{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T14:50:25Z","timestamp":1791989425950,"version":"4.4.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T00:00:00Z","timestamp":1627862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T00:00:00Z","timestamp":1627862400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Aesth Plast Surg"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1007\/s00266-021-02483-1","type":"journal-article","created":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T16:02:47Z","timestamp":1627920167000},"page":"385-394","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":61,"title":["Avoiding Complications on the Upper Face Treatment With Botulinum Toxin: A Practical Guide"],"prefix":"10.1007","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2293-1119","authenticated-orcid":false,"given":"Andr\u00e9","family":"Borba","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzana","family":"Matayoshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matheus","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,8,2]]},"reference":[{"key":"2483_CR1","doi-asserted-by":"publisher","first-page":"393e","DOI":"10.1097\/PRS.0000000000003646","volume":"140","author":"M de Maio","year":"2017","unstructured":"de Maio M, Wu WTL, Goodman GJ, Monheit G (2017) Facial assessment and injection guide for Botulinum Toxin and injectable hyaluronic acid fillers: Focus on the Lower Face. Plast Reconstr Surg 140:393e\u2013404e. https:\/\/doi.org\/10.1097\/PRS.0000000000003646","journal-title":"Plast Reconstr Surg"},{"key":"2483_CR2","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.cxom.2016.05.006","volume":"24","author":"C Qaqish","year":"2016","unstructured":"Qaqish C (2016) Botulinum toxin use in the upper face. Atlas Oral Maxillofac Surg Clin 24:95\u2013103. https:\/\/doi.org\/10.1016\/j.cxom.2016.05.006","journal-title":"Atlas Oral Maxillofac Surg Clin"},{"key":"2483_CR3","unstructured":"Borba A, Matayoshi S (2018) Facial rejuvenation techniques: botulinum toxin and MD Codes TM, 1st edn. Buzz Editor Ltda, S\u00e3o Paulo (Brazil)"},{"key":"2483_CR4","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/j.fsc.2015.01.010","volume":"23","author":"BP Erickson","year":"2015","unstructured":"Erickson BP, Lee WW, Cohen J, Grunebaum LD (2015) The role of neurotoxins in the periorbital and midfacial areas. Facial Plast Surg Clin North Am 23:243\u2013255. https:\/\/doi.org\/10.1016\/j.fsc.2015.01.010","journal-title":"Facial Plast Surg Clin North Am"},{"key":"2483_CR5","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.clindermatol.2003.12.026","volume":"22","author":"AW Klein","year":"2004","unstructured":"Klein AW (2004) Contraindications and complications with the use of botulinum toxin. Clin Dermatol 22:66\u201375. https:\/\/doi.org\/10.1016\/j.clindermatol.2003.12.026","journal-title":"Clin Dermatol"},{"key":"2483_CR6","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1111\/j.1473-2165.2010.00545.x","volume":"10","author":"A Feily","year":"2011","unstructured":"Feily A, Fallahi H, Zandian D, Kalantar H (2011) A succinct review of botulinum toxin in dermatology; update of cosmetic and noncosmetic use. J Cosmet Dermatol 10:58\u201367. https:\/\/doi.org\/10.1111\/j.1473-2165.2010.00545.x","journal-title":"J Cosmet Dermatol"},{"key":"2483_CR7","doi-asserted-by":"publisher","first-page":"518e","DOI":"10.1097\/01.prs.0000475758.63709.23","volume":"137","author":"H Sundaram","year":"2016","unstructured":"Sundaram H, Signorini M, Liew S et al (2016) Global aesthetics consensus. Plast Reconstr Surg 137:518e\u2013529e. https:\/\/doi.org\/10.1097\/01.prs.0000475758.63709.23","journal-title":"Plast Reconstr Surg"},{"key":"2483_CR8","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1111\/jocd.13266","volume":"19","author":"M Kassir","year":"2020","unstructured":"Kassir M, Gupta M, Galadari H et al (2020) Complications of botulinum toxin and fillers: A narrative review. J Cosmet Dermatol 19:570\u2013573. https:\/\/doi.org\/10.1111\/jocd.13266","journal-title":"J Cosmet Dermatol"},{"key":"2483_CR9","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1053\/mda.2001.25964","volume":"48","author":"AW Klein","year":"2002","unstructured":"Klein AW (2002) Complications and adverse reactions with the use of botulinum toxin. Dis Mon 48:336\u2013356. https:\/\/doi.org\/10.1053\/mda.2001.25964","journal-title":"Dis Mon"},{"key":"2483_CR10","doi-asserted-by":"publisher","first-page":"265e","DOI":"10.1097\/PRS.0000000000003544","volume":"140","author":"M de Maio","year":"2017","unstructured":"de Maio M, Swift A, Signorini M, Fagien S (2017) Facial assessment and injection guide for Botulinum Toxin and injectable hyaluronic acid fillers. Plast Reconstr Surg 140:265e\u2013276e. https:\/\/doi.org\/10.1097\/PRS.0000000000003544","journal-title":"Plast Reconstr Surg"},{"key":"2483_CR11","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1111\/j.1524-4725.1998.tb04094.x","volume":"24","author":"AW Klein","year":"1998","unstructured":"Klein AW (1998) Dilution and storage of Botulinum Toxin. Dermatologic Surg 24:1179\u20131180. https:\/\/doi.org\/10.1111\/j.1524-4725.1998.tb04094.x","journal-title":"Dermatologic Surg"},{"key":"2483_CR12","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-020-01983-w","author":"N Sethi","year":"2020","unstructured":"Sethi N, Singh S, DeBoulle K, Rahman E (2020) A review of complications due to the use of Botulinum Toxin A for cosmetic indications. Aesthetic Plast Surg. https:\/\/doi.org\/10.1007\/s00266-020-01983-w","journal-title":"Aesthetic Plast Surg"},{"key":"2483_CR13","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1007\/s00266-016-0682-1","volume":"40","author":"Z Jia","year":"2016","unstructured":"Jia Z, Lu H, Yang X et al (2016) Adverse events of Botulinum Toxin type A in facial rejuvenation: a systematic review and meta-analysis. Aesthetic Plast Surg 40:769\u2013777. https:\/\/doi.org\/10.1007\/s00266-016-0682-1","journal-title":"Aesthetic Plast Surg"},{"key":"2483_CR14","doi-asserted-by":"crossref","unstructured":"Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (eds) (2019) Cochrane handbook for systematic reviews of interventions, 2nd edn. John Wiley & Sons, Chichester (UK)","DOI":"10.1002\/9781119536604"},{"key":"2483_CR15","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1007\/s00266-004-0031-7","volume":"28","author":"MC Ferreira","year":"2004","unstructured":"Ferreira MC, Salles AG, Gimenez R, Soares MFD (2004) Complications with the use of Botulinum Toxin Type A in facial rejuvenation: report of 8 Cases. Aesthetic Plast Surg 28:441\u2013444. https:\/\/doi.org\/10.1007\/s00266-004-0031-7","journal-title":"Aesthetic Plast Surg"},{"key":"2483_CR16","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1111\/j.1526-4637.2005.05029.x","volume":"6","author":"S Omoigui","year":"2005","unstructured":"Omoigui S, Irene S (2005) Treatment of ptosis as a complication of Botulinum Toxin Injection. Pain Med 6:149\u2013151. https:\/\/doi.org\/10.1111\/j.1526-4637.2005.05029.x","journal-title":"Pain Med"},{"key":"2483_CR17","doi-asserted-by":"publisher","first-page":"1189","DOI":"10.1111\/j.1524-4725.1998.tb04097.x","volume":"24","author":"A Carruthers","year":"1998","unstructured":"Carruthers A, CARRUTHERS J, (1998) Clinical indications and injection technique for the cosmetic use of Botulinum A Exotoxin. Dermatologic Surg 24:1189\u20131194. https:\/\/doi.org\/10.1111\/j.1524-4725.1998.tb04097.x","journal-title":"Dermatologic Surg"},{"key":"2483_CR18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.fsc.2004.04.008","volume":"13","author":"AJ Vartanian","year":"2005","unstructured":"Vartanian AJ, Dayan SH (2005) Complications of botulinum toxin A use in facial rejuvenation. Facial Plast Surg Clin North Am 13:1\u201310. https:\/\/doi.org\/10.1016\/j.fsc.2004.04.008","journal-title":"Facial Plast Surg Clin North Am"},{"key":"2483_CR19","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1053\/sder.2001.25964","volume":"20","author":"AW Klein","year":"2001","unstructured":"Klein AW (2001) Complications and adverse reactions with the use of botulinum toxin. Semin Cutan Med Surg 20:109\u2013120. https:\/\/doi.org\/10.1053\/sder.2001.25964","journal-title":"Semin Cutan Med Surg"},{"key":"2483_CR20","doi-asserted-by":"publisher","first-page":"106","DOI":"10.3109\/14764170903480013","volume":"12","author":"NJ Lowe","year":"2010","unstructured":"Lowe NJ, Shah A, Lowe PL, Patnaik R (2010) Dosing, efficacy and safety plus the use of computerized photography for botulinum toxins type A for upper facial lines. J Cosmet Laser Ther 12:106\u2013111. https:\/\/doi.org\/10.3109\/14764170903480013","journal-title":"J Cosmet Laser Ther"},{"key":"2483_CR21","first-page":"486","volume":"14","author":"EP Sorensen","year":"2015","unstructured":"Sorensen EP, Urman C (2015) Cosmetic complications: rare and serious events following botulinum toxin and soft tissue filler administration. J Drugs Dermatol 14:486\u2013491","journal-title":"J Drugs Dermatol"},{"key":"2483_CR22","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1007\/s00266-016-0712-z","volume":"40","author":"AC Abramo","year":"2016","unstructured":"Abramo AC, Do Amaral TPA, Lessio BP, De Lima GA (2016) Anatomy of forehead, glabellar, nasal and orbital muscles, and their correlation with distinctive patterns of skin lines on the upper third of the face: reviewing concepts. Aesthetic Plast Surg 40:962\u2013971. https:\/\/doi.org\/10.1007\/s00266-016-0712-z","journal-title":"Aesthetic Plast Surg"},{"key":"2483_CR23","doi-asserted-by":"publisher","first-page":"1553","DOI":"10.1111\/j.1524-4725.2011.02087.x","volume":"37","author":"A Trindade De Almeida","year":"2011","unstructured":"Trindade De Almeida A, Secco L, Carruthers A (2011) Handling Botulinum toxins. Dermatologic Surg 37:1553\u20131565. https:\/\/doi.org\/10.1111\/j.1524-4725.2011.02087.x","journal-title":"Dermatologic Surg"},{"issue":"3","key":"2483_CR24","first-page":"191","volume":"2","author":"AV Braz","year":"2010","unstructured":"Braz AV, Sakuma TH (2010) Patterns of contraction of the frontalis muscle: a pilot study. Surg Cosmet Dermatol 2(3):191\u2013194","journal-title":"Surg Cosmet Dermatol"},{"key":"2483_CR25","doi-asserted-by":"publisher","first-page":"2168","DOI":"10.1111\/j.1524-4725.2010.01708.x","volume":"36","author":"A Carruthers","year":"2010","unstructured":"Carruthers A, Carruthers J, Lei X et al (2010) OnabotulinumtoxinA treatment of mild Glabellar lines in repose. Dermatologic Surg 36:2168\u20132171. https:\/\/doi.org\/10.1111\/j.1524-4725.2010.01708.x","journal-title":"Dermatologic Surg"},{"key":"2483_CR26","doi-asserted-by":"publisher","first-page":"1794","DOI":"10.1111\/j.1524-4725.2012.02582.x","volume":"38","author":"R Glogau","year":"2012","unstructured":"Glogau R, Kane M, Beddingfield F et al (2012) OnabotulinumtoxinA: a meta-analysis of duration of effect in the treatment of Glabellar Lines. Dermatologic Surg 38:1794\u20131803. https:\/\/doi.org\/10.1111\/j.1524-4725.2012.02582.x","journal-title":"Dermatologic Surg"},{"key":"2483_CR27","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1046\/j.1524-4725.2003.29112.x","volume":"29","author":"J Charles Finn","year":"2003","unstructured":"Charles Finn J, Cox SE, Earl ML (2003) Social implications of hyperfunctional facial lines. Dermatologic Surg 29:450\u2013455. https:\/\/doi.org\/10.1046\/j.1524-4725.2003.29112.x","journal-title":"Dermatologic Surg"},{"key":"2483_CR28","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1097\/00006534-200107000-00033","volume":"108","author":"SL Matarasso","year":"2001","unstructured":"Matarasso SL, Matarasso A (2001) Treatment guidelines for Botulinum Toxin Type A for the periocular region and a report on partial upper lip ptosis following injections to the lateral Canthal Rhytids. Plast Reconstr Surg 108:208\u2013214. https:\/\/doi.org\/10.1097\/00006534-200107000-00033","journal-title":"Plast Reconstr Surg"}],"container-title":["Aesthetic Plastic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00266-021-02483-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00266-021-02483-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00266-021-02483-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T05:35:30Z","timestamp":1744176930000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00266-021-02483-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,2]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["2483"],"URL":"https:\/\/doi.org\/10.1007\/s00266-021-02483-1","relation":{},"ISSN":["0364-216X","1432-5241"],"issn-type":[{"value":"0364-216X","type":"print"},{"value":"1432-5241","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,2]]},"assertion":[{"value":"5 May 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 July 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 August 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Dr. Andr\u00e9 Borba reports grants from Allergan, Inc. as a speaker. There are no conflicts of interest to declare regarding this article. Dr. Suzana Matayoshi has nothing to disclose. Matheus Rodrigues has nothing to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Patients provided written consent for the use of their images.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}