{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T11:17:13Z","timestamp":1792581433912,"version":"4.5.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"15","license":[{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100002966","name":"Sivas Cumhuriyet University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002966","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Aesth Plast Surg"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Regional fascial plane blocks are widely used in breast surgery for postoperative analgesia. While analgesic benefits are established, their impact on early complications after reduction mammaplasty remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the association between regional fascial plane block use and early postoperative complications following superior pedicle reduction mammaplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study included 144 consecutive patients undergoing primary bilateral superior pedicle reduction mammaplasty at a single tertiary center. Patients were grouped as block (n=64) or no-block (n=80). All blocks were performed postoperatively at the end of surgery. The primary outcome was a 30-day composite complication, defined as hematoma requiring reoperation, wound dehiscence, or surgical site infection. Multivariable logistic regression assessed the independent association between block use and complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall, 55 patients (38.2%) developed at least one early postoperative complication. The composite complication rate was higher in the block group than in the no-block group (46.9% vs. 31.3%); however, this difference did not reach statistical significance (p=0.060). In multivariable analysis, block use was not independently associated with complications, whereas total excision weight was the only significant predictor. Hematomas occurred only in the block group (7.8% vs. 0%, p=0.016).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Regional fascial plane block use was not independently associated with overall postoperative morbidity after adjustment. Although hematomas were observed only in the block group, the low event rate and non-randomized design preclude causal inference. However, a relevant increase in overall complication risk cannot be ruled out; therefore, further prospective studies are needed to clarify this relationship.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence III<\/jats:title>\n                    <jats:p>\n                      This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.springer.com\/00266\" ext-link-type=\"uri\">www.springer.com\/00266<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00266-026-06068-8","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T17:53:15Z","timestamp":1781545995000},"page":"6082-6088","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Regional Fascial Plane Blocks and Early Postoperative Complications in Reduction Mammaplasty: A Retrospective Cohort Study"],"prefix":"10.1007","volume":"50","author":[{"given":"Handan","family":"Dereba\u015f\u0131nl\u0131o\u011flu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onur","family":"Avc\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2027-7843","authenticated-orcid":false,"given":"Murat","family":"\u00c7elik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mesut","family":"Da\u011fdeviren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"6068_CR1","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1097\/PRS.0000000000005907","volume":"144","author":"LC Nuzzi","year":"2019","unstructured":"Nuzzi LC, Firriolo JM, Pike CM, DiVasta AD, Labow BI. 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