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The secondary goal was to demonstrate the value of prospective and retrospective studies regarding the early results of surgery and the risk factors. The tertiary goal was to emphasize the benefits of this operation, and the fourth goal was to clarify the possible risk factors associated with laparoscopic repair of the duodenal ulcer. The Medline\/Pubmed database was used. Review was done after evaluation of 96 retrieved full\u2010text articles. Thirteen prospective and twelve retrospective studies were selected, grouped, and summarized. The spectrum of the retrospective studies\u2019 results are as follows: median overall morbidity rate 10.5 %, median conversion rate 7%, median hospital stay 7\u00a0days, and median postoperative mortality rate 0%. The following is the spectrum of results of the prospective studies: median overall morbidity rate was slightly less (6%); the median conversion rate was higher (15%); the median hospital stay was shorter (5\u00a0days) and the postoperative mortality was higher (3%). The risk factors identified were the same. Shock, delayed presentation (&gt; 24 hours), confounding medical condition, age &gt; 70 years, poor laparoscopic expertise, ASA III\u2010IV, and Boey score should be considered preoperative laparoscopic repair risk factors. Each of these factors independently should qualify as a criterion for open repair due to higher intraoperative risks as well as postoperative morbidity. Inadequate ulcer localization, large perforation size (defined by some as &gt; 6\u00a0mm diameter, and by others as &gt; 10\u00a0mm), and ulcers with friable edges are also considered as conversion risk factors.<\/jats:p>","DOI":"10.1007\/s00268-005-7705-4","type":"journal-article","created":{"date-parts":[[2005,8,29]],"date-time":"2005-08-29T14:10:13Z","timestamp":1125324613000},"page":"1299-1310","source":"Crossref","is-referenced-by-count":71,"title":["Management Strategies, Early Results, Benefits, and Risk Factors of Laparoscopic Repair of Perforated Peptic Ulcer"],"prefix":"10.1002","volume":"29","author":[{"given":"Raimundas","family":"Lunevicius","sequence":"first","affiliation":[{"name":"2nd Department of Abdominal Surgery, Clinic of General and Plastic Surgery, Orthopaedics, and Traumatology, Vilnius University Emergency Hospital Vilnius University Siltnamiu Street 29 LT\u201004130 Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matas","family":"Morkevicius","sequence":"additional","affiliation":[{"name":"2nd Department of Abdominal Surgery, Clinic of General and Plastic Surgery, Orthopaedics, and Traumatology, Vilnius University Emergency Hospital Vilnius University Siltnamiu Street 29 LT\u201004130 Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,9,8]]},"reference":[{"key":"e_1_2_13_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6109(16)45684-7"},{"key":"e_1_2_13_3_2","first-page":"359","article-title":"The sixth decision regarding perforated duodenal ulcer","volume":"6","author":"Lagoo S","year":"2002","journal-title":"J.S.L.S."},{"key":"e_1_2_13_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004649900515"},{"key":"e_1_2_13_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039\u20106109(05)70618\u20106"},{"key":"e_1_2_13_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002689910045"},{"key":"e_1_2_13_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.34.12.1666"},{"key":"e_1_2_13_8_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365529709025093"},{"key":"e_1_2_13_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1991.01410290085017"},{"key":"e_1_2_13_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-199701000-00003"},{"key":"e_1_2_13_11_2","first-page":"1007","article-title":"Laparoscopic patching of crack cocaine\u2010induced perforated ulcers","volume":"62","author":"Arrillaga A","year":"1996","journal-title":"Am\u2010Surg."},{"key":"e_1_2_13_12_2","first-page":"2523","article-title":"Association of cocaine and methamphetamine use with giant gastrointestinal ulcers","volume":"91","author":"Pecha RE","year":"1996","journal-title":"Am. 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