{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T23:40:53Z","timestamp":1785800453868,"version":"3.56.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2020,1,22]],"date-time":"2020-01-22T00:00:00Z","timestamp":1579651200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,1,22]],"date-time":"2020-01-22T00:00:00Z","timestamp":1579651200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Aesth Plast Surg"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1007\/s00266-020-01616-2","type":"journal-article","created":{"date-parts":[[2020,1,22]],"date-time":"2020-01-22T21:03:43Z","timestamp":1579727023000},"page":"664-672","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Skin-Reducing Mastectomy and Pre-pectoral Breast Reconstruction in Large Ptotic Breasts"],"prefix":"10.1007","volume":"44","author":[{"given":"Michele","family":"Maruccia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6094-5159","authenticated-orcid":false,"given":"Rossella","family":"Elia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Gurrado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Moschetta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora","family":"Nacchiero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Bolletta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Testini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Giudice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,1,22]]},"reference":[{"issue":"1","key":"1616_CR1","doi-asserted-by":"publisher","first-page":"53","DOI":"10.21037\/gs.2018.10.08","volume":"8","author":"G Jones","year":"2019","unstructured":"Jones G, Antony AK (2019) Single stage, direct to implant pre-pectoral breast reconstruction. Gland Surg 8(1):53\u201360. https:\/\/doi.org\/10.21037\/gs.2018.10.08","journal-title":"Gland Surg"},{"issue":"6","key":"1616_CR2","doi-asserted-by":"publisher","first-page":"1540","DOI":"10.1097\/PRS.0000000000001277","volume":"135","author":"DC Hammond","year":"2015","unstructured":"Hammond DC, Schmitt WP, O\u2019Connor EA (2015) Treatment of breast animation deformity in implant-based reconstruction with pocket change to the subcutaneous position. Plast Reconstr Surg 135(6):1540\u20131544. https:\/\/doi.org\/10.1097\/PRS.0000000000001277","journal-title":"Plast Reconstr Surg"},{"issue":"5","key":"1616_CR3","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1093\/asj\/sjx261","volume":"38","author":"A Gabriel","year":"2018","unstructured":"Gabriel A, Sigalove S, Sigalove NM et al (2018) Prepectoral revision breast reconstruction for treatment of implant-associated animation deformity: a review of 102 reconstructions. Aesthet Surg J 38(5):519\u2013526. https:\/\/doi.org\/10.1093\/asj\/sjx261","journal-title":"Aesthet Surg J"},{"issue":"5S","key":"1616_CR4","doi-asserted-by":"publisher","first-page":"51S","DOI":"10.1097\/PRS.0000000000003942","volume":"140","author":"RP Ter Louw","year":"2017","unstructured":"Ter Louw RP, Nahabedian MY (2017) Prepectoral breast reconstruction. Plast Reconstr Surg 140(5S):51S. https:\/\/doi.org\/10.1097\/PRS.0000000000003942","journal-title":"Plast Reconstr Surg"},{"issue":"6","key":"1616_CR5","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1111\/ans.12849","volume":"87","author":"G Berna","year":"2017","unstructured":"Berna G, Cawthorn SJ, Papaccio G, Balestrieri N (2017) Evaluation of a novel breast reconstruction technique using the Braxon\u00ae acellular dermal matrix: a new muscle-sparing breast reconstruction. ANZ J Surg 87(6):493\u2013498. https:\/\/doi.org\/10.1111\/ans.12849","journal-title":"ANZ J Surg"},{"issue":"6","key":"1616_CR6","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1111\/tbj.12810","volume":"23","author":"R Vidya","year":"2017","unstructured":"Vidya R, Masi\u00e0 J, Cawthorn S et al (2017) Evaluation of the effectiveness of the prepectoral breast reconstruction with Braxon dermal matrix: first multicenter European report on 100 cases. Breast J 23(6):670\u2013676. https:\/\/doi.org\/10.1111\/tbj.12810","journal-title":"Breast J"},{"issue":"4","key":"1616_CR7","doi-asserted-by":"publisher","first-page":"e703","DOI":"10.1016\/j.clbc.2017.11.015","volume":"18","author":"L Cattelani","year":"2018","unstructured":"Cattelani L, Polotto S, Arcuri MF, Pedrazzi G, Linguadoca C, Bonati E (2018) One-step prepectoral breast reconstruction with dermal matrix-covered implant compared to submuscular implantation: functional and cost evaluation. Clin Breast Cancer 18(4):e703\u2013e711. https:\/\/doi.org\/10.1016\/j.clbc.2017.11.015","journal-title":"Clin Breast Cancer"},{"issue":"1","key":"1616_CR8","doi-asserted-by":"publisher","first-page":"11","DOI":"10.21037\/gs.2018.08.01","volume":"8","author":"AA Salibian","year":"2019","unstructured":"Salibian AA, Frey JD, Karp NS (2019) Strategies and considerations in selecting between subpectoral and prepectoral breast reconstruction. Gland Surg 8(1):11\u201318. https:\/\/doi.org\/10.21037\/gs.2018.08.01","journal-title":"Gland Surg"},{"key":"1616_CR9","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.jpra.2017.11.003","volume":"15","author":"G Giudice","year":"2018","unstructured":"Giudice G, Maruccia M, Nacchiero E, Elia R, Annoscia P, Vestita M (2018) Dual plane breast implant reconstruction in large sized breasts: how to maximise the result following first stage total submuscular expansion. JPRAS Open 15:74\u201380. https:\/\/doi.org\/10.1016\/j.jpra.2017.11.003","journal-title":"JPRAS Open"},{"issue":"3","key":"1616_CR10","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1097\/01.prs.0000233024.08392.14","volume":"118","author":"MB Nava","year":"2006","unstructured":"Nava MB, Cortinovis U, Ottolenghi J et al (2006) Skin-reducing mastectomy. Plast Reconstr Surg 118(3):603\u2013610. https:\/\/doi.org\/10.1097\/01.prs.0000233024.08392.14(discussion 611-613)","journal-title":"Plast Reconstr Surg"},{"issue":"6","key":"1616_CR11","doi-asserted-by":"publisher","first-page":"1702","DOI":"10.1097\/PRS.0000000000002227","volume":"137","author":"GG Caputo","year":"2016","unstructured":"Caputo GG, Marchetti A, Dalla Pozza E et al (2016) Skin-reduction breast reconstructions with prepectoral implant. Plast Reconstr Surg 137(6):1702\u20131705. https:\/\/doi.org\/10.1097\/PRS.0000000000002227","journal-title":"Plast Reconstr Surg"},{"issue":"6S Suppl 5","key":"1616_CR12","doi-asserted-by":"publisher","first-page":"S404","DOI":"10.1097\/sap.0000000000001791","volume":"82","author":"J Thuman","year":"2019","unstructured":"Thuman J, Freitas AM, Schaeffer C, Campbell CA (2019) Prepectoral wise-pattern staged implant-based breast reconstruction for obese or ptotic patients. Ann Plast Surg 82(6S Suppl 5):S404\u2013S409. https:\/\/doi.org\/10.1097\/sap.0000000000001791","journal-title":"Ann Plast Surg"},{"issue":"10","key":"1616_CR13","doi-asserted-by":"publisher","first-page":"e296","DOI":"10.1371\/journal.pmed.0040296","volume":"4","author":"E von Elm","year":"2007","unstructured":"von Elm E, Altman DG, Egger M, Pocock SJ, G\u00f8tzsche PC, Vandenbroucke JP (2007) The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. PLoS Med. 4(10):e296. https:\/\/doi.org\/10.1371\/journal.pmed.0040296","journal-title":"PLoS Med."},{"issue":"2","key":"1616_CR14","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1097\/01.sla.0000133083.54934.ae","volume":"240","author":"D Dindo","year":"2004","unstructured":"Dindo D, Demartines N, Clavien P-A (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240(2):205\u2013213","journal-title":"Ann Surg"},{"key":"1616_CR15","unstructured":"Surgical Site Infection (SSI) Event (2016) Centers for disease control and prevention. https:\/\/www.cdc.gov\/nhsn\/pdfs\/pscmanual\/9pscssicurrent.pdf. Accessed 1 Nov 2019"},{"issue":"2","key":"1616_CR16","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1097\/PRS.0b013e3181aee807","volume":"124","author":"AL Pusic","year":"2009","unstructured":"Pusic AL, Klassen AF, Scott AM, Klok JA, Cordeiro PG, Cano SJ (2009) Development of a new patient-reported outcome measure for breast surgery: the BREAST-Q. Plast Reconstr Surg 124(2):345\u2013353. https:\/\/doi.org\/10.1097\/PRS.0b013e3181aee807","journal-title":"Plast Reconstr Surg"},{"issue":"4","key":"1616_CR17","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1111\/tbj.13291","volume":"25","author":"G Giudice","year":"2019","unstructured":"Giudice G, Maruccia M, Vestita M et al (2019) The medial-central septum based mammaplasty: a reliable technique to preserve nipple-areola complex sensitivity in post bariatric patients. Breast J 25(4):590\u2013596. https:\/\/doi.org\/10.1111\/tbj.13291","journal-title":"Breast J"},{"key":"1616_CR18","doi-asserted-by":"publisher","first-page":"1434","DOI":"10.1007\/s00266-018-1126-x","volume":"42","author":"V Bucaria","year":"2018","unstructured":"Bucaria V, Elia R, Maruccia M, Vestita M, Boccuzzi A, Giudice G (2018) Methylene blue: a color test for a quality de-epithelialization. Aesthetic Plast Surg 42:1434\u20131435. https:\/\/doi.org\/10.1007\/s00266-018-1126-x","journal-title":"Aesthetic Plast Surg"},{"issue":"5","key":"1616_CR19","doi-asserted-by":"publisher","first-page":"1058","DOI":"10.1007\/s00266-017-0899-7","volume":"41","author":"A Inbal","year":"2017","unstructured":"Inbal A, Gur E, Lemelman BT et al (2017) Optimizing patient selection for direct-to-implant immediate breast reconstruction using wise-pattern skin-reducing mastectomy in large and ptotic breasts. Aesthetic Plast Surg 41(5):1058\u20131067. https:\/\/doi.org\/10.1007\/s00266-017-0899-7","journal-title":"Aesthetic Plast Surg"},{"issue":"1","key":"1616_CR20","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1097\/00006534-200207000-00035","volume":"110","author":"DC Hammond","year":"2002","unstructured":"Hammond DC, Capraro PA, Ozolins EB, Arnold JF (2002) Use of a skin-sparing reduction pattern to create a combination skin-muscle flap pocket in immediate breast reconstruction. Plast Reconstr Surg 110(1):206\u2013211. https:\/\/doi.org\/10.1097\/00006534-200207000-00035","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"1616_CR21","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1097\/PRS.0b013e3182547d42","volume":"130","author":"M Salgarello","year":"2012","unstructured":"Salgarello M, Visconti G, Barone-Adesi L et al (2012) Inverted-T skin-reducing mastectomy with immediate implant reconstruction using the submuscular-subfascial pocket. Plast Reconstr Surg 130(1):31\u201341. https:\/\/doi.org\/10.1097\/PRS.0b013e3182547d42","journal-title":"Plast Reconstr Surg"},{"issue":"5","key":"1616_CR22","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1097\/00000658-199705000-00013","volume":"225","author":"GW Carlson","year":"1997","unstructured":"Carlson GW, Bostwick J, Styblo TM et al (1997) Skin-sparing mastectomy. Oncologic and reconstructive considerations. Ann Surg 225(5):570\u2013575. https:\/\/doi.org\/10.1097\/00000658-199705000-00013(discussion 575\u2013578)","journal-title":"Ann Surg"},{"issue":"5","key":"1616_CR23","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.1097\/prs.0000000000005519","volume":"143","author":"AK Antony","year":"2019","unstructured":"Antony AK, Robinson EC (2019) An algorithmic approach to prepectoral direct-to-implant breast reconstruction: version 2.0. Plast Reconstr Surg 143(5):1311\u20131319. https:\/\/doi.org\/10.1097\/prs.0000000000005519","journal-title":"Plast Reconstr Surg"},{"issue":"5","key":"1616_CR24","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1097\/PRS.0000000000004270","volume":"141","author":"BG Baker","year":"2018","unstructured":"Baker BG, Irri R, MacCallum V, Chattopadhyay R, Murphy J, Harvey JR (2018) A prospective comparison of short-term outcomes of subpectoral and prepectoral strattice-based immediate breast reconstruction. Plast Reconstr Surg 141(5):1077\u20131084. https:\/\/doi.org\/10.1097\/PRS.0000000000004270","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"1616_CR25","doi-asserted-by":"publisher","first-page":"236e","DOI":"10.1097\/PRS.0000000000005135","volume":"143","author":"R Vidya","year":"2019","unstructured":"Vidya R, Green M (2019) Minimal pain with prepectoral implant-based breast reconstruction. Plast Reconstr Surg 143(1):236e. https:\/\/doi.org\/10.1097\/PRS.0000000000005135","journal-title":"Plast Reconstr Surg"},{"issue":"24","key":"1616_CR26","first-page":"5058","volume":"20","author":"M Maruccia","year":"2016","unstructured":"Maruccia M, Mazzocchi M, Dessy LA, Onesti MG (2016) One-stage breast reconstruction techniques in elderly patients to preserve quality of life. Eur Rev Med Pharmacol Sci 20(24):5058\u20135066","journal-title":"Eur Rev Med Pharmacol Sci"},{"issue":"2","key":"1616_CR27","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1111\/tbj.12860","volume":"24","author":"M Maruccia","year":"2018","unstructured":"Maruccia M, Di Taranto G, Onesti MG (2018) One-stage muscle-sparing breast reconstruction in elderly patients: a new tool for retaining excellent quality of life. Breast J 24(2):180\u2013183. https:\/\/doi.org\/10.1111\/tbj.12860","journal-title":"Breast J"},{"issue":"11","key":"1616_CR28","doi-asserted-by":"publisher","first-page":"1527","DOI":"10.1016\/j.bjps.2017.06.023","volume":"70","author":"MG Onesti","year":"2017","unstructured":"Onesti MG, Maruccia M, Di Taranto G et al (2017) Clinical, histological, and ultrasound follow-up of breast reconstruction with one-stage muscle-sparing \u201cwrap\u201d technique: a single-center experience. J Plast Reconstr Aesthetic Surg JPRAS 70(11):1527\u20131536. https:\/\/doi.org\/10.1016\/j.bjps.2017.06.023","journal-title":"J Plast Reconstr Aesthetic Surg JPRAS"},{"issue":"3","key":"1616_CR29","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1007\/s00266-019-01311-x","volume":"43","author":"M Marcasciano","year":"2019","unstructured":"Marcasciano M, Frattaroli J, Mori FLR et al (2019) The new trend of pre-pectoral breast reconstruction: an objective evaluation of the quality of online information for patients undergoing breast reconstruction. Aesthetic Plast Surg 43(3):593\u2013599. https:\/\/doi.org\/10.1007\/s00266-019-01311-x","journal-title":"Aesthetic Plast Surg"},{"key":"1616_CR30","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2018.12.018","author":"D Casella","year":"2018","unstructured":"Casella D, Di Taranto G, Marcasciano M et al (2018) Subcutaneous expanders and synthetic mesh for breast reconstruction: long-term and patient-reported BREAST-Q outcomes of a single-center prospective study. J Plast Reconstr Aesthetic Surg JPRAS. https:\/\/doi.org\/10.1016\/j.bjps.2018.12.018","journal-title":"J Plast Reconstr Aesthetic Surg JPRAS"},{"issue":"1","key":"1616_CR31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/PRS.0000000000004453","volume":"142","author":"SM Elswick","year":"2018","unstructured":"Elswick SM, Harless CA, Bishop SN et al (2018) Prepectoral implant-based breast reconstruction with postmastectomy radiation therapy. Plast Reconstr Surg 142(1):1\u201312. https:\/\/doi.org\/10.1097\/PRS.0000000000004453","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"1616_CR32","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1097\/PRS.0000000000005140","volume":"143","author":"H Sbitany","year":"2019","unstructured":"Sbitany H, Gomez-Sanchez C, Piper M, Lentz R (2019) Prepectoral breast reconstruction in the setting of postmastectomy radiation therapy: an assessment of clinical outcomes and benefits. Plast Reconstr Surg 143(1):10\u201320. https:\/\/doi.org\/10.1097\/PRS.0000000000005140","journal-title":"Plast Reconstr Surg"},{"key":"1616_CR33","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1186\/s12957-016-0874-9","volume":"14","author":"HL Ellis","year":"2016","unstructured":"Ellis HL, Asaolu O, Nebo V, Kasem A (2016) Biological and synthetic mesh use in breast reconstructive surgery: a literature review. World J Surg Oncol 14:121. https:\/\/doi.org\/10.1186\/s12957-016-0874-9","journal-title":"World J Surg Oncol"},{"issue":"5","key":"1616_CR34","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1097\/PRS.0b013e31824a2b02","volume":"129","author":"HR Moyer","year":"2012","unstructured":"Moyer HR, Losken A (2012) Predicting mastectomy skin flap necrosis with indocyanine green angiography: the gray area defined. Plast Reconstr Surg 129(5):1043\u20131048. https:\/\/doi.org\/10.1097\/PRS.0b013e31824a2b02","journal-title":"Plast Reconstr Surg"},{"issue":"4","key":"1616_CR35","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1097\/PRS.0b013e3181d17f80","volume":"125","author":"E Komorowska-Timek","year":"2010","unstructured":"Komorowska-Timek E, Gurtner GC (2010) Intraoperative perfusion mapping with laser-assisted indocyanine green imaging can predict and prevent complications in immediate breast reconstruction. Plast Reconstr Surg 125(4):1065\u20131073. https:\/\/doi.org\/10.1097\/PRS.0b013e3181d17f80","journal-title":"Plast Reconstr Surg"}],"container-title":["Aesthetic Plastic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00266-020-01616-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00266-020-01616-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00266-020-01616-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T00:40:28Z","timestamp":1611189628000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00266-020-01616-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,22]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["1616"],"URL":"https:\/\/doi.org\/10.1007\/s00266-020-01616-2","relation":{},"ISSN":["0364-216X","1432-5241"],"issn-type":[{"value":"0364-216X","type":"print"},{"value":"1432-5241","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,22]]},"assertion":[{"value":"1 November 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 January 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 January 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"All authors hereby declare not to have any potential conflict of interests and not to have received funding for this work. Each author participated sufficiently in the work to take public responsibility for the content and agree to its publication.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study followed the declaration of Helsinki on medical protocols and ethics, and the ethical review board of our institution had already approved the use of acellular dermal matrix for breast reconstruction.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Informed consent was obtained from all patients.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}}]}}