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Therefore we designed a study in which pneumatic dilatation was compared to laparoscopic cardiomyotomy to which was added a partial posterior fundoplication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Results<\/jats:title><jats:p>A series of 51 patients (24\u00a0males, mean age 44 years) were randomly allocated to the therapeutic modalities (dilatation = 26, surgery = 25). All patients were followed for at least 12\u00a0months, and during that period the pneumatic dilatations strategy had significantly more treatment failures (<jats:italic>P<\/jats:italic>= 0.04). Only minor differences emerged between the study groups when symptoms, dysphagia scorings, and quality\u2010of\u2010life assessments were evaluated 12\u00a0months after initiation of therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Laparoscopic myotomy was found to be superior to an endoscopic balloon dilatation strategy in the treatment of achalasia when studied during the first 12\u00a0months after treatment.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-006-0600-9","type":"journal-article","created":{"date-parts":[[2007,2,16]],"date-time":"2007-02-16T15:09:40Z","timestamp":1171638580000},"page":"470-478","source":"Crossref","is-referenced-by-count":127,"title":["Pneumatic Dilatation or Laparoscopic Cardiomyotomy in the Management of Newly Diagnosed Idiopathic Achalasia"],"prefix":"10.1002","volume":"31","author":[{"given":"S.","family":"Kostic","sequence":"first","affiliation":[{"name":"Department of General Surgery Bor\u00e5s Central Hospital S\u2010501 82 Br\u00e4mhultsv\u00e4gen 53 Bor\u00e5s Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Kjellin","sequence":"additional","affiliation":[{"name":"Department of Surgery Karolinska University Hospital SE\u2010141 86 Huddinge Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Ruth","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Sahlgrenska University Hospital SE\u2010413 45 Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"L\u00f6nroth","sequence":"additional","affiliation":[{"name":"Department of Surgery Sahlgrenska University Hospital SE\u2010413 45 Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Johnsson","sequence":"additional","affiliation":[{"name":"Department of Surgery Sahlgrenska University Hospital SE\u2010413 45 Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Andersson","sequence":"additional","affiliation":[{"name":"Department of Radiology Sahlgrenska University Hospital SE\u2010413 45 Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Lundell","sequence":"additional","affiliation":[{"name":"Department of Surgery Karolinska University Hospital SE\u2010141 86 Huddinge Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,2]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572\u20100241.2005.41775.x"},{"key":"e_1_2_5_3_2","first-page":"316","volume-title":"Textbook of Gastrointestinal Radiology","author":"Ott DJ","year":"2000"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8553(21)00495-7"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.33.8.1011"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2001.22539"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440\u20101746.1999.01950.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1052-5157(18)30068-0"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(86)90876-0"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.2000.278.3.G376"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.49.6.813"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20102036.2001.01065.x"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004836\u2010200303000\u201000005"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464\u2010003\u20108910\u20106"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1159\/000079341"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010199711000\u201000009"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365529609095544"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365529309098350"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650\u2010198903001\u201000018"},{"key":"e_1_2_5_20_2","first-page":"170","volume-title":"Assessment of Quality of Life in Clinical Trials of Cardiovascular Therapies","author":"Dupuy HJ","year":"1984"},{"key":"e_1_2_5_21_2","doi-asserted-by":"crossref","unstructured":"SvedlundJ Sj\u00f6dinI DotevallG. 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