{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T17:01:16Z","timestamp":1793293276987,"version":"4.5.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T00:00:00Z","timestamp":1571616000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T00:00:00Z","timestamp":1571616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100014718","name":"Innovative Research Group Project of the National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81273169"],"award-info":[{"award-number":["81273169"]}],"id":[{"id":"10.13039\/100014718","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Aesth Plast Surg"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1007\/s00266-019-01518-y","type":"journal-article","created":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T04:30:17Z","timestamp":1571805017000},"page":"207-218","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Comparative Efficacy and Safety of Common Therapies in Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis"],"prefix":"10.1007","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2609-0572","authenticated-orcid":false,"given":"Yawei","family":"Bao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanshan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhipeng","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jixiang","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faming","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,10,21]]},"reference":[{"key":"1518_CR1","doi-asserted-by":"publisher","first-page":"e25","DOI":"10.1097\/GOX.0b013e31829c4597","volume":"1","author":"C Huang","year":"2013","unstructured":"Huang C, Murphy GF, Akaishi S et al (2013) Keloids and hypertrophic scars: update and future directions. Plast Reconstr Surg Glob Open 1:e25. \nhttps:\/\/doi.org\/10.1097\/GOX.0b013e31829c4597","journal-title":"Plast Reconstr Surg Glob Open"},{"key":"1518_CR2","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1097\/01.mop.0000236389.41462.ef","volume":"18","author":"AE Slemp","year":"2006","unstructured":"Slemp AE, Kirschner RE (2006) Keloids and scars: a review of keloids and scars, their pathogenesis, risk factors, and management. Curr Opin Pediatr 18:396\u2013402. \nhttps:\/\/doi.org\/10.1097\/01.mop.0000236389.41462.ef","journal-title":"Curr Opin Pediatr"},{"issue":"Suppl 1","key":"1518_CR3","doi-asserted-by":"publisher","first-page":"s2","DOI":"10.1111\/j.1524-475X.2011.00707.x","volume":"19","author":"R Ogawa","year":"2011","unstructured":"Ogawa R (2011) Mechanobiology of scarring. Wound Repair Regen 19(Suppl 1):s2\u2013s9. \nhttps:\/\/doi.org\/10.1111\/j.1524-475X.2011.00707.x","journal-title":"Wound Repair Regen"},{"key":"1518_CR4","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1007\/s00106-006-1462-z","volume":"54","author":"A Baisch","year":"2006","unstructured":"Baisch A, Riedel F (2006) Hyperplastic scars and keloids. Part I: basics and prevention. HNO 54:893\u2013905. \nhttps:\/\/doi.org\/10.1007\/s00106-006-1462-z","journal-title":"HNO"},{"key":"1518_CR5","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1097\/00000637-199408000-00005","volume":"33","author":"S Younai","year":"1994","unstructured":"Younai S, Nichter LS, Wellisz T et al (1994) Modulation of collagen synthesis by transforming growth factor-beta in keloid and hypertrophic scar fibroblasts. Ann Plast Surg 33:148\u2013151","journal-title":"Ann Plast Surg"},{"key":"1518_CR6","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.clindermatol.2006.09.009","volume":"25","author":"DT Robles","year":"2007","unstructured":"Robles DT, Berg D (2007) Abnormal wound healing: keloids. Clin Dermatol 25:26\u201332. \nhttps:\/\/doi.org\/10.1016\/j.clindermatol.2006.09.009","journal-title":"Clin Dermatol"},{"key":"1518_CR7","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1183\/09031936.00027607","volume":"30","author":"C Garcia-Vidal","year":"2007","unstructured":"Garcia-Vidal C, Calbo E, Pascual V et al (2007) Effects of systemic steroids in patients with severe community-acquired pneumonia. Eur Respir J 30:951\u2013956. \nhttps:\/\/doi.org\/10.1183\/09031936.00027607","journal-title":"Eur Respir J"},{"key":"1518_CR8","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1080\/02844310500430003","volume":"40","author":"G Muneuchi","year":"2006","unstructured":"Muneuchi G, Suzuki S, Onodera M et al (2006) Long-term outcome of intralesional injection of triamcinolone acetonide for the treatment of keloid scars in Asian patients. Scand J Plast Reconstr Surg Hand Surg 40:111\u2013116. \nhttps:\/\/doi.org\/10.1080\/02844310500430003","journal-title":"Scand J Plast Reconstr Surg Hand Surg"},{"key":"1518_CR9","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1007\/s00266-008-9152-8","volume":"32","author":"B Hochman","year":"2008","unstructured":"Hochman B, Locali RF, Matsuoka PK et al (2008) Intralesional triamcinolone acetonide for keloid treatment: a systematic review. Aesthetic Plast Surg 32:705\u2013709. \nhttps:\/\/doi.org\/10.1007\/s00266-008-9152-8","journal-title":"Aesthetic Plast Surg"},{"key":"1518_CR10","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1097\/00006534-200208000-00031","volume":"110","author":"TA Mustoe","year":"2002","unstructured":"Mustoe TA, Cooter RD, Gold MH et al (2002) International clinical recommendations on scar management. Plast Reconstr Surg 110:560\u2013571","journal-title":"Plast Reconstr Surg"},{"key":"1518_CR11","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1111\/j.1524-4725.2006.32195.x","volume":"32","author":"A Asilian","year":"2006","unstructured":"Asilian A, Darougheh A, Shariati F (2006) New combination of triamcinolone, 5-fluorouracil, and pulsed-dye laser for treatment of keloid and hypertrophic scars. Dermatol Surg 32:907\u2013915. \nhttps:\/\/doi.org\/10.1111\/j.1524-4725.2006.32195.x","journal-title":"Dermatol Surg"},{"key":"1518_CR12","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1111\/j.1365-2230.2007.02631.x","volume":"34","author":"A Darougheh","year":"2009","unstructured":"Darougheh A, Asilian A, Shariati F (2009) Intralesional triamcinolone alone or in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars. Clin Exp Dermatol 34:219\u2013223. \nhttps:\/\/doi.org\/10.1111\/j.1365-2230.2007.02631.x","journal-title":"Clin Exp Dermatol"},{"key":"1518_CR13","first-page":"1003","volume":"64","author":"MA Khan","year":"2014","unstructured":"Khan MA, Bashir MM, Khan FA (2014) Intralesional triamcinolone alone and in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars. J Pak Med Assoc 64:1003\u20131007","journal-title":"J Pak Med Assoc"},{"key":"1518_CR14","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1007\/s11136-011-9924-5","volume":"21","author":"MB van der Wal","year":"2012","unstructured":"van der Wal MB, Tuinebreijer WE, Bloemen MC et al (2012) Rasch analysis of the Patient and Observer Scar Assessment Scale (POSAS) in burn scars. Qual Life Res 21:13\u201323. \nhttps:\/\/doi.org\/10.1007\/s11136-011-9924-5","journal-title":"Qual Life Res"},{"key":"1518_CR15","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1001\/archderm.138.9.1149","volume":"138","author":"W Manuskiatti","year":"2002","unstructured":"Manuskiatti W, Fitzpatrick RE (2002) Treatment response of keloidal and hypertrophic sternotomy scars: comparison among intralesional corticosteroid, 5-fluorouracil, and 585-nm flashlamp-pumped pulsed-dye laser treatments. Arch Dermatol 138:1149\u20131155","journal-title":"Arch Dermatol"},{"key":"1518_CR16","doi-asserted-by":"publisher","first-page":"251","DOI":"10.3109\/09546639909056040","volume":"10","author":"E Tan","year":"1999","unstructured":"Tan E, Chua S, Lim J (1999) Topical silicone gel sheet versus intralesional injections of triamcinolone acetonide in the treatment of keloids\u2014a patient-controlled comparative clinical trial. J Dermatol Treat 10:251\u2013254","journal-title":"J Dermatol Treat"},{"key":"1518_CR17","doi-asserted-by":"publisher","first-page":"343","DOI":"10.4103\/0378-6323.42899","volume":"74","author":"FX Margaret Shanthi","year":"2008","unstructured":"Margaret Shanthi FX, Ernest K, Dhanraj P (2008) Comparison of intralesional verapamil with intralesional triamcinolone in the treatment of hypertrophic scars and keloids. Indian J Dermatol Venereol Leprol 74:343\u2013348","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"1518_CR18","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1111\/j.1524-4725.2011.02137.x","volume":"38","author":"A Sadeghinia","year":"2012","unstructured":"Sadeghinia A, Sadeghinia S (2012) Comparison of the efficacy of intralesional triamcinolone acetonide and 5-fluorouracil tattooing for the treatment of keloids. Dermatol Surg 38:104\u2013109. \nhttps:\/\/doi.org\/10.1111\/j.1524-4725.2011.02137.x","journal-title":"Dermatol Surg"},{"key":"1518_CR19","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1007\/s12262-011-0399-y","volume":"74","author":"AK Saha","year":"2012","unstructured":"Saha AK, Mukhopadhyay M (2012) A comparative clinical study on role of 5-flurouracil versus triamcinolone in the treatment of keloids. Indian J Surg 74:326\u2013329. \nhttps:\/\/doi.org\/10.1007\/s12262-011-0399-y","journal-title":"Indian J Surg"},{"key":"1518_CR20","first-page":"1256","volume":"12","author":"A Rossi","year":"2013","unstructured":"Rossi A, Lu R, Frey MK et al (2013) The use of the 300 microsecond 1064\u00a0nm Nd:YAG laser in the treatment of keloids. J Drugs Dermatol 12:1256\u20131262","journal-title":"J Drugs Dermatol"},{"key":"1518_CR21","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/j.burns.2013.09.029","volume":"40","author":"RB Ahuja","year":"2014","unstructured":"Ahuja RB, Chatterjee P (2014) Comparative efficacy of intralesional verapamil hydrochloride and triamcinolone acetonide in hypertrophic scars and keloids. Burns 40:583\u2013588. \nhttps:\/\/doi.org\/10.1016\/j.burns.2013.09.029","journal-title":"Burns"},{"key":"1518_CR22","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1111\/jocd.12132","volume":"14","author":"K Payapvipapong","year":"2015","unstructured":"Payapvipapong K, Niumpradit N, Piriyanand C et al (2015) The treatment of keloids and hypertrophic scars with intralesional bleomycin in skin of color. J Cosmet Dermatol 14:83\u201390. \nhttps:\/\/doi.org\/10.1111\/jocd.12132","journal-title":"J Cosmet Dermatol"},{"key":"1518_CR23","doi-asserted-by":"publisher","first-page":"774","DOI":"10.2340\/00015555-2384","volume":"96","author":"PL Danielsen","year":"2016","unstructured":"Danielsen PL, Rea SM, Wood FM et al (2016) Verapamil is less effective than triamcinolone for prevention of keloid scar recurrence after excision in a randomized controlled trial. Acta Derm Venereol 96:774\u2013778. \nhttps:\/\/doi.org\/10.2340\/00015555-2384","journal-title":"Acta Derm Venereol"},{"key":"1518_CR24","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.phrp.2016.08.005","volume":"7","author":"SS Meymandi","year":"2016","unstructured":"Meymandi SS, Moosazadeh M, Rezazadeh A (2016) Comparing two methods of cryotherapy and intense pulsed light with triamcinolone injection in the treatment of keloid and hypertrophic scars: a clinical trial. Osong Public Health Res Perspect 7:313\u2013319. \nhttps:\/\/doi.org\/10.1016\/j.phrp.2016.08.005","journal-title":"Osong Public Health Res Perspect"},{"key":"1518_CR25","doi-asserted-by":"publisher","first-page":"3607","DOI":"10.3892\/etm.2017.4438","volume":"13","author":"XE Chen","year":"2017","unstructured":"Chen XE, Liu J, Bin Jameel AA et al (2017) Combined effects of long-pulsed neodymium-yttrium-aluminum-garnet laser, diprospan and 5-fluorouracil in the treatment of keloid scars. Exp Ther Med 13:3607\u20133612. \nhttps:\/\/doi.org\/10.3892\/etm.2017.4438","journal-title":"Exp Ther Med"},{"key":"1518_CR26","doi-asserted-by":"publisher","first-page":"1482","DOI":"10.1016\/j.burns.2018.05.005","volume":"44","author":"R Abedini","year":"2018","unstructured":"Abedini R, Sasani P, Mahmoudi HR et al (2018) Comparison of intralesional verapamil versus intralesional corticosteroids in treatment of keloids and hypertrophic scars: a randomized controlled trial. Burns 44:1482\u20131488. \nhttps:\/\/doi.org\/10.1016\/j.burns.2018.05.005","journal-title":"Burns"},{"key":"1518_CR27","first-page":"212","volume":"7","author":"S Srivastava","year":"2018","unstructured":"Srivastava S, Patil A, Prakash C et al (2018) Comparison of intralesional triamcinolone acetonide, 5-fluorouracil, and their combination in treatment of keloids. World J Plast Surg 7:212\u2013219","journal-title":"World J Plast Surg"},{"key":"1518_CR28","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.12887","author":"S Alexander","year":"2019","unstructured":"Alexander S, Girisha BS, Sripathi H et al (2019) Efficacy of fractional CO2 laser with intralesional steroid compared with intralesional steroid alone in the treatment of keloids and hypertrophic scars. J Cosmet Dermatol. \nhttps:\/\/doi.org\/10.1111\/jocd.12887","journal-title":"J Cosmet Dermatol"},{"key":"1518_CR29","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.bjps.2018.05.052","volume":"72","author":"KE Hietanen","year":"2019","unstructured":"Hietanen KE, Jarvinen TA, Huhtala H et al (2019) Treatment of keloid scars with intralesional triamcinolone and 5-fluorouracil injections\u2014a randomized controlled trial. J Plast Reconstr Aesthet Surg 72:4\u201311. \nhttps:\/\/doi.org\/10.1016\/j.bjps.2018.05.052","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"1518_CR30","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.burns.2018.08.011","volume":"45","author":"FA Khalid","year":"2019","unstructured":"Khalid FA, Mehrose MY, Saleem M et al (2019) Comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: randomised control trial. Burns 45:69\u201375. \nhttps:\/\/doi.org\/10.1016\/j.burns.2018.08.011","journal-title":"Burns"},{"key":"1518_CR31","doi-asserted-by":"publisher","first-page":"4","DOI":"10.5826\/dpc.0901a02","volume":"9","author":"N Saki","year":"2019","unstructured":"Saki N, Mokhtari R, Nozari F (2019) Comparing the efficacy of intralesional triamcinolone acetonide with verapamil in treatment of keloids: a randomized controlled trial. Dermatol Pract Concept 9:4\u20139. \nhttps:\/\/doi.org\/10.5826\/dpc.0901a02","journal-title":"Dermatol Pract Concept"},{"key":"1518_CR32","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1089\/wound.2018.0798","volume":"8","author":"S Srivastava","year":"2019","unstructured":"Srivastava S, Kumari H, Singh A (2019) Comparison of fractional CO2 laser, verapamil, and triamcinolone for the treatment of keloid. Adv Wound Care (New Rochelle) 8:7\u201313. \nhttps:\/\/doi.org\/10.1089\/wound.2018.0798","journal-title":"Adv Wound Care (New Rochelle)"},{"key":"1518_CR33","doi-asserted-by":"publisher","first-page":"173","DOI":"10.2147\/ccid.s191137","volume":"12","author":"AA Tawfik","year":"2019","unstructured":"Tawfik AA, Fathy M, Badawi A et al (2019) Topical 5 fluorouracil cream vs combined 5 fluorouracil and fractional erbium YAG laser for treatment of severe hypertrophic scars. Clin Cosmet Investig Dermatol 12:173\u2013180. \nhttps:\/\/doi.org\/10.2147\/ccid.s191137","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"1518_CR34","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1111\/iwj.12629","volume":"14","author":"Y Ren","year":"2017","unstructured":"Ren Y, Zhou X, Wei Z et al (2017) Efficacy and safety of triamcinolone acetonide alone and in combination with 5-fluorouracil for treating hypertrophic scars and keloids: a systematic review and meta-analysis. Int Wound J 14:480\u2013487. \nhttps:\/\/doi.org\/10.1111\/iwj.12629","journal-title":"Int Wound J"},{"key":"1518_CR35","doi-asserted-by":"publisher","first-page":"1635","DOI":"10.2147\/tcrm.s118748","volume":"12","author":"Z Li","year":"2016","unstructured":"Li Z, Jin Z (2016) Comparative effect and safety of verapamil in keloid and hypertrophic scar treatment: a meta-analysis. Ther Clin Risk Manag 12:1635\u20131641. \nhttps:\/\/doi.org\/10.2147\/tcrm.s118748","journal-title":"Ther Clin Risk Manag"},{"key":"1518_CR36","doi-asserted-by":"publisher","first-page":"973","DOI":"10.2147\/tcrm.s162315","volume":"14","author":"Z Zhang","year":"2018","unstructured":"Zhang Z, Cheng L, Wang R et al (2018) Effects and safety of triamcinolone acetonide-controlled common therapy in keloid treatment: a Bayesian network meta-analysis. Ther Clin Risk Manag 14:973\u2013980. \nhttps:\/\/doi.org\/10.2147\/tcrm.s162315","journal-title":"Ther Clin Risk Manag"},{"key":"1518_CR37","doi-asserted-by":"publisher","first-page":"e12326","DOI":"10.1111\/cpr.12326","volume":"50","author":"Y He","year":"2017","unstructured":"He Y, Deng Z, Alghamdi M et al (2017) From genetics to epigenetics: new insights into keloid scarring. Cell Prolif 50:e12326. \nhttps:\/\/doi.org\/10.1111\/cpr.12326","journal-title":"Cell Prolif"},{"key":"1518_CR38","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1007\/s00403-009-1014-y","volume":"302","author":"B Shih","year":"2010","unstructured":"Shih B, Bayat A (2010) Genetics of keloid scarring. Arch Dermatol Res 302:319\u2013339. \nhttps:\/\/doi.org\/10.1007\/s00403-009-1014-y","journal-title":"Arch Dermatol Res"},{"key":"1518_CR39","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1016\/j.burns.2014.02.011","volume":"40","author":"AI Arno","year":"2014","unstructured":"Arno AI, Gauglitz GG, Barret JP et al (2014) Up-to-date approach to manage keloids and hypertrophic scars: a useful guide. Burns 40:1255\u20131266. \nhttps:\/\/doi.org\/10.1016\/j.burns.2014.02.011","journal-title":"Burns"},{"key":"1518_CR40","doi-asserted-by":"publisher","first-page":"113","DOI":"10.2119\/molmed.2009.00153","volume":"17","author":"GG Gauglitz","year":"2011","unstructured":"Gauglitz GG, Korting HC, Pavicic T et al (2011) Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies. Mol Med 17:113\u2013125. \nhttps:\/\/doi.org\/10.2119\/molmed.2009.00153","journal-title":"Mol Med"},{"key":"1518_CR41","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1517\/13543776.2015.1056736","volume":"25","author":"E Carrillo","year":"2015","unstructured":"Carrillo E, Navarro SA, Ramirez A et al (2015) 5-Fluorouracil derivatives: a patent review (2012\u20132014). Expert Opin Ther Pat 25:1131\u20131144. \nhttps:\/\/doi.org\/10.1517\/13543776.2015.1056736","journal-title":"Expert Opin Ther Pat"},{"key":"1518_CR42","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1001\/archsurg.1994.01420250119015","volume":"129","author":"RC Lee","year":"1994","unstructured":"Lee RC, Doong H, Jellema AF (1994) The response of burn scars to intralesional verapamil. Report of five cases. Arch Surg 129:107\u2013111","journal-title":"Arch Surg"},{"key":"1518_CR43","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1097\/prs.0000000000005323","volume":"143","author":"A Fanous","year":"2019","unstructured":"Fanous A, Bezdjian A, Caglar D et al (2019) Treatment of keloid scars with botulinum toxin type A versus triamcinolone in an athymic nude mouse model. Plast Reconstr Surg 143:760\u2013767. \nhttps:\/\/doi.org\/10.1097\/prs.0000000000005323","journal-title":"Plast Reconstr Surg"},{"key":"1518_CR44","doi-asserted-by":"publisher","first-page":"43e","DOI":"10.1097\/prs.0000000000003426","volume":"140","author":"HC Chen","year":"2017","unstructured":"Chen HC, Yen CI, Yang SY et al (2017) Comparison of steroid and botulinum toxin type A monotherapy with combination therapy for treating human hypertrophic scars in an animal model. Plast Reconstr Surg 140:43e\u201349e. \nhttps:\/\/doi.org\/10.1097\/prs.0000000000003426","journal-title":"Plast Reconstr Surg"}],"container-title":["Aesthetic Plastic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00266-019-01518-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00266-019-01518-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00266-019-01518-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,19]],"date-time":"2020-10-19T23:21:20Z","timestamp":1603149680000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00266-019-01518-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,21]]},"references-count":44,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["1518"],"URL":"https:\/\/doi.org\/10.1007\/s00266-019-01518-y","relation":{},"ISSN":["0364-216X","1432-5241"],"issn-type":[{"value":"0364-216X","type":"print"},{"value":"1432-5241","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,21]]},"assertion":[{"value":"15 August 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 October 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 October 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"All authors state that there is no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"For this type of study, informed consent is not required.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Statement of Human and Animal Rights, or Ethical Approval"}}]}}