{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T09:06:14Z","timestamp":1792055174214,"version":"4.4.0"},"reference-count":0,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2002,8,1]],"date-time":"2002-08-01T00:00:00Z","timestamp":1028160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2002,8]]},"abstract":"<jats:p>\nA combination of preoperative localization and intraoperative parathormone (PTH) monitoring permits targeted parathyroidectomy. Multiple approaches have been developed,\nranging from unilateral neck exploration (UE) to radio\u2010guided parathyroidectomy (RP) to endoscopic parathyroidectomy (EP). The purpose of this study was to evaluate the efficacy of these approaches in the management of primary hyperparathyroidism. From June 1998 to November 2000 a total of 110 targeted parathyroid operations were performed at a university medical center. All patients underwent technetium\u201099m\u2010sestamibi scanning, ultrasonography, or both prior to surgery. Intraoperative PTH monitoring was utilized in all cases.\nThirty\u2010seven patients underwent UE, 59 underwent RP, and 14 underwent EP. Follow\u2010up ranged from 1 to 24\u00a0months. All patients were cured following parathyroidectomy as predicted by a more than 50% reduction of the intraoperative PTH level following removal of all hypersecreting glands. Altogether, 103 patients had a solitary adenoma (95%), and 1\npatient had a parathyroid carcinoma. Six patients (5%) had multigland disease, including four cases of hyperplasia and two patients with a double adenoma. Eighty\u2010three patients (75%) were discharged the day of surgery. The use of preoperative localization and intraoperative PTH monitoring permits a targeted approach to the treatment of primary hyperparathyroidism. Endocrine surgeons should be facile in all minimally invasive parathyroid techniques to individualize the operative approach.\n<\/jats:p>","DOI":"10.1007\/s00268-002-6619-7","type":"journal-article","created":{"date-parts":[[2002,10,14]],"date-time":"2002-10-14T16:45:16Z","timestamp":1034613916000},"page":"921-925","source":"Crossref","is-referenced-by-count":66,"title":["Targeted Parathyroidectomy in the Era of Intraoperative Parathormone Monitoring"],"prefix":"10.1002","volume":"26","author":[{"suffix":"III","given":"William B.","family":"Inabnet","sequence":"first","affiliation":[{"name":"Department of Surgery The Mount Sinai School of Medicine One Gustave L. Levy Place New York New York 10029 USA<!--<country1>USA<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory F.","family":"Dakin","sequence":"additional","affiliation":[{"name":"Department of Surgery The Mount Sinai School of Medicine One Gustave L. Levy Place New York New York 10029 USA<!--<country1>USA<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard S.","family":"Haber","sequence":"additional","affiliation":[{"name":"Division of Endocrinology Department of Medicine The Mount Sinai School of Medicine One Gustave L. Levy Place New York New York 10029 USA<!--<country1>USA<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Rubino","sequence":"additional","affiliation":[{"name":"Department of Surgery The Mount Sinai School of Medicine One Gustave L. Levy Place New York New York 10029 USA<!--<country1>USA<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ed J.","family":"Diamond","sequence":"additional","affiliation":[{"name":"Division of Endocrinology Department of Medicine The Mount Sinai School of Medicine One Gustave L. Levy Place New York New York 10029 USA<!--<country1>USA<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Gagner","sequence":"additional","affiliation":[{"name":"Department of Surgery The Mount Sinai School of Medicine One Gustave L. Levy Place New York New York 10029 USA<!--<country1>USA<\/country1>-->"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,8]]},"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-002-6619-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-002-6619-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-002-6619-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T20:18:24Z","timestamp":1703708304000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-002-6619-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,8]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2002,8]]}},"alternative-id":["10.1007\/s00268-002-6619-7"],"URL":"https:\/\/doi.org\/10.1007\/s00268-002-6619-7","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,8]]}}}