{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T05:43:58Z","timestamp":1775454238823,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2007,5,30]],"date-time":"2007-05-30T00:00:00Z","timestamp":1180483200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"},{"start":{"date-parts":[[2007,5,30]],"date-time":"2007-05-30T00:00:00Z","timestamp":1180483200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"},{"start":{"date-parts":[[2007,5,30]],"date-time":"2007-05-30T00:00:00Z","timestamp":1180483200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The Nuss procedure was introduced at our center in 1999. The operation was mainly performed for cosmesis. Little information is available regarding the influence of this operation on lung function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The aim of this study, a prospective analysis, was to analyze the effect of the Nuss procedure on lung function variables. Between 1999 and 2007 a total of 203 patients with pectus excavatum were treated with the Nuss procedure, of whom 145 (104\u00a0male, 41 female) were located at Emma Children\u2019s Hospital. In the latter subset of consecutive patients, static lung function variables [total lung capacity (TLC), functional residual capacity (FRC), vital capacity (VC)] and dynamic lung function variables [forced expired volume in 1 s (FEV<jats:sub>1<\/jats:sub>), maximum expiratory flow (MEF<jats:sub>50<\/jats:sub>)] were performed using spirometry and body box measurements at four time points: prior to operation (T0), 6\u00a0months after the Nuss procedure (T1, <jats:italic>n<\/jats:italic> = 111), prior to removal of the Nuss bar (T2, <jats:italic>n<\/jats:italic> = 74), and 6\u00a0months after removal (T3, <jats:italic>n<\/jats:italic> = 53). All values were expressed as a percent of normal values for sex, age, and height. Results were compared with a paired\u2010samples <jats:italic>t\u2010<\/jats:italic>test, with the level of significance at <jats:italic>p<\/jats:italic> = 0.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 6\u00a0months after bar insertion the TLC, FRC, VC, FEV<jats:sub>1<\/jats:sub>, and MEF<jats:sub>50<\/jats:sub> showed a significant increase; and prior to bar removal the FRC and MEF<jats:sub>50<\/jats:sub> showed significantly increased values. At 6\u00a0months after Nuss bar removal, none of the lung function variables showed any significant change compared to the preoperative values.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>After the Nuss procedure for pectus excavatum, there was no improvement of pulmonary function, but neither was the patient\u2019s pulmonary function harmed by resolving a largely cosmetic problem.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-007-9081-8","type":"journal-article","created":{"date-parts":[[2007,5,29]],"date-time":"2007-05-29T13:06:39Z","timestamp":1180443999000},"page":"1518-1522","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Lung Function after the Minimal Invasive Pectus Excavatum Repair (Nuss Procedure)"],"prefix":"10.1002","volume":"31","author":[{"given":"Daniel C.","family":"Aronson","sequence":"first","affiliation":[{"name":"Pediatric Surgical Center of Amsterdam Emma Children\u2019s Hospital AMC and VU Medical Center PO Box 22700 1100 DE Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Remko P.","family":"Bosgraaf","sequence":"additional","affiliation":[{"name":"Pediatric Surgical Center of Amsterdam Emma Children\u2019s Hospital AMC and VU Medical Center PO Box 22700 1100 DE Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva\u2010Maria","family":"Merz","sequence":"additional","affiliation":[{"name":"Department of Special Education Vrije Universiteit Amsterdam vd Boechorststraat 1 1081 BT Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reindert P.","family":"van Steenwijk","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical Lung Fysiology Academic Medical Center 1100 DE Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wim M. C.","family":"van Aalderen","sequence":"additional","affiliation":[{"name":"Division of Pediatric Pulmonology Emma Children\u2019s Hospital AMC, Academic Medical Center Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robertine","family":"van Baren","sequence":"additional","affiliation":[{"name":"Pediatric Surgical Center of Amsterdam Emma Children\u2019s Hospital AMC and VU Medical Center PO Box 22700 1100 DE Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,5,30]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010194904000\u201000002"},{"key":"e_1_2_6_3_2","first-page":"564","article-title":"Symptomatic pectus deformities of the chest","volume":"126","author":"Castile R","year":"1982","journal-title":"Am Rev Respir Dis"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.95.4.850"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.105.6.1646"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022\u20103476(96)80128\u20104"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022\u20103468(84)80268\u20107"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022\u20103468(98)90314\u20101"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2003.50112"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2003.50118"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2004.09.040"},{"key":"e_1_2_6_12_2","first-page":"114","article-title":"Lung function in children and adolescents: methods, reference values","volume":"22","author":"Zapletal A","year":"1987","journal-title":"Prog Respir Res"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.3.870"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2005.12.009"},{"key":"e_1_2_6_15_2","first-page":"41","article-title":"Impairment of cardiac function in patients with pectus excavatum with improvement after operative correction","volume":"99","author":"Beiser G","year":"1972","journal-title":"N Engl J Med"},{"key":"e_1_2_6_16_2","first-page":"125","article-title":"Cardiorespiratory function is significantly improved following corrective surgery for severe pectus excavatum","volume":"41","author":"Haller JA","year":"2000","journal-title":"J Cardiovasc Surg"},{"key":"e_1_2_6_17_2","first-page":"245","article-title":"Cardiopulmonary effects of anterior chest wall deformities","volume":"10","author":"Shamburger RC","year":"2000","journal-title":"Chest Surg Clin N Am"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-007-9081-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00268-007-9081-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-007-9081-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-007-9081-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T11:05:27Z","timestamp":1704711927000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-007-9081-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5,30]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["10.1007\/s00268-007-9081-8"],"URL":"https:\/\/doi.org\/10.1007\/s00268-007-9081-8","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,5,30]]},"assertion":[{"value":"25 November 2006","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 February 2007","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 May 2007","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}