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Preoperatively and at 1 year after surgery bone mineral content (BMC) in the distal radius and bone mineral density (BMD) in the lumbar spine and hip, as well as biochemical variables, were measured in 126 pHPT patients (95 women, 31\u00a0men). The mean \u00b1 SD age of the patients was 63 \u00b1 15 years. The mean \u00b1 SD serum calcium level was 2.78 \u00b1 0.16\u00a0mmol\/L. Altogether, 60% of the patients had a low oral calcium intake, and 18% had a 25\u2010hydroxyvitamin D<jats:sub>3<\/jats:sub> deficiency. Preoperatively, postmenopausal women had lower Z\u2010scores for BMD in the hip (<jats:italic>p<\/jats:italic> &lt; 0.001) and lumbar spine (<jats:italic>p<\/jats:italic> &lt; 0.05) than did premenopausal women. One year after surgery the bone density had increased in about 50% of the patients. The multiple logistic regression analysis showed that there was a weak association between the change in BMD in the hip, the serum 1,25\u2010dihydroxyvitamin D<jats:sub>3<\/jats:sub> level (<jats:italic>p<\/jats:italic> &lt; 0.05), and renal function (<jats:italic>p<\/jats:italic> &lt; 0.05), respectively. We concluded that about 50% of patients have increased bone mass after pHPT surgery, but the increase in the bone density is difficult to predict for the individual patient. Because many pHPT patients have low oral calcium intake and a vitamin D deficiency, it would be of interest to evaluate the role of postoperative calcium\/vitamin D supplements.<\/jats:p>","DOI":"10.1007\/s00268-004-7274-y","type":"journal-article","created":{"date-parts":[[2004,4,15]],"date-time":"2004-04-15T20:39:18Z","timestamp":1082061558000},"page":"502-507","source":"Crossref","is-referenced-by-count":44,"title":["Recovery of Bone Mineral Density in 126\u00a0Patients after Surgery for Primary Hyperparathyroidism"],"prefix":"10.1002","volume":"28","author":[{"given":"Erik","family":"Nordenstr\u00f6m","sequence":"first","affiliation":[{"name":"Department of Surgery Lund University Hospital S\u2010221 85 Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Westerdahl","sequence":"additional","affiliation":[{"name":"Department of Surgery Lund University Hospital S\u2010221 85 Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Bergenfelz","sequence":"additional","affiliation":[{"name":"Department of Surgery Lund University Hospital S\u2010221 85 Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,4,19]]},"reference":[{"key":"e_1_2_8_2_2","volume-title":"The Parathyroid Glands and Metabolic Bone Disease","author":"Albright F","year":"1948"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0007\u20101323.2001.01775.x"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S8756\u20103282(97)00078\u20101"},{"key":"e_1_2_8_5_2","first-page":"473","article-title":"Biochemical variables associated with bone density in patients with primary hyperparathyroidism","volume":"158","author":"Bergenfelz A","year":"1992","journal-title":"Eur. 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