and treated with retroperitoneoscopic debridement at our institution from July 2022 to July 2023. Baseline patient characteristics, operative time, operative blood loss, changes in inflammatory markers (e.g., CRP, ESR), complication rates, the visual analog scale (VAS) scores of the back, Oswestry Disability Index (ODI) scores, kyphotic angle changes in infective level and radiological follow-up outcomes were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty patients with LTB were finally included. The mean operative time, operative blood loss, and postoperative drainage volume were 88.42\u2009\u00b1\u20097.07\u00a0min, 26.32\u2009\u00b1\u200910.61\u00a0ml, and 58.00\u2009\u00b1\u200911.31 ml, respectively. The mean follow-up time was 20.21\u2009\u00b1\u20091.41\u00a0months. During the follow-up, both VAS score and ODI score were significantly improved at one\u00a0month, three\u00a0months postoperative, and the final follow-up, compared with preoperative (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). At the final follow-up, the kyphotic angle in the infective level remained good in all patients and no spinal instability was observed. Bone graft fusion rate at the final follow-up was 100%. Compared with preoperative, ESR and CRP were both showed significant decrease at one and three\u00a0months postoperative (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). One patient was found with postoperative complications, and cured after active treatment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Retroperitoneoscopic debridement appears to be a safe and effective minimally invasive approach for treating LTB. However, long-term efficacy requires further validation through prospective studies with larger sample sizes and extended follow-up periods.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00264-026-06803-5","type":"journal-article","created":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T06:36:39Z","timestamp":1776926199000},"page":"1135-1144","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of the efficacy of retroperitoneoscopic debridement for lumbar tuberculosis: a retrospective study and preliminary results"],"prefix":"10.1007","volume":"50","author":[{"given":"Yongrui","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenkai","family":"Ruan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianlong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongpan","family":"Dang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huigang","family":"An","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wentao","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingxin","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongdong","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,23]]},"reference":[{"issue":"11","key":"6803_CR1","doi-asserted-by":"publisher","first-page":"1858","DOI":"10.1016\/j.spinee.2019.05.002","volume":"19","author":"K Khanna","year":"2019","unstructured":"Khanna K, Sabharwal S (2019) Spinal tuberculosis: a comprehensive review for the modern spine surgeon. 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All authors are in agreement with the manuscript.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The portions of this study involving human participants, human materials. or human data were conducted in accordance with the Declaration of Helsinki and were approved by the Ethics committee of Shandong Public Health Clinical Center, Shandong University (approval number K2025137). All patients provided written informed consent, explicitly informed that the study aims to investigate the application and efficacy of retroperitoneoscopic debridement in lumbar infectious spondylodiscitis.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this research and any accompanying images.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}