{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T22:20:21Z","timestamp":1785795621978,"version":"3.56.0"},"reference-count":20,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2004,10,21]],"date-time":"2004-10-21T00:00:00Z","timestamp":1098316800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2004,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Some authors have praised the value of fine needle aspiration (FNA) with measurement of intraparathyroid intact parathyroid hormone (iPTH) for localization of the hypersecreting gland(s) in recurrent or persistent primary hyperparathyroidism (HPT). The aim of the present study was to determinate whether FNA for iPTH assay is an effective procedure to distinguish between normal and hypersecreting parathyroid glands. We performed a prospective study of 170 patients who underwent cervicotomy. They were divided into three groups: group A, 50 patients with thyroid diseases; group B, 100 patients with primary HPT; group C, 20 patients with secondary HPT. We performed intraoperative FNA for iPTH measurement from the thyroid, and from the normal and enlarged parathyroid glands, and we compared the different intraglandular iPTH assays. In group A, the intraparathyroid iPTH level was &lt; 1000 pg\/ml in 68% of the patients. In group B, in the pathological parathyroid gland iPTH was &gt; 1000\u00a0in 88%; conversely, in the normal adjacent parathyroid glands it was &lt; 1000\u00a0in 79%. In group C, intraparathyroid iPTH of enlarged glands was &gt; 1000\u00a0in 80%. Intrathyroid iPTH was &lt; 100 pg\/ml in 96% for the three groups. We conclude that FNA for intraglandular iPTH measurement is an effective tool for distinguishing between normal and pathological parathyroid glands in the setting of primary HPT (<jats:italic>p<\/jats:italic> &lt; 0.05), and between thyroid and parathyroid glands in groups A and B. But the procedure should be carried out in conjunction with the sestamibi scan and ultrasonography before surgical reintervention.<\/jats:p>","DOI":"10.1007\/s00268-004-7563-5","type":"journal-article","created":{"date-parts":[[2004,10,14]],"date-time":"2004-10-14T21:23:41Z","timestamp":1097789021000},"page":"1143-1147","source":"Crossref","is-referenced-by-count":39,"title":["Fine Needle Aspiration and Intraparathyroid Intact Parathyroid Hormone Measurement for Reoperative Parathyroid Surgery"],"prefix":"10.1002","volume":"28","author":[{"given":"Natacha K.","family":"Kiblut","sequence":"first","affiliation":[{"name":"Service de Chirurgie G\u00e9n\u00e9rale et Endocrinienne CHRU de Lille 59037 Lille Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010F\u00e9lix","family":"Cussac","sequence":"additional","affiliation":[{"name":"Service de Radiologie G\u00e9n\u00e9rale CHRU de Lille 59037 Lille Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beno\u00eet","family":"Soudan","sequence":"additional","affiliation":[{"name":"Service de Biochimie, Endocrinologie P\u00e9rinatale CHRU de Lille 59037 Lille Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen G.","family":"Farrell","sequence":"additional","affiliation":[{"name":"Service de Chirurgie G\u00e9n\u00e9rale et Endocrinienne CHRU de Lille 59037 Lille Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Armstrong","sequence":"additional","affiliation":[{"name":"Service de Chirurgie G\u00e9n\u00e9rale et Endocrinienne CHRU de Lille 59037 Lille Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Arnalsteen","sequence":"additional","affiliation":[{"name":"Service de Chirurgie G\u00e9n\u00e9rale et Endocrinienne CHRU de Lille 59037 Lille Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Biechlin","sequence":"additional","affiliation":[{"name":"Service de Chirurgie G\u00e9n\u00e9rale et Endocrinienne CHRU de Lille 59037 Lille Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis A.","family":"Delattre","sequence":"additional","affiliation":[{"name":"Service de Chirurgie G\u00e9n\u00e9rale et Endocrinienne CHRU de Lille 59037 Lille Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles A.G.","family":"Proye","sequence":"additional","affiliation":[{"name":"Service de Chirurgie G\u00e9n\u00e9rale et Endocrinienne CHRU de Lille 59037 Lille Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,10,21]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004230050113"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.148.1.6856859"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1390072"},{"key":"e_1_2_8_5_2","first-page":"29","article-title":"Preoperative localization in unilateral parathyroid surgery","volume":"156","author":"Ud\u00e9n P","year":"1990","journal-title":"Acta Chir. Scand."},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1996.01430200071013"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1994.01420320096019"},{"key":"e_1_2_8_8_2","first-page":"959","article-title":"Use of preoperative fine\u2010needle aspiration in patients undergoing reoperation for primary hyperparathyroidism","volume":"116","author":"MacFarlane MP","year":"1994","journal-title":"Surgery"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.155.1.3883415"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/028418519103200514"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.163.5.7976905"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002680010218"},{"key":"e_1_2_8_13_2","first-page":"461","article-title":"Les r\u00e9interventions en chirurgie parathyro\u00efdienne","volume":"120","author":"Proye C","year":"1983","journal-title":"J. Chir. (Paris)"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.148.3.6878704"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01728456"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.290.6464.284"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-62-743-981"},{"key":"e_1_2_8_18_2","first-page":"154","article-title":"Locating a parathyroid adenoma by ultrasonography and aspiration biopsy cytology","volume":"135","author":"Clark OH","year":"1981","journal-title":"West. J. Med."},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.1177\/028418518802900215"},{"key":"e_1_2_8_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002689900154"},{"key":"e_1_2_8_21_2","first-page":"65","article-title":"Fine needle aspiration cytology of parathyroid adenoma","volume":"30","author":"Mincione GP","year":"1986","journal-title":"Acta Cytol."}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-004-7563-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-004-7563-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-004-7563-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,24]],"date-time":"2023-12-24T11:36:02Z","timestamp":1703417762000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-004-7563-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,10,21]]},"references-count":20,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2004,11]]}},"alternative-id":["10.1007\/s00268-004-7563-5"],"URL":"https:\/\/doi.org\/10.1007\/s00268-004-7563-5","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,10,21]]}}}