{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:43:26Z","timestamp":1760147006983,"version":"build-2065373602"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"18","license":[{"start":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T00:00:00Z","timestamp":1747612800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T00:00:00Z","timestamp":1747612800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005296","name":"Universit\u00e4tsklinikum Regensburg","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005296","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Aesth Plast Surg"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Lip augmentation is a highly demanded cosmetic procedure due to the association of full lips with youth, beauty, and sensuality. Among various techniques, autologous fat grafting, particularly with the cell-enriched lipotransfer (CELT) method, has emerged as a natural and long-lasting option. Unlike hyaluronic acid fillers, which require regular touch-ups, CELT offers sustained volume retention and potentially higher patient satisfaction.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>This study aimed to assess patient satisfaction following lip augmentation using the CELT technique and compare it with traditional fat preparation methods, such as sedimentation and filtration. The study also sought to evaluate the influence of other variables, including gender, age, and fat injection volume, on satisfaction outcomes.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Materials and Methods<\/jats:title>\n            <jats:p>A retrospective chart review of patients who underwent lip augmentation with autologous fat grafting was conducted. Satisfaction was measured using the FACE-Q<jats:sup>TM<\/jats:sup> questionnaire, focusing on various lip-related aspects such as shape, fullness, and how well the lips suited the face. The study compared satisfaction outcomes between the CELT method and combined sedimentation\/filtration techniques. Statistical analysis using the Kruskal\u2013Wallis test and Pearson's correlation was performed to assess the influence of preparation method, injected volume, and patient demographics.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The CELT method consistently produced higher satisfaction compared to sedimentation and filtration (<jats:italic>p<\/jats:italic> &lt; 0.001 for all items). Patients treated with CELT reported greater improvements in the shape of the lips, fullness of the lower lip, and Cupid\u2019s bow. Gender and age were also significant factors, with males showing greater satisfaction in smile-related aspects, while females were more satisfied with the lip style. Older patients reported greater improvements in how well their lips suited their face, while higher injected volumes positively correlated with lip fullness and appearance.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>The CELT fat grafting technique significantly enhances patient satisfaction in lip augmentation compared to traditional fat preparation methods. CELT's higher fat retention and more natural results make it a superior option for lip augmentation. However, further studies incorporating objective volumetric measurements are needed to validate these findings.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Level of Evidence IV<\/jats:title>\n            <jats:p>This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.springer.com\/00266\" ext-link-type=\"uri\">www.springer.com\/00266<\/jats:ext-link>.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00266-025-04875-z","type":"journal-article","created":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T12:03:42Z","timestamp":1747656222000},"page":"5111-5119","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Subject-Reported Satisfaction After Cell-Enriched Lipotransfer (CELT) for Lip Augmentation"],"prefix":"10.1007","volume":"49","author":[{"given":"Sophia","family":"Diesch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6994-8877","authenticated-orcid":false,"given":"Konstantin","family":"Frank","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa","family":"Br\u00e9bant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Bohusch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Brix","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukas","family":"Prantl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,5,19]]},"reference":[{"issue":"21","key":"4875_CR1","doi-asserted-by":"publisher","first-page":"4601","DOI":"10.1007\/s00266-024-04355-w","volume":"48","author":"L Triana","year":"2024","unstructured":"Triana L, Palacios RM, Huatuco GC, Liscano E. Correction: trends in surgical and nonsurgical aesthetic procedures: a 14-year analysis of the International Society of Aesthetic Plastic Surgery\u2014ISAPS. Aesthet Plast Surg. 2024;48(21):4601\u20134601. https:\/\/doi.org\/10.1007\/s00266-024-04355-w.","journal-title":"Aesthet Plast Surg"},{"key":"4875_CR2","unstructured":"Tabassum N, Jasthi VC, Al Salem A, et al. Perspectives and challenges in lip rejuvenation: a systematic review. Eur Rev Med Pharmacol Sci. 2023; 27(19)."},{"issue":"5","key":"4875_CR3","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1097\/PRS.0000000000005589","volume":"143","author":"PL Tonnard","year":"2019","unstructured":"Tonnard PL, Verpaele AM, Ramaut LE, Blondeel PN. Aging of the upper lip: part II. Evidence-based rejuvenation of the upper lip\u2014a review of 500 consecutive cases. 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