{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T05:25:46Z","timestamp":1782451546862,"version":"3.54.5"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,2,7]],"date-time":"2007-02-07T00:00:00Z","timestamp":1170806400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Mucocele of the appendix is an infrequent event, representing 0.3%\u20130.7% of appendiceal pathology and 8% of appendiceal tumors. It is characterized by a located or diffuse distension of the appendix with a mucus\u2010filled lumen.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We describe 35 cases of mucocele of the appendix diagnosed at Ram\u00f3n y Cajal Hospital between January 1985 and January 2006.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 21\u00a0males and 14 females with a mean age of 52.7 years are described. Most cases manifested as abdominal pain located in right iliac fossa, but 2 cases were incidental findings at CT\u2010scan and 1 at ultrasonography, performed for other reasons. In 4 cases, mucocele coexisted with colorectal cancer and was an incidental finding during laparotomy performed for tumor resection. Ultrasonography and computed tomography (CT) scan helped to achieve a correct diagnosis. Preoperative diagnosis of mucocele was achieved in 29% of the cases; 88% of patients underwent appendectomy, 2 had ileocecal resection, and 2 others underwent right hemicolectomy. Pathology revealed mucous hyperplasia in 34% of the cases, simple mucocele in 29%, cystadenoma in 31%, and cystadenocarcinoma in 2 patients. Two other patients developed adenocarcinoma of the cecum 12 and 33\u00a0months after surgery, and one patient developed pseudomyxoma peritonei after 62\u00a0months, causing his death.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The pathologist is forced to do an exhaustive study, looking for inadvertent perforations that can change the good prognosis of mucocele. We recommend follow\u2010up of all patients with mucoceles, because sometimes they are associated with colorectal neoplasms and recurrence as pseudomyxoma peritonei.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-006-0454-1","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T10:23:59Z","timestamp":1172139839000},"page":"542-548","source":"Crossref","is-referenced-by-count":97,"title":["Mucocele of the Appendix"],"prefix":"10.1002","volume":"31","author":[{"given":"J.","family":"Ruiz\u2010Tovar","sequence":"first","affiliation":[{"name":"Department of Surgery University Hospital Ram\u00f3n y Cajal Crta Colmenar Km 9 100 28034 Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. Garc\u00eda","family":"Teruel","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital Ram\u00f3n y Cajal Crta Colmenar Km 9 100 28034 Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V. Morales","family":"Casti\u00f1eiras","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital Ram\u00f3n y Cajal Crta Colmenar Km 9 100 28034 Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Sanjuanbenito","family":"Dehesa","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital Ram\u00f3n y Cajal Crta Colmenar Km 9 100 28034 Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. L\u00f3pez","family":"Quind\u00f3s","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital Ram\u00f3n y Cajal Crta Colmenar Km 9 100 28034 Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Mart\u00ednez","family":"Molina","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital Ram\u00f3n y Cajal Crta Colmenar Km 9 100 28034 Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,2,7]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"481","article-title":"Sobre el llamado mucocele apendicular versus cistoadenoma mucinoso","volume":"75","author":"Pastor FA","year":"1989","journal-title":"Rev Esp Enf Dig"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097\u20100142(197312)32:6<1525::AID\u2010CNCR2820320632>3.0.CO;2\u2010C"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097\u20100142(197605)37:5<2511::AID\u2010CNCR2820370544>3.0.CO;2\u2010L"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20102007\u20101008979"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016\u20105107(97)70013\u20100"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2005.12.003"},{"key":"e_1_2_6_8_2","first-page":"35","article-title":"Mucocele apendicular. Revisi\u00f3n de la literatura y aportaci\u00f3n de 8 casos","volume":"76","author":"Serrano S\u00e1nchez PA","year":"1989","journal-title":"Rev Esp Enferm Dig"},{"key":"e_1_2_6_9_2","first-page":"401","article-title":"Appendiceal mucoceles and pseudomyxoma peritonei","volume":"175","author":"Landen S","year":"1992","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_6_10_2","first-page":"787","article-title":"Mucocele of the appendix: computed tomographic, endoscopic and pathologic correlation","volume":"87","author":"Isaacs KL","year":"1992","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478\u2010200308000\u201000006"},{"key":"e_1_2_6_12_2","first-page":"455","volume-title":"Gastrointestinal Pathology","author":"Morson BC","year":"1979"},{"key":"e_1_2_6_13_2","first-page":"539","article-title":"Revisi\u00f3n del t\u00e9rmino mucocele apendicular. Referencia especial al cistoadenoma de ap\u00e9ndice","volume":"64","author":"Gonz\u00e1lez JJ","year":"1983","journal-title":"Rev Esp Enferm Dig"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026615010989"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1159\/000016863"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(89)72860-1"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2004.23.1.117"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.159.1.1609724"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0009\u20109260(99)90687\u20106"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004728\u2010200305000\u201000001"},{"key":"e_1_2_6_21_2","first-page":"463","article-title":"Mucocele of the appendix. Retrospective study of 10 cases","volume":"82","author":"Souei\u2010Mhiri M","year":"2001","journal-title":"J Radiol"},{"key":"e_1_2_6_22_2","first-page":"762","article-title":"Cistoadenocarcinoma mucinoso de ap\u00e9ndice: diagn\u00f3stico endosc\u00f3pico","volume":"97","author":"Rivera PA","year":"2005","journal-title":"Rev Esp Enferm Dig"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097\u20100142(19920715)70:2<396::AID\u2010CNCR2820700205>3.0.CO;2\u2010A"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-006-0454-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-006-0454-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-006-0454-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T11:03:14Z","timestamp":1704711794000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-006-0454-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2,7]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["10.1007\/s00268-006-0454-1"],"URL":"https:\/\/doi.org\/10.1007\/s00268-006-0454-1","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,2,7]]}}}