{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T05:24:23Z","timestamp":1774243463361,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2003,10,13]],"date-time":"2003-10-13T00:00:00Z","timestamp":1066003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2003,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The pylorus\u2010preserving pancreaticoduodenectomy (PPPD) is an alternative to the standard Whipple resection in the treatment of chronic pancreatitis. The operation is safe and can be performed with a low mortality rate. The most common early complication is delayed gastric emptying, which occurs in 25% to 30% of patients, and generally results in longer hospital stays than the standard Whipple procedure. Follow\u2010up studies show that both operations are equally effective in relieving pain in approximately 75% of selected patients. In the long term, the PPPD successfully preserves physiologic gastric emptying, but at the cost of a higher marginal ulceration rate. The purported nutritional advantages of the PPPD over the classic Whipple resection have not been clearly established. At present, the PPPD is the procedure of choice for patients with chronic pancreatitis requiring panceraticoduodenectomy. Based on available information, this recommendation appears to arise form the fact that the PPPD is less radical than the regular Whipple procedure, and some surgeons find it technically easier. Our experience fails to show a distinct superiority of the PPPD over the Whipple operation.<\/jats:p>","DOI":"10.1007\/s00268-003-7240-0","type":"journal-article","created":{"date-parts":[[2004,3,19]],"date-time":"2004-03-19T12:41:33Z","timestamp":1079700093000},"page":"1211-1216","source":"Crossref","is-referenced-by-count":62,"title":["Pylorus\u2010preserving Pancreaticoduodenectomy in the Treatment of Chronic Pancreatitis"],"prefix":"10.1002","volume":"27","author":[{"given":"Ramon E.","family":"Jimenez","sequence":"first","affiliation":[{"name":"Department of Surgery Hartford Hospital University of Connecticut School of Medicine 80 Seymour Street, P. O. Box 5037 Hartford Connecticut 06102 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Fernandez\u2010del Castillo","sequence":"additional","affiliation":[{"name":"Department of Surgery Massachusetts General Hospital Harvard Medical School 55 Fruit Street, WHT506 Boston Massachusetts 02114\u20102696 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David W.","family":"Rattner","sequence":"additional","affiliation":[{"name":"Department of Surgery Massachusetts General Hospital Harvard Medical School 55 Fruit Street, WHT506 Boston Massachusetts 02114\u20102696 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew L.","family":"Warshaw","sequence":"additional","affiliation":[{"name":"Department of Surgery Massachusetts General Hospital Harvard Medical School 55 Fruit Street, WHT506 Boston Massachusetts 02114\u20102696 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,10,13]]},"reference":[{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-193510000-00023"},{"key":"e_1_2_11_3_2","first-page":"711","article-title":"A one stage operation for the cure of carcinoma of the ampulla of Vater and the head of the pancreas","volume":"73","author":"Trimble IR","year":"1941","journal-title":"Surg. 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