{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T00:17:11Z","timestamp":1705018631107},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2002,3,1]],"date-time":"2002-03-01T00:00:00Z","timestamp":1014940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2002,3,1]],"date-time":"2002-03-01T00:00:00Z","timestamp":1014940800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2002,3]]},"abstract":"<jats:p>Gastric cancer is a disease in which themain treatment is surgical extirpation. The modifications introduced inthe surgical treatment over the last decades were accompanied by aclear increase of survival, which reaches global values of 61% at 5years in Japan. One of the reasons that contribute to this improvementis early diagnosis of the lesions. In the period between January 1,1990 and December 31, 1999 662 patients with gastric adenocarcinomawere treated in the Service of Surgery 1 of our hospital; 110 wererefused surgical treatment. Of the resected patients, 91 (21.4%) wereclassified as early gastric cancer according to the definition of theJapanese Society of Digestive Endoscopy. There were 30 women and 61men, with a median age of 60.2 \u00b1 15 years; 3 patients had apreoperative diagnosis of gastric ulcer; 2 others were operatedwithout recent histology; and 1 patient was urgently resected for ableeding ulcer. In all the remaining patients biopsy confirmed thepresence of cancer (89%) or serious dysplasia (4.6%). The lesions hadbeen distributed essentially in the medium 1\/3 (48.3%) anddistal 1\/3 of the stomach.%Subtotal gastrectomy was accomplished in 48 patients, total gastrectomyin 40, total desgastrogastrectomy in 3, and in 9 patients thesurgery involved the spleen (8 patients) and the spleen and tail of thepancreas in 1 patient. Lymphadenectomy was not performed in 5 patients,lymph nodes by the first lymph node barrier were removed in 25 patientsand by the second barrier in 61 patients (67%). Median tumor size was26 \u00b1 1.8\u00a0mm. The lesion reached the mucosa in 46 patients and themucosa and submucosa in 45. In 6 patients the removed lymph nodes weremicroscopically invaded (6.7%). Five patients died (5.7%). The medianfollow\u2010up of the patients is 41 \u00b1 26\u00a0months; 7 patients died(8.1%) during this period; 4 died unequivocally of diseaseprogression. The median survival of patients was 85% at 5 years and80% at 10 years. In our series, survival was affected by the presenceof invaded lymph nodes, not by the penetration in depth of the lesionor the size of the tumor.<\/jats:p>","DOI":"10.1007\/s00268-001-0228-8","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T06:16:17Z","timestamp":1030256177000},"page":"330-334","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Early Gastric Cancer: Ten years of Experience"],"prefix":"10.1002","volume":"26","author":[{"given":"Carlos","family":"Nogueira","sequence":"first","affiliation":[{"name":"Surgery Department, Surgery 1 Hospital Geral de Santo Ant\u00f3nio Largo Prof. Abel Salazar 4000 Oporto Portugal<!--<country1>PORTUGAL<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f3nio S\u00e9rgio","family":"Silva","sequence":"additional","affiliation":[{"name":"Surgery Department, Surgery 1 Hospital Geral de Santo Ant\u00f3nio Largo Prof. Abel Salazar 4000 Oporto Portugal<!--<country1>PORTUGAL<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge Nunes","family":"Santos","sequence":"additional","affiliation":[{"name":"Surgery Department, Surgery 1 Hospital Geral de Santo Ant\u00f3nio Largo Prof. Abel Salazar 4000 Oporto Portugal<!--<country1>PORTUGAL<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f3nio Gomes","family":"Silva","sequence":"additional","affiliation":[{"name":"Surgery Department, Surgery 1 Hospital Geral de Santo Ant\u00f3nio Largo Prof. Abel Salazar 4000 Oporto Portugal<!--<country1>PORTUGAL<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joaquim","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Surgery Department, Surgery 1 Hospital Geral de Santo Ant\u00f3nio Largo Prof. Abel Salazar 4000 Oporto Portugal<!--<country1>PORTUGAL<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduarda","family":"Matos","sequence":"additional","affiliation":[{"name":"Instituto de Ciencias Biom\u00e9dicas AbelSalazar Largo da Escola M\u00e9dica 4000 Oporto Portugal<!--<country1>PORTUGAL<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hernani","family":"Vila\u00e7a","sequence":"additional","affiliation":[{"name":"Surgery Department, Surgery 1 Hospital Geral de Santo Ant\u00f3nio Largo Prof. Abel Salazar 4000 Oporto Portugal<!--<country1>PORTUGAL<\/country1>-->"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,3]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-001-0228-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-001-0228-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-001-0228-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T20:02:11Z","timestamp":1705003331000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-001-0228-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,3]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2002,3]]}},"alternative-id":["10.1007\/s00268-001-0228-8"],"URL":"https:\/\/doi.org\/10.1007\/s00268-001-0228-8","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,3]]}}}