{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T05:11:24Z","timestamp":1784178684692,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2007,7,15]],"date-time":"2007-07-15T00:00:00Z","timestamp":1184457600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Typhoid fever (TF) is a severe febrile illness caused by <jats:italic>Salmonella typhi<\/jats:italic>. One of the most lethal complications of TF is ileal perforation (TIP). Although the mortality of associated with TIP has decreased slightly over the past decade, it is still high.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>The records of the 82 surgically treated patients with TIP were evaluated retrospectively. There were 64\u00a0men with the mean age of 36.3 years (range: 7\u201368 years). In surgical treatment, debridement with primary closure was performed in 32 patients (39.0%), and wedge resection with primary closure was performed in 9 (11. 0%), resection with primary anastomosis in 9 (11.0%), and resection with ileostomy in 32 (39.0%). The most common postoperative complication was wound infection, which occurred in 24 patients (29.3%). The overall morbidity was highest in the ileostomy group. The overall mortality was 11.0% (9 patients). Age, gender, number, and localization of the perforations (<jats:italic>p<\/jats:italic> &gt; 0.05) were not found to affect mortality, but prolonged preoperative period (<jats:italic>p<\/jats:italic> &lt; 0.001), extended peritoneal contamination (<jats:italic>p<\/jats:italic> &lt; 0.01), and ileostomy procedure (<jats:italic>p<\/jats:italic> &lt; 0.001) were found to influence the increase in mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Early and appropriate surgical intervention with effective preoperative and postoperative care may improve survival in TIP.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00268-007-9141-0","type":"journal-article","created":{"date-parts":[[2007,7,16]],"date-time":"2007-07-16T23:42:33Z","timestamp":1184629353000},"page":"1883-1888","source":"Crossref","is-referenced-by-count":36,"title":["Typhoid Intestinal Perforations: Twenty\u2010six Year Experience"],"prefix":"10.1002","volume":"31","author":[{"given":"S. Selcuk","family":"Atamanalp","sequence":"first","affiliation":[{"name":"Department of General Surgery Atat\u00fcrk University, School of Medicine 25070 Erzurum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bulent","family":"Aydinli","sequence":"additional","affiliation":[{"name":"Department of General Surgery Atat\u00fcrk University, School of Medicine 25070 Erzurum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gurkan","family":"Ozturk","sequence":"additional","affiliation":[{"name":"Department of General Surgery Atat\u00fcrk University, School of Medicine 25070 Erzurum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Durkaya","family":"Oren","sequence":"additional","affiliation":[{"name":"Department of General Surgery Atat\u00fcrk University, School of Medicine 25070 Erzurum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmut","family":"Basoglu","sequence":"additional","affiliation":[{"name":"Department of General Surgery Atat\u00fcrk University, School of Medicine 25070 Erzurum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Ilhan","family":"Yildirgan","sequence":"additional","affiliation":[{"name":"Department of General Surgery Atat\u00fcrk University, School of Medicine 25070 Erzurum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,7,15]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwh172"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s003830100008"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra020201"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2004.11.032"},{"key":"e_1_2_5_6_2","first-page":"395","article-title":"The prognostic factors in typhoid ileal perforation: a prospective study of 50 patients","volume":"42","author":"Adesunkanmi ARK","year":"2002","journal-title":"JR Coll Surg Edinb"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1023\/B:DDAS.0000011620.56077.97"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-002-0794-3"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s003830050435"},{"key":"e_1_2_5_10_2","first-page":"124","article-title":"Intestinal perforations due to Typhus","volume":"3","author":"Oren D","year":"1991","journal-title":"Turk J Dis Colon Rectum"},{"key":"e_1_2_5_11_2","first-page":"172","article-title":"Comparative study of operative procedures in typhoid perforation","volume":"65","author":"Beniwal U","year":"2003","journal-title":"Indian J Surg"},{"key":"e_1_2_5_12_2","first-page":"139","article-title":"Established peritonitis due to typhoid perforation","volume":"1","author":"Fernandez\u2010Mena C","year":"2003","journal-title":"Electron J Biomed"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002689900388"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800821120"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002\u20109610(89)90591\u20106"},{"key":"e_1_2_5_16_2","first-page":"69","article-title":"Typhoid perforation in Maiduguri, Nigeria","volume":"3","author":"Na\u2019aya HU","year":"2004","journal-title":"Ann Afr Med"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1080\/02724939992356"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800840436"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1983.01390110027007"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.sle.0000129387.76641.29"},{"key":"e_1_2_5_21_2","first-page":"399","article-title":"Laparoscopic repair of small bowel perforation","volume":"9","author":"Sinha R","year":"2005","journal-title":"JSLS"}],"container-title":["World Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00268-007-9141-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00268-007-9141-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00268-007-9141-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T15:00:45Z","timestamp":1703602845000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1007\/s00268-007-9141-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7,15]]},"references-count":20,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["10.1007\/s00268-007-9141-0"],"URL":"https:\/\/doi.org\/10.1007\/s00268-007-9141-0","archive":["Portico"],"relation":{},"ISSN":["0364-2313","1432-2323"],"issn-type":[{"value":"0364-2313","type":"print"},{"value":"1432-2323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,7,15]]}}}