{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,19]],"date-time":"2025-04-19T06:46:23Z","timestamp":1745045183959},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2008,1,18]],"date-time":"2008-01-18T00:00:00Z","timestamp":1200614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World j. surg."],"published-print":{"date-parts":[[2008,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Surgical treatment of patients with congestive heart failure (CHF) has steadily advanced from rescue procedures such as aneurysmectomy, rupture repair, ventricular assist devices (VADs), and transplantation to procedures that can prevent or delay the progression of cardiac dysfunction and failure. The latter include operations such as coronary artery bypass grafting (CABG) and mitral valve repair for patients with ischemic cardiomyopathy (ICMP) and mitral annular dilatation, ventricular restoration and remodeling, and cardiac resynchronization therapy. As the number of heart transplants reported worldwide continues to decline over the past decade (by over 30%), newer surgical therapies have emerged. A need arises for clinical registries such as the NIH\u2010sponsored LVAD registry and registries for biventricular pacing and AICD implantation, for total artificial heart implants, and for mitral valve repair in patients with ICMP. Prospective trials comparing sole ventricular restoration therapy (SVR) to SVR with concomitant CABG\/MVR, coronary sinus versus epicardial LV pacing for ventricular resynchronization therapy, trials comparing LVAD as destination therapy to AICD implants, mitral valve repair versus chordal\u2010sparing valve replacement for ischemic and valvular cardiomyopathy, and off\u2010pump versus on\u2010pump CABG for patients with ICMP are urgently needed. Future research should also be directed toward drugs targeting \u201cB\u2010cell mediated\u201d humeral vascular rejection\u2014the Achilles heel of cardiac transplantation, xenotransplantation, permanently implantable VADs, gene therapy, and myocardial cell regeneration therapy.<\/jats:p>","DOI":"10.1007\/s00268-007-9417-4","type":"journal-article","created":{"date-parts":[[2008,1,17]],"date-time":"2008-01-17T20:52:42Z","timestamp":1200603162000},"page":"375-380","source":"Crossref","is-referenced-by-count":3,"title":["A Perspective on the Surgical Management of Congestive Heart Failure"],"prefix":"10.1002","volume":"32","author":[{"given":"Malek G.","family":"Massad","sequence":"first","affiliation":[{"name":"Division of Cardiothoracic Surgery University of Illinois at Chicago College of Medicine 840 S. 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