{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T16:12:19Z","timestamp":1779120739198,"version":"3.51.4"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82572687"],"award-info":[{"award-number":["82572687"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Aesth Plast Surg"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1007\/s00266-025-05603-3","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T20:32:20Z","timestamp":1768249940000},"page":"3438-3447","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Factors Associated with the Severity of Female Pattern Hair Loss: A Retrospective Study"],"prefix":"10.1007","volume":"50","author":[{"given":"Meiling","family":"Jian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingang","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuheng","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyu","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhibin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,1,12]]},"reference":[{"issue":"1","key":"5603_CR1","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1007\/s40257-019-00479-x","volume":"21","author":"M Starace","year":"2020","unstructured":"Starace M, Orlando G, Alessandrini A, Piraccini BM. Female androgenetic alopecia: an update on diagnosis and management. Am J Clin Dermatol. 2020;21(1):69\u201384.","journal-title":"Am J Clin Dermatol"},{"issue":"3","key":"5603_CR2","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1111\/jdv.15327","volume":"33","author":"PM Russo","year":"2019","unstructured":"Russo PM, Fino E, Mancini C, Mazzetti M, Starace M, Piraccini BM. HrQoL in hair loss-affected patients with alopecia areata, androgenetic alopecia and telogen effluvium: the role of personality traits and psychosocial anxiety. J Eur Acad Dermatol Venereol. 2019;33(3):608\u201311.","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"5603_CR3","first-page":"1","volume":"86","author":"NN Lang","year":"2016","unstructured":"Lang NN, Huang T, Song ZQ, Yang L, Zhou XC. Illness perception in patients with androgenetic alopecia and alopecia areata in China. J Psychosom Res. 2016;86:1\u20136.","journal-title":"J Psychosom Res"},{"issue":"4","key":"5603_CR4","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1111\/j.1365-2133.2010.09640.x","volume":"162","author":"TL Wang","year":"2010","unstructured":"Wang TL, Zhou C, Shen YW, Wang XY, Ding XL, Tian S, et al. Prevalence of androgenetic alopecia in China: a community-based study in six cities. Br J Dermatol. 2010;162(4):843\u20137.","journal-title":"Br J Dermatol"},{"issue":"8","key":"5603_CR5","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.1111\/jdv.12034","volume":"27","author":"WS Lee","year":"2013","unstructured":"Lee WS, Lee HJ, Choi GS, Cheong WK, Chow SK, Gabriel MT, et al. Guidelines for management of androgenetic alopecia based on BASP classification\u2014the Asian consensus committee guideline. J Eur Acad Dermatol Venereol. 2013;27(8):1026\u201334.","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"5","key":"5603_CR6","doi-asserted-by":"publisher","first-page":"622","DOI":"10.23736\/S0392-0488.19.06399-5","volume":"155","author":"A Alessandrini","year":"2020","unstructured":"Alessandrini A, Starace M, D\u2019Ovidio R, Villa L, Rossi A, Stan TR, et al. Androgenetic alopecia in women and men: Italian guidelines adapted from European dermatology forum\/European academy of dermatology and venereology guidelines. G Ital Dermatol Venereol. 2020;155(5):622\u201331.","journal-title":"G Ital Dermatol Venereol"},{"issue":"5","key":"5603_CR7","first-page":"12","volume":"38","author":"JF Zhang","year":"2022","unstructured":"Zhang JF, Wu WY. Chinese consensus on the diagnosis and treatment of female androgenetic alopecia. Chin J Plast Surg. 2022;38(5):12.","journal-title":"Chin J Plast Surg"},{"issue":"5","key":"5603_CR8","first-page":"331","volume":"33","author":"XH Liu","year":"2020","unstructured":"Liu XH, Liang F, Jia XY, Zhao L, Zhou Y, Yang J. Hyperbaric oxygen treatment improves hearing level via attenuating TLR4\/NF-\u03baB mediated inflammation in sudden sensorineural hearing loss patients. Biomed Environ Sci. 2020;33(5):331\u20137.","journal-title":"Biomed Environ Sci"},{"issue":"5","key":"5603_CR9","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1007\/s00266-023-03603-9","volume":"48","author":"M Li","year":"2023","unstructured":"Li M, Qu K, Lei Q, Chen M, Bian D. Effectiveness of platelet-rich plasma in the treatment of androgenic alopecia: a meta-analysis. Aesthet Plast Surg. 2023;48(5):977\u201384.","journal-title":"Aesthet Plast Surg"},{"key":"5603_CR10","doi-asserted-by":"publisher","first-page":"102491","DOI":"10.1016\/j.pdpdt.2021.102491","volume":"36","author":"Z Cao","year":"2021","unstructured":"Cao Z, Liu XJ, Zhang LL, Zhang YF, Zhou ZX, Zhang GL, et al. Treatment of androgenetic alopecia with 5-aminolevulinic acid photodynamic therapy: a randomized, placebo-controlled, split-scalp study of efficacy and safety. Photodiagnosis Photodyn Ther. 2021;36:102491.","journal-title":"Photodiagnosis Photodyn Ther"},{"issue":"19","key":"5603_CR11","doi-asserted-by":"publisher","first-page":"3735","DOI":"10.1007\/s00266-024-04305-6","volume":"48","author":"F Ceran","year":"2024","unstructured":"Ceran F. Recipient site necrosis after follicular unit excision technique for hair transplantation: evaluation of 18 patients. Aesthet Plast Surg. 2024;48(19):3735\u201340.","journal-title":"Aesthet Plast Surg"},{"key":"5603_CR12","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.cca.2021.10.004","volume":"523","author":"Y Hobo","year":"2021","unstructured":"Hobo Y, Nishikawa J, Miyashiro Y, Fujikata A. Analysis of hair steroid hormone concentrations at different parts of the head by liquid chromatography-tandem mass spectrometry. Clin Chim Acta. 2021;523:260\u20136.","journal-title":"Clin Chim Acta"},{"issue":"2","key":"5603_CR13","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1111\/jdv.17738","volume":"36","author":"BM Piraccini","year":"2022","unstructured":"Piraccini BM, Blume-Peytavi U, Scarci F, Jansat JM, Falques M, Otero R, et al. Efficacy and safety of topical finasteride spray solution for male androgenetic alopecia: a phase III, randomized, controlled clinical trial. J Eur Acad Dermatol Venereol. 2022;36(2):286\u201394.","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"2","key":"5603_CR14","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1111\/1346-8138.14719","volume":"46","author":"JW Shin","year":"2019","unstructured":"Shin JW, Chung EH, Kim MB, Kim TO, Kim WI, Huh CH. Evaluation of long-term efficacy of finasteride in Korean men with androgenetic alopecia using the basic and specific classification system. J Dermatol. 2019;46(2):139\u201343.","journal-title":"J Dermatol"},{"key":"5603_CR15","doi-asserted-by":"publisher","first-page":"117456","DOI":"10.1016\/j.cca.2023.117456","volume":"547","author":"Y Hobo","year":"2023","unstructured":"Hobo Y, Nishikawa J, Taniguchi Asai N, Yoneyama K, Watanabe Y, Miyashiro Y, et al. Evaluation of the therapeutic effects of AGA drugs by measuring finasteride, dutasteride, and dihydrotestosterone in hair. Clin Chim Acta. 2023;547:117456\u201361.","journal-title":"Clin Chim Acta"},{"issue":"4","key":"5603_CR16","doi-asserted-by":"publisher","first-page":"300","DOI":"10.21037\/tp.2017.09.08","volume":"6","author":"M Lause","year":"2017","unstructured":"Lause M, Kamboj A, Fernandez Faith E. Dermatologic manifestations of endocrine disorders. Transl Pediatr. 2017;6(4):300\u201312.","journal-title":"Transl Pediatr"},{"issue":"5","key":"5603_CR17","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1007\/s43440-021-00295-3","volume":"73","author":"R Krysiak","year":"2021","unstructured":"Krysiak R, Kowalcze K, Okopien B. The impact of exogenous vitamin D on thyroid autoimmunity in euthyroid men with autoimmune thyroiditis and early-onset androgenic alopecia. Pharmacol Rep. 2021;73(5):1439\u201347.","journal-title":"Pharmacol Rep"},{"issue":"2","key":"5603_CR18","doi-asserted-by":"publisher","first-page":"123","DOI":"10.4103\/0974-7753.58555","volume":"1","author":"A Rakowska","year":"2009","unstructured":"Rakowska A, Slowinska M, Kowalska-Oledzka E, Olszewska M, Rudnicka L. Dermoscopy in female androgenic alopecia: method standardization and diagnostic criteria. Int J Trichol. 2009;1(2):123\u201332.","journal-title":"Int J Trichol"},{"key":"5603_CR19","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.clinbiochem.2020.05.002","volume":"82","author":"K L.","year":"2020","unstructured":"Johnson-Davis KL, Farnsworth C, Law C, Parker R. Method validation for a multi-element panel in serum by inductively coupled plasma mass spectrometry (ICP-MS). Clin Biochem. 2020;82:90\u20138.","journal-title":"Clin Biochem"},{"issue":"1","key":"5603_CR20","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1007\/s13181-010-0113-7","volume":"7","author":"C Sobin","year":"2011","unstructured":"Sobin C, Parisi N, Schaub T, de la Riva E. A Bland-Altman comparison of the Lead Care(R) System and inductively coupled plasma mass spectrometry for detecting low-level lead in child whole blood samples. J Med Toxicol. 2011;7(1):24\u201332.","journal-title":"J Med Toxicol"},{"issue":"1","key":"5603_CR21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5826\/dpc.0701a01","volume":"7","author":"EL Guo","year":"2017","unstructured":"Guo EL, Katta R. Diet and hair loss: effects of nutrient deficiency and supplement use. Dermatol Pract Concept. 2017;7(1):1\u201310.","journal-title":"Dermatol Pract Concept"},{"issue":"1","key":"5603_CR22","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/s12863-021-01018-6","volume":"23","author":"K Furuya","year":"2022","unstructured":"Furuya K, Fujibayashi S, Wu T, Takahashi K, Takase S, Orimoto A, et al. Transcriptome analysis to identify the downstream genes of androgen receptor in dermal papilla cells. BMC Genom Data. 2022;23(1):2\u201312.","journal-title":"BMC Genom Data"},{"key":"5603_CR23","doi-asserted-by":"publisher","first-page":"127007","DOI":"10.1016\/j.jtemb.2022.127007","volume":"73","author":"E Inan Yuksel","year":"2022","unstructured":"Inan Yuksel E, Demir B, Cicek D, Sahin K, Tuzcu M, Orhan C, et al. Sodium pentaborate pentahydrate promotes hair growth through the Wnt\/beta-catenin pathway and growth factors. J Trace Elem Med Biol. 2022;73:127007\u201315.","journal-title":"J Trace Elem Med Biol"},{"issue":"9","key":"5603_CR24","doi-asserted-by":"publisher","first-page":"1113","DOI":"10.1111\/ijd.14982","volume":"59","author":"S Sanke","year":"2020","unstructured":"Sanke S, Samudrala S, Yadav A, Chander R, Goyal R. Study of serum vitamin D levels in men with premature androgenetic alopecia. Int J Dermatol. 2020;59(9):1113\u20136.","journal-title":"Int J Dermatol"},{"issue":"2","key":"5603_CR25","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1159\/000346698","volume":"26","author":"H Rasheed","year":"2013","unstructured":"Rasheed H, Mahgoub D, Hegazy R, El-Komy M, Abdel Hay R, Hamid MA, et al. Serum ferritin and vitamin d in female hair loss: do they play a role? Skin Pharmacol Physiol. 2013;26(2):101\u20137.","journal-title":"Skin Pharmacol Physiol"},{"issue":"3","key":"5603_CR26","doi-asserted-by":"publisher","first-page":"116","DOI":"10.4103\/0974-7753.188965","volume":"8","author":"M Banihashemi","year":"2016","unstructured":"Banihashemi M, Nahidi Y, Meibodi NT, Jarahi L, Dolatkhah M. Serum vitamin D3 level in patients with female pattern hair loss. Int J Trichology. 2016;8(3):116\u201320.","journal-title":"Int J Trichology"},{"issue":"9","key":"5603_CR27","doi-asserted-by":"publisher","first-page":"3232","DOI":"10.1007\/s12011-020-02468-2","volume":"199","author":"IN Kondrakhina","year":"2021","unstructured":"Kondrakhina IN, Verbenko DA, Zatevalov AM, Gatiatulina ER, Nikonorov AA, Deryabin DG, et al. A cross-sectional study of plasma trace elements and vitamins content in androgenetic alopecia in men. Biol Trace Elem Res. 2021;199(9):3232\u201341.","journal-title":"Biol Trace Elem Res"},{"issue":"3","key":"5603_CR28","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.jtemb.2014.03.003","volume":"28","author":"P Ozturk","year":"2014","unstructured":"Ozturk P, Kurutas E, Ataseven A, Dokur N, Gumusalan Y, Gorur A, et al. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia. J Trace Elem Med Biol. 2014;28(3):266\u201370.","journal-title":"J Trace Elem Med Biol"},{"issue":"1","key":"5603_CR29","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.jaad.2005.07.001","volume":"55","author":"VH Price","year":"2006","unstructured":"Price VH, Menefee E, Sanchez M, Kaufman KD. Changes in hair weight in men with androgenetic alopecia after treatment with finasteride (1 mg daily): three- and 4-year results. J Am Acad Dermatol. 2006;55(1):71\u20134.","journal-title":"J Am Acad Dermatol"},{"issue":"6","key":"5603_CR30","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1097\/MED.0000000000000777","volume":"29","author":"VS Jiang","year":"2022","unstructured":"Jiang VS, Hawkins SD, McMichael A. Female pattern hair loss and polycystic ovarian syndrome: more than just hirsutism. Curr Opin Endocrinol Diabetes Obes. 2022;29(6):535\u201340.","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"key":"5603_CR31","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.jtemb.2019.01.002","volume":"52","author":"M Abedini","year":"2019","unstructured":"Abedini M, Ghaedi E, Hadi A, Mohammadi H, Amani R. Zinc status and polycystic ovarian syndrome: a systematic review and meta-analysis. J Trace Elem Med Biol. 2019;52:216\u201321.","journal-title":"J Trace Elem Med Biol"},{"issue":"1","key":"5603_CR32","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1186\/s12958-022-00982-7","volume":"20","author":"M Jaripur","year":"2022","unstructured":"Jaripur M, Ghasemi-Tehrani H, Askari G, Gholizadeh-Moghaddam M, Clark CCT, Rouhani MH. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial. Reprod Biol Endocrinol. 2022;20(1):110\u201321.","journal-title":"Reprod Biol Endocrinol"},{"issue":"1","key":"5603_CR33","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.jaad.2010.05.005","volume":"65","author":"WS Lee","year":"2011","unstructured":"Lee WS, Oh Y, Ji JH, Park JK, Kim DW, Sim WY, et al. Analysis of familial factors using the basic and specific (BASP) classification in Korean patients with androgenetic alopecia. J Am Acad Dermatol. 2011;65(1):40\u20137.","journal-title":"J Am Acad Dermatol"},{"issue":"4","key":"5603_CR34","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1007\/s40618-022-01944-x","volume":"46","author":"C Cocchetti","year":"2023","unstructured":"Cocchetti C, Castellini G, Maggi M, Romani A, Vignozzi L, Greenman Y, et al. Effects of hormonal treatment on dermatological outcome in transgender people: a multicentric prospective study (ENIGI). J Endocrinol Invest. 2023;46(4):779\u201386.","journal-title":"J Endocrinol Invest"},{"issue":"2","key":"5603_CR35","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/j.det.2019.10.010","volume":"38","author":"DH Marks","year":"2020","unstructured":"Marks DH, Senna MM. Androgenetic alopecia in gender minority patients. Dermatol Clin. 2020;38(2):239\u201347.","journal-title":"Dermatol Clin"},{"issue":"2","key":"5603_CR36","doi-asserted-by":"publisher","first-page":"e69","DOI":"10.1016\/j.jaad.2012.09.046","volume":"69","author":"LH Su","year":"2013","unstructured":"Su LH, Chen LS, Chen HH. Factors associated with female pattern hair loss and its prevalence in Taiwanese women: a community-based survey. J Am Acad Dermatol. 2013;69(2):e69-77.","journal-title":"J Am Acad Dermatol"},{"issue":"4","key":"5603_CR37","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1111\/j.1365-2133.2009.09588.x","volume":"162","author":"S Arias-Santiago","year":"2010","unstructured":"Arias-Santiago S, Guti\u00e9rrez-Salmer\u00f3n MT, Buend\u00eda-Eisman A, Gir\u00f3n-Prieto MS, Naranjo-Sintes R. Hypertension and aldosterone levels in women with early-onset androgenetic alopecia. Br J Dermatol. 2010;162(4):786\u20139.","journal-title":"Br J Dermatol"}],"container-title":["Aesthetic Plastic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00266-025-05603-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00266-025-05603-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00266-025-05603-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T15:59:03Z","timestamp":1779119943000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00266-025-05603-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,12]]},"references-count":37,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["5603"],"URL":"https:\/\/doi.org\/10.1007\/s00266-025-05603-3","relation":{},"ISSN":["0364-216X","1432-5241"],"issn-type":[{"value":"0364-216X","type":"print"},{"value":"1432-5241","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,12]]},"assertion":[{"value":"12 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study protocol was approved by the Ethics Committee of Sichuan Academy of Medical Sciences & Sichuan Provincial People\u2019s Hospital, and Individual informed consent was waived, as all patients had previously provided general informed consent for the use of their de-identified data for research purposes.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval and Informed Consent"}}]}}