{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T18:03:57Z","timestamp":1776103437769,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2005,10,5]],"date-time":"2005-10-05T00:00:00Z","timestamp":1128470400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2005,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To determine the clinical efficacy of Roux\u2010en\u2010Y reconstruction (RY) after distal gastrectomy, we compared postoperative outcomes of patients who underwent RY or conventional Billroth I reconstruction (B\u2010I). A total of 50 patients were prospectively randomized to either B\u2010I or RY reconstruction, and complications, postoperative course, and nutritional status were compared. Bile reflux and inflammation in the remnant stomach and lower esophagus were evaluated by postoperative follow\u2010up endoscopy at 6\u00a0months. Operative time and blood loss as well as postoperative nutrition did not show significant differences between the two groups. As anticipated, 5 of 24 patients with RY reconstruction developed gastrojejunal stasis in the early postoperative period, which led to a longer postoperative hospital stay as compared with the B\u2010I group (mean \u00b1 S.D; B\u2010I; 19.0 \u00b1 6.2, RY; 31.8 \u00b1 21.7\u00a0days) (<jats:italic>P<\/jats:italic> &lt; 0.05). Endoscopic examination revealed that the frequency of bile reflux (<jats:italic>P<\/jats:italic> &lt; 0.01) and degree of inflammation in the remnant stomach (<jats:italic>P<\/jats:italic> &lt; 0.05) were less in the RY group than in the B\u2010I group. However, inflammatory findings in the lower esophagus were observed in 7 (27%) of B\u2010I, and 8 (35%) of the RY group, suggesting that late phase esophagitis was not improved in the RY group. Roux\u2010en\u2010Y reconstruction was effective in preventing duodenogastric reflux and resulting gastritis, but it did not prevent esophagitis. Because RY reconstruction induces the frequent complication of Roux\u2010en\u2010Y stasis, causing longer postoperative hospital stay, this method has limited advantages over B\u2010I anastomosis after distal gastrectomy.<\/jats:p>","DOI":"10.1007\/s00268-005-7830-0","type":"journal-article","created":{"date-parts":[[2005,10,20]],"date-time":"2005-10-20T14:00:30Z","timestamp":1129816830000},"page":"1415-1420","source":"Crossref","is-referenced-by-count":94,"title":["Prospective Randomized Trial Comparing Billroth I and Roux\u2010en\u2010Y Procedures after Distal Gastrectomy for Gastric Carcinoma"],"prefix":"10.1002","volume":"29","author":[{"given":"Makoto","family":"Ishikawa","sequence":"first","affiliation":[{"name":"Department of Surgery Division of Surgical Oncology The University of Tokyo 7\u20103\u20101 Hongo 113\u20108655 Bankyo\u2010ku Tokyo 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