{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T20:48:51Z","timestamp":1793134131900,"version":"4.5.0"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2016,10,3]],"date-time":"2016-10-03T00:00:00Z","timestamp":1475452800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Aesth Plast Surg"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1007\/s00266-016-0703-0","type":"journal-article","created":{"date-parts":[[2016,10,3]],"date-time":"2016-10-03T15:50:03Z","timestamp":1475509803000},"page":"901-907","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":77,"title":["The Use of Integra Dermal Regeneration Template Versus Flaps for Reconstruction of Full-Thickness Scalp Defects Involving the Calvaria: A Cost\u2013Benefit Analysis"],"prefix":"10.1007","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0154-7086","authenticated-orcid":false,"given":"M.","family":"Schiavon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Francescon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Drigo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Salloum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Baraziol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Tesei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Fraccalanza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Barbone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,10,3]]},"reference":[{"issue":"4","key":"703_CR1","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1097\/00000658-198110000-00005","volume":"194","author":"JF Burke","year":"1981","unstructured":"Burke JF, Yannas IV, Quinby WC Jr, Bondoc CC, Jung WK (1981) Successful use of a physiologically acceptable artificial skin in the treatment of extensive burn injury. Ann Surg 194(4):413\u2013428","journal-title":"Ann Surg"},{"issue":"5","key":"703_CR2","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1097\/01.PRS.0000111883.93604.85","volume":"113","author":"JD Frame","year":"2004","unstructured":"Frame JD, Still J, Lakhel-LeCoadou A, Carstens MH, Lorenz C, Orlet H, Spence R, Berger AC, Dantzer E, Burd A (2004) Use of dermal regeneration template in contracture release procedures: a multicenter evaluation. Plast Reconstr Surg 113(5):1330\u20131338","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"703_CR3","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/00006534-200107000-00015","volume":"108","author":"NS Moiemen","year":"2001","unstructured":"Moiemen NS, Staiano JJ, Ojeh NO, Thway Y, Frame JD (2001) Reconstructive surgery with a dermal regeneration template: clinical and histologic study. Plast Reconstr Surg 108(1):93\u2013103","journal-title":"Plast Reconstr Surg"},{"issue":"12","key":"703_CR4","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1016\/j.bjps.2010.02.025","volume":"63","author":"RL Chalmers","year":"2010","unstructured":"Chalmers RL, Smock E, Geh JL (2010) Experience of Integra((R)) in cancer reconstructive surgery. J Plast Reconstr Aesthet Surg 63(12):2081\u20132090","journal-title":"J Plast Reconstr Aesthet Surg"},{"issue":"4S","key":"703_CR5","first-page":"33","volume":"124","author":"ML Iorio","year":"2012","unstructured":"Iorio ML, Goldstein J, Adams M, David H, Steinberg J, Attinger C (2012) Use of Integra, a bilayered human skin equivalent, in the treatment of diabetic foot ulcers. Plast Reconstr Surg 124(4S):33\u201334","journal-title":"Plast Reconstr Surg"},{"issue":"3","key":"703_CR6","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1097\/01.prs.0000270298.68331.8a","volume":"120","author":"AP Tufaro","year":"2007","unstructured":"Tufaro AP, Buck DW, Fischer AC (2007) The use of artificial dermis in the reconstruction of oncologic surgical defects. Plast Reconstr Surg 120(3):638\u2013646","journal-title":"Plast Reconstr Surg"},{"issue":"7","key":"703_CR7","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.jcms.2013.01.009","volume":"41","author":"T Agostini","year":"2013","unstructured":"Agostini T, Dini M, Quattrini LA, Grassetti L, Mori A, Spinelli G, Russo GL, Lazzeri D (2013) A novel combined surgical approach to head and neck dermatofibrosarcoma protuberans. J Craniomaxillofac Surg 41(7):681\u2013685","journal-title":"J Craniomaxillofac Surg"},{"issue":"3","key":"703_CR8","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1097\/PRS.0b013e31820436e3","volume":"127","author":"N Moiemen","year":"2011","unstructured":"Moiemen N, Yarrow J, Hodgson E, Constantinides J, Chipp E, Oakley H, Shale E, Freeth M (2011) Long-term clinical and histological analysis of Integra dermal regeneration template. Plast Reconstr Surg 127(3):1149\u20131154","journal-title":"Plast Reconstr Surg"},{"issue":"11","key":"703_CR9","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1111\/j.1524-4725.2011.02156.x","volume":"37","author":"G Papa","year":"2011","unstructured":"Papa G, Pangos M, Renzi N, Ramella V, Panizzo N, Arnez ZM (2011) Five years of experience using a dermal substitute: indications, histologic studies, and first results using a new single-layer tool. Dermatol Surg 37(11):1631\u20131637","journal-title":"Dermatol Surg"},{"issue":"4","key":"703_CR10","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1097\/01.prs.0000304237.54236.66","volume":"121","author":"LF Lee","year":"2008","unstructured":"Lee LF, Porch JV, Spenler W, Garner WL (2008) Integra in lower extremity reconstruction after burn injury. Plast Reconstr Surg 121(4):1256\u20131262","journal-title":"Plast Reconstr Surg"},{"issue":"7","key":"703_CR11","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.burns.2012.02.017","volume":"38","author":"A Danin","year":"2012","unstructured":"Danin A, Georgesco G, Le TA, Penaud A, Quignon R, Zakine G (2012) Assessment of burned hands reconstructed with Integra((R)) by ultrasonography and elastometry. Burns 38(7):998\u20131004","journal-title":"Burns"},{"issue":"5","key":"703_CR12","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1111\/j.1468-3083.2009.03473.x","volume":"24","author":"J Faulhaber","year":"2010","unstructured":"Faulhaber J, Felcht M, Teerling G, Klemke CD, Wagner C, Goerdt S, Koenen W (2010) Long-term results after reconstruction of full thickness scalp defects with a dermal regeneration template. J Eur Acad Dermatol Venereol 24(5):572\u2013577","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"5","key":"703_CR13","doi-asserted-by":"crossref","first-page":"259","DOI":"10.2310\/7750.2011.10050","volume":"15","author":"M Felcht","year":"2011","unstructured":"Felcht M, Koenen W, Sassmann G, Goerdt S, Faulhaber J (2011) Two-stage reconstruction of head and neck defects after tumor resection with a dermal regeneration template. J Cutan Med Surg 15(5):259\u2013265","journal-title":"J Cutan Med Surg"},{"issue":"5","key":"703_CR14","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1097\/00004630-200209000-00002","volume":"23","author":"CM Ryan","year":"2002","unstructured":"Ryan CM, Schoenfeld DA, Malloy M, Schulz JT III, Sheridan RL, Tompkins RG (2002) Use of Integra artificial skin is associated with decreased length of stay for severely injured adult burn survivors. J Burn Care Rehabil 23(5):311\u2013317","journal-title":"J Burn Care Rehabil"},{"issue":"1","key":"703_CR15","first-page":"1","volume":"18","author":"DW Voigt","year":"2006","unstructured":"Voigt DW, Paul CN, Edwards P, Metz P (2006) Economic study of collagen-glycosaminoglycan biodegradable matrix for chronic wounds. Wounds 18(1):1\u20137","journal-title":"Wounds"},{"issue":"3","key":"703_CR16","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1097\/SCS.0b013e3181d8418e","volume":"21","author":"MA Khan","year":"2010","unstructured":"Khan MA, Ali SN, Farid M, Pancholi M, Rayatt S, Yap LH (2010) Use of dermal regeneration template (Integra) for reconstruction of full-thickness complex oncologic scalp defects. J Craniofac Surg 21(3):905\u2013909","journal-title":"J Craniofac Surg"},{"issue":"4","key":"703_CR17","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1097\/01.PRS.0000154210.60284.C6","volume":"115","author":"E Komorowska-Timek","year":"2005","unstructured":"Komorowska-Timek E, Gabriel A, Bennett DC, Miles D, Garberoglio C, Cheng C, Gupta S (2005) Artificial dermis as an alternative for coverage of complex scalp defects following excision of malignant tumors. Plast Reconstr Surg 115(4):1010\u20131017","journal-title":"Plast Reconstr Surg"},{"issue":"11","key":"703_CR18","first-page":"890","volume":"8","author":"O Inhoff","year":"2010","unstructured":"Inhoff O, Faulhaber J, Rothhaar B, Goerdt S, Koenen W (2010) Analysis of treatment costs for complex scalp wounds. J Dtsch Dermatol Ges 8(11):890\u2013896","journal-title":"J Dtsch Dermatol Ges"},{"issue":"2","key":"703_CR19","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1055\/s-0031-1289167","volume":"28","author":"ZK Menn","year":"2012","unstructured":"Menn ZK, Lee E, Klebuc MJ (2012) Acellular dermal matrix and negative pressure wound therapy: a tissue-engineered alternative to free tissue transfer in the compromised host. J Reconstr Microsurg 28(2):139\u2013144","journal-title":"J Reconstr Microsurg"}],"container-title":["Aesthetic Plastic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00266-016-0703-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00266-016-0703-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00266-016-0703-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T20:16:12Z","timestamp":1498335372000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00266-016-0703-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,3]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["703"],"URL":"https:\/\/doi.org\/10.1007\/s00266-016-0703-0","relation":{},"ISSN":["0364-216X","1432-5241"],"issn-type":[{"value":"0364-216X","type":"print"},{"value":"1432-5241","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,3]]}}}