{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T19:26:09Z","timestamp":1792697169410,"version":"4.5.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2006,10,31]],"date-time":"2006-10-31T00:00:00Z","timestamp":1162252800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aesth Plast Surg"],"published-print":{"date-parts":[[2006,12]]},"DOI":"10.1007\/s00266-006-0081-0","type":"journal-article","created":{"date-parts":[[2006,10,31]],"date-time":"2006-10-31T11:26:38Z","timestamp":1162293998000},"page":"689-694","source":"Crossref","is-referenced-by-count":45,"title":["Anti-androgenic Therapy Using Oral Spironolactone for Acne Vulgaris in Asians"],"prefix":"10.1007","volume":"30","author":[{"given":"Katsujiro","family":"Sato","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiko","family":"Iizuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emiko","family":"Aiba-Kojima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asami","family":"Watanabe-Ono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotaka","family":"Suga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keita","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichi","family":"Gonda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kotaro","family":"Yoshimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,10,31]]},"reference":[{"key":"81_CR1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1001\/archderm.1982.01650130027012","volume":"118","author":"BS Allen","year":"1982","unstructured":"Allen BS, Smith JG Jr: Various parameters for grading acne vulgaris. Arch Dermatol 118:23\u201325, 1982","journal-title":"Arch Dermatol"},{"key":"81_CR2","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/S0015-0282(16)54290-3","volume":"55","author":"E Carmina","year":"1991","unstructured":"Carmina E, Stanczyk FZ, Matteri RK, Lobo RA: Serum androsterone conjugates differentiate between acne and hirsutism in hyperandrogenic women. Fertil Steril 55:872\u2013876, 1991","journal-title":"Fertil Steril"},{"key":"81_CR3","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1046\/j.1440-0960.2003.00653.x","volume":"44","author":"AJ Cooper","year":"2003","unstructured":"Cooper AJ: Treatment of acne with isotretinoin: Recommendations based on Australian experience. Australian Roaccutane Advisory Board. Australas J Dermatol 44:97\u2013105, 2003","journal-title":"Australas J Dermatol"},{"key":"81_CR4","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1111\/j.1365-2133.1997.tb08748.x","volume":"136","author":"V Goulden","year":"1997","unstructured":"Goulden V, Clark SM, Cunliffe WJ: Postadolescent acne: A review of clinical features. Br J Dermatol 136:66\u201370, 1997","journal-title":"Br J Dermatol"},{"key":"81_CR5","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1034\/j.1600-0773.2001.d01-108.x","volume":"88","author":"P Kasper","year":"2001","unstructured":"Kasper P: Cyproterone acetate: A genotoxic carcinogen? Pharmacol Toxicol 88:223\u2013231, 2001","journal-title":"Pharmacol Toxicol"},{"key":"81_CR6","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1111\/1523-1747.ep12539043","volume":"81","author":"AW Lucky","year":"1983","unstructured":"Lucky AW, McGuire J, Rosenfield RL, Lucky PA, Rich BH: Plasma androgens in women with acne vulgaris. J Invest Dermatol 81:70\u201374, 1983","journal-title":"J Invest Dermatol"},{"key":"81_CR7","first-page":"95","volume":"38","author":"T Masahashi","year":"1986","unstructured":"Masahashi T, Wu MC, Ohsawa M, Asai M, Ichikawa Y, Hanai K, Kikkawa H, Mizutani S, Narita O, Tomoda Y: Spironolactone therapy for hyperandrogenic anovulatory women: Clinical and endocrinological study. Nippon Sanka Fujinka Gakkai Zasshi 38:95\u2013101, 1986","journal-title":"Nippon Sanka Fujinka Gakkai Zasshi"},{"key":"81_CR8","first-page":"49","volume":"32","author":"M Messina","year":"1990","unstructured":"Messina M, Manieri C, Musso MC, Pastorino R: Oral and topical spironolactone therapies in skin androgenization. Panminerva Med 32:49\u201355, 1990","journal-title":"Panminerva Med"},{"key":"81_CR9","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1365-2133.1986.tb05722.x","volume":"115","author":"MF Muhlemann","year":"1986","unstructured":"Muhlemann MF, Carter GD, Cream JJ, Wise P: Oral spironolactone: An effective treatment for acne vulgaris in women. Br J Dermatol 115:227\u2013232, 1986","journal-title":"Br J Dermatol"},{"key":"81_CR10","first-page":"213","volume":"38","author":"PP Ng","year":"1999","unstructured":"Ng PP, Goh CL: Treatment outcome of acne vulgaris with oral isotretinoin in 89 patients. Int J Dermatol 38:213\u2013216, 1999","journal-title":"Int J Dermatol"},{"key":"81_CR11","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1111\/j.1464-410X.1991.tb15142.x","volume":"67","author":"BT Parys","year":"1991","unstructured":"Parys BT, Hamid S, Thomson RG: Severe hepatocellular dysfunction following cyproterone acetate therapy. Br J Urol 67:312\u2013313, 1991","journal-title":"Br J Urol"},{"key":"81_CR12","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0960-0760(02)00154-1","volume":"82","author":"T Satoh","year":"2002","unstructured":"Satoh T, Itoh S, Seki T, Itoh S, Nomura N, Yoshizawa I: On the inhibitory action of 29 drugs having side effect gynecomastia on estrogen production. J Steroid Biochem Mol Biol 82:209\u2013216, 2002","journal-title":"J Steroid Biochem Mol Biol"},{"key":"81_CR13","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1067\/mjd.2000.105557","volume":"43","author":"JC Shaw","year":"2000","unstructured":"Shaw JC: Low-dose adjunctive spironolactone in the treatment of acne in women: A retrospective analysis of 85 consecutively treated patients. J Am Acad Dermatol 43:498\u2013502, 2000","journal-title":"J Am Acad Dermatol"},{"key":"81_CR14","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1177\/120347540200600604","volume":"6","author":"JC Shaw","year":"2002","unstructured":"Shaw JC, White LE: Long-term safety of spironolactone in acne: Results of an 8-year follow-up study. J Cutan Med Surg 6:541\u2013545, 2002","journal-title":"J Cutan Med Surg"},{"key":"81_CR15","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/S0015-0282(01)01701-0","volume":"75","author":"SM Slayden","year":"2001","unstructured":"Slayden SM, Moran C, Sams WM Jr, Boots LR, Azziz R: Hyperandrogenemia in patients presenting with acne. Fertil Steril 75:889\u2013892, 2001","journal-title":"Fertil Steril"},{"key":"81_CR16","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1248\/bpb.26.1455","volume":"26","author":"E Takashima","year":"2003","unstructured":"Takashima E, Iguchi K, Usui S, Yamamoto H, Hirano K: Metabolite profiles of flutamide-induced hepatic dysfunction. Biol Pharm Bull 26:1455\u20131460, 2003","journal-title":"Biol Pharm Bull"},{"key":"81_CR17","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1159\/000067823","volume":"206","author":"D Thiboutot","year":"2003","unstructured":"Thiboutot D, Chen W: Update and future of hormonal therapy in acne. Dermatology 206:57\u201367, 2003","journal-title":"Dermatology"},{"key":"81_CR18","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/1523-1747.ep12874121","volume":"94","author":"P Vexiau","year":"1990","unstructured":"Vexiau P, Husson C, Chivot M, Brerault JL, Fiet J, Julien R, Villette JM, Hardy N, Cathelineau G: Androgen excess in women with acne alone compared with women with acne and\/or hirsutism. J Invest Dermatol 94:279\u2013283, 1990","journal-title":"J Invest Dermatol"},{"key":"81_CR19","doi-asserted-by":"crossref","first-page":"860","DOI":"10.7326\/0003-4819-118-11-199306010-00006","volume":"118","author":"DK Wysowski","year":"1993","unstructured":"Wysowski DK, Freiman JP, Tourtelot JB, Horton ML III: Fatal and nonfatal hepatotoxicity associated with flutamide. Ann Intern Med 118:860\u2013864, 1993","journal-title":"Ann Intern Med"},{"key":"81_CR20","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1159\/000067821","volume":"206","author":"CC Zouboulis","year":"2003","unstructured":"Zouboulis CC, Martin JP: Update and future systemic acne treatment. Dermatology 206:37\u201353, 2003","journal-title":"Dermatology"}],"container-title":["Aesthetic Plastic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00266-006-0081-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00266-006-0081-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00266-006-0081-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T13:01:48Z","timestamp":1558702908000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00266-006-0081-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,31]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["81"],"URL":"https:\/\/doi.org\/10.1007\/s00266-006-0081-0","relation":{},"ISSN":["0364-216X","1432-5241"],"issn-type":[{"value":"0364-216X","type":"print"},{"value":"1432-5241","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,31]]}}}